Amino acid dipepetide frequency for Cylindrobasidium torrendii FP15055 ss-10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.944AlaAla: 8.944 ± 0.058	1.172AlaCys: 1.172 ± 0.016	4.387AlaAsp: 4.387 ± 0.025	5.01AlaGlu: 5.01 ± 0.039	3.437AlaPhe: 3.437 ± 0.024	5.479AlaGly: 5.479 ± 0.035	2.13AlaHis: 2.13 ± 0.02	4.153AlaIle: 4.153 ± 0.034	4.053AlaLys: 4.053 ± 0.033	8.738AlaLeu: 8.738 ± 0.053	2.122AlaMet: 2.122 ± 0.017	2.861AlaAsn: 2.861 ± 0.026	5.598AlaPro: 5.598 ± 0.044	3.363AlaGln: 3.363 ± 0.024	5.451AlaArg: 5.451 ± 0.032	7.765AlaSer: 7.765 ± 0.045	5.282AlaThr: 5.282 ± 0.034	5.5AlaVal: 5.5 ± 0.032	1.228AlaTrp: 1.228 ± 0.016	2.426AlaTyr: 2.426 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	1.108CysAla: 1.108 ± 0.014	0.244CysCys: 0.244 ± 0.007	0.713CysAsp: 0.713 ± 0.013	0.621CysGlu: 0.621 ± 0.011	0.505CysPhe: 0.505 ± 0.01	0.925CysGly: 0.925 ± 0.014	0.335CysHis: 0.335 ± 0.008	0.761CysIle: 0.761 ± 0.014	0.53CysLys: 0.53 ± 0.01	1.27CysLeu: 1.27 ± 0.016	0.316CysMet: 0.316 ± 0.006	0.439CysAsn: 0.439 ± 0.011	0.831CysPro: 0.831 ± 0.014	0.445CysGln: 0.445 ± 0.011	0.838CysArg: 0.838 ± 0.015	1.013CysSer: 1.013 ± 0.015	0.826CysThr: 0.826 ± 0.013	0.882CysVal: 0.882 ± 0.014	0.211CysTrp: 0.211 ± 0.006	0.328CysTyr: 0.328 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	5.541AspAla: 5.541 ± 0.035	0.666AspCys: 0.666 ± 0.012	4.473AspAsp: 4.473 ± 0.045	4.621AspGlu: 4.621 ± 0.036	2.196AspPhe: 2.196 ± 0.018	4.122AspGly: 4.122 ± 0.028	1.163AspHis: 1.163 ± 0.015	3.272AspIle: 3.272 ± 0.025	2.227AspLys: 2.227 ± 0.026	4.966AspLeu: 4.966 ± 0.031	1.391AspMet: 1.391 ± 0.017	1.868AspAsn: 1.868 ± 0.02	3.17AspPro: 3.17 ± 0.024	1.546AspGln: 1.546 ± 0.019	2.698AspArg: 2.698 ± 0.025	4.172AspSer: 4.172 ± 0.029	3.169AspThr: 3.169 ± 0.023	4.142AspVal: 4.142 ± 0.032	0.965AspTrp: 0.965 ± 0.013	1.597AspTyr: 1.597 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.156GluAla: 5.156 ± 0.037	0.683GluCys: 0.683 ± 0.011	4.479GluAsp: 4.479 ± 0.038	5.172GluGlu: 5.172 ± 0.049	1.874GluPhe: 1.874 ± 0.02	3.579GluGly: 3.579 ± 0.029	1.512GluHis: 1.512 ± 0.019	2.725GluIle: 2.725 ± 0.022	3.076GluLys: 3.076 ± 0.029	5.24GluLeu: 5.24 ± 0.033	1.421GluMet: 1.421 ± 0.019	1.938GluAsn: 1.938 ± 0.018	2.769GluPro: 2.769 ± 0.028	2.203GluGln: 2.203 ± 0.021	4.043GluArg: 4.043 ± 0.034	3.909GluSer: 3.909 ± 0.025	3.079GluThr: 3.079 ± 0.025	3.559GluVal: 3.559 ± 0.029	0.956GluTrp: 0.956 ± 0.011	1.696GluTyr: 1.696 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.23PheAla: 3.23 ± 0.028	0.58PheCys: 0.58 ± 0.011	2.405PheAsp: 2.405 ± 0.024	2.106PheGlu: 2.106 ± 0.023	1.592PhePhe: 1.592 ± 0.021	2.77PheGly: 2.77 ± 0.028	0.895PheHis: 0.895 ± 0.013	1.797PheIle: 1.797 ± 0.021	1.549PheLys: 1.549 ± 0.019	3.457PheLeu: 3.457 ± 0.026	0.816PheMet: 0.816 ± 0.013	1.386PheAsn: 1.386 ± 0.018	2.128PhePro: 2.128 ± 0.02	1.217PheGln: 1.217 ± 0.014	1.959PheArg: 1.959 ± 0.02	2.971PheSer: 2.971 ± 0.022	2.209PheThr: 2.209 ± 0.019	2.602PheVal: 2.602 ± 0.023	0.627PheTrp: 0.627 ± 0.012	1.072PheTyr: 1.072 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	5.153GlyAla: 5.153 ± 0.039	0.9GlyCys: 0.9 ± 0.015	3.415GlyAsp: 3.415 ± 0.027	3.318GlyGlu: 3.318 ± 0.028	2.488GlyPhe: 2.488 ± 0.025	5.333GlyGly: 5.333 ± 0.056	1.676GlyHis: 1.676 ± 0.016	3.213GlyIle: 3.213 ± 0.027	3.248GlyLys: 3.248 ± 0.026	5.685GlyLeu: 5.685 ± 0.033	1.62GlyMet: 1.62 ± 0.021	2.17GlyAsn: 2.17 ± 0.022	3.194GlyPro: 3.194 ± 0.03	2.247GlyGln: 2.247 ± 0.02	3.989GlyArg: 3.989 ± 0.032	5.355GlySer: 5.355 ± 0.041	3.778GlyThr: 3.778 ± 0.03	4.253GlyVal: 4.253 ± 0.028	1.162GlyTrp: 1.162 ± 0.016	1.938GlyTyr: 1.938 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	2.094HisAla: 2.094 ± 0.022	0.394HisCys: 0.394 ± 0.009	1.333HisAsp: 1.333 ± 0.016	1.277HisGlu: 1.277 ± 0.015	1.014HisPhe: 1.014 ± 0.012	1.66HisGly: 1.66 ± 0.018	0.816HisHis: 0.816 ± 0.017	1.37HisIle: 1.37 ± 0.018	0.913HisLys: 0.913 ± 0.013	2.456HisLeu: 2.456 ± 0.024	0.467HisMet: 0.467 ± 0.009	0.871HisAsn: 0.871 ± 0.012	1.827HisPro: 1.827 ± 0.022	0.88HisGln: 0.88 ± 0.013	1.669HisArg: 1.669 ± 0.022	1.998HisSer: 1.998 ± 0.02	1.519HisThr: 1.519 ± 0.017	1.562HisVal: 1.562 ± 0.015	0.391HisTrp: 0.391 ± 0.009	0.722HisTyr: 0.722 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.115IleAla: 4.115 ± 0.033	0.698IleCys: 0.698 ± 0.013	2.779IleAsp: 2.779 ± 0.023	2.683IleGlu: 2.683 ± 0.025	1.924IlePhe: 1.924 ± 0.019	2.846IleGly: 2.846 ± 0.028	1.287IleHis: 1.287 ± 0.015	2.371IleIle: 2.371 ± 0.024	1.933IleLys: 1.933 ± 0.021	4.545IleLeu: 4.545 ± 0.029	0.987IleMet: 0.987 ± 0.014	1.52IleAsn: 1.52 ± 0.019	3.343IlePro: 3.343 ± 0.021	1.798IleGln: 1.798 ± 0.018	2.786IleArg: 2.786 ± 0.025	3.686IleSer: 3.686 ± 0.027	2.709IleThr: 2.709 ± 0.025	3.282IleVal: 3.282 ± 0.029	0.731IleTrp: 0.731 ± 0.011	1.271IleTyr: 1.271 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.23LysAla: 4.23 ± 0.034	0.516LysCys: 0.516 ± 0.01	2.722LysAsp: 2.722 ± 0.023	3.096LysGlu: 3.096 ± 0.027	1.369LysPhe: 1.369 ± 0.016	2.752LysGly: 2.752 ± 0.027	1.157LysHis: 1.157 ± 0.015	1.986LysIle: 1.986 ± 0.023	3.042LysLys: 3.042 ± 0.038	3.836LysLeu: 3.836 ± 0.028	1.004LysMet: 1.004 ± 0.013	1.546LysAsn: 1.546 ± 0.018	2.565LysPro: 2.565 ± 0.027	1.651LysGln: 1.651 ± 0.016	3.541LysArg: 3.541 ± 0.031	3.155LysSer: 3.155 ± 0.025	2.81LysThr: 2.81 ± 0.022	2.638LysVal: 2.638 ± 0.022	0.673LysTrp: 0.673 ± 0.012	1.289LysTyr: 1.289 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	8.148LeuAla: 8.148 ± 0.042	1.343LeuCys: 1.343 ± 0.017	5.465LeuAsp: 5.465 ± 0.034	5.603LeuGlu: 5.603 ± 0.041	3.447LeuPhe: 3.447 ± 0.028	5.647LeuGly: 5.647 ± 0.032	2.458LeuHis: 2.458 ± 0.022	3.663LeuIle: 3.663 ± 0.029	4.173LeuLys: 4.173 ± 0.033	8.362LeuLeu: 8.362 ± 0.062	1.761LeuMet: 1.761 ± 0.017	3.093LeuAsn: 3.093 ± 0.026	6.141LeuPro: 6.141 ± 0.038	3.554LeuGln: 3.554 ± 0.027	6.055LeuArg: 6.055 ± 0.038	7.627LeuSer: 7.627 ± 0.042	5.018LeuThr: 5.018 ± 0.035	5.902LeuVal: 5.902 ± 0.034	1.287LeuTrp: 1.287 ± 0.016	2.408LeuTyr: 2.408 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.103MetAla: 2.103 ± 0.019	0.269MetCys: 0.269 ± 0.006	1.429MetAsp: 1.429 ± 0.015	1.222MetGlu: 1.222 ± 0.015	0.817MetPhe: 0.817 ± 0.013	1.378MetGly: 1.378 ± 0.018	0.598MetHis: 0.598 ± 0.01	0.863MetIle: 0.863 ± 0.014	0.969MetLys: 0.969 ± 0.012	2.016MetLeu: 2.016 ± 0.019	0.552MetMet: 0.552 ± 0.011	0.794MetAsn: 0.794 ± 0.012	1.438MetPro: 1.438 ± 0.018	0.903MetGln: 0.903 ± 0.011	1.38MetArg: 1.38 ± 0.016	2.186MetSer: 2.186 ± 0.018	1.235MetThr: 1.235 ± 0.014	1.286MetVal: 1.286 ± 0.016	0.288MetTrp: 0.288 ± 0.007	0.618MetTyr: 0.618 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.259AsnAla: 3.259 ± 0.026	0.4AsnCys: 0.4 ± 0.009	1.867AsnAsp: 1.867 ± 0.019	1.819AsnGlu: 1.819 ± 0.017	1.262AsnPhe: 1.262 ± 0.014	2.595AsnGly: 2.595 ± 0.024	0.772AsnHis: 0.772 ± 0.013	1.934AsnIle: 1.934 ± 0.021	1.42AsnLys: 1.42 ± 0.019	3.039AsnLeu: 3.039 ± 0.025	0.792AsnMet: 0.792 ± 0.012	1.259AsnAsn: 1.259 ± 0.019	2.217AsnPro: 2.217 ± 0.022	1.083AsnGln: 1.083 ± 0.013	1.688AsnArg: 1.688 ± 0.018	2.403AsnSer: 2.403 ± 0.022	2.123AsnThr: 2.123 ± 0.02	2.417AsnVal: 2.417 ± 0.02	0.531AsnTrp: 0.531 ± 0.008	0.901AsnTyr: 0.901 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.799ProAla: 5.799 ± 0.048	0.598ProCys: 0.598 ± 0.013	3.242ProAsp: 3.242 ± 0.024	3.668ProGlu: 3.668 ± 0.026	2.197ProPhe: 2.197 ± 0.019	3.603ProGly: 3.603 ± 0.031	1.468ProHis: 1.468 ± 0.019	2.642ProIle: 2.642 ± 0.023	2.651ProLys: 2.651 ± 0.027	5.165ProLeu: 5.165 ± 0.032	1.241ProMet: 1.241 ± 0.019	2.111ProAsn: 2.111 ± 0.02	6.321ProPro: 6.321 ± 0.069	2.317ProGln: 2.317 ± 0.025	3.712ProArg: 3.712 ± 0.031	6.845ProSer: 6.845 ± 0.054	4.554ProThr: 4.554 ± 0.035	3.844ProVal: 3.844 ± 0.029	0.798ProTrp: 0.798 ± 0.013	1.581ProTyr: 1.581 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.378GlnAla: 3.378 ± 0.026	0.522GlnCys: 0.522 ± 0.01	2.031GlnAsp: 2.031 ± 0.02	2.145GlnGlu: 2.145 ± 0.023	1.192GlnPhe: 1.192 ± 0.016	1.99GlnGly: 1.99 ± 0.02	1.046GlnHis: 1.046 ± 0.015	1.581GlnIle: 1.581 ± 0.016	1.599GlnLys: 1.599 ± 0.018	3.234GlnLeu: 3.234 ± 0.025	0.85GlnMet: 0.85 ± 0.013	1.246GlnAsn: 1.246 ± 0.015	2.342GlnPro: 2.342 ± 0.027	1.864GlnGln: 1.864 ± 0.036	2.664GlnArg: 2.664 ± 0.022	2.806GlnSer: 2.806 ± 0.026	2.18GlnThr: 2.18 ± 0.022	2.09GlnVal: 2.09 ± 0.02	0.6GlnTrp: 0.6 ± 0.011	1.079GlnTyr: 1.079 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	5.43ArgAla: 5.43 ± 0.034	0.828ArgCys: 0.828 ± 0.012	3.216ArgAsp: 3.216 ± 0.028	3.685ArgGlu: 3.685 ± 0.035	2.148ArgPhe: 2.148 ± 0.021	3.542ArgGly: 3.542 ± 0.031	1.619ArgHis: 1.619 ± 0.02	3.02ArgIle: 3.02 ± 0.02	3.389ArgLys: 3.389 ± 0.031	5.783ArgLeu: 5.783 ± 0.033	1.493ArgMet: 1.493 ± 0.017	2.032ArgAsn: 2.032 ± 0.018	3.768ArgPro: 3.768 ± 0.036	2.5ArgGln: 2.5 ± 0.023	5.398ArgArg: 5.398 ± 0.047	4.732ArgSer: 4.732 ± 0.038	3.768ArgThr: 3.768 ± 0.028	3.751ArgVal: 3.751 ± 0.025	1.003ArgTrp: 1.003 ± 0.014	1.649ArgTyr: 1.649 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	7.136SerAla: 7.136 ± 0.044	0.939SerCys: 0.939 ± 0.016	4.304SerAsp: 4.304 ± 0.028	3.851SerGlu: 3.851 ± 0.026	3.137SerPhe: 3.137 ± 0.026	5.322SerGly: 5.322 ± 0.033	1.983SerHis: 1.983 ± 0.021	3.876SerIle: 3.876 ± 0.028	3.527SerLys: 3.527 ± 0.026	7.497SerLeu: 7.497 ± 0.043	1.807SerMet: 1.807 ± 0.017	2.753SerAsn: 2.753 ± 0.023	5.919SerPro: 5.919 ± 0.057	2.892SerGln: 2.892 ± 0.023	4.996SerArg: 4.996 ± 0.037	9.073SerSer: 9.073 ± 0.074	5.894SerThr: 5.894 ± 0.041	5.049SerVal: 5.049 ± 0.038	1.098SerTrp: 1.098 ± 0.016	2.021SerTyr: 2.021 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.176ThrAla: 5.176 ± 0.032	0.778ThrCys: 0.778 ± 0.013	2.912ThrAsp: 2.912 ± 0.024	2.904ThrGlu: 2.904 ± 0.021	2.469ThrPhe: 2.469 ± 0.021	3.81ThrGly: 3.81 ± 0.031	1.504ThrHis: 1.504 ± 0.018	3.024ThrIle: 3.024 ± 0.025	2.494ThrLys: 2.494 ± 0.02	5.916ThrLeu: 5.916 ± 0.035	1.301ThrMet: 1.301 ± 0.015	1.983ThrAsn: 1.983 ± 0.018	4.702ThrPro: 4.702 ± 0.041	2.079ThrGln: 2.079 ± 0.019	3.476ThrArg: 3.476 ± 0.024	5.543ThrSer: 5.543 ± 0.045	4.232ThrThr: 4.232 ± 0.037	3.974ThrVal: 3.974 ± 0.028	0.843ThrTrp: 0.843 ± 0.014	1.606ThrTyr: 1.606 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.534ValAla: 5.534 ± 0.031	0.977ValCys: 0.977 ± 0.013	4.109ValAsp: 4.109 ± 0.03	3.909ValGlu: 3.909 ± 0.027	2.6ValPhe: 2.6 ± 0.024	3.949ValGly: 3.949 ± 0.031	1.696ValHis: 1.696 ± 0.016	2.878ValIle: 2.878 ± 0.024	2.916ValLys: 2.916 ± 0.024	6.124ValLeu: 6.124 ± 0.031	1.342ValMet: 1.342 ± 0.015	2.166ValAsn: 2.166 ± 0.022	3.858ValPro: 3.858 ± 0.032	2.422ValGln: 2.422 ± 0.02	3.73ValArg: 3.73 ± 0.029	4.73ValSer: 4.73 ± 0.032	3.544ValThr: 3.544 ± 0.027	4.628ValVal: 4.628 ± 0.038	0.974ValTrp: 0.974 ± 0.014	1.896ValTyr: 1.896 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.181TrpAla: 1.181 ± 0.014	0.222TrpCys: 0.222 ± 0.006	0.975TrpAsp: 0.975 ± 0.016	0.882TrpGlu: 0.882 ± 0.012	0.557TrpPhe: 0.557 ± 0.01	0.901TrpGly: 0.901 ± 0.015	0.384TrpHis: 0.384 ± 0.009	0.766TrpIle: 0.766 ± 0.012	0.805TrpLys: 0.805 ± 0.012	1.293TrpLeu: 1.293 ± 0.015	0.428TrpMet: 0.428 ± 0.008	0.648TrpAsn: 0.648 ± 0.013	0.679TrpPro: 0.679 ± 0.011	0.517TrpGln: 0.517 ± 0.01	1.085TrpArg: 1.085 ± 0.013	1.103TrpSer: 1.103 ± 0.014	1.02TrpThr: 1.02 ± 0.014	0.906TrpVal: 0.906 ± 0.012	0.303TrpTrp: 0.303 ± 0.007	0.429TrpTyr: 0.429 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.386TyrAla: 2.386 ± 0.021	0.414TyrCys: 0.414 ± 0.009	1.71TyrAsp: 1.71 ± 0.017	1.476TyrGlu: 1.476 ± 0.016	1.142TyrPhe: 1.142 ± 0.016	1.934TyrGly: 1.934 ± 0.021	0.732TyrHis: 0.732 ± 0.011	1.398TyrIle: 1.398 ± 0.017	1.066TyrLys: 1.066 ± 0.015	2.535TyrLeu: 2.535 ± 0.023	0.63TyrMet: 0.63 ± 0.011	1.093TyrAsn: 1.093 ± 0.014	1.546TyrPro: 1.546 ± 0.017	0.96TyrGln: 0.96 ± 0.014	1.595TyrArg: 1.595 ± 0.017	2.0TyrSer: 2.0 ± 0.021	1.778TyrThr: 1.778 ± 0.018	1.716TyrVal: 1.716 ± 0.018	0.417TyrTrp: 0.417 ± 0.008	0.882TyrTyr: 0.882 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13901 proteins (5747761 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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