Amino acid dipepetide frequency for Mucor lusitanicus CBS 277.49

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.141AlaAla: 7.141 ± 0.055	1.101AlaCys: 1.101 ± 0.019	3.659AlaAsp: 3.659 ± 0.03	3.902AlaGlu: 3.902 ± 0.036	2.982AlaPhe: 2.982 ± 0.029	3.807AlaGly: 3.807 ± 0.042	1.623AlaHis: 1.623 ± 0.02	4.57AlaIle: 4.57 ± 0.037	4.365AlaLys: 4.365 ± 0.035	6.929AlaLeu: 6.929 ± 0.048	1.979AlaMet: 1.979 ± 0.023	3.279AlaAsn: 3.279 ± 0.032	3.15AlaPro: 3.15 ± 0.032	2.869AlaGln: 2.869 ± 0.029	3.179AlaArg: 3.179 ± 0.029	6.332AlaSer: 6.332 ± 0.043	4.936AlaThr: 4.936 ± 0.037	4.618AlaVal: 4.618 ± 0.038	0.793AlaTrp: 0.793 ± 0.014	2.328AlaTyr: 2.328 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	0.888CysAla: 0.888 ± 0.014	0.35CysCys: 0.35 ± 0.01	0.739CysAsp: 0.739 ± 0.015	0.656CysGlu: 0.656 ± 0.013	0.682CysPhe: 0.682 ± 0.013	0.93CysGly: 0.93 ± 0.014	0.427CysHis: 0.427 ± 0.01	0.995CysIle: 0.995 ± 0.015	0.808CysLys: 0.808 ± 0.015	1.498CysLeu: 1.498 ± 0.021	0.354CysMet: 0.354 ± 0.01	0.643CysAsn: 0.643 ± 0.013	0.681CysPro: 0.681 ± 0.015	0.645CysGln: 0.645 ± 0.012	0.762CysArg: 0.762 ± 0.014	1.09CysSer: 1.09 ± 0.016	0.79CysThr: 0.79 ± 0.013	0.937CysVal: 0.937 ± 0.015	0.195CysTrp: 0.195 ± 0.006	0.536CysTyr: 0.536 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	4.261AspAla: 4.261 ± 0.037	0.714AspCys: 0.714 ± 0.014	4.576AspAsp: 4.576 ± 0.044	4.332AspGlu: 4.332 ± 0.037	2.438AspPhe: 2.438 ± 0.02	3.026AspGly: 3.026 ± 0.031	1.428AspHis: 1.428 ± 0.019	3.82AspIle: 3.82 ± 0.032	3.212AspLys: 3.212 ± 0.031	5.261AspLeu: 5.261 ± 0.038	1.637AspMet: 1.637 ± 0.018	2.509AspAsn: 2.509 ± 0.026	2.648AspPro: 2.648 ± 0.03	2.507AspGln: 2.507 ± 0.026	2.508AspArg: 2.508 ± 0.026	3.709AspSer: 3.709 ± 0.031	3.437AspThr: 3.437 ± 0.034	3.632AspVal: 3.632 ± 0.03	0.744AspTrp: 0.744 ± 0.013	2.137AspTyr: 2.137 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	4.508GluAla: 4.508 ± 0.035	0.75GluCys: 0.75 ± 0.014	4.065GluAsp: 4.065 ± 0.033	5.446GluGlu: 5.446 ± 0.054	2.276GluPhe: 2.276 ± 0.023	2.688GluGly: 2.688 ± 0.026	1.531GluHis: 1.531 ± 0.018	3.368GluIle: 3.368 ± 0.031	4.374GluLys: 4.374 ± 0.04	5.369GluLeu: 5.369 ± 0.04	1.514GluMet: 1.514 ± 0.019	2.827GluAsn: 2.827 ± 0.026	2.106GluPro: 2.106 ± 0.021	3.0GluGln: 3.0 ± 0.03	3.095GluArg: 3.095 ± 0.029	3.922GluSer: 3.922 ± 0.031	3.171GluThr: 3.171 ± 0.023	2.873GluVal: 2.873 ± 0.033	0.698GluTrp: 0.698 ± 0.013	2.069GluTyr: 2.069 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	2.88PheAla: 2.88 ± 0.028	0.71PheCys: 0.71 ± 0.013	2.658PheAsp: 2.658 ± 0.024	2.435PheGlu: 2.435 ± 0.024	1.831PhePhe: 1.831 ± 0.027	2.67PheGly: 2.67 ± 0.03	0.954PheHis: 0.954 ± 0.016	2.484PheIle: 2.484 ± 0.026	2.253PheLys: 2.253 ± 0.026	3.685PheLeu: 3.685 ± 0.036	1.096PheMet: 1.096 ± 0.015	1.912PheAsn: 1.912 ± 0.022	1.654PhePro: 1.654 ± 0.022	1.59PheGln: 1.59 ± 0.017	1.755PheArg: 1.755 ± 0.021	3.156PheSer: 3.156 ± 0.031	2.35PheThr: 2.35 ± 0.025	2.829PheVal: 2.829 ± 0.026	0.573PheTrp: 0.573 ± 0.013	1.565PheTyr: 1.565 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	3.556GlyAla: 3.556 ± 0.038	0.831GlyCys: 0.831 ± 0.016	2.81GlyAsp: 2.81 ± 0.028	2.608GlyGlu: 2.608 ± 0.027	2.509GlyPhe: 2.509 ± 0.028	3.797GlyGly: 3.797 ± 0.047	1.453GlyHis: 1.453 ± 0.021	3.345GlyIle: 3.345 ± 0.03	3.215GlyLys: 3.215 ± 0.035	4.796GlyLeu: 4.796 ± 0.032	1.242GlyMet: 1.242 ± 0.02	2.354GlyAsn: 2.354 ± 0.023	1.86GlyPro: 1.86 ± 0.023	2.039GlyGln: 2.039 ± 0.022	2.503GlyArg: 2.503 ± 0.027	4.215GlySer: 4.215 ± 0.036	2.952GlyThr: 2.952 ± 0.03	3.492GlyVal: 3.492 ± 0.033	0.756GlyTrp: 0.756 ± 0.013	2.097GlyTyr: 2.097 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.744HisAla: 1.744 ± 0.022	0.464HisCys: 0.464 ± 0.01	1.431HisAsp: 1.431 ± 0.021	1.282HisGlu: 1.282 ± 0.02	1.118HisPhe: 1.118 ± 0.018	1.389HisGly: 1.389 ± 0.019	1.376HisHis: 1.376 ± 0.026	1.561HisIle: 1.561 ± 0.018	1.297HisLys: 1.297 ± 0.017	2.564HisLeu: 2.564 ± 0.026	0.663HisMet: 0.663 ± 0.012	1.106HisAsn: 1.106 ± 0.015	1.516HisPro: 1.516 ± 0.018	1.514HisGln: 1.514 ± 0.021	1.378HisArg: 1.378 ± 0.018	1.802HisSer: 1.802 ± 0.022	1.466HisThr: 1.466 ± 0.02	1.676HisVal: 1.676 ± 0.019	0.325HisTrp: 0.325 ± 0.007	1.0HisTyr: 1.0 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	4.355IleAla: 4.355 ± 0.036	0.932IleCys: 0.932 ± 0.015	3.612IleAsp: 3.612 ± 0.03	3.473IleGlu: 3.473 ± 0.029	2.324IlePhe: 2.324 ± 0.026	3.097IleGly: 3.097 ± 0.035	1.646IleHis: 1.646 ± 0.022	3.36IleIle: 3.36 ± 0.034	3.672IleLys: 3.672 ± 0.032	5.215IleLeu: 5.215 ± 0.032	1.492IleMet: 1.492 ± 0.019	2.643IleAsn: 2.643 ± 0.023	3.013IlePro: 3.013 ± 0.023	2.697IleGln: 2.697 ± 0.029	2.9IleArg: 2.9 ± 0.029	4.227IleSer: 4.227 ± 0.035	3.511IleThr: 3.511 ± 0.033	3.891IleVal: 3.891 ± 0.026	0.706IleTrp: 0.706 ± 0.014	2.012IleTyr: 2.012 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	4.392LysAla: 4.392 ± 0.034	0.741LysCys: 0.741 ± 0.015	3.527LysAsp: 3.527 ± 0.033	4.224LysGlu: 4.224 ± 0.039	2.052LysPhe: 2.052 ± 0.022	2.682LysGly: 2.682 ± 0.032	1.588LysHis: 1.588 ± 0.019	3.226LysIle: 3.226 ± 0.03	5.201LysLys: 5.201 ± 0.05	5.399LysLeu: 5.399 ± 0.04	1.504LysMet: 1.504 ± 0.017	2.781LysAsn: 2.781 ± 0.027	2.727LysPro: 2.727 ± 0.026	3.051LysGln: 3.051 ± 0.026	3.809LysArg: 3.809 ± 0.031	4.483LysSer: 4.483 ± 0.036	3.477LysThr: 3.477 ± 0.028	3.425LysVal: 3.425 ± 0.035	0.682LysTrp: 0.682 ± 0.013	2.16LysTyr: 2.16 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	6.64LeuAla: 6.64 ± 0.038	1.435LeuCys: 1.435 ± 0.02	5.502LeuAsp: 5.502 ± 0.043	5.536LeuGlu: 5.536 ± 0.038	3.842LeuPhe: 3.842 ± 0.036	4.873LeuGly: 4.873 ± 0.039	2.302LeuHis: 2.302 ± 0.026	5.023LeuIle: 5.023 ± 0.037	5.764LeuLys: 5.764 ± 0.035	8.971LeuLeu: 8.971 ± 0.063	2.298LeuMet: 2.298 ± 0.024	4.163LeuAsn: 4.163 ± 0.029	4.681LeuPro: 4.681 ± 0.036	4.298LeuGln: 4.298 ± 0.036	4.402LeuArg: 4.402 ± 0.031	7.145LeuSer: 7.145 ± 0.041	5.103LeuThr: 5.103 ± 0.034	5.816LeuVal: 5.816 ± 0.047	1.036LeuTrp: 1.036 ± 0.018	3.083LeuTyr: 3.083 ± 0.029	0.0LeuXaa: 0.0 ± 0.0
Met	2.068MetAla: 2.068 ± 0.023	0.321MetCys: 0.321 ± 0.009	1.683MetAsp: 1.683 ± 0.019	1.583MetGlu: 1.583 ± 0.021	0.938MetPhe: 0.938 ± 0.014	1.296MetGly: 1.296 ± 0.019	0.537MetHis: 0.537 ± 0.011	1.42MetIle: 1.42 ± 0.016	1.44MetLys: 1.44 ± 0.017	2.246MetLeu: 2.246 ± 0.024	0.824MetMet: 0.824 ± 0.014	1.209MetAsn: 1.209 ± 0.017	1.2MetPro: 1.2 ± 0.017	1.048MetGln: 1.048 ± 0.017	1.168MetArg: 1.168 ± 0.016	2.177MetSer: 2.177 ± 0.02	1.645MetThr: 1.645 ± 0.02	1.547MetVal: 1.547 ± 0.019	0.259MetTrp: 0.259 ± 0.008	0.796MetTyr: 0.796 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.539AsnAla: 3.539 ± 0.029	0.631AsnCys: 0.631 ± 0.015	2.745AsnAsp: 2.745 ± 0.026	2.673AsnGlu: 2.673 ± 0.022	1.634AsnPhe: 1.634 ± 0.021	2.558AsnGly: 2.558 ± 0.026	1.227AsnHis: 1.227 ± 0.019	2.747AsnIle: 2.747 ± 0.027	2.831AsnLys: 2.831 ± 0.027	3.864AsnLeu: 3.864 ± 0.036	1.274AsnMet: 1.274 ± 0.018	2.803AsnAsn: 2.803 ± 0.036	2.222AsnPro: 2.222 ± 0.024	2.093AsnGln: 2.093 ± 0.024	2.096AsnArg: 2.096 ± 0.022	3.353AsnSer: 3.353 ± 0.032	3.01AsnThr: 3.01 ± 0.03	2.958AsnVal: 2.958 ± 0.027	0.569AsnTrp: 0.569 ± 0.013	1.619AsnTyr: 1.619 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	3.481ProAla: 3.481 ± 0.03	0.519ProCys: 0.519 ± 0.013	2.487ProAsp: 2.487 ± 0.024	2.914ProGlu: 2.914 ± 0.028	1.923ProPhe: 1.923 ± 0.023	2.122ProGly: 2.122 ± 0.028	1.211ProHis: 1.211 ± 0.018	2.594ProIle: 2.594 ± 0.023	2.546ProLys: 2.546 ± 0.028	4.124ProLeu: 4.124 ± 0.032	0.997ProMet: 0.997 ± 0.016	2.261ProAsn: 2.261 ± 0.026	3.299ProPro: 3.299 ± 0.042	2.048ProGln: 2.048 ± 0.024	1.936ProArg: 1.936 ± 0.023	4.496ProSer: 4.496 ± 0.039	3.283ProThr: 3.283 ± 0.029	2.992ProVal: 2.992 ± 0.031	0.479ProTrp: 0.479 ± 0.011	1.535ProTyr: 1.535 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.071GlnAla: 3.071 ± 0.027	0.596GlnCys: 0.596 ± 0.013	2.763GlnAsp: 2.763 ± 0.027	2.952GlnGlu: 2.952 ± 0.027	1.736GlnPhe: 1.736 ± 0.02	2.028GlnGly: 2.028 ± 0.024	1.701GlnHis: 1.701 ± 0.024	2.311GlnIle: 2.311 ± 0.027	2.709GlnLys: 2.709 ± 0.025	4.408GlnLeu: 4.408 ± 0.036	1.1GlnMet: 1.1 ± 0.016	1.76GlnAsn: 1.76 ± 0.02	2.221GlnPro: 2.221 ± 0.028	5.003GlnGln: 5.003 ± 0.078	2.347GlnArg: 2.347 ± 0.023	3.045GlnSer: 3.045 ± 0.027	2.249GlnThr: 2.249 ± 0.024	2.76GlnVal: 2.76 ± 0.027	0.541GlnTrp: 0.541 ± 0.012	1.48GlnTyr: 1.48 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	3.113ArgAla: 3.113 ± 0.028	0.671ArgCys: 0.671 ± 0.012	2.595ArgAsp: 2.595 ± 0.026	2.743ArgGlu: 2.743 ± 0.028	2.074ArgPhe: 2.074 ± 0.022	2.331ArgGly: 2.331 ± 0.026	1.435ArgHis: 1.435 ± 0.019	2.989ArgIle: 2.989 ± 0.03	3.335ArgLys: 3.335 ± 0.029	4.778ArgLeu: 4.778 ± 0.031	1.222ArgMet: 1.222 ± 0.016	2.271ArgAsn: 2.271 ± 0.023	2.128ArgPro: 2.128 ± 0.023	2.402ArgGln: 2.402 ± 0.025	3.245ArgArg: 3.245 ± 0.037	3.533ArgSer: 3.533 ± 0.032	2.421ArgThr: 2.421 ± 0.027	2.82ArgVal: 2.82 ± 0.03	0.618ArgTrp: 0.618 ± 0.013	1.709ArgTyr: 1.709 ± 0.022	0.0ArgXaa: 0.0 ± 0.0
Ser	5.499SerAla: 5.499 ± 0.035	1.022SerCys: 1.022 ± 0.016	4.001SerAsp: 4.001 ± 0.03	3.686SerGlu: 3.686 ± 0.027	3.27SerPhe: 3.27 ± 0.03	3.972SerGly: 3.972 ± 0.036	1.866SerHis: 1.866 ± 0.022	4.817SerIle: 4.817 ± 0.036	4.546SerLys: 4.546 ± 0.032	6.87SerLeu: 6.87 ± 0.045	1.919SerMet: 1.919 ± 0.019	4.142SerAsn: 4.142 ± 0.039	3.91SerPro: 3.91 ± 0.04	3.08SerGln: 3.08 ± 0.028	3.596SerArg: 3.596 ± 0.032	9.063SerSer: 9.063 ± 0.089	5.629SerThr: 5.629 ± 0.046	4.702SerVal: 4.702 ± 0.03	0.863SerTrp: 0.863 ± 0.013	2.369SerTyr: 2.369 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	4.817ThrAla: 4.817 ± 0.035	0.909ThrCys: 0.909 ± 0.015	2.971ThrAsp: 2.971 ± 0.028	3.141ThrGlu: 3.141 ± 0.028	2.509ThrPhe: 2.509 ± 0.026	3.234ThrGly: 3.234 ± 0.03	1.484ThrHis: 1.484 ± 0.019	3.675ThrIle: 3.675 ± 0.031	3.209ThrLys: 3.209 ± 0.03	5.683ThrLeu: 5.683 ± 0.042	1.447ThrMet: 1.447 ± 0.019	2.637ThrAsn: 2.637 ± 0.025	3.348ThrPro: 3.348 ± 0.031	2.21ThrGln: 2.21 ± 0.023	2.585ThrArg: 2.585 ± 0.022	5.239ThrSer: 5.239 ± 0.039	5.096ThrThr: 5.096 ± 0.053	3.845ThrVal: 3.845 ± 0.029	0.686ThrTrp: 0.686 ± 0.013	1.787ThrTyr: 1.787 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	4.623ValAla: 4.623 ± 0.037	1.042ValCys: 1.042 ± 0.016	3.936ValAsp: 3.936 ± 0.039	3.639ValGlu: 3.639 ± 0.03	2.741ValPhe: 2.741 ± 0.029	3.35ValGly: 3.35 ± 0.03	1.566ValHis: 1.566 ± 0.02	3.717ValIle: 3.717 ± 0.027	3.612ValLys: 3.612 ± 0.033	5.812ValLeu: 5.812 ± 0.043	1.567ValMet: 1.567 ± 0.019	2.805ValAsn: 2.805 ± 0.029	2.971ValPro: 2.971 ± 0.029	2.546ValGln: 2.546 ± 0.029	2.744ValArg: 2.744 ± 0.029	4.532ValSer: 4.532 ± 0.035	3.267ValThr: 3.267 ± 0.027	4.309ValVal: 4.309 ± 0.039	0.742ValTrp: 0.742 ± 0.014	2.222ValTyr: 2.222 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	0.714TrpAla: 0.714 ± 0.012	0.199TrpCys: 0.199 ± 0.007	0.74TrpAsp: 0.74 ± 0.016	0.615TrpGlu: 0.615 ± 0.012	0.572TrpPhe: 0.572 ± 0.012	0.593TrpGly: 0.593 ± 0.012	0.312TrpHis: 0.312 ± 0.009	0.804TrpIle: 0.804 ± 0.014	0.784TrpLys: 0.784 ± 0.013	1.108TrpLeu: 1.108 ± 0.017	0.36TrpMet: 0.36 ± 0.009	0.612TrpAsn: 0.612 ± 0.012	0.407TrpPro: 0.407 ± 0.01	0.473TrpGln: 0.473 ± 0.01	0.667TrpArg: 0.667 ± 0.013	0.932TrpSer: 0.932 ± 0.014	0.726TrpThr: 0.726 ± 0.013	0.666TrpVal: 0.666 ± 0.012	0.202TrpTrp: 0.202 ± 0.007	0.415TrpTyr: 0.415 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.254TyrAla: 2.254 ± 0.024	0.67TyrCys: 0.67 ± 0.015	2.036TyrAsp: 2.036 ± 0.02	1.81TyrGlu: 1.81 ± 0.021	1.59TyrPhe: 1.59 ± 0.018	1.986TyrGly: 1.986 ± 0.022	1.003TyrHis: 1.003 ± 0.016	1.95TyrIle: 1.95 ± 0.021	1.957TyrLys: 1.957 ± 0.023	3.331TyrLeu: 3.331 ± 0.028	0.914TyrMet: 0.914 ± 0.016	1.732TyrAsn: 1.732 ± 0.023	1.507TyrPro: 1.507 ± 0.02	1.668TyrGln: 1.668 ± 0.022	1.755TyrArg: 1.755 ± 0.021	2.372TyrSer: 2.372 ± 0.026	1.995TyrThr: 1.995 ± 0.023	1.956TyrVal: 1.956 ± 0.021	0.434TyrTrp: 0.434 ± 0.011	1.497TyrTyr: 1.497 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11586 proteins (4425880 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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