Amino acid dipepetide frequency for Thermanaerovibrio acidaminovorans (strain ATCC 49978 / DSM 6589 / Su883) (Selenomonas acidaminovorans)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.137AlaAla: 8.137 ± 0.174
1.212AlaCys: 1.212 ± 0.051
3.59AlaAsp: 3.59 ± 0.076
5.465AlaGlu: 5.465 ± 0.121
3.936AlaPhe: 3.936 ± 0.085
6.885AlaGly: 6.885 ± 0.127
1.552AlaHis: 1.552 ± 0.048
4.534AlaIle: 4.534 ± 0.099
3.484AlaLys: 3.484 ± 0.082
11.904AlaLeu: 11.904 ± 0.176
3.687AlaMet: 3.687 ± 0.081
1.852AlaAsn: 1.852 ± 0.068
3.143AlaPro: 3.143 ± 0.088
2.867AlaGln: 2.867 ± 0.08
6.559AlaArg: 6.559 ± 0.119
6.119AlaSer: 6.119 ± 0.12
2.914AlaThr: 2.914 ± 0.077
7.8AlaVal: 7.8 ± 0.129
0.877AlaTrp: 0.877 ± 0.038
2.099AlaTyr: 2.099 ± 0.064
0.0AlaXaa: 0.0 ± 0.0
Cys
1.111CysAla: 1.111 ± 0.046
0.196CysCys: 0.196 ± 0.019
0.647CysAsp: 0.647 ± 0.034
0.602CysGlu: 0.602 ± 0.029
0.464CysPhe: 0.464 ± 0.031
1.656CysGly: 1.656 ± 0.069
0.332CysHis: 0.332 ± 0.026
0.439CysIle: 0.439 ± 0.025
0.273CysLys: 0.273 ± 0.022
1.39CysLeu: 1.39 ± 0.051
0.254CysMet: 0.254 ± 0.018
0.273CysAsn: 0.273 ± 0.022
0.942CysPro: 0.942 ± 0.049
0.372CysGln: 0.372 ± 0.027
0.975CysArg: 0.975 ± 0.037
0.889CysSer: 0.889 ± 0.04
0.473CysThr: 0.473 ± 0.029
0.951CysVal: 0.951 ± 0.043
0.145CysTrp: 0.145 ± 0.016
0.272CysTyr: 0.272 ± 0.025
0.0CysXaa: 0.0 ± 0.0
Asp
3.736AspAla: 3.736 ± 0.069
0.503AspCys: 0.503 ± 0.028
2.17AspAsp: 2.17 ± 0.069
2.902AspGlu: 2.902 ± 0.076
1.96AspPhe: 1.96 ± 0.057
4.925AspGly: 4.925 ± 0.116
1.277AspHis: 1.277 ± 0.051
1.979AspIle: 1.979 ± 0.073
1.533AspLys: 1.533 ± 0.062
7.652AspLeu: 7.652 ± 0.131
1.611AspMet: 1.611 ± 0.049
1.005AspAsn: 1.005 ± 0.049
4.006AspPro: 4.006 ± 0.094
2.328AspGln: 2.328 ± 0.063
5.569AspArg: 5.569 ± 0.109
2.544AspSer: 2.544 ± 0.073
1.586AspThr: 1.586 ± 0.049
4.638AspVal: 4.638 ± 0.094
0.7AspTrp: 0.7 ± 0.032
1.24AspTyr: 1.24 ± 0.056
0.0AspXaa: 0.0 ± 0.0
Glu
8.277GluAla: 8.277 ± 0.135
0.492GluCys: 0.492 ± 0.027
4.384GluAsp: 4.384 ± 0.09
6.853GluGlu: 6.853 ± 0.149
1.743GluPhe: 1.743 ± 0.059
6.883GluGly: 6.883 ± 0.119
1.074GluHis: 1.074 ± 0.038
3.44GluIle: 3.44 ± 0.078
1.937GluLys: 1.937 ± 0.072
6.724GluLeu: 6.724 ± 0.116
2.445GluMet: 2.445 ± 0.066
1.351GluAsn: 1.351 ± 0.053
2.321GluPro: 2.321 ± 0.061
1.399GluGln: 1.399 ± 0.058
5.569GluArg: 5.569 ± 0.139
2.807GluSer: 2.807 ± 0.082
2.099GluThr: 2.099 ± 0.06
6.333GluVal: 6.333 ± 0.115
0.586GluTrp: 0.586 ± 0.033
1.076GluTyr: 1.076 ± 0.043
0.0GluXaa: 0.0 ± 0.0
Phe
2.844PheAla: 2.844 ± 0.075
0.49PheCys: 0.49 ± 0.028
2.078PheAsp: 2.078 ± 0.06
2.085PheGlu: 2.085 ± 0.057
1.411PhePhe: 1.411 ± 0.059
3.269PheGly: 3.269 ± 0.092
0.778PheHis: 0.778 ± 0.035
1.57PheIle: 1.57 ± 0.061
1.422PheLys: 1.422 ± 0.05
3.883PheLeu: 3.883 ± 0.086
1.051PheMet: 1.051 ± 0.046
0.981PheAsn: 0.981 ± 0.048
1.826PhePro: 1.826 ± 0.058
1.214PheGln: 1.214 ± 0.047
2.542PheArg: 2.542 ± 0.066
2.355PheSer: 2.355 ± 0.072
1.473PheThr: 1.473 ± 0.051
2.919PheVal: 2.919 ± 0.079
0.436PheTrp: 0.436 ± 0.028
0.827PheTyr: 0.827 ± 0.045
0.0PheXaa: 0.0 ± 0.0
Gly
9.123GlyAla: 9.123 ± 0.169
1.346GlyCys: 1.346 ± 0.056
5.507GlyAsp: 5.507 ± 0.101
6.209GlyGlu: 6.209 ± 0.101
3.526GlyPhe: 3.526 ± 0.087
8.832GlyGly: 8.832 ± 0.166
1.798GlyHis: 1.798 ± 0.058
5.363GlyIle: 5.363 ± 0.12
3.406GlyLys: 3.406 ± 0.092
10.282GlyLeu: 10.282 ± 0.164
3.041GlyMet: 3.041 ± 0.069
2.062GlyAsn: 2.062 ± 0.06
3.805GlyPro: 3.805 ± 0.1
2.281GlyGln: 2.281 ± 0.057
7.068GlyArg: 7.068 ± 0.148
5.61GlySer: 5.61 ± 0.114
4.23GlyThr: 4.23 ± 0.101
8.379GlyVal: 8.379 ± 0.141
1.284GlyTrp: 1.284 ± 0.056
2.597GlyTyr: 2.597 ± 0.066
0.0GlyXaa: 0.0 ± 0.0
His
1.094HisAla: 1.094 ± 0.049
0.293HisCys: 0.293 ± 0.025
0.744HisAsp: 0.744 ± 0.039
0.778HisGlu: 0.778 ± 0.041
0.616HisPhe: 0.616 ± 0.029
1.736HisGly: 1.736 ± 0.064
0.55HisHis: 0.55 ± 0.035
0.757HisIle: 0.757 ± 0.037
0.436HisLys: 0.436 ± 0.031
2.48HisLeu: 2.48 ± 0.066
0.573HisMet: 0.573 ± 0.033
0.406HisAsn: 0.406 ± 0.027
1.371HisPro: 1.371 ± 0.054
0.716HisGln: 0.716 ± 0.037
1.909HisArg: 1.909 ± 0.066
0.87HisSer: 0.87 ± 0.037
0.639HisThr: 0.639 ± 0.039
1.517HisVal: 1.517 ± 0.058
0.268HisTrp: 0.268 ± 0.024
0.385HisTyr: 0.385 ± 0.029
0.0HisXaa: 0.0 ± 0.0
Ile
3.766IleAla: 3.766 ± 0.107
0.721IleCys: 0.721 ± 0.035
2.417IleAsp: 2.417 ± 0.074
2.57IleGlu: 2.57 ± 0.078
1.602IlePhe: 1.602 ± 0.056
4.211IleGly: 4.211 ± 0.083
0.871IleHis: 0.871 ± 0.043
1.974IleIle: 1.974 ± 0.068
1.85IleLys: 1.85 ± 0.057
5.271IleLeu: 5.271 ± 0.106
1.394IleMet: 1.394 ± 0.051
1.148IleAsn: 1.148 ± 0.053
3.031IlePro: 3.031 ± 0.079
1.461IleGln: 1.461 ± 0.051
4.211IleArg: 4.211 ± 0.081
3.468IleSer: 3.468 ± 0.077
2.239IleThr: 2.239 ± 0.053
3.02IleVal: 3.02 ± 0.074
0.616IleTrp: 0.616 ± 0.033
1.173IleTyr: 1.173 ± 0.051
0.0IleXaa: 0.0 ± 0.0
Lys
3.618LysAla: 3.618 ± 0.092
0.268LysCys: 0.268 ± 0.026
2.408LysAsp: 2.408 ± 0.063
2.722LysGlu: 2.722 ± 0.076
0.898LysPhe: 0.898 ± 0.044
4.482LysGly: 4.482 ± 0.095
0.476LysHis: 0.476 ± 0.028
1.607LysIle: 1.607 ± 0.064
1.353LysLys: 1.353 ± 0.066
3.27LysLeu: 3.27 ± 0.079
0.983LysMet: 0.983 ± 0.042
0.78LysAsn: 0.78 ± 0.043
1.51LysPro: 1.51 ± 0.054
0.614LysGln: 0.614 ± 0.038
2.6LysArg: 2.6 ± 0.07
1.676LysSer: 1.676 ± 0.056
1.512LysThr: 1.512 ± 0.054
3.932LysVal: 3.932 ± 0.094
0.386LysTrp: 0.386 ± 0.029
0.693LysTyr: 0.693 ± 0.036
0.0LysXaa: 0.0 ± 0.0
Leu
10.42LeuAla: 10.42 ± 0.144
1.496LeuCys: 1.496 ± 0.052
6.118LeuAsp: 6.118 ± 0.107
8.508LeuGlu: 8.508 ± 0.177
3.637LeuPhe: 3.637 ± 0.09
11.175LeuGly: 11.175 ± 0.173
1.588LeuHis: 1.588 ± 0.061
4.445LeuIle: 4.445 ± 0.102
5.341LeuLys: 5.341 ± 0.099
10.415LeuLeu: 10.415 ± 0.174
3.457LeuMet: 3.457 ± 0.084
2.433LeuAsn: 2.433 ± 0.062
5.209LeuPro: 5.209 ± 0.106
2.254LeuGln: 2.254 ± 0.059
7.88LeuArg: 7.88 ± 0.134
8.381LeuSer: 8.381 ± 0.14
4.205LeuThr: 4.205 ± 0.096
9.062LeuVal: 9.062 ± 0.16
1.614LeuTrp: 1.614 ± 0.06
2.069LeuTyr: 2.069 ± 0.066
0.0LeuXaa: 0.0 ± 0.0
Met
3.681MetAla: 3.681 ± 0.082
0.268MetCys: 0.268 ± 0.023
2.189MetAsp: 2.189 ± 0.061
2.856MetGlu: 2.856 ± 0.077
0.721MetPhe: 0.721 ± 0.038
4.179MetGly: 4.179 ± 0.096
0.291MetHis: 0.291 ± 0.022
1.452MetIle: 1.452 ± 0.057
1.065MetLys: 1.065 ± 0.045
2.572MetLeu: 2.572 ± 0.065
0.841MetMet: 0.841 ± 0.038
0.746MetAsn: 0.746 ± 0.039
1.335MetPro: 1.335 ± 0.046
0.399MetGln: 0.399 ± 0.024
2.397MetArg: 2.397 ± 0.065
2.006MetSer: 2.006 ± 0.061
1.365MetThr: 1.365 ± 0.048
2.711MetVal: 2.711 ± 0.078
0.312MetTrp: 0.312 ± 0.024
0.483MetTyr: 0.483 ± 0.027
0.0MetXaa: 0.0 ± 0.0
Asn
1.764AsnAla: 1.764 ± 0.054
0.266AsnCys: 0.266 ± 0.022
0.961AsnAsp: 0.961 ± 0.039
0.912AsnGlu: 0.912 ± 0.044
0.748AsnPhe: 0.748 ± 0.045
1.944AsnGly: 1.944 ± 0.053
0.452AsnHis: 0.452 ± 0.028
0.981AsnIle: 0.981 ± 0.047
0.658AsnLys: 0.658 ± 0.038
2.93AsnLeu: 2.93 ± 0.068
0.695AsnMet: 0.695 ± 0.036
0.499AsnAsn: 0.499 ± 0.034
1.829AsnPro: 1.829 ± 0.064
0.695AsnGln: 0.695 ± 0.033
1.99AsnArg: 1.99 ± 0.064
1.101AsnSer: 1.101 ± 0.047
0.827AsnThr: 0.827 ± 0.04
2.254AsnVal: 2.254 ± 0.059
0.277AsnTrp: 0.277 ± 0.02
0.587AsnTyr: 0.587 ± 0.034
0.0AsnXaa: 0.0 ± 0.0
Pro
3.196ProAla: 3.196 ± 0.078
0.593ProCys: 0.593 ± 0.034
2.598ProAsp: 2.598 ± 0.069
3.616ProGlu: 3.616 ± 0.079
2.101ProPhe: 2.101 ± 0.066
4.572ProGly: 4.572 ± 0.105
1.083ProHis: 1.083 ± 0.047
2.036ProIle: 2.036 ± 0.074
2.164ProLys: 2.164 ± 0.072
5.412ProLeu: 5.412 ± 0.114
1.633ProMet: 1.633 ± 0.055
1.265ProAsn: 1.265 ± 0.049
2.311ProPro: 2.311 ± 0.072
1.535ProGln: 1.535 ± 0.051
3.177ProArg: 3.177 ± 0.073
3.752ProSer: 3.752 ± 0.086
1.836ProThr: 1.836 ± 0.063
4.761ProVal: 4.761 ± 0.098
0.796ProTrp: 0.796 ± 0.038
1.132ProTyr: 1.132 ± 0.044
0.0ProXaa: 0.0 ± 0.0
Gln
2.463GlnAla: 2.463 ± 0.073
0.282GlnCys: 0.282 ± 0.024
1.574GlnAsp: 1.574 ± 0.06
2.39GlnGlu: 2.39 ± 0.075
0.709GlnPhe: 0.709 ± 0.032
2.949GlnGly: 2.949 ± 0.068
0.363GlnHis: 0.363 ± 0.022
1.406GlnIle: 1.406 ± 0.05
0.73GlnLys: 0.73 ± 0.037
2.563GlnLeu: 2.563 ± 0.077
0.908GlnMet: 0.908 ± 0.042
0.531GlnAsn: 0.531 ± 0.031
0.896GlnPro: 0.896 ± 0.043
0.579GlnGln: 0.579 ± 0.036
2.388GlnArg: 2.388 ± 0.073
1.069GlnSer: 1.069 ± 0.042
0.833GlnThr: 0.833 ± 0.038
3.24GlnVal: 3.24 ± 0.08
0.439GlnTrp: 0.439 ± 0.03
0.538GlnTyr: 0.538 ± 0.028
0.0GlnXaa: 0.0 ± 0.0
Arg
6.211ArgAla: 6.211 ± 0.114
1.249ArgCys: 1.249 ± 0.054
4.511ArgAsp: 4.511 ± 0.095
6.225ArgGlu: 6.225 ± 0.119
2.978ArgPhe: 2.978 ± 0.077
7.109ArgGly: 7.109 ± 0.129
1.462ArgHis: 1.462 ± 0.055
4.44ArgIle: 4.44 ± 0.081
2.346ArgLys: 2.346 ± 0.078
8.277ArgLeu: 8.277 ± 0.147
2.672ArgMet: 2.672 ± 0.076
1.685ArgAsn: 1.685 ± 0.052
3.308ArgPro: 3.308 ± 0.089
1.803ArgGln: 1.803 ± 0.063
7.051ArgArg: 7.051 ± 0.147
5.068ArgSer: 5.068 ± 0.108
2.777ArgThr: 2.777 ± 0.073
6.911ArgVal: 6.911 ± 0.125
1.281ArgTrp: 1.281 ± 0.051
2.108ArgTyr: 2.108 ± 0.053
0.0ArgXaa: 0.0 ± 0.0
Ser
5.246SerAla: 5.246 ± 0.097
0.921SerCys: 0.921 ± 0.038
2.761SerAsp: 2.761 ± 0.071
2.829SerGlu: 2.829 ± 0.086
2.674SerPhe: 2.674 ± 0.071
5.897SerGly: 5.897 ± 0.109
1.295SerHis: 1.295 ± 0.048
2.875SerIle: 2.875 ± 0.069
2.194SerLys: 2.194 ± 0.066
7.162SerLeu: 7.162 ± 0.134
1.958SerMet: 1.958 ± 0.054
1.36SerAsn: 1.36 ± 0.054
3.96SerPro: 3.96 ± 0.086
1.999SerGln: 1.999 ± 0.072
4.856SerArg: 4.856 ± 0.097
4.694SerSer: 4.694 ± 0.125
2.418SerThr: 2.418 ± 0.067
5.236SerVal: 5.236 ± 0.103
0.847SerTrp: 0.847 ± 0.04
1.524SerTyr: 1.524 ± 0.053
0.0SerXaa: 0.0 ± 0.0
Thr
3.244ThrAla: 3.244 ± 0.076
0.522ThrCys: 0.522 ± 0.033
1.882ThrAsp: 1.882 ± 0.056
1.799ThrGlu: 1.799 ± 0.051
1.552ThrPhe: 1.552 ± 0.047
4.018ThrGly: 4.018 ± 0.091
0.737ThrHis: 0.737 ± 0.041
1.798ThrIle: 1.798 ± 0.057
1.187ThrLys: 1.187 ± 0.048
4.493ThrLeu: 4.493 ± 0.099
1.071ThrMet: 1.071 ± 0.043
0.91ThrAsn: 0.91 ± 0.042
2.323ThrPro: 2.323 ± 0.063
1.058ThrGln: 1.058 ± 0.046
2.493ThrArg: 2.493 ± 0.072
2.461ThrSer: 2.461 ± 0.065
1.632ThrThr: 1.632 ± 0.062
3.897ThrVal: 3.897 ± 0.1
0.473ThrTrp: 0.473 ± 0.028
1.148ThrTyr: 1.148 ± 0.051
0.0ThrXaa: 0.0 ± 0.0
Val
7.829ValAla: 7.829 ± 0.126
1.083ValCys: 1.083 ± 0.054
5.133ValAsp: 5.133 ± 0.113
6.409ValGlu: 6.409 ± 0.134
2.865ValPhe: 2.865 ± 0.076
7.199ValGly: 7.199 ± 0.136
1.438ValHis: 1.438 ± 0.049
4.475ValIle: 4.475 ± 0.095
3.341ValLys: 3.341 ± 0.074
9.273ValLeu: 9.273 ± 0.129
2.704ValMet: 2.704 ± 0.079
2.228ValAsn: 2.228 ± 0.068
4.699ValPro: 4.699 ± 0.112
2.201ValGln: 2.201 ± 0.06
7.061ValArg: 7.061 ± 0.121
5.832ValSer: 5.832 ± 0.105
4.223ValThr: 4.223 ± 0.101
7.825ValVal: 7.825 ± 0.14
0.81ValTrp: 0.81 ± 0.045
1.801ValTyr: 1.801 ± 0.053
0.0ValXaa: 0.0 ± 0.0
Trp
1.198TrpAla: 1.198 ± 0.05
0.171TrpCys: 0.171 ± 0.015
0.861TrpAsp: 0.861 ± 0.042
0.863TrpGlu: 0.863 ± 0.042
0.43TrpPhe: 0.43 ± 0.033
1.39TrpGly: 1.39 ± 0.055
0.201TrpHis: 0.201 ± 0.02
0.681TrpIle: 0.681 ± 0.038
0.342TrpLys: 0.342 ± 0.024
1.261TrpLeu: 1.261 ± 0.049
0.365TrpMet: 0.365 ± 0.03
0.291TrpAsn: 0.291 ± 0.026
0.483TrpPro: 0.483 ± 0.028
0.28TrpGln: 0.28 ± 0.021
0.981TrpArg: 0.981 ± 0.046
0.716TrpSer: 0.716 ± 0.04
0.506TrpThr: 0.506 ± 0.032
1.168TrpVal: 1.168 ± 0.053
0.203TrpTrp: 0.203 ± 0.018
0.261TrpTyr: 0.261 ± 0.022
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.656TyrAla: 1.656 ± 0.06
0.284TyrCys: 0.284 ± 0.019
1.332TyrAsp: 1.332 ± 0.056
1.2TyrGlu: 1.2 ± 0.049
0.882TyrPhe: 0.882 ± 0.043
2.438TyrGly: 2.438 ± 0.076
0.517TyrHis: 0.517 ± 0.031
0.762TyrIle: 0.762 ± 0.037
0.723TyrLys: 0.723 ± 0.042
2.493TyrLeu: 2.493 ± 0.075
0.526TyrMet: 0.526 ± 0.037
0.566TyrAsn: 0.566 ± 0.036
1.261TyrPro: 1.261 ± 0.047
0.797TyrGln: 0.797 ± 0.041
2.194TyrArg: 2.194 ± 0.059
1.291TyrSer: 1.291 ± 0.053
0.912TyrThr: 0.912 ± 0.039
1.875TyrVal: 1.875 ± 0.059
0.305TyrTrp: 0.305 ± 0.024
0.582TyrTyr: 0.582 ± 0.037
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1737 proteins (566890 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski