Amino acid dipepetide frequency for Ustilaginoidea virens (Rice false smut fungus) (Villosiclava virens)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.099AlaAla: 13.099 ± 0.119	1.29AlaCys: 1.29 ± 0.019	5.173AlaAsp: 5.173 ± 0.044	5.625AlaGlu: 5.625 ± 0.058	3.016AlaPhe: 3.016 ± 0.034	7.095AlaGly: 7.095 ± 0.059	2.136AlaHis: 2.136 ± 0.024	3.724AlaIle: 3.724 ± 0.034	4.388AlaLys: 4.388 ± 0.041	8.26AlaLeu: 8.26 ± 0.057	2.124AlaMet: 2.124 ± 0.021	2.99AlaAsn: 2.99 ± 0.026	5.618AlaPro: 5.618 ± 0.056	3.863AlaGln: 3.863 ± 0.038	6.425AlaArg: 6.425 ± 0.051	8.637AlaSer: 8.637 ± 0.056	5.568AlaThr: 5.568 ± 0.049	6.254AlaVal: 6.254 ± 0.051	1.23AlaTrp: 1.23 ± 0.019	2.037AlaTyr: 2.037 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	1.118CysAla: 1.118 ± 0.019	0.289CysCys: 0.289 ± 0.011	0.698CysAsp: 0.698 ± 0.014	0.603CysGlu: 0.603 ± 0.012	0.526CysPhe: 0.526 ± 0.011	1.022CysGly: 1.022 ± 0.023	0.373CysHis: 0.373 ± 0.011	0.594CysIle: 0.594 ± 0.016	0.527CysLys: 0.527 ± 0.012	1.364CysLeu: 1.364 ± 0.021	0.29CysMet: 0.29 ± 0.008	0.456CysAsn: 0.456 ± 0.013	0.805CysPro: 0.805 ± 0.016	0.511CysGln: 0.511 ± 0.013	0.999CysArg: 0.999 ± 0.018	1.029CysSer: 1.029 ± 0.018	0.663CysThr: 0.663 ± 0.015	0.86CysVal: 0.86 ± 0.015	0.211CysTrp: 0.211 ± 0.008	0.331CysTyr: 0.331 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.072AspAla: 6.072 ± 0.058	0.686AspCys: 0.686 ± 0.013	5.251AspAsp: 5.251 ± 0.074	4.647AspGlu: 4.647 ± 0.05	2.115AspPhe: 2.115 ± 0.023	4.919AspGly: 4.919 ± 0.047	1.256AspHis: 1.256 ± 0.018	2.428AspIle: 2.428 ± 0.027	2.561AspLys: 2.561 ± 0.034	4.799AspLeu: 4.799 ± 0.041	1.399AspMet: 1.399 ± 0.02	1.668AspAsn: 1.668 ± 0.022	3.059AspPro: 3.059 ± 0.038	1.918AspGln: 1.918 ± 0.022	3.286AspArg: 3.286 ± 0.044	4.049AspSer: 4.049 ± 0.033	2.5AspThr: 2.5 ± 0.025	3.964AspVal: 3.964 ± 0.045	0.818AspTrp: 0.818 ± 0.016	1.419AspTyr: 1.419 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	5.956GluAla: 5.956 ± 0.055	0.591GluCys: 0.591 ± 0.012	3.868GluAsp: 3.868 ± 0.045	4.868GluGlu: 4.868 ± 0.064	1.729GluPhe: 1.729 ± 0.023	3.382GluGly: 3.382 ± 0.035	1.417GluHis: 1.417 ± 0.02	2.386GluIle: 2.386 ± 0.026	3.142GluLys: 3.142 ± 0.035	5.058GluLeu: 5.058 ± 0.045	1.396GluMet: 1.396 ± 0.019	1.887GluAsn: 1.887 ± 0.025	2.992GluPro: 2.992 ± 0.04	2.573GluGln: 2.573 ± 0.03	3.968GluArg: 3.968 ± 0.036	4.008GluSer: 4.008 ± 0.036	3.226GluThr: 3.226 ± 0.043	3.138GluVal: 3.138 ± 0.032	0.796GluTrp: 0.796 ± 0.016	1.428GluTyr: 1.428 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.092PheAla: 3.092 ± 0.031	0.552PheCys: 0.552 ± 0.012	2.105PheAsp: 2.105 ± 0.029	1.875PheGlu: 1.875 ± 0.023	1.436PhePhe: 1.436 ± 0.024	2.606PheGly: 2.606 ± 0.035	0.855PheHis: 0.855 ± 0.017	1.4PheIle: 1.4 ± 0.023	1.356PheLys: 1.356 ± 0.018	3.13PheLeu: 3.13 ± 0.037	0.692PheMet: 0.692 ± 0.014	1.177PheAsn: 1.177 ± 0.019	1.799PhePro: 1.799 ± 0.022	1.271PheGln: 1.271 ± 0.02	2.018PheArg: 2.018 ± 0.025	2.714PheSer: 2.714 ± 0.031	1.77PheThr: 1.77 ± 0.022	2.292PheVal: 2.292 ± 0.028	0.553PheTrp: 0.553 ± 0.012	0.92PheTyr: 0.92 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	6.208GlyAla: 6.208 ± 0.05	0.969GlyCys: 0.969 ± 0.016	4.005GlyAsp: 4.005 ± 0.034	3.697GlyGlu: 3.697 ± 0.039	2.607GlyPhe: 2.607 ± 0.031	6.826GlyGly: 6.826 ± 0.076	1.882GlyHis: 1.882 ± 0.026	3.07GlyIle: 3.07 ± 0.035	3.466GlyLys: 3.466 ± 0.032	6.203GlyLeu: 6.203 ± 0.048	1.591GlyMet: 1.591 ± 0.025	2.522GlyAsn: 2.522 ± 0.031	3.829GlyPro: 3.829 ± 0.039	2.914GlyGln: 2.914 ± 0.034	5.118GlyArg: 5.118 ± 0.044	6.295GlySer: 6.295 ± 0.061	4.06GlyThr: 4.06 ± 0.108	4.346GlyVal: 4.346 ± 0.039	1.154GlyTrp: 1.154 ± 0.024	1.876GlyTyr: 1.876 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.225HisAla: 2.225 ± 0.023	0.344HisCys: 0.344 ± 0.008	1.537HisAsp: 1.537 ± 0.023	1.318HisGlu: 1.318 ± 0.02	0.841HisPhe: 0.841 ± 0.016	2.094HisGly: 2.094 ± 0.029	1.139HisHis: 1.139 ± 0.032	0.975HisIle: 0.975 ± 0.017	0.889HisLys: 0.889 ± 0.018	2.317HisLeu: 2.317 ± 0.027	0.511HisMet: 0.511 ± 0.012	0.715HisAsn: 0.715 ± 0.014	1.75HisPro: 1.75 ± 0.027	1.22HisGln: 1.22 ± 0.026	1.755HisArg: 1.755 ± 0.022	1.767HisSer: 1.767 ± 0.024	1.031HisThr: 1.031 ± 0.018	1.745HisVal: 1.745 ± 0.022	0.288HisTrp: 0.288 ± 0.009	0.625HisTyr: 0.625 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.549IleAla: 3.549 ± 0.033	0.643IleCys: 0.643 ± 0.014	2.381IleAsp: 2.381 ± 0.029	2.19IleGlu: 2.19 ± 0.025	1.505IlePhe: 1.505 ± 0.025	2.593IleGly: 2.593 ± 0.032	1.037IleHis: 1.037 ± 0.016	1.939IleIle: 1.939 ± 0.035	1.866IleLys: 1.866 ± 0.025	3.886IleLeu: 3.886 ± 0.034	0.886IleMet: 0.886 ± 0.016	1.405IleAsn: 1.405 ± 0.019	2.602IlePro: 2.602 ± 0.036	1.625IleGln: 1.625 ± 0.029	2.635IleArg: 2.635 ± 0.029	3.13IleSer: 3.13 ± 0.037	2.306IleThr: 2.306 ± 0.045	2.716IleVal: 2.716 ± 0.03	0.569IleTrp: 0.569 ± 0.013	1.059IleTyr: 1.059 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.329LysAla: 4.329 ± 0.043	0.476LysCys: 0.476 ± 0.011	2.615LysAsp: 2.615 ± 0.032	2.851LysGlu: 2.851 ± 0.035	1.31LysPhe: 1.31 ± 0.021	2.776LysGly: 2.776 ± 0.03	1.154LysHis: 1.154 ± 0.019	1.886LysIle: 1.886 ± 0.021	4.04LysLys: 4.04 ± 0.213	3.979LysLeu: 3.979 ± 0.041	1.014LysMet: 1.014 ± 0.017	1.489LysAsn: 1.489 ± 0.022	2.759LysPro: 2.759 ± 0.032	1.898LysGln: 1.898 ± 0.025	3.506LysArg: 3.506 ± 0.039	3.274LysSer: 3.274 ± 0.032	2.674LysThr: 2.674 ± 0.025	2.597LysVal: 2.597 ± 0.033	0.572LysTrp: 0.572 ± 0.013	1.148LysTyr: 1.148 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	8.776LeuAla: 8.776 ± 0.06	1.258LeuCys: 1.258 ± 0.022	5.338LeuAsp: 5.338 ± 0.043	5.175LeuGlu: 5.175 ± 0.046	3.059LeuPhe: 3.059 ± 0.032	6.274LeuGly: 6.274 ± 0.051	2.217LeuHis: 2.217 ± 0.028	3.194LeuIle: 3.194 ± 0.04	3.774LeuLys: 3.774 ± 0.038	8.341LeuLeu: 8.341 ± 0.079	1.748LeuMet: 1.748 ± 0.024	2.693LeuAsn: 2.693 ± 0.033	5.684LeuPro: 5.684 ± 0.047	3.847LeuGln: 3.847 ± 0.041	6.295LeuArg: 6.295 ± 0.041	7.023LeuSer: 7.023 ± 0.051	4.429LeuThr: 4.429 ± 0.045	5.767LeuVal: 5.767 ± 0.045	1.126LeuTrp: 1.126 ± 0.018	2.044LeuTyr: 2.044 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.414MetAla: 2.414 ± 0.025	0.242MetCys: 0.242 ± 0.008	1.272MetAsp: 1.272 ± 0.019	1.237MetGlu: 1.237 ± 0.017	0.661MetPhe: 0.661 ± 0.014	1.457MetGly: 1.457 ± 0.023	0.487MetHis: 0.487 ± 0.01	0.823MetIle: 0.823 ± 0.015	0.923MetLys: 0.923 ± 0.015	1.862MetLeu: 1.862 ± 0.024	0.596MetMet: 0.596 ± 0.014	0.697MetAsn: 0.697 ± 0.016	1.38MetPro: 1.38 ± 0.02	0.893MetGln: 0.893 ± 0.019	1.358MetArg: 1.358 ± 0.019	1.801MetSer: 1.801 ± 0.022	1.29MetThr: 1.29 ± 0.018	1.29MetVal: 1.29 ± 0.019	0.248MetTrp: 0.248 ± 0.007	0.5MetTyr: 0.5 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.922AsnAla: 2.922 ± 0.032	0.43AsnCys: 0.43 ± 0.015	1.795AsnAsp: 1.795 ± 0.022	1.652AsnGlu: 1.652 ± 0.023	1.116AsnPhe: 1.116 ± 0.018	2.725AsnGly: 2.725 ± 0.036	0.816AsnHis: 0.816 ± 0.016	1.513AsnIle: 1.513 ± 0.018	1.412AsnLys: 1.412 ± 0.02	2.949AsnLeu: 2.949 ± 0.031	0.78AsnMet: 0.78 ± 0.015	1.284AsnAsn: 1.284 ± 0.027	2.286AsnPro: 2.286 ± 0.026	1.274AsnGln: 1.274 ± 0.02	1.935AsnArg: 1.935 ± 0.024	2.444AsnSer: 2.444 ± 0.03	1.665AsnThr: 1.665 ± 0.023	2.134AsnVal: 2.134 ± 0.024	0.444AsnTrp: 0.444 ± 0.011	0.847AsnTyr: 0.847 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	6.668ProAla: 6.668 ± 0.068	0.728ProCys: 0.728 ± 0.015	3.409ProAsp: 3.409 ± 0.032	3.436ProGlu: 3.436 ± 0.041	1.919ProPhe: 1.919 ± 0.025	4.676ProGly: 4.676 ± 0.045	1.434ProHis: 1.434 ± 0.025	2.049ProIle: 2.049 ± 0.023	2.434ProLys: 2.434 ± 0.029	4.85ProLeu: 4.85 ± 0.037	1.044ProMet: 1.044 ± 0.016	1.903ProAsn: 1.903 ± 0.025	6.277ProPro: 6.277 ± 0.108	2.537ProGln: 2.537 ± 0.036	4.279ProArg: 4.279 ± 0.046	6.366ProSer: 6.366 ± 0.063	3.775ProThr: 3.775 ± 0.056	3.76ProVal: 3.76 ± 0.035	0.755ProTrp: 0.755 ± 0.014	1.351ProTyr: 1.351 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.981GlnAla: 3.981 ± 0.038	0.435GlnCys: 0.435 ± 0.016	2.334GlnAsp: 2.334 ± 0.027	2.314GlnGlu: 2.314 ± 0.026	1.15GlnPhe: 1.15 ± 0.02	2.681GlnGly: 2.681 ± 0.028	1.328GlnHis: 1.328 ± 0.026	1.575GlnIle: 1.575 ± 0.018	1.832GlnLys: 1.832 ± 0.025	3.623GlnLeu: 3.623 ± 0.035	0.889GlnMet: 0.889 ± 0.019	1.31GlnAsn: 1.31 ± 0.021	2.966GlnPro: 2.966 ± 0.042	3.316GlnGln: 3.316 ± 0.093	2.994GlnArg: 2.994 ± 0.031	3.042GlnSer: 3.042 ± 0.036	2.216GlnThr: 2.216 ± 0.032	2.376GlnVal: 2.376 ± 0.026	0.501GlnTrp: 0.501 ± 0.012	1.011GlnTyr: 1.011 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	5.978ArgAla: 5.978 ± 0.045	0.917ArgCys: 0.917 ± 0.019	3.995ArgAsp: 3.995 ± 0.048	4.011ArgGlu: 4.011 ± 0.04	2.205ArgPhe: 2.205 ± 0.022	4.576ArgGly: 4.576 ± 0.045	1.983ArgHis: 1.983 ± 0.023	2.839ArgIle: 2.839 ± 0.026	3.512ArgLys: 3.512 ± 0.038	6.217ArgLeu: 6.217 ± 0.046	1.39ArgMet: 1.39 ± 0.018	2.277ArgAsn: 2.277 ± 0.027	4.279ArgPro: 4.279 ± 0.06	3.175ArgGln: 3.175 ± 0.035	6.62ArgArg: 6.62 ± 0.074	5.2ArgSer: 5.2 ± 0.039	3.323ArgThr: 3.323 ± 0.035	3.794ArgVal: 3.794 ± 0.035	0.957ArgTrp: 0.957 ± 0.017	1.57ArgTyr: 1.57 ± 0.023	0.0ArgXaa: 0.0 ± 0.0
Ser	7.458SerAla: 7.458 ± 0.059	1.098SerCys: 1.098 ± 0.019	4.155SerAsp: 4.155 ± 0.051	3.803SerGlu: 3.803 ± 0.035	2.767SerPhe: 2.767 ± 0.029	5.838SerGly: 5.838 ± 0.061	2.004SerHis: 2.004 ± 0.029	3.363SerIle: 3.363 ± 0.035	3.531SerLys: 3.531 ± 0.038	7.238SerLeu: 7.238 ± 0.054	1.689SerMet: 1.689 ± 0.023	2.678SerAsn: 2.678 ± 0.029	5.837SerPro: 5.837 ± 0.055	3.263SerGln: 3.263 ± 0.037	5.907SerArg: 5.907 ± 0.044	9.151SerSer: 9.151 ± 0.087	4.962SerThr: 4.962 ± 0.046	4.647SerVal: 4.647 ± 0.045	1.087SerTrp: 1.087 ± 0.02	1.802SerTyr: 1.802 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.402ThrAla: 5.402 ± 0.047	0.835ThrCys: 0.835 ± 0.015	2.549ThrAsp: 2.549 ± 0.029	2.651ThrGlu: 2.651 ± 0.034	1.859ThrPhe: 1.859 ± 0.024	3.982ThrGly: 3.982 ± 0.046	1.166ThrHis: 1.166 ± 0.018	2.52ThrIle: 2.52 ± 0.053	2.256ThrLys: 2.256 ± 0.026	4.744ThrLeu: 4.744 ± 0.037	1.152ThrMet: 1.152 ± 0.021	1.799ThrAsn: 1.799 ± 0.032	4.061ThrPro: 4.061 ± 0.042	1.928ThrGln: 1.928 ± 0.028	3.323ThrArg: 3.323 ± 0.03	4.896ThrSer: 4.896 ± 0.06	3.88ThrThr: 3.88 ± 0.058	3.593ThrVal: 3.593 ± 0.048	0.775ThrTrp: 0.775 ± 0.015	1.452ThrTyr: 1.452 ± 0.095	0.0ThrXaa: 0.0 ± 0.0
Val	6.115ValAla: 6.115 ± 0.047	0.901ValCys: 0.901 ± 0.018	3.99ValAsp: 3.99 ± 0.035	3.793ValGlu: 3.793 ± 0.038	2.348ValPhe: 2.348 ± 0.028	4.298ValGly: 4.298 ± 0.042	1.398ValHis: 1.398 ± 0.018	2.549ValIle: 2.549 ± 0.032	2.766ValLys: 2.766 ± 0.028	5.646ValLeu: 5.646 ± 0.043	1.342ValMet: 1.342 ± 0.021	2.057ValAsn: 2.057 ± 0.026	3.747ValPro: 3.747 ± 0.038	2.33ValGln: 2.33 ± 0.026	3.875ValArg: 3.875 ± 0.049	4.68ValSer: 4.68 ± 0.039	3.413ValThr: 3.413 ± 0.048	4.705ValVal: 4.705 ± 0.056	0.816ValTrp: 0.816 ± 0.017	1.581ValTyr: 1.581 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.141TrpAla: 1.141 ± 0.016	0.197TrpCys: 0.197 ± 0.008	0.861TrpAsp: 0.861 ± 0.021	0.751TrpGlu: 0.751 ± 0.015	0.474TrpPhe: 0.474 ± 0.011	0.843TrpGly: 0.843 ± 0.019	0.358TrpHis: 0.358 ± 0.01	0.623TrpIle: 0.623 ± 0.013	0.693TrpLys: 0.693 ± 0.013	1.295TrpLeu: 1.295 ± 0.022	0.334TrpMet: 0.334 ± 0.009	0.535TrpAsn: 0.535 ± 0.013	0.642TrpPro: 0.642 ± 0.016	0.574TrpGln: 0.574 ± 0.011	0.981TrpArg: 0.981 ± 0.018	0.979TrpSer: 0.979 ± 0.017	0.834TrpThr: 0.834 ± 0.014	0.806TrpVal: 0.806 ± 0.016	0.266TrpTrp: 0.266 ± 0.01	0.339TrpTyr: 0.339 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.048TyrAla: 2.048 ± 0.026	0.387TyrCys: 0.387 ± 0.011	1.489TyrAsp: 1.489 ± 0.021	1.311TyrGlu: 1.311 ± 0.019	0.969TyrPhe: 0.969 ± 0.018	1.974TyrGly: 1.974 ± 0.096	0.645TyrHis: 0.645 ± 0.013	1.071TyrIle: 1.071 ± 0.02	0.978TyrLys: 0.978 ± 0.016	2.302TyrLeu: 2.302 ± 0.03	0.563TyrMet: 0.563 ± 0.012	0.882TyrAsn: 0.882 ± 0.017	1.276TyrPro: 1.276 ± 0.021	0.946TyrGln: 0.946 ± 0.017	1.537TyrArg: 1.537 ± 0.022	1.792TyrSer: 1.792 ± 0.024	1.238TyrThr: 1.238 ± 0.018	1.568TyrVal: 1.568 ± 0.023	0.36TyrTrp: 0.36 ± 0.009	0.765TyrTyr: 0.765 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.01XaaXaa: 0.01 ± 0.01

Statistics based on 8421 proteins (3909507 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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