Human papillomavirus 95

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 1

Average proteome isoelectric point is 6.07

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q705D9|Q705D9_9PAPI Protein E6 OS=Human papillomavirus 95 OX=260716 GN=E6 PE=3 SV=1
MM1 pKa = 7.66RR2 pKa = 11.84GAAPSIADD10 pKa = 3.08VDD12 pKa = 4.75LNLHH16 pKa = 5.7EE17 pKa = 4.95LVVPANLLSDD27 pKa = 4.06EE28 pKa = 4.19VLQLSEE34 pKa = 4.59EE35 pKa = 4.11EE36 pKa = 4.09DD37 pKa = 3.57EE38 pKa = 4.34EE39 pKa = 5.32RR40 pKa = 11.84EE41 pKa = 4.1EE42 pKa = 3.9EE43 pKa = 4.21LLPFRR48 pKa = 11.84IDD50 pKa = 3.36TCCYY54 pKa = 8.45NCEE57 pKa = 3.98ANVRR61 pKa = 11.84ITLYY65 pKa = 10.87AVAFGLRR72 pKa = 11.84VVEE75 pKa = 4.13QLLLEE80 pKa = 4.43GKK82 pKa = 10.39VIFCCVGCARR92 pKa = 11.84NHH94 pKa = 5.62SRR96 pKa = 11.84NGRR99 pKa = 3.51

Molecular weight: 11.11 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q705D7|Q705D7_9PAPI Replication protein E1 OS=Human papillomavirus 95 OX=260716 GN=E1 PE=3 SV=1
MM1 pKa = 7.49EE2 pKa = 4.93SLVARR7 pKa = 11.84FDD9 pKa = 3.76ALQEE13 pKa = 4.31EE14 pKa = 5.26ILTHH18 pKa = 6.12IEE20 pKa = 4.05SGNTTLEE27 pKa = 3.98SQIKK31 pKa = 8.43YY32 pKa = 8.62WEE34 pKa = 4.07NVRR37 pKa = 11.84KK38 pKa = 9.83EE39 pKa = 4.08NAIMHH44 pKa = 6.27YY45 pKa = 10.3ARR47 pKa = 11.84KK48 pKa = 9.64QGLTKK53 pKa = 10.71LGLQPLPSLLASEE66 pKa = 5.1YY67 pKa = 9.95NAKK70 pKa = 9.87QAIQIQLTLLSLLKK84 pKa = 10.42SPYY87 pKa = 10.39ASEE90 pKa = 4.14PWTLPEE96 pKa = 4.76VSAEE100 pKa = 4.51LINTPPQNVLKK111 pKa = 10.8KK112 pKa = 10.1GGYY115 pKa = 9.85DD116 pKa = 3.23VTVWFDD122 pKa = 3.53DD123 pKa = 3.64DD124 pKa = 4.72RR125 pKa = 11.84NNTMVYY131 pKa = 9.33TNWTALYY138 pKa = 9.14YY139 pKa = 10.38QDD141 pKa = 5.8ANEE144 pKa = 3.99IWHH147 pKa = 5.82KK148 pKa = 11.04VKK150 pKa = 11.28GEE152 pKa = 3.56VDD154 pKa = 3.54YY155 pKa = 11.87NGLFFTDD162 pKa = 3.49HH163 pKa = 5.87TGEE166 pKa = 3.88RR167 pKa = 11.84AYY169 pKa = 9.63FTLFSTDD176 pKa = 3.02AEE178 pKa = 4.45RR179 pKa = 11.84YY180 pKa = 8.4SQTGLWTVHH189 pKa = 6.5FKK191 pKa = 9.38TQVISSSVVSSTNPSSFDD209 pKa = 3.89FEE211 pKa = 4.35EE212 pKa = 4.16QLPGPSTSNTKK223 pKa = 7.1TTKK226 pKa = 8.45QTSPRR231 pKa = 11.84GRR233 pKa = 11.84GSQSRR238 pKa = 11.84EE239 pKa = 3.92LQPSSTTSPEE249 pKa = 4.12GKK251 pKa = 9.4GLRR254 pKa = 11.84VRR256 pKa = 11.84RR257 pKa = 11.84RR258 pKa = 11.84RR259 pKa = 11.84GQGEE263 pKa = 4.33SGSGTRR269 pKa = 11.84EE270 pKa = 3.88TPSKK274 pKa = 10.16RR275 pKa = 11.84RR276 pKa = 11.84RR277 pKa = 11.84GGGGRR282 pKa = 11.84GEE284 pKa = 4.51KK285 pKa = 10.35EE286 pKa = 4.09FGSAPTPSEE295 pKa = 3.65VGSRR299 pKa = 11.84HH300 pKa = 5.18RR301 pKa = 11.84QVEE304 pKa = 4.54TKK306 pKa = 10.28GLSRR310 pKa = 11.84LGQLQADD317 pKa = 3.78ARR319 pKa = 11.84DD320 pKa = 3.75PPMIMLKK327 pKa = 10.41GHH329 pKa = 6.64ANSLKK334 pKa = 8.57CWRR337 pKa = 11.84YY338 pKa = 9.8RR339 pKa = 11.84KK340 pKa = 8.39LTSNSCGFLYY350 pKa = 10.27MSTVWNWVGDD360 pKa = 3.62SSEE363 pKa = 3.91NHH365 pKa = 5.49SRR367 pKa = 11.84MLIAFTSTDD376 pKa = 3.11QRR378 pKa = 11.84DD379 pKa = 4.26YY380 pKa = 10.92FVKK383 pKa = 9.99HH384 pKa = 5.95HH385 pKa = 6.63FFPRR389 pKa = 11.84QCTYY393 pKa = 10.89TFGSLNSLL401 pKa = 3.86

Molecular weight: 45.35 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2447

99

601

349.6

39.36

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.517 ± 0.414

2.207 ± 0.718

6.457 ± 0.646

6.293 ± 0.516

4.373 ± 0.574

6.416 ± 0.833

1.839 ± 0.27

5.272 ± 0.859

4.863 ± 0.906

9.44 ± 0.653

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.389 ± 0.324

4.373 ± 0.51

6.089 ± 1.047

4.863 ± 0.263

5.926 ± 0.534

7.928 ± 0.844

6.293 ± 0.857

5.517 ± 0.515

1.226 ± 0.36

3.719 ± 0.381
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski