Amino acid dipepetide frequency for Carpinus fangiana

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.679AlaAla: 7.679 ± 0.042	1.336AlaCys: 1.336 ± 0.012	3.617AlaAsp: 3.617 ± 0.02	4.574AlaGlu: 4.574 ± 0.024	2.953AlaPhe: 2.953 ± 0.018	5.021AlaGly: 5.021 ± 0.025	1.621AlaHis: 1.621 ± 0.013	3.927AlaIle: 3.927 ± 0.021	3.965AlaLys: 3.965 ± 0.019	7.376AlaLeu: 7.376 ± 0.028	1.895AlaMet: 1.895 ± 0.013	2.707AlaAsn: 2.707 ± 0.015	3.618AlaPro: 3.618 ± 0.023	2.651AlaGln: 2.651 ± 0.017	4.195AlaArg: 4.195 ± 0.023	6.776AlaSer: 6.776 ± 0.028	4.177AlaThr: 4.177 ± 0.022	5.224AlaVal: 5.224 ± 0.028	0.946AlaTrp: 0.946 ± 0.009	1.935AlaTyr: 1.935 ± 0.013	0.0AlaXaa: 0.0 ± 0.0
Cys	1.09CysAla: 1.09 ± 0.011	0.483CysCys: 0.483 ± 0.007	0.801CysAsp: 0.801 ± 0.009	0.857CysGlu: 0.857 ± 0.009	0.824CysPhe: 0.824 ± 0.008	1.344CysGly: 1.344 ± 0.013	0.459CysHis: 0.459 ± 0.006	0.917CysIle: 0.917 ± 0.009	0.996CysLys: 0.996 ± 0.01	1.776CysLeu: 1.776 ± 0.013	0.429CysMet: 0.429 ± 0.006	0.74CysAsn: 0.74 ± 0.008	0.913CysPro: 0.913 ± 0.01	0.582CysGln: 0.582 ± 0.007	1.052CysArg: 1.052 ± 0.01	1.636CysSer: 1.636 ± 0.012	0.855CysThr: 0.855 ± 0.009	1.016CysVal: 1.016 ± 0.009	0.241CysTrp: 0.241 ± 0.004	0.479CysTyr: 0.479 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.027AspAla: 4.027 ± 0.02	0.889AspCys: 0.889 ± 0.009	3.703AspAsp: 3.703 ± 0.025	4.032AspGlu: 4.032 ± 0.023	2.238AspPhe: 2.238 ± 0.015	4.042AspGly: 4.042 ± 0.022	1.281AspHis: 1.281 ± 0.011	2.865AspIle: 2.865 ± 0.018	2.49AspLys: 2.49 ± 0.015	5.016AspLeu: 5.016 ± 0.022	1.32AspMet: 1.32 ± 0.012	1.939AspAsn: 1.939 ± 0.014	2.805AspPro: 2.805 ± 0.017	1.813AspGln: 1.813 ± 0.011	2.608AspArg: 2.608 ± 0.018	4.15AspSer: 4.15 ± 0.022	2.38AspThr: 2.38 ± 0.014	3.619AspVal: 3.619 ± 0.019	0.736AspTrp: 0.736 ± 0.008	1.472AspTyr: 1.472 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	5.124GluAla: 5.124 ± 0.023	0.841GluCys: 0.841 ± 0.01	3.96GluAsp: 3.96 ± 0.023	5.872GluGlu: 5.872 ± 0.039	2.154GluPhe: 2.154 ± 0.014	3.872GluGly: 3.872 ± 0.02	1.338GluHis: 1.338 ± 0.011	3.412GluIle: 3.412 ± 0.017	4.329GluLys: 4.329 ± 0.027	5.715GluLeu: 5.715 ± 0.028	1.66GluMet: 1.66 ± 0.013	2.728GluAsn: 2.728 ± 0.019	2.327GluPro: 2.327 ± 0.016	2.283GluGln: 2.283 ± 0.014	3.722GluArg: 3.722 ± 0.022	4.409GluSer: 4.409 ± 0.025	3.037GluThr: 3.037 ± 0.018	4.073GluVal: 4.073 ± 0.022	0.748GluTrp: 0.748 ± 0.008	1.545GluTyr: 1.545 ± 0.01	0.001GluXaa: 0.001 ± 0.0
Phe	2.732PheAla: 2.732 ± 0.017	0.832PheCys: 0.832 ± 0.009	2.301PheAsp: 2.301 ± 0.013	2.236PheGlu: 2.236 ± 0.015	1.848PhePhe: 1.848 ± 0.014	2.98PheGly: 2.98 ± 0.017	1.053PheHis: 1.053 ± 0.009	1.867PheIle: 1.867 ± 0.013	1.892PheLys: 1.892 ± 0.012	4.056PheLeu: 4.056 ± 0.025	0.897PheMet: 0.897 ± 0.009	1.588PheAsn: 1.588 ± 0.013	2.042PhePro: 2.042 ± 0.015	1.489PheGln: 1.489 ± 0.012	2.03PheArg: 2.03 ± 0.011	3.759PheSer: 3.759 ± 0.022	1.978PheThr: 1.978 ± 0.014	2.654PheVal: 2.654 ± 0.018	0.562PheTrp: 0.562 ± 0.007	1.159PheTyr: 1.159 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	4.654GlyAla: 4.654 ± 0.023	1.283GlyCys: 1.283 ± 0.013	3.572GlyAsp: 3.572 ± 0.018	3.841GlyGlu: 3.841 ± 0.024	3.115GlyPhe: 3.115 ± 0.019	5.866GlyGly: 5.866 ± 0.042	1.699GlyHis: 1.699 ± 0.012	3.526GlyIle: 3.526 ± 0.018	3.932GlyLys: 3.932 ± 0.02	6.161GlyLeu: 6.161 ± 0.023	1.568GlyMet: 1.568 ± 0.011	2.928GlyAsn: 2.928 ± 0.016	2.801GlyPro: 2.801 ± 0.018	2.274GlyGln: 2.274 ± 0.014	4.053GlyArg: 4.053 ± 0.027	6.094GlySer: 6.094 ± 0.028	3.378GlyThr: 3.378 ± 0.019	4.498GlyVal: 4.498 ± 0.022	1.019GlyTrp: 1.019 ± 0.009	2.008GlyTyr: 2.008 ± 0.016	0.001GlyXaa: 0.001 ± 0.0
His	1.731HisAla: 1.731 ± 0.014	0.493HisCys: 0.493 ± 0.007	1.232HisAsp: 1.232 ± 0.008	1.327HisGlu: 1.327 ± 0.011	1.022HisPhe: 1.022 ± 0.009	1.868HisGly: 1.868 ± 0.014	0.954HisHis: 0.954 ± 0.012	1.206HisIle: 1.206 ± 0.011	1.116HisLys: 1.116 ± 0.01	2.419HisLeu: 2.419 ± 0.015	0.557HisMet: 0.557 ± 0.007	0.915HisAsn: 0.915 ± 0.009	1.518HisPro: 1.518 ± 0.013	1.009HisGln: 1.009 ± 0.01	1.484HisArg: 1.484 ± 0.012	2.028HisSer: 2.028 ± 0.015	1.086HisThr: 1.086 ± 0.01	1.603HisVal: 1.603 ± 0.013	0.323HisTrp: 0.323 ± 0.005	0.687HisTyr: 0.687 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.701IleAla: 3.701 ± 0.019	0.995IleCys: 0.995 ± 0.009	2.794IleAsp: 2.794 ± 0.015	3.006IleGlu: 3.006 ± 0.019	2.148IlePhe: 2.148 ± 0.014	3.263IleGly: 3.263 ± 0.016	1.216IleHis: 1.216 ± 0.01	2.566IleIle: 2.566 ± 0.017	2.598IleLys: 2.598 ± 0.015	4.889IleLeu: 4.889 ± 0.022	1.078IleMet: 1.078 ± 0.01	1.948IleAsn: 1.948 ± 0.016	2.884IlePro: 2.884 ± 0.021	1.852IleGln: 1.852 ± 0.013	2.616IleArg: 2.616 ± 0.015	4.481IleSer: 4.481 ± 0.02	2.549IleThr: 2.549 ± 0.015	3.272IleVal: 3.272 ± 0.02	0.688IleTrp: 0.688 ± 0.009	1.431IleTyr: 1.431 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	4.161LysAla: 4.161 ± 0.019	0.849LysCys: 0.849 ± 0.009	3.055LysAsp: 3.055 ± 0.015	4.148LysGlu: 4.148 ± 0.026	1.87LysPhe: 1.87 ± 0.011	3.431LysGly: 3.431 ± 0.02	1.292LysHis: 1.292 ± 0.01	2.833LysIle: 2.833 ± 0.016	4.137LysLys: 4.137 ± 0.025	5.328LysLeu: 5.328 ± 0.024	1.367LysMet: 1.367 ± 0.011	2.321LysAsn: 2.321 ± 0.015	2.776LysPro: 2.776 ± 0.018	2.129LysGln: 2.129 ± 0.014	3.559LysArg: 3.559 ± 0.022	4.218LysSer: 4.218 ± 0.024	2.718LysThr: 2.718 ± 0.016	3.493LysVal: 3.493 ± 0.019	0.749LysTrp: 0.749 ± 0.008	1.481LysTyr: 1.481 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	7.25LeuAla: 7.25 ± 0.033	1.74LeuCys: 1.74 ± 0.013	5.111LeuAsp: 5.111 ± 0.022	6.084LeuGlu: 6.084 ± 0.029	3.666LeuPhe: 3.666 ± 0.023	6.012LeuGly: 6.012 ± 0.025	2.591LeuHis: 2.591 ± 0.019	4.288LeuIle: 4.288 ± 0.023	5.493LeuLys: 5.493 ± 0.023	9.75LeuLeu: 9.75 ± 0.045	2.025LeuMet: 2.025 ± 0.015	3.601LeuAsn: 3.601 ± 0.018	5.386LeuPro: 5.386 ± 0.024	4.203LeuGln: 4.203 ± 0.023	5.673LeuArg: 5.673 ± 0.026	8.336LeuSer: 8.336 ± 0.039	4.485LeuThr: 4.485 ± 0.022	6.223LeuVal: 6.223 ± 0.026	1.167LeuTrp: 1.167 ± 0.01	2.411LeuTyr: 2.411 ± 0.015	0.0LeuXaa: 0.0 ± 0.0
Met	2.235MetAla: 2.235 ± 0.013	0.314MetCys: 0.314 ± 0.005	1.375MetAsp: 1.375 ± 0.01	1.81MetGlu: 1.81 ± 0.014	0.763MetPhe: 0.763 ± 0.007	1.646MetGly: 1.646 ± 0.011	0.533MetHis: 0.533 ± 0.006	1.087MetIle: 1.087 ± 0.01	1.449MetLys: 1.449 ± 0.011	2.118MetLeu: 2.118 ± 0.015	0.633MetMet: 0.633 ± 0.008	0.904MetAsn: 0.904 ± 0.009	1.152MetPro: 1.152 ± 0.011	0.898MetGln: 0.898 ± 0.009	1.25MetArg: 1.25 ± 0.01	1.757MetSer: 1.757 ± 0.012	1.076MetThr: 1.076 ± 0.008	1.564MetVal: 1.564 ± 0.013	0.264MetTrp: 0.264 ± 0.004	0.563MetTyr: 0.563 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.83AsnAla: 2.83 ± 0.016	0.728AsnCys: 0.728 ± 0.008	1.962AsnAsp: 1.962 ± 0.014	2.275AsnGlu: 2.275 ± 0.015	1.73AsnPhe: 1.73 ± 0.013	3.161AsnGly: 3.161 ± 0.019	0.996AsnHis: 0.996 ± 0.009	2.195AsnIle: 2.195 ± 0.014	2.019AsnLys: 2.019 ± 0.015	4.079AsnLeu: 4.079 ± 0.022	0.995AsnMet: 0.995 ± 0.01	1.86AsnAsn: 1.86 ± 0.02	2.355AsnPro: 2.355 ± 0.015	1.519AsnGln: 1.519 ± 0.012	1.953AsnArg: 1.953 ± 0.013	3.508AsnSer: 3.508 ± 0.02	1.945AsnThr: 1.945 ± 0.015	2.6AsnVal: 2.6 ± 0.015	0.538AsnTrp: 0.538 ± 0.007	1.179AsnTyr: 1.179 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	3.925ProAla: 3.925 ± 0.025	0.793ProCys: 0.793 ± 0.009	2.671ProAsp: 2.671 ± 0.016	3.208ProGlu: 3.208 ± 0.018	2.045ProPhe: 2.045 ± 0.015	3.115ProGly: 3.115 ± 0.019	1.29ProHis: 1.29 ± 0.012	2.402ProIle: 2.402 ± 0.014	2.706ProLys: 2.706 ± 0.017	4.638ProLeu: 4.638 ± 0.025	1.027ProMet: 1.027 ± 0.009	2.261ProAsn: 2.261 ± 0.016	4.535ProPro: 4.535 ± 0.063	2.006ProGln: 2.006 ± 0.015	2.826ProArg: 2.826 ± 0.019	5.498ProSer: 5.498 ± 0.031	3.13ProThr: 3.13 ± 0.018	3.215ProVal: 3.215 ± 0.019	0.668ProTrp: 0.668 ± 0.006	1.352ProTyr: 1.352 ± 0.012	0.001ProXaa: 0.001 ± 0.0
Gln	2.812GlnAla: 2.812 ± 0.017	0.565GlnCys: 0.565 ± 0.007	1.779GlnAsp: 1.779 ± 0.013	2.382GlnGlu: 2.382 ± 0.015	1.299GlnPhe: 1.299 ± 0.009	2.224GlnGly: 2.224 ± 0.015	1.001GlnHis: 1.001 ± 0.01	1.922GlnIle: 1.922 ± 0.014	2.237GlnLys: 2.237 ± 0.016	3.593GlnLeu: 3.593 ± 0.018	0.941GlnMet: 0.941 ± 0.009	1.643GlnAsn: 1.643 ± 0.013	2.051GlnPro: 2.051 ± 0.016	2.117GlnGln: 2.117 ± 0.025	2.412GlnArg: 2.412 ± 0.017	2.965GlnSer: 2.965 ± 0.016	1.879GlnThr: 1.879 ± 0.013	2.295GlnVal: 2.295 ± 0.013	0.499GlnTrp: 0.499 ± 0.007	0.962GlnTyr: 0.962 ± 0.01	0.0GlnXaa: 0.0 ± 0.0
Arg	4.068ArgAla: 4.068 ± 0.025	0.987ArgCys: 0.987 ± 0.01	2.862ArgAsp: 2.862 ± 0.018	3.578ArgGlu: 3.578 ± 0.021	2.204ArgPhe: 2.204 ± 0.015	3.593ArgGly: 3.593 ± 0.025	1.472ArgHis: 1.472 ± 0.013	2.825ArgIle: 2.825 ± 0.016	3.714ArgLys: 3.714 ± 0.02	5.312ArgLeu: 5.312 ± 0.026	1.376ArgMet: 1.376 ± 0.01	2.376ArgAsn: 2.376 ± 0.013	2.875ArgPro: 2.875 ± 0.021	2.167ArgGln: 2.167 ± 0.015	4.633ArgArg: 4.633 ± 0.029	4.666ArgSer: 4.666 ± 0.028	2.756ArgThr: 2.756 ± 0.017	3.511ArgVal: 3.511 ± 0.018	0.838ArgTrp: 0.838 ± 0.009	1.411ArgTyr: 1.411 ± 0.011	0.0ArgXaa: 0.0 ± 0.0
Ser	6.113SerAla: 6.113 ± 0.026	1.575SerCys: 1.575 ± 0.013	4.33SerAsp: 4.33 ± 0.021	4.582SerGlu: 4.582 ± 0.023	3.68SerPhe: 3.68 ± 0.019	5.989SerGly: 5.989 ± 0.028	2.076SerHis: 2.076 ± 0.014	4.276SerIle: 4.276 ± 0.019	4.529SerLys: 4.529 ± 0.023	8.371SerLeu: 8.371 ± 0.032	2.018SerMet: 2.018 ± 0.012	3.696SerAsn: 3.696 ± 0.02	4.973SerPro: 4.973 ± 0.033	3.097SerGln: 3.097 ± 0.016	4.771SerArg: 4.771 ± 0.023	10.405SerSer: 10.405 ± 0.051	4.94SerThr: 4.94 ± 0.022	5.1SerVal: 5.1 ± 0.021	1.198SerTrp: 1.198 ± 0.012	2.198SerTyr: 2.198 ± 0.015	0.0SerXaa: 0.0 ± 0.0
Thr	4.02ThrAla: 4.02 ± 0.018	0.88ThrCys: 0.88 ± 0.01	2.349ThrAsp: 2.349 ± 0.014	2.72ThrGlu: 2.72 ± 0.015	2.055ThrPhe: 2.055 ± 0.014	3.486ThrGly: 3.486 ± 0.017	1.174ThrHis: 1.174 ± 0.01	2.7ThrIle: 2.7 ± 0.017	2.597ThrLys: 2.597 ± 0.016	4.782ThrLeu: 4.782 ± 0.02	1.151ThrMet: 1.151 ± 0.009	2.014ThrAsn: 2.014 ± 0.013	3.086ThrPro: 3.086 ± 0.021	1.728ThrGln: 1.728 ± 0.013	2.639ThrArg: 2.639 ± 0.015	4.776ThrSer: 4.776 ± 0.021	3.231ThrThr: 3.231 ± 0.019	3.354ThrVal: 3.354 ± 0.019	0.685ThrTrp: 0.685 ± 0.007	1.372ThrTyr: 1.372 ± 0.012	0.0ThrXaa: 0.0 ± 0.0
Val	5.219ValAla: 5.219 ± 0.026	1.116ValCys: 1.116 ± 0.01	3.751ValAsp: 3.751 ± 0.019	4.352ValGlu: 4.352 ± 0.021	2.608ValPhe: 2.608 ± 0.017	4.464ValGly: 4.464 ± 0.021	1.521ValHis: 1.521 ± 0.012	3.145ValIle: 3.145 ± 0.018	3.492ValLys: 3.492 ± 0.023	6.27ValLeu: 6.27 ± 0.028	1.437ValMet: 1.437 ± 0.01	2.416ValAsn: 2.416 ± 0.014	3.352ValPro: 3.352 ± 0.019	2.334ValGln: 2.334 ± 0.016	3.37ValArg: 3.37 ± 0.018	5.27ValSer: 5.27 ± 0.022	3.165ValThr: 3.165 ± 0.018	4.933ValVal: 4.933 ± 0.028	0.824ValTrp: 0.824 ± 0.009	1.799ValTyr: 1.799 ± 0.012	0.0ValXaa: 0.0 ± 0.0
Trp	0.913TrpAla: 0.913 ± 0.009	0.231TrpCys: 0.231 ± 0.005	0.706TrpAsp: 0.706 ± 0.008	0.774TrpGlu: 0.774 ± 0.009	0.525TrpPhe: 0.525 ± 0.006	0.813TrpGly: 0.813 ± 0.008	0.322TrpHis: 0.322 ± 0.005	0.686TrpIle: 0.686 ± 0.008	0.877TrpLys: 0.877 ± 0.009	1.292TrpLeu: 1.292 ± 0.009	0.351TrpMet: 0.351 ± 0.006	0.647TrpAsn: 0.647 ± 0.008	0.569TrpPro: 0.569 ± 0.007	0.502TrpGln: 0.502 ± 0.005	0.92TrpArg: 0.92 ± 0.008	1.027TrpSer: 1.027 ± 0.01	0.703TrpThr: 0.703 ± 0.008	0.892TrpVal: 0.892 ± 0.008	0.262TrpTrp: 0.262 ± 0.005	0.345TrpTyr: 0.345 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.91TyrAla: 1.91 ± 0.013	0.561TyrCys: 0.561 ± 0.007	1.496TyrAsp: 1.496 ± 0.011	1.49TyrGlu: 1.49 ± 0.012	1.209TyrPhe: 1.209 ± 0.01	2.079TyrGly: 2.079 ± 0.016	0.691TyrHis: 0.691 ± 0.008	1.33TyrIle: 1.33 ± 0.01	1.346TyrLys: 1.346 ± 0.012	2.554TyrLeu: 2.554 ± 0.016	0.664TyrMet: 0.664 ± 0.008	1.192TyrAsn: 1.192 ± 0.013	1.293TyrPro: 1.293 ± 0.012	0.926TyrGln: 0.926 ± 0.008	1.46TyrArg: 1.46 ± 0.011	2.158TyrSer: 2.158 ± 0.014	1.329TyrThr: 1.329 ± 0.011	1.7TyrVal: 1.7 ± 0.014	0.402TyrTrp: 0.402 ± 0.006	0.899TyrTyr: 0.899 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.004XaaXaa: 0.004 ± 0.002

Statistics based on 28539 proteins (12421239 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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