Amino acid dipepetide frequency for Byssochlamys spectabilis (strain No. 5 / NBRC 109023) (Paecilomyces variotii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.913AlaAla: 8.913 ± 0.07
0.958AlaCys: 0.958 ± 0.014
4.25AlaAsp: 4.25 ± 0.032
5.166AlaGlu: 5.166 ± 0.042
3.078AlaPhe: 3.078 ± 0.03
5.807AlaGly: 5.807 ± 0.045
1.719AlaHis: 1.719 ± 0.017
4.227AlaIle: 4.227 ± 0.036
3.998AlaLys: 3.998 ± 0.034
7.55AlaLeu: 7.55 ± 0.052
1.871AlaMet: 1.871 ± 0.019
2.869AlaAsn: 2.869 ± 0.028
4.684AlaPro: 4.684 ± 0.042
3.336AlaGln: 3.336 ± 0.031
4.856AlaArg: 4.856 ± 0.033
7.333AlaSer: 7.333 ± 0.057
4.993AlaThr: 4.993 ± 0.035
5.443AlaVal: 5.443 ± 0.04
1.11AlaTrp: 1.11 ± 0.017
2.163AlaTyr: 2.163 ± 0.023
0.0AlaXaa: 0.0 ± 0.0
Cys
0.875CysAla: 0.875 ± 0.016
0.22CysCys: 0.22 ± 0.009
0.604CysAsp: 0.604 ± 0.011
0.564CysGlu: 0.564 ± 0.011
0.529CysPhe: 0.529 ± 0.01
0.866CysGly: 0.866 ± 0.014
0.307CysHis: 0.307 ± 0.008
0.668CysIle: 0.668 ± 0.012
0.471CysLys: 0.471 ± 0.01
1.194CysLeu: 1.194 ± 0.019
0.243CysMet: 0.243 ± 0.007
0.38CysAsn: 0.38 ± 0.01
0.619CysPro: 0.619 ± 0.013
0.412CysGln: 0.412 ± 0.01
0.705CysArg: 0.705 ± 0.013
0.861CysSer: 0.861 ± 0.014
0.616CysThr: 0.616 ± 0.012
0.737CysVal: 0.737 ± 0.015
0.195CysTrp: 0.195 ± 0.007
0.338CysTyr: 0.338 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
4.621AspAla: 4.621 ± 0.033
0.58AspCys: 0.58 ± 0.013
4.088AspAsp: 4.088 ± 0.044
4.578AspGlu: 4.578 ± 0.039
2.201AspPhe: 2.201 ± 0.023
4.048AspGly: 4.048 ± 0.029
1.221AspHis: 1.221 ± 0.016
3.288AspIle: 3.288 ± 0.026
2.384AspLys: 2.384 ± 0.026
5.111AspLeu: 5.111 ± 0.037
1.251AspMet: 1.251 ± 0.018
1.948AspAsn: 1.948 ± 0.02
3.456AspPro: 3.456 ± 0.028
1.871AspGln: 1.871 ± 0.021
3.145AspArg: 3.145 ± 0.028
4.244AspSer: 4.244 ± 0.034
2.993AspThr: 2.993 ± 0.027
3.744AspVal: 3.744 ± 0.03
0.859AspTrp: 0.859 ± 0.014
1.653AspTyr: 1.653 ± 0.019
0.0AspXaa: 0.0 ± 0.0
Glu
5.256GluAla: 5.256 ± 0.04
0.575GluCys: 0.575 ± 0.012
4.318GluAsp: 4.318 ± 0.043
5.805GluGlu: 5.805 ± 0.058
2.005GluPhe: 2.005 ± 0.023
3.75GluGly: 3.75 ± 0.03
1.387GluHis: 1.387 ± 0.018
3.245GluIle: 3.245 ± 0.032
4.012GluLys: 4.012 ± 0.037
5.245GluLeu: 5.245 ± 0.037
1.432GluMet: 1.432 ± 0.017
2.481GluAsn: 2.481 ± 0.024
2.847GluPro: 2.847 ± 0.031
2.609GluGln: 2.609 ± 0.028
4.102GluArg: 4.102 ± 0.038
4.552GluSer: 4.552 ± 0.037
3.7GluThr: 3.7 ± 0.029
3.477GluVal: 3.477 ± 0.029
0.875GluTrp: 0.875 ± 0.014
1.746GluTyr: 1.746 ± 0.02
0.0GluXaa: 0.0 ± 0.0
Phe
2.969PheAla: 2.969 ± 0.027
0.552PheCys: 0.552 ± 0.011
2.299PheAsp: 2.299 ± 0.025
2.151PheGlu: 2.151 ± 0.02
1.653PhePhe: 1.653 ± 0.025
2.812PheGly: 2.812 ± 0.03
0.925PheHis: 0.925 ± 0.014
1.894PheIle: 1.894 ± 0.024
1.441PheLys: 1.441 ± 0.017
3.588PheLeu: 3.588 ± 0.035
0.775PheMet: 0.775 ± 0.013
1.399PheAsn: 1.399 ± 0.018
2.048PhePro: 2.048 ± 0.021
1.402PheGln: 1.402 ± 0.019
1.978PheArg: 1.978 ± 0.021
3.142PheSer: 3.142 ± 0.033
2.108PheThr: 2.108 ± 0.021
2.397PheVal: 2.397 ± 0.026
0.643PheTrp: 0.643 ± 0.014
1.17PheTyr: 1.17 ± 0.017
0.0PheXaa: 0.0 ± 0.0
Gly
5.316GlyAla: 5.316 ± 0.042
0.8GlyCys: 0.8 ± 0.015
3.636GlyAsp: 3.636 ± 0.028
3.674GlyGlu: 3.674 ± 0.028
2.821GlyPhe: 2.821 ± 0.027
5.438GlyGly: 5.438 ± 0.053
1.697GlyHis: 1.697 ± 0.021
3.621GlyIle: 3.621 ± 0.033
3.503GlyLys: 3.503 ± 0.029
6.083GlyLeu: 6.083 ± 0.044
1.489GlyMet: 1.489 ± 0.018
2.536GlyAsn: 2.536 ± 0.029
3.435GlyPro: 3.435 ± 0.035
2.57GlyGln: 2.57 ± 0.028
4.121GlyArg: 4.121 ± 0.038
5.947GlySer: 5.947 ± 0.046
3.926GlyThr: 3.926 ± 0.033
4.367GlyVal: 4.367 ± 0.039
1.137GlyTrp: 1.137 ± 0.017
2.179GlyTyr: 2.179 ± 0.023
0.0GlyXaa: 0.0 ± 0.0
His
1.774HisAla: 1.774 ± 0.018
0.311HisCys: 0.311 ± 0.008
1.279HisAsp: 1.279 ± 0.018
1.364HisGlu: 1.364 ± 0.018
0.911HisPhe: 0.911 ± 0.014
1.706HisGly: 1.706 ± 0.019
0.799HisHis: 0.799 ± 0.018
1.257HisIle: 1.257 ± 0.017
0.868HisLys: 0.868 ± 0.014
2.206HisLeu: 2.206 ± 0.026
0.475HisMet: 0.475 ± 0.011
0.815HisAsn: 0.815 ± 0.013
1.637HisPro: 1.637 ± 0.02
0.897HisGln: 0.897 ± 0.014
1.577HisArg: 1.577 ± 0.023
1.787HisSer: 1.787 ± 0.02
1.191HisThr: 1.191 ± 0.016
1.448HisVal: 1.448 ± 0.017
0.351HisTrp: 0.351 ± 0.009
0.696HisTyr: 0.696 ± 0.011
0.0HisXaa: 0.0 ± 0.0
Ile
4.155IleAla: 4.155 ± 0.032
0.755IleCys: 0.755 ± 0.014
2.94IleAsp: 2.94 ± 0.026
2.956IleGlu: 2.956 ± 0.024
2.076IlePhe: 2.076 ± 0.024
3.26IleGly: 3.26 ± 0.036
1.245IleHis: 1.245 ± 0.015
2.64IleIle: 2.64 ± 0.03
2.187IleLys: 2.187 ± 0.024
4.705IleLeu: 4.705 ± 0.047
1.006IleMet: 1.006 ± 0.016
1.803IleAsn: 1.803 ± 0.019
3.253IlePro: 3.253 ± 0.027
1.903IleGln: 1.903 ± 0.022
2.899IleArg: 2.899 ± 0.027
4.129IleSer: 4.129 ± 0.032
2.794IleThr: 2.794 ± 0.026
3.252IleVal: 3.252 ± 0.03
0.731IleTrp: 0.731 ± 0.016
1.503IleTyr: 1.503 ± 0.018
0.0IleXaa: 0.0 ± 0.0
Lys
4.17LysAla: 4.17 ± 0.034
0.447LysCys: 0.447 ± 0.01
2.893LysAsp: 2.893 ± 0.028
3.661LysGlu: 3.661 ± 0.035
1.42LysPhe: 1.42 ± 0.018
3.036LysGly: 3.036 ± 0.029
1.073LysHis: 1.073 ± 0.015
2.314LysIle: 2.314 ± 0.023
3.397LysLys: 3.397 ± 0.043
4.059LysLeu: 4.059 ± 0.032
0.97LysMet: 0.97 ± 0.016
1.765LysAsn: 1.765 ± 0.019
2.683LysPro: 2.683 ± 0.032
1.897LysGln: 1.897 ± 0.021
3.468LysArg: 3.468 ± 0.034
3.557LysSer: 3.557 ± 0.035
2.822LysThr: 2.822 ± 0.026
2.83LysVal: 2.83 ± 0.026
0.649LysTrp: 0.649 ± 0.013
1.408LysTyr: 1.408 ± 0.019
0.0LysXaa: 0.0 ± 0.0
Leu
7.493LeuAla: 7.493 ± 0.05
1.149LeuCys: 1.149 ± 0.017
5.195LeuAsp: 5.195 ± 0.037
5.533LeuGlu: 5.533 ± 0.04
3.408LeuPhe: 3.408 ± 0.038
5.856LeuGly: 5.856 ± 0.043
2.183LeuHis: 2.183 ± 0.023
4.025LeuIle: 4.025 ± 0.035
4.242LeuLys: 4.242 ± 0.036
8.412LeuLeu: 8.412 ± 0.074
1.74LeuMet: 1.74 ± 0.017
3.161LeuAsn: 3.161 ± 0.027
5.449LeuPro: 5.449 ± 0.035
3.812LeuGln: 3.812 ± 0.031
5.912LeuArg: 5.912 ± 0.039
7.702LeuSer: 7.702 ± 0.051
4.739LeuThr: 4.739 ± 0.037
5.327LeuVal: 5.327 ± 0.039
1.185LeuTrp: 1.185 ± 0.017
2.47LeuTyr: 2.47 ± 0.024
0.0LeuXaa: 0.0 ± 0.0
Met
2.166MetAla: 2.166 ± 0.02
0.228MetCys: 0.228 ± 0.008
1.237MetAsp: 1.237 ± 0.017
1.284MetGlu: 1.284 ± 0.019
0.741MetPhe: 0.741 ± 0.013
1.447MetGly: 1.447 ± 0.02
0.453MetHis: 0.453 ± 0.009
0.985MetIle: 0.985 ± 0.015
0.989MetLys: 0.989 ± 0.015
1.754MetLeu: 1.754 ± 0.019
0.526MetMet: 0.526 ± 0.011
0.77MetAsn: 0.77 ± 0.015
1.158MetPro: 1.158 ± 0.015
0.823MetGln: 0.823 ± 0.016
1.228MetArg: 1.228 ± 0.016
1.816MetSer: 1.816 ± 0.02
1.254MetThr: 1.254 ± 0.014
1.244MetVal: 1.244 ± 0.016
0.249MetTrp: 0.249 ± 0.007
0.49MetTyr: 0.49 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
3.117AsnAla: 3.117 ± 0.029
0.423AsnCys: 0.423 ± 0.01
1.994AsnAsp: 1.994 ± 0.022
2.125AsnGlu: 2.125 ± 0.021
1.344AsnPhe: 1.344 ± 0.017
3.048AsnGly: 3.048 ± 0.029
0.803AsnHis: 0.803 ± 0.013
2.086AsnIle: 2.086 ± 0.018
1.548AsnLys: 1.548 ± 0.019
3.172AsnLeu: 3.172 ± 0.029
0.816AsnMet: 0.816 ± 0.013
1.454AsnAsn: 1.454 ± 0.024
2.462AsnPro: 2.462 ± 0.024
1.299AsnGln: 1.299 ± 0.018
2.023AsnArg: 2.023 ± 0.021
2.761AsnSer: 2.761 ± 0.029
2.103AsnThr: 2.103 ± 0.024
2.366AsnVal: 2.366 ± 0.024
0.542AsnTrp: 0.542 ± 0.011
1.078AsnTyr: 1.078 ± 0.017
0.0AsnXaa: 0.0 ± 0.0
Pro
5.19ProAla: 5.19 ± 0.047
0.465ProCys: 0.465 ± 0.011
3.339ProAsp: 3.339 ± 0.03
4.104ProGlu: 4.104 ± 0.037
2.126ProPhe: 2.126 ± 0.023
4.037ProGly: 4.037 ± 0.035
1.291ProHis: 1.291 ± 0.019
2.52ProIle: 2.52 ± 0.025
2.618ProLys: 2.618 ± 0.025
4.771ProLeu: 4.771 ± 0.039
1.034ProMet: 1.034 ± 0.018
2.129ProAsn: 2.129 ± 0.025
4.973ProPro: 4.973 ± 0.067
2.481ProGln: 2.481 ± 0.034
3.484ProArg: 3.484 ± 0.032
6.247ProSer: 6.247 ± 0.052
3.746ProThr: 3.746 ± 0.034
3.759ProVal: 3.759 ± 0.035
0.758ProTrp: 0.758 ± 0.013
1.599ProTyr: 1.599 ± 0.02
0.0ProXaa: 0.0 ± 0.0
Gln
3.249GlnAla: 3.249 ± 0.028
0.407GlnCys: 0.407 ± 0.01
2.035GlnAsp: 2.035 ± 0.023
2.539GlnGlu: 2.539 ± 0.027
1.292GlnPhe: 1.292 ± 0.016
2.389GlnGly: 2.389 ± 0.023
1.01GlnHis: 1.01 ± 0.017
1.883GlnIle: 1.883 ± 0.02
2.119GlnLys: 2.119 ± 0.021
3.423GlnLeu: 3.423 ± 0.032
0.867GlnMet: 0.867 ± 0.014
1.641GlnAsn: 1.641 ± 0.019
2.469GlnPro: 2.469 ± 0.029
2.329GlnGln: 2.329 ± 0.039
2.716GlnArg: 2.716 ± 0.029
3.226GlnSer: 3.226 ± 0.028
2.307GlnThr: 2.307 ± 0.022
2.071GlnVal: 2.071 ± 0.022
0.544GlnTrp: 0.544 ± 0.011
1.153GlnTyr: 1.153 ± 0.015
0.0GlnXaa: 0.0 ± 0.0
Arg
4.676ArgAla: 4.676 ± 0.035
0.668ArgCys: 0.668 ± 0.013
3.426ArgAsp: 3.426 ± 0.036
4.044ArgGlu: 4.044 ± 0.038
2.224ArgPhe: 2.224 ± 0.022
3.765ArgGly: 3.765 ± 0.034
1.528ArgHis: 1.528 ± 0.02
2.959ArgIle: 2.959 ± 0.028
3.495ArgLys: 3.495 ± 0.029
5.55ArgLeu: 5.55 ± 0.042
1.266ArgMet: 1.266 ± 0.018
2.343ArgAsn: 2.343 ± 0.025
3.635ArgPro: 3.635 ± 0.035
2.649ArgGln: 2.649 ± 0.025
5.271ArgArg: 5.271 ± 0.049
5.041ArgSer: 5.041 ± 0.042
3.326ArgThr: 3.326 ± 0.032
3.422ArgVal: 3.422 ± 0.028
0.95ArgTrp: 0.95 ± 0.014
1.753ArgTyr: 1.753 ± 0.02
0.0ArgXaa: 0.0 ± 0.0
Ser
6.891SerAla: 6.891 ± 0.053
0.829SerCys: 0.829 ± 0.015
4.435SerAsp: 4.435 ± 0.033
4.351SerGlu: 4.351 ± 0.032
3.127SerPhe: 3.127 ± 0.031
5.727SerGly: 5.727 ± 0.048
1.981SerHis: 1.981 ± 0.021
4.108SerIle: 4.108 ± 0.03
3.85SerLys: 3.85 ± 0.034
7.495SerLeu: 7.495 ± 0.041
1.681SerMet: 1.681 ± 0.02
3.055SerAsn: 3.055 ± 0.028
5.694SerPro: 5.694 ± 0.059
3.388SerGln: 3.388 ± 0.031
5.332SerArg: 5.332 ± 0.049
9.406SerSer: 9.406 ± 0.084
5.628SerThr: 5.628 ± 0.048
4.799SerVal: 4.799 ± 0.031
1.132SerTrp: 1.132 ± 0.015
2.122SerTyr: 2.122 ± 0.024
0.0SerXaa: 0.0 ± 0.0
Thr
5.243ThrAla: 5.243 ± 0.04
0.689ThrCys: 0.689 ± 0.014
2.919ThrAsp: 2.919 ± 0.028
3.222ThrGlu: 3.222 ± 0.026
2.202ThrPhe: 2.202 ± 0.02
4.241ThrGly: 4.241 ± 0.033
1.2ThrHis: 1.2 ± 0.017
3.057ThrIle: 3.057 ± 0.03
2.59ThrLys: 2.59 ± 0.027
5.022ThrLeu: 5.022 ± 0.037
1.139ThrMet: 1.139 ± 0.014
1.98ThrAsn: 1.98 ± 0.018
4.222ThrPro: 4.222 ± 0.042
1.971ThrGln: 1.971 ± 0.023
3.081ThrArg: 3.081 ± 0.027
5.168ThrSer: 5.168 ± 0.04
3.968ThrThr: 3.968 ± 0.037
3.89ThrVal: 3.89 ± 0.034
0.798ThrTrp: 0.798 ± 0.012
1.629ThrTyr: 1.629 ± 0.02
0.0ThrXaa: 0.0 ± 0.0
Val
5.045ValAla: 5.045 ± 0.043
0.784ValCys: 0.784 ± 0.012
3.808ValAsp: 3.808 ± 0.031
3.847ValGlu: 3.847 ± 0.032
2.429ValPhe: 2.429 ± 0.028
3.969ValGly: 3.969 ± 0.033
1.417ValHis: 1.417 ± 0.018
3.124ValIle: 3.124 ± 0.03
2.875ValLys: 2.875 ± 0.027
5.612ValLeu: 5.612 ± 0.045
1.261ValMet: 1.261 ± 0.017
2.267ValAsn: 2.267 ± 0.022
3.767ValPro: 3.767 ± 0.032
2.374ValGln: 2.374 ± 0.021
3.457ValArg: 3.457 ± 0.029
4.931ValSer: 4.931 ± 0.043
3.55ValThr: 3.55 ± 0.032
4.226ValVal: 4.226 ± 0.036
0.822ValTrp: 0.822 ± 0.013
1.757ValTyr: 1.757 ± 0.018
0.0ValXaa: 0.0 ± 0.0
Trp
1.051TrpAla: 1.051 ± 0.016
0.179TrpCys: 0.179 ± 0.006
0.892TrpAsp: 0.892 ± 0.015
0.856TrpGlu: 0.856 ± 0.015
0.534TrpPhe: 0.534 ± 0.011
0.9TrpGly: 0.9 ± 0.015
0.346TrpHis: 0.346 ± 0.009
0.792TrpIle: 0.792 ± 0.014
0.834TrpLys: 0.834 ± 0.015
1.322TrpLeu: 1.322 ± 0.018
0.366TrpMet: 0.366 ± 0.008
0.635TrpAsn: 0.635 ± 0.012
0.582TrpPro: 0.582 ± 0.011
0.539TrpGln: 0.539 ± 0.009
0.952TrpArg: 0.952 ± 0.015
1.037TrpSer: 1.037 ± 0.015
0.891TrpThr: 0.891 ± 0.014
0.825TrpVal: 0.825 ± 0.013
0.275TrpTrp: 0.275 ± 0.009
0.437TrpTyr: 0.437 ± 0.011
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.155TyrAla: 2.155 ± 0.023
0.388TyrCys: 0.388 ± 0.009
1.699TyrAsp: 1.699 ± 0.018
1.594TyrGlu: 1.594 ± 0.02
1.225TyrPhe: 1.225 ± 0.015
2.197TyrGly: 2.197 ± 0.027
0.766TyrHis: 0.766 ± 0.015
1.497TyrIle: 1.497 ± 0.016
1.098TyrLys: 1.098 ± 0.014
2.72TyrLeu: 2.72 ± 0.023
0.632TyrMet: 0.632 ± 0.011
1.131TyrAsn: 1.131 ± 0.015
1.593TyrPro: 1.593 ± 0.018
1.102TyrGln: 1.102 ± 0.018
1.687TyrArg: 1.687 ± 0.02
2.144TyrSer: 2.144 ± 0.021
1.577TyrThr: 1.577 ± 0.02
1.696TyrVal: 1.696 ± 0.021
0.44TyrTrp: 0.44 ± 0.01
0.968TyrTyr: 0.968 ± 0.016
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8877 proteins (4775538 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski