Human papillomavirus type 190

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; unclassified Gammapapillomavirus

Average proteome isoelectric point is 5.95

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2S0BEA1|A0A2S0BEA1_9PAPI Protein E6 OS=Human papillomavirus type 190 OX=1851215 GN=E6 PE=3 SV=1
MM1 pKa = 7.62EE2 pKa = 5.41PRR4 pKa = 11.84AKK6 pKa = 9.9RR7 pKa = 11.84QKK9 pKa = 10.17RR10 pKa = 11.84DD11 pKa = 3.45SVEE14 pKa = 3.53NLYY17 pKa = 10.18RR18 pKa = 11.84QCKK21 pKa = 8.4LTGQCPDD28 pKa = 3.27DD29 pKa = 4.54VINKK33 pKa = 9.42VEE35 pKa = 4.15GNTLADD41 pKa = 3.6RR42 pKa = 11.84LLRR45 pKa = 11.84ILGSVIYY52 pKa = 10.6LGGLGIGTGRR62 pKa = 11.84GSGGSTGYY70 pKa = 10.46RR71 pKa = 11.84PIGATTPRR79 pKa = 11.84VTDD82 pKa = 3.47STPIRR87 pKa = 11.84PTVPVDD93 pKa = 3.23PLVPTEE99 pKa = 4.22VLPVDD104 pKa = 3.51PAGPSIVPLTEE115 pKa = 3.78SGIPEE120 pKa = 3.91DD121 pKa = 4.43TIIEE125 pKa = 4.33TSGTAVTVNPTDD137 pKa = 3.62PPVITNIDD145 pKa = 4.31PISDD149 pKa = 3.57VTGVEE154 pKa = 4.11GQPTIITAEE163 pKa = 4.32DD164 pKa = 3.67DD165 pKa = 3.87SVAVLDD171 pKa = 4.36VQPSTPAPKK180 pKa = 10.09RR181 pKa = 11.84VTTGVRR187 pKa = 11.84PRR189 pKa = 11.84TSSPRR194 pKa = 11.84EE195 pKa = 3.65PTLYY199 pKa = 9.95PVPEE203 pKa = 4.15SAAPDD208 pKa = 3.31FTIFVDD214 pKa = 4.41AQALGEE220 pKa = 4.47TIGGEE225 pKa = 4.2YY226 pKa = 9.98IPLEE230 pKa = 4.4EE231 pKa = 4.47FSQLQRR237 pKa = 11.84FEE239 pKa = 5.06IEE241 pKa = 3.92EE242 pKa = 4.0QQPLTSTPEE251 pKa = 3.65QRR253 pKa = 11.84LNRR256 pKa = 11.84AFQRR260 pKa = 11.84ARR262 pKa = 11.84DD263 pKa = 3.75LYY265 pKa = 10.82NRR267 pKa = 11.84QITQIRR273 pKa = 11.84TRR275 pKa = 11.84NLDD278 pKa = 3.42FLGAASRR285 pKa = 11.84AVQFEE290 pKa = 4.2FEE292 pKa = 4.19NPAFIGDD299 pKa = 3.39VSLQFEE305 pKa = 3.98QDD307 pKa = 3.38VRR309 pKa = 11.84NVAAAPDD316 pKa = 3.99PDD318 pKa = 3.56FRR320 pKa = 11.84DD321 pKa = 3.1IVVLHH326 pKa = 6.68RR327 pKa = 11.84ARR329 pKa = 11.84YY330 pKa = 7.04STTDD334 pKa = 2.98TGRR337 pKa = 11.84VRR339 pKa = 11.84VSRR342 pKa = 11.84LGQRR346 pKa = 11.84GTIVTRR352 pKa = 11.84SGAQIGEE359 pKa = 4.41HH360 pKa = 3.98VHH362 pKa = 6.72FYY364 pKa = 11.26YY365 pKa = 10.71DD366 pKa = 3.16ASTIGSDD373 pKa = 3.06AADD376 pKa = 4.61AIEE379 pKa = 5.16LSTLGQHH386 pKa = 6.45SGDD389 pKa = 3.65NAIVDD394 pKa = 4.26ALAEE398 pKa = 4.21SSFINPIEE406 pKa = 4.54NPDD409 pKa = 3.5TTYY412 pKa = 11.17TEE414 pKa = 4.76ADD416 pKa = 3.53LLDD419 pKa = 3.94TQVEE423 pKa = 4.43NFDD426 pKa = 3.96GLHH429 pKa = 6.13LVLSSSGRR437 pKa = 11.84RR438 pKa = 11.84GDD440 pKa = 3.71VYY442 pKa = 10.94SIPTLPPGTTLRR454 pKa = 11.84VFVDD458 pKa = 3.69DD459 pKa = 3.76YY460 pKa = 11.89GRR462 pKa = 11.84DD463 pKa = 3.49LFVSYY468 pKa = 9.96PVSHH472 pKa = 7.04TKK474 pKa = 9.99TDD476 pKa = 3.35VLIPDD481 pKa = 4.72EE482 pKa = 4.34YY483 pKa = 11.14LHH485 pKa = 6.54PLEE488 pKa = 5.11PPILLDD494 pKa = 3.8VYY496 pKa = 11.28SSDD499 pKa = 4.44YY500 pKa = 10.69YY501 pKa = 10.93LHH503 pKa = 6.96PSLWSRR509 pKa = 11.84RR510 pKa = 11.84KK511 pKa = 9.64RR512 pKa = 11.84KK513 pKa = 10.01RR514 pKa = 11.84SDD516 pKa = 2.5IYY518 pKa = 11.62NFFTDD523 pKa = 3.75GTVDD527 pKa = 3.15ATEE530 pKa = 3.84WW531 pKa = 3.26

Molecular weight: 58.29 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2S0BE77|A0A2S0BE77_9PAPI Minor capsid protein L2 OS=Human papillomavirus type 190 OX=1851215 GN=L2 PE=3 SV=1
MM1 pKa = 7.49EE2 pKa = 4.93WLTQRR7 pKa = 11.84FNAVQEE13 pKa = 4.06ALLNLIEE20 pKa = 5.12QGAEE24 pKa = 3.92DD25 pKa = 4.97LDD27 pKa = 4.15SQIEE31 pKa = 4.09YY32 pKa = 9.14WNNVRR37 pKa = 11.84KK38 pKa = 10.07EE39 pKa = 4.14NVYY42 pKa = 9.03MYY44 pKa = 9.06YY45 pKa = 10.86AKK47 pKa = 10.48RR48 pKa = 11.84EE49 pKa = 4.13GLTHH53 pKa = 7.23IGLQPLPVPAVSEE66 pKa = 4.36YY67 pKa = 10.27KK68 pKa = 10.53AKK70 pKa = 10.38QAIHH74 pKa = 6.71LVLLLQSLKK83 pKa = 10.42KK84 pKa = 10.01SAYY87 pKa = 9.9AKK89 pKa = 10.36EE90 pKa = 4.09SWTLQNTSEE99 pKa = 4.27EE100 pKa = 4.74LINTQPKK107 pKa = 10.61DD108 pKa = 3.61CFKK111 pKa = 10.38KK112 pKa = 9.74HH113 pKa = 6.45PYY115 pKa = 8.21TVEE118 pKa = 3.36VWFDD122 pKa = 3.08NDD124 pKa = 3.52KK125 pKa = 11.27NNSYY129 pKa = 10.74PYY131 pKa = 10.07INWDD135 pKa = 3.5AIYY138 pKa = 10.67YY139 pKa = 9.85QDD141 pKa = 5.31SQEE144 pKa = 4.16KK145 pKa = 6.18WHH147 pKa = 6.44KK148 pKa = 10.75VPGLVDD154 pKa = 3.71YY155 pKa = 11.46NGLYY159 pKa = 9.67YY160 pKa = 10.94NEE162 pKa = 4.3VGGDD166 pKa = 2.9RR167 pKa = 11.84VYY169 pKa = 11.11FQIFDD174 pKa = 4.02ADD176 pKa = 3.56AQKK179 pKa = 10.93YY180 pKa = 7.94GHH182 pKa = 6.19TGMWTVHH189 pKa = 6.43FKK191 pKa = 11.11RR192 pKa = 11.84EE193 pKa = 4.02TLVAPISSSKK203 pKa = 10.39QSSSYY208 pKa = 10.41SGKK211 pKa = 10.51APTSVPSSSKK221 pKa = 9.0NTLPSKK227 pKa = 9.75EE228 pKa = 4.23SPRR231 pKa = 11.84RR232 pKa = 11.84LQRR235 pKa = 11.84PEE237 pKa = 4.02VGSSTGEE244 pKa = 3.48AAAVRR249 pKa = 11.84RR250 pKa = 11.84RR251 pKa = 11.84RR252 pKa = 11.84RR253 pKa = 11.84EE254 pKa = 3.73QGEE257 pKa = 4.26SSTDD261 pKa = 3.56GEE263 pKa = 4.42PTTTSKK269 pKa = 10.52RR270 pKa = 11.84RR271 pKa = 11.84RR272 pKa = 11.84GGGGGGAGRR281 pKa = 11.84LGVSPEE287 pKa = 4.15EE288 pKa = 4.23VGSRR292 pKa = 11.84HH293 pKa = 5.88HH294 pKa = 6.69SATGHH299 pKa = 5.24HH300 pKa = 6.94RR301 pKa = 11.84SRR303 pKa = 11.84LEE305 pKa = 3.6QLKK308 pKa = 10.59EE309 pKa = 3.81EE310 pKa = 4.51ARR312 pKa = 11.84DD313 pKa = 3.69PPILIVTGPANSLKK327 pKa = 9.67CWRR330 pKa = 11.84YY331 pKa = 9.6RR332 pKa = 11.84KK333 pKa = 9.56QNSNTFPFLAISTIFTWVGGCGTAEE358 pKa = 3.97QSRR361 pKa = 11.84MLIAFRR367 pKa = 11.84NNDD370 pKa = 3.01EE371 pKa = 3.85RR372 pKa = 11.84TQFLKK377 pKa = 10.84YY378 pKa = 10.12VHH380 pKa = 6.67FPKK383 pKa = 9.5QTTYY387 pKa = 11.95ALGQLDD393 pKa = 3.79KK394 pKa = 11.53LL395 pKa = 4.16

Molecular weight: 44.92 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

2286

95

607

381.0

43.11

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.08 ± 0.394

2.231 ± 0.753

6.737 ± 0.945

5.949 ± 0.577

4.243 ± 0.384

5.731 ± 0.836

2.012 ± 0.26

5.074 ± 0.46

5.162 ± 1.082

9.011 ± 0.575

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.487 ± 0.542

4.549 ± 0.526

5.643 ± 1.107

5.293 ± 0.397

5.731 ± 0.833

7.174 ± 0.658

6.212 ± 0.846

6.299 ± 0.543

1.312 ± 0.299

4.068 ± 0.317
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski