Amino acid dipepetide frequency for Trema orientale (Charcoal tree) (Celtis orientalis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.226AlaAla: 6.226 ± 0.035	1.218AlaCys: 1.218 ± 0.012	2.934AlaAsp: 2.934 ± 0.017	4.156AlaGlu: 4.156 ± 0.023	2.747AlaPhe: 2.747 ± 0.014	4.053AlaGly: 4.053 ± 0.021	1.344AlaHis: 1.344 ± 0.01	3.737AlaIle: 3.737 ± 0.021	3.777AlaLys: 3.777 ± 0.025	6.66AlaLeu: 6.66 ± 0.029	1.676AlaMet: 1.676 ± 0.013	2.53AlaAsn: 2.53 ± 0.017	2.78AlaPro: 2.78 ± 0.023	2.099AlaGln: 2.099 ± 0.016	3.389AlaArg: 3.389 ± 0.017	5.933AlaSer: 5.933 ± 0.027	3.489AlaThr: 3.489 ± 0.019	4.717AlaVal: 4.717 ± 0.025	0.777AlaTrp: 0.777 ± 0.008	1.757AlaTyr: 1.757 ± 0.013	0.001AlaXaa: 0.001 ± 0.0
Cys	0.94CysAla: 0.94 ± 0.01	0.515CysCys: 0.515 ± 0.009	0.84CysAsp: 0.84 ± 0.01	0.868CysGlu: 0.868 ± 0.011	0.937CysPhe: 0.937 ± 0.011	1.395CysGly: 1.395 ± 0.013	0.482CysHis: 0.482 ± 0.007	0.946CysIle: 0.946 ± 0.01	1.083CysLys: 1.083 ± 0.011	1.914CysLeu: 1.914 ± 0.016	0.414CysMet: 0.414 ± 0.006	0.825CysAsn: 0.825 ± 0.009	0.959CysPro: 0.959 ± 0.011	0.603CysGln: 0.603 ± 0.007	1.089CysArg: 1.089 ± 0.011	1.845CysSer: 1.845 ± 0.016	0.84CysThr: 0.84 ± 0.009	1.057CysVal: 1.057 ± 0.01	0.257CysTrp: 0.257 ± 0.005	0.535CysTyr: 0.535 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	3.171AspAla: 3.171 ± 0.019	0.957AspCys: 0.957 ± 0.009	3.715AspAsp: 3.715 ± 0.028	3.925AspGlu: 3.925 ± 0.026	2.361AspPhe: 2.361 ± 0.015	3.696AspGly: 3.696 ± 0.023	1.47AspHis: 1.47 ± 0.013	2.888AspIle: 2.888 ± 0.019	2.581AspLys: 2.581 ± 0.017	5.122AspLeu: 5.122 ± 0.022	1.235AspMet: 1.235 ± 0.01	2.081AspAsn: 2.081 ± 0.015	2.601AspPro: 2.601 ± 0.016	1.895AspGln: 1.895 ± 0.015	2.482AspArg: 2.482 ± 0.017	4.234AspSer: 4.234 ± 0.02	2.066AspThr: 2.066 ± 0.012	3.564AspVal: 3.564 ± 0.018	0.712AspTrp: 0.712 ± 0.008	1.546AspTyr: 1.546 ± 0.012	0.001AspXaa: 0.001 ± 0.0
Glu	4.711GluAla: 4.711 ± 0.027	0.877GluCys: 0.877 ± 0.009	3.861GluAsp: 3.861 ± 0.025	6.223GluGlu: 6.223 ± 0.038	2.419GluPhe: 2.419 ± 0.015	3.698GluGly: 3.698 ± 0.021	1.204GluHis: 1.204 ± 0.012	3.724GluIle: 3.724 ± 0.019	4.66GluLys: 4.66 ± 0.027	6.086GluLeu: 6.086 ± 0.032	1.663GluMet: 1.663 ± 0.014	3.134GluAsn: 3.134 ± 0.019	2.182GluPro: 2.182 ± 0.016	2.032GluGln: 2.032 ± 0.015	3.495GluArg: 3.495 ± 0.02	4.654GluSer: 4.654 ± 0.023	3.084GluThr: 3.084 ± 0.018	4.159GluVal: 4.159 ± 0.022	0.746GluTrp: 0.746 ± 0.008	1.622GluTyr: 1.622 ± 0.013	0.001GluXaa: 0.001 ± 0.0
Phe	2.482PheAla: 2.482 ± 0.018	0.923PheCys: 0.923 ± 0.009	2.414PheAsp: 2.414 ± 0.017	2.394PheGlu: 2.394 ± 0.015	2.17PhePhe: 2.17 ± 0.02	3.216PheGly: 3.216 ± 0.02	1.137PheHis: 1.137 ± 0.01	2.085PheIle: 2.085 ± 0.015	2.127PheLys: 2.127 ± 0.015	4.499PheLeu: 4.499 ± 0.024	0.966PheMet: 0.966 ± 0.009	1.753PheAsn: 1.753 ± 0.013	2.132PhePro: 2.132 ± 0.017	1.542PheGln: 1.542 ± 0.011	2.192PheArg: 2.192 ± 0.017	4.296PheSer: 4.296 ± 0.02	1.98PheThr: 1.98 ± 0.015	2.846PheVal: 2.846 ± 0.017	0.632PheTrp: 0.632 ± 0.008	1.297PheTyr: 1.297 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	3.909GlyAla: 3.909 ± 0.021	1.289GlyCys: 1.289 ± 0.013	3.371GlyAsp: 3.371 ± 0.019	3.713GlyGlu: 3.713 ± 0.021	3.296GlyPhe: 3.296 ± 0.019	5.661GlyGly: 5.661 ± 0.053	1.554GlyHis: 1.554 ± 0.012	3.55GlyIle: 3.55 ± 0.022	3.942GlyLys: 3.942 ± 0.021	6.255GlyLeu: 6.255 ± 0.025	1.387GlyMet: 1.387 ± 0.011	3.006GlyAsn: 3.006 ± 0.018	2.588GlyPro: 2.588 ± 0.018	2.077GlyGln: 2.077 ± 0.016	3.725GlyArg: 3.725 ± 0.021	6.037GlySer: 6.037 ± 0.03	3.202GlyThr: 3.202 ± 0.02	4.303GlyVal: 4.303 ± 0.023	0.911GlyTrp: 0.911 ± 0.009	2.02GlyTyr: 2.02 ± 0.016	0.001GlyXaa: 0.001 ± 0.0
His	1.31HisAla: 1.31 ± 0.012	0.536HisCys: 0.536 ± 0.007	1.263HisAsp: 1.263 ± 0.012	1.277HisGlu: 1.277 ± 0.012	1.099HisPhe: 1.099 ± 0.01	1.759HisGly: 1.759 ± 0.014	1.151HisHis: 1.151 ± 0.019	1.199HisIle: 1.199 ± 0.011	1.15HisLys: 1.15 ± 0.01	2.473HisLeu: 2.473 ± 0.018	0.523HisMet: 0.523 ± 0.007	1.001HisAsn: 1.001 ± 0.01	1.323HisPro: 1.323 ± 0.012	1.032HisGln: 1.032 ± 0.009	1.42HisArg: 1.42 ± 0.01	1.943HisSer: 1.943 ± 0.014	0.945HisThr: 0.945 ± 0.01	1.582HisVal: 1.582 ± 0.012	0.313HisTrp: 0.313 ± 0.005	0.726HisTyr: 0.726 ± 0.008	0.001HisXaa: 0.001 ± 0.0
Ile	3.454IleAla: 3.454 ± 0.022	1.058IleCys: 1.058 ± 0.01	2.838IleAsp: 2.838 ± 0.019	3.173IleGlu: 3.173 ± 0.018	2.362IlePhe: 2.362 ± 0.014	3.412IleGly: 3.412 ± 0.02	1.276IleHis: 1.276 ± 0.012	2.847IleIle: 2.847 ± 0.019	2.868IleLys: 2.868 ± 0.017	5.263IleLeu: 5.263 ± 0.023	1.151IleMet: 1.151 ± 0.011	2.184IleAsn: 2.184 ± 0.014	2.934IlePro: 2.934 ± 0.02	1.891IleGln: 1.891 ± 0.015	2.774IleArg: 2.774 ± 0.019	4.967IleSer: 4.967 ± 0.022	2.589IleThr: 2.589 ± 0.014	3.447IleVal: 3.447 ± 0.02	0.75IleTrp: 0.75 ± 0.009	1.473IleTyr: 1.473 ± 0.013	0.001IleXaa: 0.001 ± 0.0
Lys	3.957LysAla: 3.957 ± 0.021	0.963LysCys: 0.963 ± 0.011	3.135LysAsp: 3.135 ± 0.018	4.503LysGlu: 4.503 ± 0.027	2.156LysPhe: 2.156 ± 0.015	3.493LysGly: 3.493 ± 0.018	1.263LysHis: 1.263 ± 0.011	3.172LysIle: 3.172 ± 0.016	4.614LysLys: 4.614 ± 0.033	6.063LysLeu: 6.063 ± 0.03	1.424LysMet: 1.424 ± 0.01	2.652LysAsn: 2.652 ± 0.016	2.756LysPro: 2.756 ± 0.02	2.113LysGln: 2.113 ± 0.016	3.656LysArg: 3.656 ± 0.02	4.608LysSer: 4.608 ± 0.024	2.86LysThr: 2.86 ± 0.016	3.756LysVal: 3.756 ± 0.017	0.792LysTrp: 0.792 ± 0.008	1.59LysTyr: 1.59 ± 0.014	0.001LysXaa: 0.001 ± 0.0
Leu	6.527LeuAla: 6.527 ± 0.027	1.868LeuCys: 1.868 ± 0.015	5.167LeuAsp: 5.167 ± 0.023	6.434LeuGlu: 6.434 ± 0.029	4.057LeuPhe: 4.057 ± 0.02	6.114LeuGly: 6.114 ± 0.026	2.537LeuHis: 2.537 ± 0.015	4.818LeuIle: 4.818 ± 0.025	6.144LeuLys: 6.144 ± 0.029	10.282LeuLeu: 10.282 ± 0.043	2.154LeuMet: 2.154 ± 0.014	4.006LeuAsn: 4.006 ± 0.02	5.239LeuPro: 5.239 ± 0.025	4.043LeuGln: 4.043 ± 0.022	5.823LeuArg: 5.823 ± 0.027	8.994LeuSer: 8.994 ± 0.046	4.581LeuThr: 4.581 ± 0.025	6.766LeuVal: 6.766 ± 0.029	1.209LeuTrp: 1.209 ± 0.012	2.543LeuTyr: 2.543 ± 0.018	0.002LeuXaa: 0.002 ± 0.0
Met	2.191MetAla: 2.191 ± 0.015	0.309MetCys: 0.309 ± 0.005	1.313MetAsp: 1.313 ± 0.012	1.899MetGlu: 1.899 ± 0.013	0.784MetPhe: 0.784 ± 0.009	1.586MetGly: 1.586 ± 0.014	0.47MetHis: 0.47 ± 0.007	1.195MetIle: 1.195 ± 0.012	1.522MetLys: 1.522 ± 0.012	2.03MetLeu: 2.03 ± 0.013	0.624MetMet: 0.624 ± 0.009	0.952MetAsn: 0.952 ± 0.01	0.984MetPro: 0.984 ± 0.01	0.789MetGln: 0.789 ± 0.008	1.198MetArg: 1.198 ± 0.01	1.721MetSer: 1.721 ± 0.013	1.022MetThr: 1.022 ± 0.009	1.667MetVal: 1.667 ± 0.014	0.266MetTrp: 0.266 ± 0.005	0.563MetTyr: 0.563 ± 0.008	0.001MetXaa: 0.001 ± 0.0
Asn	2.506AsnAla: 2.506 ± 0.016	0.838AsnCys: 0.838 ± 0.01	2.19AsnAsp: 2.19 ± 0.021	2.489AsnGlu: 2.489 ± 0.016	1.97AsnPhe: 1.97 ± 0.016	3.314AsnGly: 3.314 ± 0.022	1.111AsnHis: 1.111 ± 0.012	2.449AsnIle: 2.449 ± 0.015	2.378AsnLys: 2.378 ± 0.015	4.705AsnLeu: 4.705 ± 0.029	1.068AsnMet: 1.068 ± 0.01	2.447AsnAsn: 2.447 ± 0.022	2.4AsnPro: 2.4 ± 0.017	1.677AsnGln: 1.677 ± 0.014	2.099AsnArg: 2.099 ± 0.014	3.999AsnSer: 3.999 ± 0.02	1.969AsnThr: 1.969 ± 0.015	2.742AsnVal: 2.742 ± 0.016	0.592AsnTrp: 0.592 ± 0.007	1.311AsnTyr: 1.311 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	2.964ProAla: 2.964 ± 0.018	0.78ProCys: 0.78 ± 0.01	2.455ProAsp: 2.455 ± 0.017	3.131ProGlu: 3.131 ± 0.02	2.052ProPhe: 2.052 ± 0.014	2.668ProGly: 2.668 ± 0.018	1.162ProHis: 1.162 ± 0.011	2.416ProIle: 2.416 ± 0.016	2.817ProLys: 2.817 ± 0.019	4.513ProLeu: 4.513 ± 0.024	0.922ProMet: 0.922 ± 0.009	2.407ProAsn: 2.407 ± 0.017	4.027ProPro: 4.027 ± 0.046	1.783ProGln: 1.783 ± 0.015	2.512ProArg: 2.512 ± 0.016	5.196ProSer: 5.196 ± 0.027	2.671ProThr: 2.671 ± 0.018	3.052ProVal: 3.052 ± 0.02	0.622ProTrp: 0.622 ± 0.008	1.31ProTyr: 1.31 ± 0.012	0.002ProXaa: 0.002 ± 0.0
Gln	2.321GlnAla: 2.321 ± 0.013	0.568GlnCys: 0.568 ± 0.008	1.591GlnAsp: 1.591 ± 0.012	2.249GlnGlu: 2.249 ± 0.016	1.345GlnPhe: 1.345 ± 0.01	2.02GlnGly: 2.02 ± 0.015	0.865GlnHis: 0.865 ± 0.01	1.966GlnIle: 1.966 ± 0.013	2.194GlnLys: 2.194 ± 0.016	3.538GlnLeu: 3.538 ± 0.021	0.888GlnMet: 0.888 ± 0.01	1.808GlnAsn: 1.808 ± 0.014	1.738GlnPro: 1.738 ± 0.015	1.836GlnGln: 1.836 ± 0.029	2.108GlnArg: 2.108 ± 0.015	2.834GlnSer: 2.834 ± 0.019	1.713GlnThr: 1.713 ± 0.013	2.361GlnVal: 2.361 ± 0.014	0.455GlnTrp: 0.455 ± 0.006	0.93GlnTyr: 0.93 ± 0.011	0.001GlnXaa: 0.001 ± 0.0
Arg	3.367ArgAla: 3.367 ± 0.021	0.994ArgCys: 0.994 ± 0.011	2.749ArgAsp: 2.749 ± 0.018	3.489ArgGlu: 3.489 ± 0.021	2.339ArgPhe: 2.339 ± 0.017	3.335ArgGly: 3.335 ± 0.019	1.369ArgHis: 1.369 ± 0.01	2.923ArgIle: 2.923 ± 0.017	3.778ArgLys: 3.778 ± 0.02	5.294ArgLeu: 5.294 ± 0.028	1.292ArgMet: 1.292 ± 0.011	2.546ArgAsn: 2.546 ± 0.014	2.528ArgPro: 2.528 ± 0.019	1.815ArgGln: 1.815 ± 0.014	4.343ArgArg: 4.343 ± 0.027	4.565ArgSer: 4.565 ± 0.027	2.602ArgThr: 2.602 ± 0.015	3.564ArgVal: 3.564 ± 0.019	0.772ArgTrp: 0.772 ± 0.009	1.432ArgTyr: 1.432 ± 0.011	0.001ArgXaa: 0.001 ± 0.0
Ser	5.331SerAla: 5.331 ± 0.025	1.713SerCys: 1.713 ± 0.015	4.375SerAsp: 4.375 ± 0.021	4.874SerGlu: 4.874 ± 0.025	4.234SerPhe: 4.234 ± 0.021	6.031SerGly: 6.031 ± 0.031	2.074SerHis: 2.074 ± 0.012	4.514SerIle: 4.514 ± 0.019	4.896SerLys: 4.896 ± 0.021	9.163SerLeu: 9.163 ± 0.042	2.032SerMet: 2.032 ± 0.013	4.133SerAsn: 4.133 ± 0.024	4.662SerPro: 4.662 ± 0.032	3.007SerGln: 3.007 ± 0.02	4.589SerArg: 4.589 ± 0.024	11.704SerSer: 11.704 ± 0.058	4.99SerThr: 4.99 ± 0.02	5.277SerVal: 5.277 ± 0.021	1.254SerTrp: 1.254 ± 0.012	2.376SerTyr: 2.376 ± 0.013	0.002SerXaa: 0.002 ± 0.0
Thr	3.306ThrAla: 3.306 ± 0.02	0.918ThrCys: 0.918 ± 0.011	2.185ThrAsp: 2.185 ± 0.015	2.712ThrGlu: 2.712 ± 0.016	2.029ThrPhe: 2.029 ± 0.015	3.194ThrGly: 3.194 ± 0.02	1.055ThrHis: 1.055 ± 0.011	2.77ThrIle: 2.77 ± 0.016	2.763ThrLys: 2.763 ± 0.019	4.776ThrLeu: 4.776 ± 0.022	1.139ThrMet: 1.139 ± 0.009	2.149ThrAsn: 2.149 ± 0.015	2.582ThrPro: 2.582 ± 0.018	1.542ThrGln: 1.542 ± 0.013	2.565ThrArg: 2.565 ± 0.017	4.75ThrSer: 4.75 ± 0.023	3.395ThrThr: 3.395 ± 0.03	3.238ThrVal: 3.238 ± 0.019	0.671ThrTrp: 0.671 ± 0.007	1.348ThrTyr: 1.348 ± 0.013	0.001ThrXaa: 0.001 ± 0.0
Val	4.807ValAla: 4.807 ± 0.024	1.131ValCys: 1.131 ± 0.011	3.703ValAsp: 3.703 ± 0.021	4.447ValGlu: 4.447 ± 0.022	2.847ValPhe: 2.847 ± 0.02	4.297ValGly: 4.297 ± 0.022	1.507ValHis: 1.507 ± 0.013	3.379ValIle: 3.379 ± 0.019	3.787ValLys: 3.787 ± 0.018	6.563ValLeu: 6.563 ± 0.027	1.492ValMet: 1.492 ± 0.011	2.576ValAsn: 2.576 ± 0.015	3.282ValPro: 3.282 ± 0.018	2.212ValGln: 2.212 ± 0.017	3.292ValArg: 3.292 ± 0.017	5.587ValSer: 5.587 ± 0.026	3.175ValThr: 3.175 ± 0.018	5.344ValVal: 5.344 ± 0.029	0.802ValTrp: 0.802 ± 0.008	1.895ValTyr: 1.895 ± 0.016	0.001ValXaa: 0.001 ± 0.0
Trp	0.81TrpAla: 0.81 ± 0.01	0.247TrpCys: 0.247 ± 0.005	0.692TrpAsp: 0.692 ± 0.007	0.759TrpGlu: 0.759 ± 0.009	0.563TrpPhe: 0.563 ± 0.008	0.769TrpGly: 0.769 ± 0.009	0.293TrpHis: 0.293 ± 0.005	0.713TrpIle: 0.713 ± 0.008	0.928TrpLys: 0.928 ± 0.01	1.315TrpLeu: 1.315 ± 0.013	0.331TrpMet: 0.331 ± 0.005	0.727TrpAsn: 0.727 ± 0.01	0.534TrpPro: 0.534 ± 0.008	0.44TrpGln: 0.44 ± 0.007	0.893TrpArg: 0.893 ± 0.009	1.034TrpSer: 1.034 ± 0.011	0.674TrpThr: 0.674 ± 0.008	0.883TrpVal: 0.883 ± 0.008	0.258TrpTrp: 0.258 ± 0.006	0.347TrpTyr: 0.347 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.711TyrAla: 1.711 ± 0.013	0.641TyrCys: 0.641 ± 0.008	1.515TyrAsp: 1.515 ± 0.012	1.52TyrGlu: 1.52 ± 0.012	1.316TyrPhe: 1.316 ± 0.012	2.082TyrGly: 2.082 ± 0.015	0.703TyrHis: 0.703 ± 0.009	1.419TyrIle: 1.419 ± 0.013	1.516TyrLys: 1.516 ± 0.014	2.793TyrLeu: 2.793 ± 0.019	0.7TyrMet: 0.7 ± 0.008	1.332TyrAsn: 1.332 ± 0.01	1.23TyrPro: 1.23 ± 0.011	0.9TyrGln: 0.9 ± 0.008	1.452TyrArg: 1.452 ± 0.012	2.329TyrSer: 2.329 ± 0.015	1.238TyrThr: 1.238 ± 0.011	1.802TyrVal: 1.802 ± 0.013	0.42TyrTrp: 0.42 ± 0.007	1.022TyrTyr: 1.022 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.002XaaSer: 0.002 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.119XaaXaa: 0.119 ± 0.027

Statistics based on 35801 proteins (11250880 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---