Amino acid dipepetide frequency for Tomato leaf curl Moheli virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.032AlaAla: 4.032 ± 1.836
1.344AlaCys: 1.344 ± 0.956
1.344AlaAsp: 1.344 ± 0.956
0.0AlaGlu: 0.0 ± 0.0
0.0AlaPhe: 0.0 ± 0.0
0.0AlaGly: 0.0 ± 0.0
1.344AlaHis: 1.344 ± 1.369
2.688AlaIle: 2.688 ± 2.738
2.688AlaLys: 2.688 ± 1.328
4.032AlaLeu: 4.032 ± 1.936
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
5.376AlaPro: 5.376 ± 2.727
4.032AlaGln: 4.032 ± 2.864
2.688AlaArg: 2.688 ± 2.738
6.72AlaSer: 6.72 ± 1.452
5.376AlaThr: 5.376 ± 2.839
6.72AlaVal: 6.72 ± 2.697
0.0AlaTrp: 0.0 ± 0.0
1.344AlaTyr: 1.344 ± 1.417
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
2.688CysCys: 2.688 ± 2.738
0.0CysAsp: 0.0 ± 0.0
1.344CysGlu: 1.344 ± 0.956
1.344CysPhe: 1.344 ± 1.376
1.344CysGly: 1.344 ± 1.401
0.0CysHis: 0.0 ± 0.0
1.344CysIle: 1.344 ± 1.401
1.344CysLys: 1.344 ± 0.956
0.0CysLeu: 0.0 ± 0.0
2.688CysMet: 2.688 ± 1.638
0.0CysAsn: 0.0 ± 0.0
2.688CysPro: 2.688 ± 2.738
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
4.032CysSer: 4.032 ± 4.203
1.344CysThr: 1.344 ± 0.956
2.688CysVal: 2.688 ± 1.911
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
1.344AspCys: 1.344 ± 1.401
2.688AspAsp: 2.688 ± 1.402
2.688AspGlu: 2.688 ± 1.328
2.688AspPhe: 2.688 ± 1.311
0.0AspGly: 0.0 ± 0.0
2.688AspHis: 2.688 ± 1.622
2.688AspIle: 2.688 ± 1.311
1.344AspLys: 1.344 ± 1.401
5.376AspLeu: 5.376 ± 1.455
0.0AspMet: 0.0 ± 0.0
2.688AspAsn: 2.688 ± 1.402
2.688AspPro: 2.688 ± 2.738
0.0AspGln: 0.0 ± 0.0
4.032AspArg: 4.032 ± 1.836
5.376AspSer: 5.376 ± 1.854
1.344AspThr: 1.344 ± 1.401
8.065AspVal: 8.065 ± 3.006
1.344AspTrp: 1.344 ± 1.401
2.688AspTyr: 2.688 ± 1.835
0.0AspXaa: 0.0 ± 0.0
Glu
2.688GluAla: 2.688 ± 1.453
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
1.344GluGlu: 1.344 ± 1.401
1.344GluPhe: 1.344 ± 1.369
5.376GluGly: 5.376 ± 1.455
0.0GluHis: 0.0 ± 0.0
2.688GluIle: 2.688 ± 2.752
0.0GluLys: 0.0 ± 0.0
8.065GluLeu: 8.065 ± 3.283
0.0GluMet: 0.0 ± 0.0
8.065GluAsn: 8.065 ± 2.943
4.032GluPro: 4.032 ± 1.577
4.032GluGln: 4.032 ± 2.043
0.0GluArg: 0.0 ± 0.0
2.688GluSer: 2.688 ± 2.834
1.344GluThr: 1.344 ± 1.417
0.0GluVal: 0.0 ± 0.0
1.344GluTrp: 1.344 ± 1.401
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.344PheCys: 1.344 ± 0.956
2.688PheAsp: 2.688 ± 1.911
1.344PheGlu: 1.344 ± 1.369
2.688PhePhe: 2.688 ± 1.911
1.344PheGly: 1.344 ± 0.956
2.688PheHis: 2.688 ± 1.453
1.344PheIle: 1.344 ± 1.376
2.688PheLys: 2.688 ± 1.311
5.376PheLeu: 5.376 ± 2.17
0.0PheMet: 0.0 ± 0.0
6.72PheAsn: 6.72 ± 4.016
1.344PhePro: 1.344 ± 1.369
1.344PheGln: 1.344 ± 1.401
6.72PheArg: 6.72 ± 4.27
2.688PheSer: 2.688 ± 2.802
1.344PheThr: 1.344 ± 0.956
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
1.344PheTyr: 1.344 ± 0.956
0.0PheXaa: 0.0 ± 0.0
Gly
2.688GlyAla: 2.688 ± 1.453
2.688GlyCys: 2.688 ± 1.328
4.032GlyAsp: 4.032 ± 3.068
2.688GlyGlu: 2.688 ± 2.007
2.688GlyPhe: 2.688 ± 1.835
1.344GlyGly: 1.344 ± 0.956
1.344GlyHis: 1.344 ± 1.369
5.376GlyIle: 5.376 ± 1.371
2.688GlyLys: 2.688 ± 1.911
2.688GlyLeu: 2.688 ± 1.622
1.344GlyMet: 1.344 ± 0.956
2.688GlyAsn: 2.688 ± 1.402
4.032GlyPro: 4.032 ± 2.867
1.344GlyGln: 1.344 ± 0.956
0.0GlyArg: 0.0 ± 0.0
1.344GlySer: 1.344 ± 1.417
4.032GlyThr: 4.032 ± 2.557
2.688GlyVal: 2.688 ± 2.752
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
5.376HisAla: 5.376 ± 1.854
4.032HisCys: 4.032 ± 2.964
1.344HisAsp: 1.344 ± 1.376
4.032HisGlu: 4.032 ± 2.864
1.344HisPhe: 1.344 ± 1.369
2.688HisGly: 2.688 ± 1.835
2.688HisHis: 2.688 ± 2.802
2.688HisIle: 2.688 ± 2.802
2.688HisLys: 2.688 ± 1.773
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.344HisAsn: 1.344 ± 1.376
0.0HisPro: 0.0 ± 0.0
1.344HisGln: 1.344 ± 0.956
4.032HisArg: 4.032 ± 2.557
0.0HisSer: 0.0 ± 0.0
4.032HisThr: 4.032 ± 2.867
4.032HisVal: 4.032 ± 1.514
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.032IleAla: 4.032 ± 3.09
1.344IleCys: 1.344 ± 1.417
4.032IleAsp: 4.032 ± 2.7
1.344IleGlu: 1.344 ± 1.369
0.0IlePhe: 0.0 ± 0.0
1.344IleGly: 1.344 ± 0.956
1.344IleHis: 1.344 ± 1.376
5.376IleIle: 5.376 ± 2.622
5.376IleLys: 5.376 ± 1.201
1.344IleLeu: 1.344 ± 0.956
1.344IleMet: 1.344 ± 1.183
4.032IleAsn: 4.032 ± 1.158
1.344IlePro: 1.344 ± 1.401
4.032IleGln: 4.032 ± 2.7
6.72IleArg: 6.72 ± 3.155
6.72IleSer: 6.72 ± 2.045
2.688IleThr: 2.688 ± 1.311
2.688IleVal: 2.688 ± 1.911
4.032IleTrp: 4.032 ± 1.703
4.032IleTyr: 4.032 ± 1.836
0.0IleXaa: 0.0 ± 0.0
Lys
1.344LysAla: 1.344 ± 1.369
1.344LysCys: 1.344 ± 1.376
0.0LysAsp: 0.0 ± 0.0
4.032LysGlu: 4.032 ± 1.703
2.688LysPhe: 2.688 ± 1.311
2.688LysGly: 2.688 ± 1.328
1.344LysHis: 1.344 ± 0.956
6.72LysIle: 6.72 ± 2.06
2.688LysLys: 2.688 ± 1.328
1.344LysLeu: 1.344 ± 1.417
0.0LysMet: 0.0 ± 0.0
2.688LysAsn: 2.688 ± 1.311
2.688LysPro: 2.688 ± 1.453
2.688LysGln: 2.688 ± 1.453
5.376LysArg: 5.376 ± 2.615
2.688LysSer: 2.688 ± 1.328
0.0LysThr: 0.0 ± 0.0
5.376LysVal: 5.376 ± 1.854
0.0LysTrp: 0.0 ± 0.0
4.032LysTyr: 4.032 ± 1.514
0.0LysXaa: 0.0 ± 0.0
Leu
1.344LeuAla: 1.344 ± 1.369
0.0LeuCys: 0.0 ± 0.0
4.032LeuAsp: 4.032 ± 2.7
2.688LeuGlu: 2.688 ± 1.936
2.688LeuPhe: 2.688 ± 2.007
8.065LeuGly: 8.065 ± 2.017
1.344LeuHis: 1.344 ± 1.401
5.376LeuIle: 5.376 ± 2.806
5.376LeuLys: 5.376 ± 2.17
6.72LeuLeu: 6.72 ± 2.446
0.0LeuMet: 0.0 ± 0.0
4.032LeuAsn: 4.032 ± 1.514
0.0LeuPro: 0.0 ± 0.0
5.376LeuGln: 5.376 ± 2.029
6.72LeuArg: 6.72 ± 2.479
2.688LeuSer: 2.688 ± 2.834
5.376LeuThr: 5.376 ± 4.401
2.688LeuVal: 2.688 ± 1.911
0.0LeuTrp: 0.0 ± 0.0
4.032LeuTyr: 4.032 ± 2.513
0.0LeuXaa: 0.0 ± 0.0
Met
1.344MetAla: 1.344 ± 0.956
0.0MetCys: 0.0 ± 0.0
6.72MetAsp: 6.72 ± 1.513
0.0MetGlu: 0.0 ± 0.0
4.032MetPhe: 4.032 ± 1.841
1.344MetGly: 1.344 ± 1.417
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.344MetLys: 1.344 ± 0.956
1.344MetLeu: 1.344 ± 1.369
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.688MetPro: 2.688 ± 2.007
0.0MetGln: 0.0 ± 0.0
1.344MetArg: 1.344 ± 1.401
1.344MetSer: 1.344 ± 0.956
1.344MetThr: 1.344 ± 1.417
0.0MetVal: 0.0 ± 0.0
1.344MetTrp: 1.344 ± 1.369
4.032MetTyr: 4.032 ± 2.867
0.0MetXaa: 0.0 ± 0.0
Asn
1.344AsnAla: 1.344 ± 0.956
1.344AsnCys: 1.344 ± 1.401
2.688AsnAsp: 2.688 ± 1.311
2.688AsnGlu: 2.688 ± 1.453
2.688AsnPhe: 2.688 ± 1.311
0.0AsnGly: 0.0 ± 0.0
8.065AsnHis: 8.065 ± 2.803
2.688AsnIle: 2.688 ± 1.311
0.0AsnLys: 0.0 ± 0.0
2.688AsnLeu: 2.688 ± 2.007
4.032AsnMet: 4.032 ± 1.749
1.344AsnAsn: 1.344 ± 1.417
2.688AsnPro: 2.688 ± 1.311
2.688AsnGln: 2.688 ± 1.402
1.344AsnArg: 1.344 ± 1.376
4.032AsnSer: 4.032 ± 2.653
2.688AsnThr: 2.688 ± 1.773
2.688AsnVal: 2.688 ± 1.773
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.032ProAla: 4.032 ± 1.936
2.688ProCys: 2.688 ± 1.453
5.376ProAsp: 5.376 ± 2.639
0.0ProGlu: 0.0 ± 0.0
2.688ProPhe: 2.688 ± 1.311
2.688ProGly: 2.688 ± 1.911
2.688ProHis: 2.688 ± 1.773
4.032ProIle: 4.032 ± 1.61
2.688ProLys: 2.688 ± 1.402
5.376ProLeu: 5.376 ± 3.005
5.376ProMet: 5.376 ± 1.751
1.344ProAsn: 1.344 ± 1.369
0.0ProPro: 0.0 ± 0.0
2.688ProGln: 2.688 ± 1.622
5.376ProArg: 5.376 ± 2.606
5.376ProSer: 5.376 ± 2.655
4.032ProThr: 4.032 ± 3.09
5.376ProVal: 5.376 ± 1.455
0.0ProTrp: 0.0 ± 0.0
1.344ProTyr: 1.344 ± 0.956
0.0ProXaa: 0.0 ± 0.0
Gln
8.065GlnAla: 8.065 ± 2.861
0.0GlnCys: 0.0 ± 0.0
2.688GlnAsp: 2.688 ± 1.835
2.688GlnGlu: 2.688 ± 1.402
0.0GlnPhe: 0.0 ± 0.0
1.344GlnGly: 1.344 ± 1.401
2.688GlnHis: 2.688 ± 2.802
2.688GlnIle: 2.688 ± 1.622
1.344GlnLys: 1.344 ± 1.369
2.688GlnLeu: 2.688 ± 2.802
1.344GlnMet: 1.344 ± 1.401
4.032GlnAsn: 4.032 ± 1.514
6.72GlnPro: 6.72 ± 2.728
0.0GlnGln: 0.0 ± 0.0
2.688GlnArg: 2.688 ± 1.402
2.688GlnSer: 2.688 ± 1.311
4.032GlnThr: 4.032 ± 2.853
6.72GlnVal: 6.72 ± 3.044
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
6.72ArgAla: 6.72 ± 1.094
2.688ArgCys: 2.688 ± 1.453
6.72ArgAsp: 6.72 ± 3.414
2.688ArgGlu: 2.688 ± 1.936
5.376ArgPhe: 5.376 ± 1.807
2.688ArgGly: 2.688 ± 1.328
2.688ArgHis: 2.688 ± 1.835
4.032ArgIle: 4.032 ± 2.557
4.032ArgLys: 4.032 ± 1.836
4.032ArgLeu: 4.032 ± 1.703
2.688ArgMet: 2.688 ± 1.911
0.0ArgAsn: 0.0 ± 0.0
8.065ArgPro: 8.065 ± 2.359
1.344ArgGln: 1.344 ± 1.369
12.097ArgArg: 12.097 ± 4.568
4.032ArgSer: 4.032 ± 1.936
4.032ArgThr: 4.032 ± 3.137
5.376ArgVal: 5.376 ± 2.17
0.0ArgTrp: 0.0 ± 0.0
2.688ArgTyr: 2.688 ± 1.453
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
2.688SerAsp: 2.688 ± 1.328
1.344SerGlu: 1.344 ± 1.376
2.688SerPhe: 2.688 ± 1.936
4.032SerGly: 4.032 ± 1.703
4.032SerHis: 4.032 ± 2.557
5.376SerIle: 5.376 ± 1.896
5.376SerLys: 5.376 ± 2.906
1.344SerLeu: 1.344 ± 1.417
1.344SerMet: 1.344 ± 2.617
1.344SerAsn: 1.344 ± 0.956
9.409SerPro: 9.409 ± 4.184
6.72SerGln: 6.72 ± 4.165
5.376SerArg: 5.376 ± 2.804
8.065SerSer: 8.065 ± 4.778
6.72SerThr: 6.72 ± 2.588
5.376SerVal: 5.376 ± 4.11
1.344SerTrp: 1.344 ± 0.956
2.688SerTyr: 2.688 ± 1.328
0.0SerXaa: 0.0 ± 0.0
Thr
4.032ThrAla: 4.032 ± 1.158
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
4.032ThrGlu: 4.032 ± 1.61
0.0ThrPhe: 0.0 ± 0.0
5.376ThrGly: 5.376 ± 2.17
4.032ThrHis: 4.032 ± 1.841
2.688ThrIle: 2.688 ± 1.936
1.344ThrLys: 1.344 ± 1.401
5.376ThrLeu: 5.376 ± 1.507
0.0ThrMet: 0.0 ± 0.0
1.344ThrAsn: 1.344 ± 0.956
5.376ThrPro: 5.376 ± 4.015
4.032ThrGln: 4.032 ± 3.191
4.032ThrArg: 4.032 ± 1.401
8.065ThrSer: 8.065 ± 0.321
0.0ThrThr: 0.0 ± 0.0
2.688ThrVal: 2.688 ± 1.911
0.0ThrTrp: 0.0 ± 0.0
5.376ThrTyr: 5.376 ± 1.752
0.0ThrXaa: 0.0 ± 0.0
Val
1.344ValAla: 1.344 ± 1.417
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
2.688ValGlu: 2.688 ± 2.738
5.376ValPhe: 5.376 ± 2.17
2.688ValGly: 2.688 ± 1.911
1.344ValHis: 1.344 ± 1.369
4.032ValIle: 4.032 ± 2.864
5.376ValLys: 5.376 ± 3.822
5.376ValLeu: 5.376 ± 3.833
2.688ValMet: 2.688 ± 1.453
0.0ValAsn: 0.0 ± 0.0
4.032ValPro: 4.032 ± 2.867
8.065ValGln: 8.065 ± 3.59
5.376ValArg: 5.376 ± 2.615
6.72ValSer: 6.72 ± 2.503
2.688ValThr: 2.688 ± 1.911
2.688ValVal: 2.688 ± 1.911
1.344ValTrp: 1.344 ± 1.376
5.376ValTyr: 5.376 ± 1.201
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.344TrpAsp: 1.344 ± 1.369
1.344TrpGlu: 1.344 ± 1.376
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.344TrpMet: 1.344 ± 0.956
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.344TrpArg: 1.344 ± 1.401
1.344TrpSer: 1.344 ± 1.401
4.032TrpThr: 4.032 ± 1.703
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.344TyrAla: 1.344 ± 0.956
0.0TyrCys: 0.0 ± 0.0
1.344TyrAsp: 1.344 ± 0.956
4.032TyrGlu: 4.032 ± 2.043
2.688TyrPhe: 2.688 ± 1.311
1.344TyrGly: 1.344 ± 0.956
1.344TyrHis: 1.344 ± 1.376
1.344TyrIle: 1.344 ± 0.956
1.344TyrLys: 1.344 ± 1.417
5.376TyrLeu: 5.376 ± 2.756
2.688TyrMet: 2.688 ± 1.2
4.032TyrAsn: 4.032 ± 1.514
0.0TyrPro: 0.0 ± 0.0
2.688TyrGln: 2.688 ± 1.453
6.72TyrArg: 6.72 ± 3.481
0.0TyrSer: 0.0 ± 0.0
1.344TyrThr: 1.344 ± 1.417
1.344TyrVal: 1.344 ± 1.369
0.0TyrTrp: 0.0 ± 0.0
1.344TyrTyr: 1.344 ± 1.401
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (745 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski