Human papillomavirus type 161

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 19

Average proteome isoelectric point is 6.13

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|K4MYZ2|K4MYZ2_9PAPI Protein E7 OS=Human papillomavirus type 161 OX=1315264 GN=E7 PE=3 SV=1
MM1 pKa = 6.86YY2 pKa = 10.0RR3 pKa = 11.84AGRR6 pKa = 11.84RR7 pKa = 11.84TRR9 pKa = 11.84ASAEE13 pKa = 3.99DD14 pKa = 4.32LYY16 pKa = 10.9KK17 pKa = 10.62QCFTGDD23 pKa = 3.78CPPDD27 pKa = 3.41VKK29 pKa = 11.18NKK31 pKa = 10.16IEE33 pKa = 4.24GDD35 pKa = 3.2TWADD39 pKa = 3.91RR40 pKa = 11.84LLKK43 pKa = 10.26WFGSVIYY50 pKa = 10.62LGGLGIGTGRR60 pKa = 11.84GSGGSTGYY68 pKa = 10.46RR69 pKa = 11.84PIGGTTRR76 pKa = 11.84PIPDD80 pKa = 4.88TIPVRR85 pKa = 11.84PAVPVEE91 pKa = 3.99PIGPVEE97 pKa = 5.15IIPIDD102 pKa = 3.97TINPAGPSVIDD113 pKa = 3.64LTNVQIPDD121 pKa = 3.62PSIIDD126 pKa = 3.32IANPTTALGPGGIDD140 pKa = 2.56IVSATDD146 pKa = 4.12PIGDD150 pKa = 3.71LGGVGGNPTVITSVDD165 pKa = 3.36DD166 pKa = 3.32TAAILDD172 pKa = 4.04VQPIPPPKK180 pKa = 10.16RR181 pKa = 11.84FALDD185 pKa = 3.26VNNEE189 pKa = 3.85PRR191 pKa = 11.84SGHH194 pKa = 4.01VTVYY198 pKa = 10.95SSTTHH203 pKa = 7.41PDD205 pKa = 2.87PDD207 pKa = 3.43INIFVSPNYY216 pKa = 9.69QGEE219 pKa = 4.23IVGDD223 pKa = 3.73VEE225 pKa = 5.15EE226 pKa = 4.98IPLTTFSEE234 pKa = 4.35MAEE237 pKa = 4.04FEE239 pKa = 4.06IMEE242 pKa = 5.34PGPQTSTPTQIVEE255 pKa = 4.2RR256 pKa = 11.84LAGNARR262 pKa = 11.84RR263 pKa = 11.84LYY265 pKa = 10.69NRR267 pKa = 11.84LFEE270 pKa = 4.32QVPTRR275 pKa = 11.84NPYY278 pKa = 10.07FLGPVSRR285 pKa = 11.84AVQFEE290 pKa = 4.1YY291 pKa = 11.12SNPVFDD297 pKa = 5.66ADD299 pKa = 3.63VTVTFEE305 pKa = 3.99NDD307 pKa = 3.11LAEE310 pKa = 4.31IAAAPDD316 pKa = 3.23SDD318 pKa = 3.85FRR320 pKa = 11.84DD321 pKa = 3.63VQILHH326 pKa = 6.83RR327 pKa = 11.84PTYY330 pKa = 6.9TTTDD334 pKa = 2.84QGFIRR339 pKa = 11.84VSRR342 pKa = 11.84EE343 pKa = 3.2GARR346 pKa = 11.84ASITTRR352 pKa = 11.84SGLQLGRR359 pKa = 11.84PVHH362 pKa = 6.8FYY364 pKa = 11.03QDD366 pKa = 3.24LSAIEE371 pKa = 4.19SAEE374 pKa = 3.96SFEE377 pKa = 4.05MHH379 pKa = 6.57SLNTTSHH386 pKa = 6.5SSTTVNTLLDD396 pKa = 4.57SITVNPAYY404 pKa = 9.63EE405 pKa = 4.23DD406 pKa = 3.33PFYY409 pKa = 10.66PDD411 pKa = 5.85DD412 pKa = 4.32EE413 pKa = 5.36LLDD416 pKa = 4.4PLDD419 pKa = 3.49EE420 pKa = 4.46TFQRR424 pKa = 11.84GHH426 pKa = 6.19IVLTEE431 pKa = 4.06TNVDD435 pKa = 2.79GDD437 pKa = 4.37IIQFPTTLAEE447 pKa = 4.25SPVKK451 pKa = 10.86VFINDD456 pKa = 3.4YY457 pKa = 9.87GSSITVSYY465 pKa = 8.06PHH467 pKa = 7.02PAEE470 pKa = 4.16TASKK474 pKa = 9.88IIPIPSTDD482 pKa = 3.41NTPLLVLDD490 pKa = 4.93LTSDD494 pKa = 3.99DD495 pKa = 4.46YY496 pKa = 11.62FLHH499 pKa = 6.51PSLRR503 pKa = 11.84KK504 pKa = 9.4RR505 pKa = 11.84KK506 pKa = 9.36RR507 pKa = 11.84KK508 pKa = 9.97RR509 pKa = 11.84SDD511 pKa = 3.0VFF513 pKa = 3.52

Molecular weight: 55.89 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|K4MLG5|K4MLG5_9PAPI Major capsid protein L1 OS=Human papillomavirus type 161 OX=1315264 GN=L1 PE=3 SV=1
MM1 pKa = 7.44ACARR5 pKa = 11.84PLRR8 pKa = 11.84LDD10 pKa = 4.02DD11 pKa = 4.05FCAVYY16 pKa = 10.4SVSLFDD22 pKa = 4.7VSLPCIFCKK31 pKa = 10.4FVCDD35 pKa = 4.23LQDD38 pKa = 3.17LAAFHH43 pKa = 6.67IRR45 pKa = 11.84NLCLVWRR52 pKa = 11.84SEE54 pKa = 4.3QAFACCRR61 pKa = 11.84KK62 pKa = 10.0CINLSAKK69 pKa = 10.37YY70 pKa = 9.92EE71 pKa = 3.9YY72 pKa = 10.84DD73 pKa = 3.55NYY75 pKa = 10.71CVCIVNALSIEE86 pKa = 4.02QLLGLSLKK94 pKa = 10.81NIVIRR99 pKa = 11.84CLCCYY104 pKa = 10.12KK105 pKa = 10.81LLDD108 pKa = 3.61IAEE111 pKa = 4.86KK112 pKa = 10.74LDD114 pKa = 3.83CCAGNEE120 pKa = 3.95FFALVRR126 pKa = 11.84GTWRR130 pKa = 11.84GPCRR134 pKa = 11.84NCIRR138 pKa = 11.84KK139 pKa = 9.13RR140 pKa = 3.44

Molecular weight: 16.02 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

2253

97

604

375.5

42.36

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.814 ± 0.588

2.574 ± 1.13

6.968 ± 0.463

5.992 ± 0.56

4.749 ± 0.323

5.548 ± 0.772

1.687 ± 0.116

5.237 ± 0.778

5.237 ± 0.962

8.389 ± 0.942

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.687 ± 0.468

4.927 ± 0.449

6.214 ± 1.079

3.551 ± 0.309

5.814 ± 0.852

7.59 ± 0.635

6.436 ± 1.094

6.658 ± 0.311

1.509 ± 0.346

3.418 ± 0.156
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski