Amino acid dipepetide frequency for Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.618AlaAla: 12.618 ± 0.134
0.936AlaCys: 0.936 ± 0.029
5.396AlaAsp: 5.396 ± 0.078
7.101AlaGlu: 7.101 ± 0.099
4.204AlaPhe: 4.204 ± 0.066
8.158AlaGly: 8.158 ± 0.106
1.935AlaHis: 1.935 ± 0.04
5.87AlaIle: 5.87 ± 0.069
5.234AlaLys: 5.234 ± 0.082
10.478AlaLeu: 10.478 ± 0.111
2.51AlaMet: 2.51 ± 0.042
3.584AlaAsn: 3.584 ± 0.059
3.804AlaPro: 3.804 ± 0.067
3.728AlaGln: 3.728 ± 0.055
5.905AlaArg: 5.905 ± 0.079
5.56AlaSer: 5.56 ± 0.077
5.586AlaThr: 5.586 ± 0.105
6.593AlaVal: 6.593 ± 0.077
1.035AlaTrp: 1.035 ± 0.029
2.717AlaTyr: 2.717 ± 0.046
0.0AlaXaa: 0.0 ± 0.0
Cys
0.885CysAla: 0.885 ± 0.028
0.096CysCys: 0.096 ± 0.009
0.415CysAsp: 0.415 ± 0.018
0.445CysGlu: 0.445 ± 0.018
0.329CysPhe: 0.329 ± 0.017
0.831CysGly: 0.831 ± 0.022
0.251CysHis: 0.251 ± 0.016
0.432CysIle: 0.432 ± 0.017
0.357CysLys: 0.357 ± 0.015
0.772CysLeu: 0.772 ± 0.027
0.171CysMet: 0.171 ± 0.011
0.333CysAsn: 0.333 ± 0.016
0.388CysPro: 0.388 ± 0.017
0.224CysGln: 0.224 ± 0.012
0.551CysArg: 0.551 ± 0.02
0.62CysSer: 0.62 ± 0.026
0.528CysThr: 0.528 ± 0.023
0.551CysVal: 0.551 ± 0.022
0.078CysTrp: 0.078 ± 0.007
0.272CysTyr: 0.272 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
5.075AspAla: 5.075 ± 0.067
0.43AspCys: 0.43 ± 0.018
2.192AspAsp: 2.192 ± 0.051
3.1AspGlu: 3.1 ± 0.061
2.869AspPhe: 2.869 ± 0.052
3.417AspGly: 3.417 ± 0.06
0.946AspHis: 0.946 ± 0.025
3.092AspIle: 3.092 ± 0.054
2.635AspLys: 2.635 ± 0.054
4.969AspLeu: 4.969 ± 0.06
1.108AspMet: 1.108 ± 0.031
1.618AspAsn: 1.618 ± 0.035
1.859AspPro: 1.859 ± 0.04
1.39AspGln: 1.39 ± 0.031
2.779AspArg: 2.779 ± 0.048
2.768AspSer: 2.768 ± 0.05
2.617AspThr: 2.617 ± 0.057
2.892AspVal: 2.892 ± 0.048
0.656AspTrp: 0.656 ± 0.024
1.935AspTyr: 1.935 ± 0.04
0.0AspXaa: 0.0 ± 0.0
Glu
5.579GluAla: 5.579 ± 0.079
0.382GluCys: 0.382 ± 0.017
2.267GluAsp: 2.267 ± 0.046
3.176GluGlu: 3.176 ± 0.06
2.701GluPhe: 2.701 ± 0.039
3.315GluGly: 3.315 ± 0.06
1.27GluHis: 1.27 ± 0.034
4.523GluIle: 4.523 ± 0.07
4.913GluLys: 4.913 ± 0.077
5.856GluLeu: 5.856 ± 0.078
1.428GluMet: 1.428 ± 0.035
2.801GluAsn: 2.801 ± 0.05
2.103GluPro: 2.103 ± 0.039
2.071GluGln: 2.071 ± 0.041
3.802GluArg: 3.802 ± 0.059
3.454GluSer: 3.454 ± 0.05
3.381GluThr: 3.381 ± 0.046
3.486GluVal: 3.486 ± 0.068
0.635GluTrp: 0.635 ± 0.026
1.915GluTyr: 1.915 ± 0.037
0.0GluXaa: 0.0 ± 0.0
Phe
4.942PheAla: 4.942 ± 0.063
0.463PheCys: 0.463 ± 0.019
2.59PheAsp: 2.59 ± 0.045
2.706PheGlu: 2.706 ± 0.052
2.545PhePhe: 2.545 ± 0.05
3.421PheGly: 3.421 ± 0.062
0.885PheHis: 0.885 ± 0.026
2.602PheIle: 2.602 ± 0.052
2.038PheLys: 2.038 ± 0.045
4.354PheLeu: 4.354 ± 0.067
1.142PheMet: 1.142 ± 0.034
1.752PheAsn: 1.752 ± 0.038
1.684PhePro: 1.684 ± 0.038
1.411PheGln: 1.411 ± 0.035
2.498PheArg: 2.498 ± 0.053
3.627PheSer: 3.627 ± 0.054
2.932PheThr: 2.932 ± 0.054
3.192PheVal: 3.192 ± 0.054
0.636PheTrp: 0.636 ± 0.026
1.704PheTyr: 1.704 ± 0.037
0.0PheXaa: 0.0 ± 0.0
Gly
6.809GlyAla: 6.809 ± 0.087
0.711GlyCys: 0.711 ± 0.026
3.669GlyAsp: 3.669 ± 0.052
4.264GlyGlu: 4.264 ± 0.061
3.674GlyPhe: 3.674 ± 0.057
5.558GlyGly: 5.558 ± 0.108
1.453GlyHis: 1.453 ± 0.033
4.577GlyIle: 4.577 ± 0.058
4.705GlyLys: 4.705 ± 0.069
6.47GlyLeu: 6.47 ± 0.081
1.698GlyMet: 1.698 ± 0.035
2.953GlyAsn: 2.953 ± 0.07
1.977GlyPro: 1.977 ± 0.037
2.398GlyGln: 2.398 ± 0.05
3.749GlyArg: 3.749 ± 0.062
4.704GlySer: 4.704 ± 0.088
4.169GlyThr: 4.169 ± 0.107
4.996GlyVal: 4.996 ± 0.063
0.816GlyTrp: 0.816 ± 0.025
2.73GlyTyr: 2.73 ± 0.047
0.0GlyXaa: 0.0 ± 0.0
His
2.017HisAla: 2.017 ± 0.052
0.224HisCys: 0.224 ± 0.013
1.071HisAsp: 1.071 ± 0.031
1.317HisGlu: 1.317 ± 0.035
1.149HisPhe: 1.149 ± 0.031
1.524HisGly: 1.524 ± 0.036
0.596HisHis: 0.596 ± 0.024
1.156HisIle: 1.156 ± 0.031
0.901HisLys: 0.901 ± 0.026
2.095HisLeu: 2.095 ± 0.044
0.429HisMet: 0.429 ± 0.017
0.735HisAsn: 0.735 ± 0.022
0.984HisPro: 0.984 ± 0.029
0.583HisGln: 0.583 ± 0.022
1.303HisArg: 1.303 ± 0.033
1.235HisSer: 1.235 ± 0.029
1.048HisThr: 1.048 ± 0.027
1.274HisVal: 1.274 ± 0.033
0.269HisTrp: 0.269 ± 0.014
0.828HisTyr: 0.828 ± 0.023
0.0HisXaa: 0.0 ± 0.0
Ile
6.614IleAla: 6.614 ± 0.08
0.584IleCys: 0.584 ± 0.02
3.487IleAsp: 3.487 ± 0.055
3.964IleGlu: 3.964 ± 0.059
2.923IlePhe: 2.923 ± 0.058
4.319IleGly: 4.319 ± 0.073
1.169IleHis: 1.169 ± 0.027
3.231IleIle: 3.231 ± 0.059
2.621IleLys: 2.621 ± 0.047
5.68IleLeu: 5.68 ± 0.07
1.155IleMet: 1.155 ± 0.035
2.136IleAsn: 2.136 ± 0.041
2.433IlePro: 2.433 ± 0.048
1.877IleGln: 1.877 ± 0.038
3.387IleArg: 3.387 ± 0.049
4.149IleSer: 4.149 ± 0.057
3.517IleThr: 3.517 ± 0.058
4.005IleVal: 4.005 ± 0.061
0.653IleTrp: 0.653 ± 0.021
2.087IleTyr: 2.087 ± 0.042
0.0IleXaa: 0.0 ± 0.0
Lys
5.078LysAla: 5.078 ± 0.083
0.307LysCys: 0.307 ± 0.017
2.687LysAsp: 2.687 ± 0.05
3.127LysGlu: 3.127 ± 0.064
2.237LysPhe: 2.237 ± 0.047
3.314LysGly: 3.314 ± 0.054
1.016LysHis: 1.016 ± 0.026
3.872LysIle: 3.872 ± 0.063
4.352LysLys: 4.352 ± 0.09
5.228LysLeu: 5.228 ± 0.072
1.432LysMet: 1.432 ± 0.035
2.584LysAsn: 2.584 ± 0.045
2.776LysPro: 2.776 ± 0.052
1.831LysGln: 1.831 ± 0.047
2.946LysArg: 2.946 ± 0.051
3.417LysSer: 3.417 ± 0.054
3.387LysThr: 3.387 ± 0.057
3.373LysVal: 3.373 ± 0.053
0.537LysTrp: 0.537 ± 0.02
1.798LysTyr: 1.798 ± 0.04
0.0LysXaa: 0.0 ± 0.0
Leu
10.535LeuAla: 10.535 ± 0.107
0.842LeuCys: 0.842 ± 0.026
4.402LeuAsp: 4.402 ± 0.055
5.3LeuGlu: 5.3 ± 0.071
4.48LeuPhe: 4.48 ± 0.077
6.599LeuGly: 6.599 ± 0.079
2.029LeuHis: 2.029 ± 0.049
5.705LeuIle: 5.705 ± 0.081
6.22LeuLys: 6.22 ± 0.087
9.668LeuLeu: 9.668 ± 0.122
2.285LeuMet: 2.285 ± 0.042
3.844LeuAsn: 3.844 ± 0.056
4.937LeuPro: 4.937 ± 0.075
3.748LeuGln: 3.748 ± 0.058
6.255LeuArg: 6.255 ± 0.083
6.635LeuSer: 6.635 ± 0.071
5.719LeuThr: 5.719 ± 0.077
6.544LeuVal: 6.544 ± 0.086
1.129LeuTrp: 1.129 ± 0.032
2.993LeuTyr: 2.993 ± 0.056
0.0LeuXaa: 0.0 ± 0.0
Met
2.416MetAla: 2.416 ± 0.038
0.139MetCys: 0.139 ± 0.011
0.728MetAsp: 0.728 ± 0.024
0.839MetGlu: 0.839 ± 0.025
0.775MetPhe: 0.775 ± 0.024
1.482MetGly: 1.482 ± 0.029
0.569MetHis: 0.569 ± 0.021
1.2MetIle: 1.2 ± 0.035
1.554MetLys: 1.554 ± 0.033
2.463MetLeu: 2.463 ± 0.046
0.492MetMet: 0.492 ± 0.02
0.985MetAsn: 0.985 ± 0.024
1.336MetPro: 1.336 ± 0.032
1.201MetGln: 1.201 ± 0.035
1.817MetArg: 1.817 ± 0.034
1.397MetSer: 1.397 ± 0.032
1.327MetThr: 1.327 ± 0.033
1.405MetVal: 1.405 ± 0.034
0.17MetTrp: 0.17 ± 0.012
0.479MetTyr: 0.479 ± 0.02
0.0MetXaa: 0.0 ± 0.0
Asn
3.796AsnAla: 3.796 ± 0.065
0.373AsnCys: 0.373 ± 0.021
1.728AsnAsp: 1.728 ± 0.041
2.109AsnGlu: 2.109 ± 0.04
2.006AsnPhe: 2.006 ± 0.04
2.793AsnGly: 2.793 ± 0.074
0.78AsnHis: 0.78 ± 0.028
2.378AsnIle: 2.378 ± 0.046
1.702AsnLys: 1.702 ± 0.036
4.276AsnLeu: 4.276 ± 0.063
0.809AsnMet: 0.809 ± 0.023
1.428AsnAsn: 1.428 ± 0.047
2.212AsnPro: 2.212 ± 0.047
1.306AsnGln: 1.306 ± 0.037
2.303AsnArg: 2.303 ± 0.042
2.282AsnSer: 2.282 ± 0.056
2.154AsnThr: 2.154 ± 0.058
2.311AsnVal: 2.311 ± 0.052
0.494AsnTrp: 0.494 ± 0.023
1.346AsnTyr: 1.346 ± 0.04
0.0AsnXaa: 0.0 ± 0.0
Pro
4.735ProAla: 4.735 ± 0.069
0.249ProCys: 0.249 ± 0.013
2.276ProAsp: 2.276 ± 0.042
3.234ProGlu: 3.234 ± 0.052
1.823ProPhe: 1.823 ± 0.037
3.27ProGly: 3.27 ± 0.046
0.909ProHis: 0.909 ± 0.027
1.977ProIle: 1.977 ± 0.035
1.983ProLys: 1.983 ± 0.044
4.005ProLeu: 4.005 ± 0.068
0.986ProMet: 0.986 ± 0.027
1.446ProAsn: 1.446 ± 0.033
1.609ProPro: 1.609 ± 0.042
1.826ProGln: 1.826 ± 0.038
2.029ProArg: 2.029 ± 0.04
1.936ProSer: 1.936 ± 0.037
2.062ProThr: 2.062 ± 0.049
3.397ProVal: 3.397 ± 0.053
0.534ProTrp: 0.534 ± 0.02
1.269ProTyr: 1.269 ± 0.032
0.0ProXaa: 0.0 ± 0.0
Gln
3.256GlnAla: 3.256 ± 0.052
0.247GlnCys: 0.247 ± 0.014
1.346GlnAsp: 1.346 ± 0.031
1.527GlnGlu: 1.527 ± 0.036
1.56GlnPhe: 1.56 ± 0.035
2.37GlnGly: 2.37 ± 0.04
0.75GlnHis: 0.75 ± 0.024
2.525GlnIle: 2.525 ± 0.04
2.649GlnLys: 2.649 ± 0.046
3.578GlnLeu: 3.578 ± 0.052
0.9GlnMet: 0.9 ± 0.027
1.846GlnAsn: 1.846 ± 0.039
1.414GlnPro: 1.414 ± 0.035
1.53GlnGln: 1.53 ± 0.036
2.101GlnArg: 2.101 ± 0.045
2.036GlnSer: 2.036 ± 0.046
2.077GlnThr: 2.077 ± 0.043
2.516GlnVal: 2.516 ± 0.04
0.371GlnTrp: 0.371 ± 0.018
1.098GlnTyr: 1.098 ± 0.031
0.0GlnXaa: 0.0 ± 0.0
Arg
5.225ArgAla: 5.225 ± 0.078
0.419ArgCys: 0.419 ± 0.019
3.034ArgAsp: 3.034 ± 0.044
3.982ArgGlu: 3.982 ± 0.065
2.969ArgPhe: 2.969 ± 0.056
3.459ArgGly: 3.459 ± 0.056
1.435ArgHis: 1.435 ± 0.037
3.996ArgIle: 3.996 ± 0.055
3.265ArgLys: 3.265 ± 0.053
6.319ArgLeu: 6.319 ± 0.082
1.419ArgMet: 1.419 ± 0.03
2.131ArgAsn: 2.131 ± 0.044
2.052ArgPro: 2.052 ± 0.042
2.267ArgGln: 2.267 ± 0.045
3.932ArgArg: 3.932 ± 0.069
3.487ArgSer: 3.487 ± 0.061
2.68ArgThr: 2.68 ± 0.042
3.877ArgVal: 3.877 ± 0.055
0.705ArgTrp: 0.705 ± 0.025
2.181ArgTyr: 2.181 ± 0.042
0.0ArgXaa: 0.0 ± 0.0
Ser
6.702SerAla: 6.702 ± 0.094
0.568SerCys: 0.568 ± 0.022
3.153SerAsp: 3.153 ± 0.048
3.761SerGlu: 3.761 ± 0.051
2.76SerPhe: 2.76 ± 0.044
5.722SerGly: 5.722 ± 0.09
1.204SerHis: 1.204 ± 0.032
3.372SerIle: 3.372 ± 0.05
2.522SerLys: 2.522 ± 0.05
6.418SerLeu: 6.418 ± 0.08
1.32SerMet: 1.32 ± 0.031
2.016SerAsn: 2.016 ± 0.05
2.767SerPro: 2.767 ± 0.043
2.07SerGln: 2.07 ± 0.042
3.488SerArg: 3.488 ± 0.059
3.591SerSer: 3.591 ± 0.081
3.311SerThr: 3.311 ± 0.076
4.243SerVal: 4.243 ± 0.065
0.705SerTrp: 0.705 ± 0.024
1.894SerTyr: 1.894 ± 0.042
0.0SerXaa: 0.0 ± 0.0
Thr
5.987ThrAla: 5.987 ± 0.102
0.54ThrCys: 0.54 ± 0.025
2.723ThrAsp: 2.723 ± 0.05
3.079ThrGlu: 3.079 ± 0.05
2.405ThrPhe: 2.405 ± 0.052
5.285ThrGly: 5.285 ± 0.093
1.091ThrHis: 1.091 ± 0.03
3.344ThrIle: 3.344 ± 0.054
2.215ThrLys: 2.215 ± 0.052
5.765ThrLeu: 5.765 ± 0.072
1.112ThrMet: 1.112 ± 0.03
2.096ThrAsn: 2.096 ± 0.067
2.742ThrPro: 2.742 ± 0.049
1.969ThrGln: 1.969 ± 0.04
2.969ThrArg: 2.969 ± 0.054
3.266ThrSer: 3.266 ± 0.088
3.468ThrThr: 3.468 ± 0.101
3.981ThrVal: 3.981 ± 0.081
0.665ThrTrp: 0.665 ± 0.024
1.825ThrTyr: 1.825 ± 0.05
0.0ThrXaa: 0.0 ± 0.0
Val
6.704ValAla: 6.704 ± 0.077
0.571ValCys: 0.571 ± 0.02
3.047ValAsp: 3.047 ± 0.055
3.747ValGlu: 3.747 ± 0.054
3.213ValPhe: 3.213 ± 0.055
4.169ValGly: 4.169 ± 0.062
1.338ValHis: 1.338 ± 0.033
3.965ValIle: 3.965 ± 0.06
3.5ValLys: 3.5 ± 0.057
6.442ValLeu: 6.442 ± 0.077
1.554ValMet: 1.554 ± 0.039
2.555ValAsn: 2.555 ± 0.057
2.669ValPro: 2.669 ± 0.05
2.252ValGln: 2.252 ± 0.045
3.863ValArg: 3.863 ± 0.054
4.558ValSer: 4.558 ± 0.07
4.212ValThr: 4.212 ± 0.078
4.64ValVal: 4.64 ± 0.065
0.738ValTrp: 0.738 ± 0.023
2.269ValTyr: 2.269 ± 0.044
0.0ValXaa: 0.0 ± 0.0
Trp
0.863TrpAla: 0.863 ± 0.029
0.105TrpCys: 0.105 ± 0.008
0.44TrpAsp: 0.44 ± 0.019
0.452TrpGlu: 0.452 ± 0.019
0.597TrpPhe: 0.597 ± 0.024
0.821TrpGly: 0.821 ± 0.026
0.388TrpHis: 0.388 ± 0.017
0.515TrpIle: 0.515 ± 0.021
0.498TrpLys: 0.498 ± 0.02
1.383TrpLeu: 1.383 ± 0.039
0.211TrpMet: 0.211 ± 0.013
0.445TrpAsn: 0.445 ± 0.022
0.471TrpPro: 0.471 ± 0.021
0.848TrpGln: 0.848 ± 0.028
0.826TrpArg: 0.826 ± 0.028
0.68TrpSer: 0.68 ± 0.026
0.454TrpThr: 0.454 ± 0.022
0.769TrpVal: 0.769 ± 0.023
0.148TrpTrp: 0.148 ± 0.011
0.458TrpTyr: 0.458 ± 0.018
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.115TyrAla: 3.115 ± 0.052
0.34TyrCys: 0.34 ± 0.015
1.696TyrAsp: 1.696 ± 0.038
1.828TyrGlu: 1.828 ± 0.042
1.904TyrPhe: 1.904 ± 0.04
2.253TyrGly: 2.253 ± 0.047
0.722TyrHis: 0.722 ± 0.021
1.658TyrIle: 1.658 ± 0.035
1.435TyrLys: 1.435 ± 0.035
3.652TyrLeu: 3.652 ± 0.055
0.614TyrMet: 0.614 ± 0.022
1.297TyrAsn: 1.297 ± 0.039
1.34TyrPro: 1.34 ± 0.03
1.165TyrGln: 1.165 ± 0.027
2.331TyrArg: 2.331 ± 0.044
2.187TyrSer: 2.187 ± 0.044
1.9TyrThr: 1.9 ± 0.043
1.959TyrVal: 1.959 ± 0.04
0.399TyrTrp: 0.399 ± 0.018
1.277TyrTyr: 1.277 ± 0.04
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4092 proteins (1328464 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski