Amino acid dipepetide frequency for Tacaribe virus (strain Franze-Fernandez) (TCRV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.078AlaAla: 2.078 ± 1.072
0.89AlaCys: 0.89 ± 0.321
1.781AlaAsp: 1.781 ± 1.17
3.265AlaGlu: 3.265 ± 1.174
1.781AlaPhe: 1.781 ± 0.112
1.484AlaGly: 1.484 ± 0.159
0.594AlaHis: 0.594 ± 0.305
2.078AlaIle: 2.078 ± 1.027
1.781AlaLys: 1.781 ± 0.504
6.53AlaLeu: 6.53 ± 0.796
1.187AlaMet: 1.187 ± 0.61
0.594AlaAsn: 0.594 ± 0.367
1.484AlaPro: 1.484 ± 0.82
1.781AlaGln: 1.781 ± 0.994
1.781AlaArg: 1.781 ± 0.641
2.968AlaSer: 2.968 ± 0.874
0.0AlaThr: 0.0 ± 0.0
3.562AlaVal: 3.562 ± 1.008
0.297AlaTrp: 0.297 ± 0.459
2.078AlaTyr: 2.078 ± 0.735
0.0AlaXaa: 0.0 ± 0.0
Cys
1.484CysAla: 1.484 ± 0.478
0.297CysCys: 0.297 ± 0.721
2.078CysAsp: 2.078 ± 0.675
1.484CysGlu: 1.484 ± 0.763
2.671CysPhe: 2.671 ± 1.375
0.89CysGly: 0.89 ± 0.817
1.187CysHis: 1.187 ± 0.639
1.187CysIle: 1.187 ± 0.291
1.781CysLys: 1.781 ± 0.711
3.265CysLeu: 3.265 ± 1.239
0.594CysMet: 0.594 ± 0.331
1.781CysAsn: 1.781 ± 1.836
1.484CysPro: 1.484 ± 0.433
0.297CysGln: 0.297 ± 0.153
1.187CysArg: 1.187 ± 0.734
1.781CysSer: 1.781 ± 0.757
0.297CysThr: 0.297 ± 0.153
1.781CysVal: 1.781 ± 0.916
0.89CysTrp: 0.89 ± 1.697
0.89CysTyr: 0.89 ± 0.458
0.0CysXaa: 0.0 ± 0.0
Asp
2.078AspAla: 2.078 ± 0.96
2.078AspCys: 2.078 ± 0.215
4.156AspAsp: 4.156 ± 1.367
3.562AspGlu: 3.562 ± 0.666
2.671AspPhe: 2.671 ± 0.504
4.452AspGly: 4.452 ± 1.06
1.781AspHis: 1.781 ± 1.116
4.749AspIle: 4.749 ± 1.28
2.968AspLys: 2.968 ± 0.874
9.795AspLeu: 9.795 ± 2.638
1.187AspMet: 1.187 ± 0.351
2.375AspAsn: 2.375 ± 0.349
2.968AspPro: 2.968 ± 0.318
3.265AspGln: 3.265 ± 0.804
2.968AspArg: 2.968 ± 0.956
2.671AspSer: 2.671 ± 0.887
0.594AspThr: 0.594 ± 0.305
4.452AspVal: 4.452 ± 1.06
0.89AspTrp: 0.89 ± 0.325
1.187AspTyr: 1.187 ± 0.351
0.0AspXaa: 0.0 ± 0.0
Glu
4.156GluAla: 4.156 ± 1.259
1.781GluCys: 1.781 ± 0.601
4.452GluAsp: 4.452 ± 1.06
4.749GluGlu: 4.749 ± 0.78
3.265GluPhe: 3.265 ± 0.712
3.265GluGly: 3.265 ± 0.706
1.484GluHis: 1.484 ± 0.159
2.078GluIle: 2.078 ± 0.215
4.749GluLys: 4.749 ± 0.791
8.905GluLeu: 8.905 ± 0.749
1.781GluMet: 1.781 ± 0.529
1.484GluAsn: 1.484 ± 0.478
2.671GluPro: 2.671 ± 0.996
2.078GluGln: 2.078 ± 0.675
2.671GluArg: 2.671 ± 0.504
2.968GluSer: 2.968 ± 0.318
3.562GluThr: 3.562 ± 0.224
4.749GluVal: 4.749 ± 0.712
1.484GluTrp: 1.484 ± 0.677
2.078GluTyr: 2.078 ± 0.675
0.0GluXaa: 0.0 ± 0.0
Phe
1.781PheAla: 1.781 ± 0.759
0.89PheCys: 0.89 ± 0.325
2.078PheAsp: 2.078 ± 0.675
2.671PheGlu: 2.671 ± 0.365
2.671PhePhe: 2.671 ± 0.365
2.671PheGly: 2.671 ± 0.354
1.484PheHis: 1.484 ± 0.478
1.781PheIle: 1.781 ± 0.112
4.452PheLys: 4.452 ± 0.568
7.421PheLeu: 7.421 ± 1.678
1.781PheMet: 1.781 ± 0.546
2.968PheAsn: 2.968 ± 1.165
0.594PhePro: 0.594 ± 0.586
1.484PheGln: 1.484 ± 0.677
2.078PheArg: 2.078 ± 1.278
2.968PheSer: 2.968 ± 0.654
3.562PheThr: 3.562 ± 0.644
2.671PheVal: 2.671 ± 0.954
1.187PheTrp: 1.187 ± 0.734
1.187PheTyr: 1.187 ± 0.61
0.0PheXaa: 0.0 ± 0.0
Gly
1.187GlyAla: 1.187 ± 0.663
1.187GlyCys: 1.187 ± 0.734
2.968GlyAsp: 2.968 ± 0.956
4.452GlyGlu: 4.452 ± 0.568
4.452GlyPhe: 4.452 ± 1.06
2.671GlyGly: 2.671 ± 0.887
1.187GlyHis: 1.187 ± 0.291
2.375GlyIle: 2.375 ± 0.755
2.375GlyLys: 2.375 ± 0.996
6.233GlyLeu: 6.233 ± 0.514
1.187GlyMet: 1.187 ± 0.291
3.562GlyAsn: 3.562 ± 1.111
0.89GlyPro: 0.89 ± 0.458
2.671GlyGln: 2.671 ± 0.444
4.452GlyArg: 4.452 ± 2.017
5.343GlySer: 5.343 ± 1.303
1.781GlyThr: 1.781 ± 0.601
3.265GlyVal: 3.265 ± 1.075
0.594GlyTrp: 0.594 ± 0.586
1.187GlyTyr: 1.187 ± 0.291
0.0GlyXaa: 0.0 ± 0.0
His
0.297HisAla: 0.297 ± 0.153
0.89HisCys: 0.89 ± 0.723
0.594HisAsp: 0.594 ± 0.586
2.671HisGlu: 2.671 ± 0.365
0.297HisPhe: 0.297 ± 0.153
0.89HisGly: 0.89 ± 0.723
0.297HisHis: 0.297 ± 0.153
1.484HisIle: 1.484 ± 0.677
0.594HisLys: 0.594 ± 0.305
2.671HisLeu: 2.671 ± 0.365
0.594HisMet: 0.594 ± 0.292
0.89HisAsn: 0.89 ± 0.321
0.0HisPro: 0.0 ± 0.0
1.187HisGln: 1.187 ± 0.629
1.484HisArg: 1.484 ± 1.181
2.375HisSer: 2.375 ± 0.582
1.187HisThr: 1.187 ± 1.835
0.89HisVal: 0.89 ± 0.458
0.0HisTrp: 0.0 ± 0.0
0.89HisTyr: 0.89 ± 0.918
0.0HisXaa: 0.0 ± 0.0
Ile
2.968IleAla: 2.968 ± 0.832
1.781IleCys: 1.781 ± 1.116
3.265IleAsp: 3.265 ± 0.629
4.452IleGlu: 4.452 ± 0.884
1.484IlePhe: 1.484 ± 0.159
3.859IleGly: 3.859 ± 0.499
0.89IleHis: 0.89 ± 0.723
1.781IleIle: 1.781 ± 0.641
3.859IleLys: 3.859 ± 0.307
5.64IleLeu: 5.64 ± 1.256
2.671IleMet: 2.671 ± 0.649
2.968IleAsn: 2.968 ± 1.276
2.671IlePro: 2.671 ± 0.354
1.187IleGln: 1.187 ± 0.734
3.859IleArg: 3.859 ± 0.989
5.343IleSer: 5.343 ± 0.63
3.265IleThr: 3.265 ± 0.462
3.265IleVal: 3.265 ± 0.521
0.89IleTrp: 0.89 ± 0.437
1.484IleTyr: 1.484 ± 0.433
0.0IleXaa: 0.0 ± 0.0
Lys
1.781LysAla: 1.781 ± 0.574
1.781LysCys: 1.781 ± 1.116
4.452LysAsp: 4.452 ± 1.902
5.343LysGlu: 5.343 ± 1.164
3.265LysPhe: 3.265 ± 0.521
2.968LysGly: 2.968 ± 0.671
0.89LysHis: 0.89 ± 0.458
4.749LysIle: 4.749 ± 1.013
2.375LysLys: 2.375 ± 0.802
8.905LysLeu: 8.905 ± 1.967
0.89LysMet: 0.89 ± 0.458
4.156LysAsn: 4.156 ± 1.436
3.562LysPro: 3.562 ± 1.92
1.484LysGln: 1.484 ± 0.634
3.562LysArg: 3.562 ± 1.132
5.64LysSer: 5.64 ± 0.833
4.749LysThr: 4.749 ± 1.288
3.265LysVal: 3.265 ± 1.313
1.187LysTrp: 1.187 ± 0.351
2.375LysTyr: 2.375 ± 0.356
0.0LysXaa: 0.0 ± 0.0
Leu
4.452LeuAla: 4.452 ± 1.205
3.562LeuCys: 3.562 ± 1.422
8.608LeuAsp: 8.608 ± 2.213
6.827LeuGlu: 6.827 ± 1.298
4.452LeuPhe: 4.452 ± 0.432
6.233LeuGly: 6.233 ± 1.056
1.781LeuHis: 1.781 ± 0.546
10.982LeuIle: 10.982 ± 0.622
8.014LeuLys: 8.014 ± 0.947
11.279LeuLeu: 11.279 ± 2.034
4.156LeuMet: 4.156 ± 1.19
5.64LeuAsn: 5.64 ± 0.757
4.156LeuPro: 4.156 ± 1.915
3.265LeuGln: 3.265 ± 0.651
8.014LeuArg: 8.014 ± 1.354
11.576LeuSer: 11.576 ± 1.634
6.827LeuThr: 6.827 ± 0.772
6.53LeuVal: 6.53 ± 1.892
1.187LeuTrp: 1.187 ± 0.61
3.859LeuTyr: 3.859 ± 0.768
0.0LeuXaa: 0.0 ± 0.0
Met
1.484MetAla: 1.484 ± 0.478
0.594MetCys: 0.594 ± 0.305
0.89MetAsp: 0.89 ± 0.458
0.297MetGlu: 0.297 ± 0.404
1.187MetPhe: 1.187 ± 0.663
2.968MetGly: 2.968 ± 0.863
0.297MetHis: 0.297 ± 0.459
0.89MetIle: 0.89 ± 0.325
2.375MetLys: 2.375 ± 0.349
2.671MetLeu: 2.671 ± 1.888
1.187MetMet: 1.187 ± 0.61
0.89MetAsn: 0.89 ± 0.321
0.594MetPro: 0.594 ± 0.331
0.297MetGln: 0.297 ± 0.459
1.484MetArg: 1.484 ± 0.763
2.671MetSer: 2.671 ± 0.504
1.781MetThr: 1.781 ± 0.601
2.375MetVal: 2.375 ± 0.356
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.781AsnAla: 1.781 ± 0.574
1.187AsnCys: 1.187 ± 1.321
2.078AsnAsp: 2.078 ± 1.068
2.375AsnGlu: 2.375 ± 0.996
2.078AsnPhe: 2.078 ± 0.735
2.968AsnGly: 2.968 ± 1.119
1.187AsnHis: 1.187 ± 0.832
2.968AsnIle: 2.968 ± 1.372
3.562AsnLys: 3.562 ± 1.148
8.608AsnLeu: 8.608 ± 0.889
1.484AsnMet: 1.484 ± 0.634
2.078AsnAsn: 2.078 ± 0.85
1.187AsnPro: 1.187 ± 0.377
3.562AsnGln: 3.562 ± 0.224
2.375AsnArg: 2.375 ± 0.636
2.968AsnSer: 2.968 ± 1.308
3.859AsnThr: 3.859 ± 0.902
3.265AsnVal: 3.265 ± 0.486
0.0AsnTrp: 0.0 ± 0.0
1.187AsnTyr: 1.187 ± 0.351
0.0AsnXaa: 0.0 ± 0.0
Pro
1.187ProAla: 1.187 ± 1.124
1.187ProCys: 1.187 ± 0.351
2.375ProAsp: 2.375 ± 0.987
2.078ProGlu: 2.078 ± 0.215
1.484ProPhe: 1.484 ± 0.763
2.078ProGly: 2.078 ± 1.168
1.187ProHis: 1.187 ± 0.757
2.078ProIle: 2.078 ± 0.466
3.265ProLys: 3.265 ± 0.651
3.859ProLeu: 3.859 ± 1.677
0.297ProMet: 0.297 ± 0.459
2.078ProAsn: 2.078 ± 1.379
0.89ProPro: 0.89 ± 1.072
1.187ProGln: 1.187 ± 0.629
0.89ProArg: 0.89 ± 0.437
3.265ProSer: 3.265 ± 1.602
2.968ProThr: 2.968 ± 1.308
2.078ProVal: 2.078 ± 0.735
0.0ProTrp: 0.0 ± 0.0
1.484ProTyr: 1.484 ± 0.625
0.0ProXaa: 0.0 ± 0.0
Gln
1.187GlnAla: 1.187 ± 0.955
0.89GlnCys: 0.89 ± 0.325
1.781GlnAsp: 1.781 ± 0.546
2.671GlnGlu: 2.671 ± 0.824
2.375GlnPhe: 2.375 ± 0.349
3.265GlnGly: 3.265 ± 0.651
0.594GlnHis: 0.594 ± 0.586
2.968GlnIle: 2.968 ± 0.52
2.671GlnLys: 2.671 ± 0.534
2.968GlnLeu: 2.968 ± 0.418
0.297GlnMet: 0.297 ± 0.153
0.594GlnAsn: 0.594 ± 0.586
0.89GlnPro: 0.89 ± 0.437
1.484GlnGln: 1.484 ± 0.478
2.078GlnArg: 2.078 ± 0.735
2.968GlnSer: 2.968 ± 0.671
0.594GlnThr: 0.594 ± 0.331
4.156GlnVal: 4.156 ± 1.367
0.0GlnTrp: 0.0 ± 0.0
0.594GlnTyr: 0.594 ± 0.331
0.0GlnXaa: 0.0 ± 0.0
Arg
1.781ArgAla: 1.781 ± 0.112
1.187ArgCys: 1.187 ± 1.816
2.375ArgAsp: 2.375 ± 0.755
3.562ArgGlu: 3.562 ± 0.598
3.265ArgPhe: 3.265 ± 0.973
1.781ArgGly: 1.781 ± 0.65
1.187ArgHis: 1.187 ± 0.291
0.89ArgIle: 0.89 ± 0.458
3.859ArgLys: 3.859 ± 1.948
6.827ArgLeu: 6.827 ± 0.923
0.0ArgMet: 0.0 ± 0.0
4.156ArgAsn: 4.156 ± 0.956
2.078ArgPro: 2.078 ± 0.96
1.187ArgGln: 1.187 ± 0.351
2.968ArgArg: 2.968 ± 0.52
6.233ArgSer: 6.233 ± 0.882
3.859ArgThr: 3.859 ± 1.514
3.562ArgVal: 3.562 ± 0.67
1.484ArgTrp: 1.484 ± 0.159
2.375ArgTyr: 2.375 ± 0.954
0.0ArgXaa: 0.0 ± 0.0
Ser
2.078SerAla: 2.078 ± 0.621
2.375SerCys: 2.375 ± 0.702
8.311SerAsp: 8.311 ± 0.535
5.64SerGlu: 5.64 ± 2.529
2.671SerPhe: 2.671 ± 0.365
4.749SerGly: 4.749 ± 0.483
2.375SerHis: 2.375 ± 0.39
5.046SerIle: 5.046 ± 0.66
5.936SerLys: 5.936 ± 1.913
9.202SerLeu: 9.202 ± 0.311
2.968SerMet: 2.968 ± 0.418
4.452SerAsn: 4.452 ± 1.17
3.265SerPro: 3.265 ± 1.05
2.375SerGln: 2.375 ± 0.802
4.749SerArg: 4.749 ± 0.483
8.905SerSer: 8.905 ± 1.796
2.671SerThr: 2.671 ± 0.773
5.936SerVal: 5.936 ± 1.307
0.594SerTrp: 0.594 ± 0.586
2.375SerTyr: 2.375 ± 0.356
0.0SerXaa: 0.0 ± 0.0
Thr
2.078ThrAla: 2.078 ± 0.621
1.484ThrCys: 1.484 ± 0.681
2.078ThrAsp: 2.078 ± 0.466
2.968ThrGlu: 2.968 ± 0.418
2.671ThrPhe: 2.671 ± 0.773
2.671ThrGly: 2.671 ± 1.373
0.594ThrHis: 0.594 ± 0.918
2.968ThrIle: 2.968 ± 1.25
4.452ThrLys: 4.452 ± 0.477
5.936ThrLeu: 5.936 ± 1.055
0.594ThrMet: 0.594 ± 0.331
2.968ThrAsn: 2.968 ± 0.402
2.078ThrPro: 2.078 ± 0.675
2.375ThrGln: 2.375 ± 0.987
2.078ThrArg: 2.078 ± 1.546
4.749ThrSer: 4.749 ± 0.413
1.187ThrThr: 1.187 ± 0.377
2.078ThrVal: 2.078 ± 1.168
0.297ThrTrp: 0.297 ± 0.153
0.594ThrTyr: 0.594 ± 0.305
0.0ThrXaa: 0.0 ± 0.0
Val
3.265ValAla: 3.265 ± 0.7
1.484ValCys: 1.484 ± 0.763
3.562ValAsp: 3.562 ± 0.644
4.749ValGlu: 4.749 ± 2.062
2.671ValPhe: 2.671 ± 0.975
2.671ValGly: 2.671 ± 0.504
0.594ValHis: 0.594 ± 0.918
4.452ValIle: 4.452 ± 1.434
6.53ValLys: 6.53 ± 1.657
6.53ValLeu: 6.53 ± 1.197
0.89ValMet: 0.89 ± 0.458
5.64ValAsn: 5.64 ± 1.634
2.671ValPro: 2.671 ± 0.996
2.671ValGln: 2.671 ± 1.288
4.156ValArg: 4.156 ± 1.471
5.936ValSer: 5.936 ± 1.307
1.781ValThr: 1.781 ± 0.546
3.265ValVal: 3.265 ± 0.804
0.89ValTrp: 0.89 ± 0.723
1.187ValTyr: 1.187 ± 0.61
0.0ValXaa: 0.0 ± 0.0
Trp
0.594TrpAla: 0.594 ± 0.305
0.0TrpCys: 0.0 ± 0.0
1.484TrpAsp: 1.484 ± 1.133
0.0TrpGlu: 0.0 ± 0.0
0.594TrpPhe: 0.594 ± 0.661
0.594TrpGly: 0.594 ± 0.305
0.594TrpHis: 0.594 ± 0.367
0.594TrpIle: 0.594 ± 0.918
0.594TrpLys: 0.594 ± 0.661
1.187TrpLeu: 1.187 ± 0.377
0.594TrpMet: 0.594 ± 0.918
0.0TrpAsn: 0.0 ± 0.0
0.89TrpPro: 0.89 ± 0.437
0.0TrpGln: 0.0 ± 0.0
0.297TrpArg: 0.297 ± 0.459
0.89TrpSer: 0.89 ± 0.817
0.297TrpThr: 0.297 ± 0.404
2.078TrpVal: 2.078 ± 0.675
0.297TrpTrp: 0.297 ± 0.459
0.594TrpTyr: 0.594 ± 0.367
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.297TyrAla: 0.297 ± 0.153
1.781TyrCys: 1.781 ± 0.65
1.484TyrAsp: 1.484 ± 0.763
0.594TyrGlu: 0.594 ± 0.331
2.375TyrPhe: 2.375 ± 1.221
0.89TyrGly: 0.89 ± 0.918
0.0TyrHis: 0.0 ± 0.0
1.484TyrIle: 1.484 ± 0.634
1.187TyrLys: 1.187 ± 0.377
3.265TyrLeu: 3.265 ± 1.269
0.297TyrMet: 0.297 ± 0.404
1.484TyrAsn: 1.484 ± 0.82
0.89TyrPro: 0.89 ± 0.321
1.187TyrGln: 1.187 ± 0.377
1.484TyrArg: 1.484 ± 0.677
4.452TyrSer: 4.452 ± 1.841
2.078TyrThr: 2.078 ± 0.215
2.375TyrVal: 2.375 ± 0.356
0.0TyrTrp: 0.0 ± 0.0
0.297TyrTyr: 0.297 ± 0.153
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3370 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski