Amino acid dipepetide frequency for Tortoise microvirus 58

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.193AlaAla: 1.193 ± 0.851
0.597AlaCys: 0.597 ± 0.633
3.58AlaAsp: 3.58 ± 1.196
3.58AlaGlu: 3.58 ± 1.974
4.177AlaPhe: 4.177 ± 1.621
2.983AlaGly: 2.983 ± 0.839
0.597AlaHis: 0.597 ± 0.425
2.983AlaIle: 2.983 ± 1.426
4.177AlaLys: 4.177 ± 1.897
8.353AlaLeu: 8.353 ± 2.121
0.597AlaMet: 0.597 ± 0.563
4.177AlaAsn: 4.177 ± 1.263
1.79AlaPro: 1.79 ± 1.346
2.387AlaGln: 2.387 ± 0.878
5.37AlaArg: 5.37 ± 2.222
8.95AlaSer: 8.95 ± 1.984
4.177AlaThr: 4.177 ± 2.037
5.967AlaVal: 5.967 ± 1.438
0.597AlaTrp: 0.597 ± 0.563
3.58AlaTyr: 3.58 ± 1.48
0.0AlaXaa: 0.0 ± 0.0
Cys
0.597CysAla: 0.597 ± 0.685
0.597CysCys: 0.597 ± 0.633
0.597CysAsp: 0.597 ± 0.652
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.597CysLys: 0.597 ± 0.633
1.193CysLeu: 1.193 ± 1.046
0.0CysMet: 0.0 ± 0.0
0.597CysAsn: 0.597 ± 0.633
0.0CysPro: 0.0 ± 0.0
0.597CysGln: 0.597 ± 0.633
1.79CysArg: 1.79 ± 1.461
1.193CysSer: 1.193 ± 0.909
0.0CysThr: 0.0 ± 0.0
2.387CysVal: 2.387 ± 0.664
0.0CysTrp: 0.0 ± 0.0
0.597CysTyr: 0.597 ± 0.652
0.0CysXaa: 0.0 ± 0.0
Asp
4.773AspAla: 4.773 ± 2.572
0.0AspCys: 0.0 ± 0.0
5.37AspAsp: 5.37 ± 1.838
4.177AspGlu: 4.177 ± 2.052
4.177AspPhe: 4.177 ± 1.622
7.757AspGly: 7.757 ± 1.36
0.0AspHis: 0.0 ± 0.0
8.353AspIle: 8.353 ± 2.125
3.58AspLys: 3.58 ± 1.375
1.79AspLeu: 1.79 ± 1.147
1.79AspMet: 1.79 ± 0.75
3.58AspAsn: 3.58 ± 1.864
1.193AspPro: 1.193 ± 1.011
1.79AspGln: 1.79 ± 0.474
1.193AspArg: 1.193 ± 1.303
5.37AspSer: 5.37 ± 1.385
4.773AspThr: 4.773 ± 0.999
4.773AspVal: 4.773 ± 1.57
1.193AspTrp: 1.193 ± 0.85
4.773AspTyr: 4.773 ± 0.871
0.0AspXaa: 0.0 ± 0.0
Glu
2.387GluAla: 2.387 ± 1.227
0.0GluCys: 0.0 ± 0.0
1.193GluAsp: 1.193 ± 0.534
2.387GluGlu: 2.387 ± 0.983
1.79GluPhe: 1.79 ± 0.972
0.597GluGly: 0.597 ± 0.425
1.79GluHis: 1.79 ± 1.009
2.983GluIle: 2.983 ± 0.941
1.79GluLys: 1.79 ± 0.96
4.773GluLeu: 4.773 ± 2.333
2.983GluMet: 2.983 ± 2.098
1.79GluAsn: 1.79 ± 0.96
2.983GluPro: 2.983 ± 1.269
1.193GluGln: 1.193 ± 0.892
6.563GluArg: 6.563 ± 4.096
2.983GluSer: 2.983 ± 1.463
1.79GluThr: 1.79 ± 0.764
2.387GluVal: 2.387 ± 1.225
1.193GluTrp: 1.193 ± 0.725
3.58GluTyr: 3.58 ± 1.192
0.0GluXaa: 0.0 ± 0.0
Phe
1.79PheAla: 1.79 ± 1.274
0.597PheCys: 0.597 ± 0.662
3.58PheAsp: 3.58 ± 0.963
3.58PheGlu: 3.58 ± 1.5
4.177PhePhe: 4.177 ± 2.598
5.967PheGly: 5.967 ± 1.751
1.193PheHis: 1.193 ± 0.982
1.193PheIle: 1.193 ± 0.559
1.79PheLys: 1.79 ± 0.703
4.177PheLeu: 4.177 ± 1.421
1.79PheMet: 1.79 ± 1.079
1.193PheAsn: 1.193 ± 0.559
2.387PhePro: 2.387 ± 1.699
1.193PheGln: 1.193 ± 0.88
2.387PheArg: 2.387 ± 1.118
5.37PheSer: 5.37 ± 1.22
2.983PheThr: 2.983 ± 0.839
2.983PheVal: 2.983 ± 0.784
0.0PheTrp: 0.0 ± 0.0
0.597PheTyr: 0.597 ± 0.425
0.0PheXaa: 0.0 ± 0.0
Gly
4.177GlyAla: 4.177 ± 1.408
0.597GlyCys: 0.597 ± 0.652
1.79GlyAsp: 1.79 ± 0.474
1.193GlyGlu: 1.193 ± 1.267
2.983GlyPhe: 2.983 ± 1.214
7.757GlyGly: 7.757 ± 2.751
0.597GlyHis: 0.597 ± 0.425
5.967GlyIle: 5.967 ± 3.609
2.387GlyLys: 2.387 ± 1.283
5.967GlyLeu: 5.967 ± 1.818
2.387GlyMet: 2.387 ± 0.733
1.79GlyAsn: 1.79 ± 0.684
0.0GlyPro: 0.0 ± 0.0
2.387GlyGln: 2.387 ± 0.843
2.983GlyArg: 2.983 ± 1.647
6.563GlySer: 6.563 ± 2.65
4.773GlyThr: 4.773 ± 2.284
7.16GlyVal: 7.16 ± 2.349
1.79GlyTrp: 1.79 ± 0.703
2.983GlyTyr: 2.983 ± 1.105
0.0GlyXaa: 0.0 ± 0.0
His
1.193HisAla: 1.193 ± 0.534
0.0HisCys: 0.0 ± 0.0
1.193HisAsp: 1.193 ± 0.613
1.193HisGlu: 1.193 ± 0.559
1.79HisPhe: 1.79 ± 1.135
0.597HisGly: 0.597 ± 0.685
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
0.597HisLeu: 0.597 ± 0.633
0.0HisMet: 0.0 ± 0.0
1.193HisAsn: 1.193 ± 0.559
0.597HisPro: 0.597 ± 0.685
0.597HisGln: 0.597 ± 0.563
1.193HisArg: 1.193 ± 1.267
1.193HisSer: 1.193 ± 0.88
0.597HisThr: 0.597 ± 0.425
1.79HisVal: 1.79 ± 1.461
1.79HisTrp: 1.79 ± 1.274
1.193HisTyr: 1.193 ± 0.918
0.0HisXaa: 0.0 ± 0.0
Ile
4.773IleAla: 4.773 ± 1.23
1.193IleCys: 1.193 ± 0.559
4.177IleAsp: 4.177 ± 1.194
2.387IleGlu: 2.387 ± 0.983
1.193IlePhe: 1.193 ± 0.85
4.177IleGly: 4.177 ± 0.709
0.597IleHis: 0.597 ± 0.685
1.193IleIle: 1.193 ± 0.85
0.597IleLys: 0.597 ± 0.425
1.193IleLeu: 1.193 ± 0.534
1.193IleMet: 1.193 ± 0.85
1.193IleAsn: 1.193 ± 0.534
1.79IlePro: 1.79 ± 0.679
2.387IleGln: 2.387 ± 0.733
3.58IleArg: 3.58 ± 1.15
7.16IleSer: 7.16 ± 1.622
2.983IleThr: 2.983 ± 0.784
2.387IleVal: 2.387 ± 1.227
0.597IleTrp: 0.597 ± 0.563
1.193IleTyr: 1.193 ± 0.85
0.0IleXaa: 0.0 ± 0.0
Lys
2.983LysAla: 2.983 ± 1.567
1.193LysCys: 1.193 ± 0.918
5.37LysAsp: 5.37 ± 2.634
1.79LysGlu: 1.79 ± 1.012
1.79LysPhe: 1.79 ± 1.42
0.0LysGly: 0.0 ± 0.0
1.193LysHis: 1.193 ± 0.534
1.79LysIle: 1.79 ± 0.474
2.387LysLys: 2.387 ± 2.022
3.58LysLeu: 3.58 ± 1.693
0.0LysMet: 0.0 ± 0.0
0.597LysAsn: 0.597 ± 0.633
1.193LysPro: 1.193 ± 0.85
3.58LysGln: 3.58 ± 1.375
3.58LysArg: 3.58 ± 2.363
2.387LysSer: 2.387 ± 0.936
1.79LysThr: 1.79 ± 0.703
3.58LysVal: 3.58 ± 1.291
0.0LysTrp: 0.0 ± 0.0
1.79LysTyr: 1.79 ± 1.24
0.0LysXaa: 0.0 ± 0.0
Leu
3.58LeuAla: 3.58 ± 1.565
0.0LeuCys: 0.0 ± 0.0
8.353LeuAsp: 8.353 ± 2.33
2.983LeuGlu: 2.983 ± 1.524
2.387LeuPhe: 2.387 ± 1.117
7.16LeuGly: 7.16 ± 3.056
1.79LeuHis: 1.79 ± 1.461
1.193LeuIle: 1.193 ± 0.85
5.967LeuLys: 5.967 ± 2.453
2.387LeuLeu: 2.387 ± 1.548
1.79LeuMet: 1.79 ± 0.857
1.79LeuAsn: 1.79 ± 0.784
7.757LeuPro: 7.757 ± 2.768
4.773LeuGln: 4.773 ± 1.421
7.757LeuArg: 7.757 ± 1.717
7.757LeuSer: 7.757 ± 1.115
5.37LeuThr: 5.37 ± 1.641
4.177LeuVal: 4.177 ± 0.702
1.193LeuTrp: 1.193 ± 0.534
4.177LeuTyr: 4.177 ± 1.849
0.0LeuXaa: 0.0 ± 0.0
Met
2.983MetAla: 2.983 ± 0.87
0.0MetCys: 0.0 ± 0.0
2.387MetAsp: 2.387 ± 0.843
1.79MetGlu: 1.79 ± 1.326
0.597MetPhe: 0.597 ± 0.662
1.193MetGly: 1.193 ± 0.85
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.597MetLeu: 0.597 ± 0.652
0.0MetMet: 0.0 ± 0.0
1.79MetAsn: 1.79 ± 0.684
1.193MetPro: 1.193 ± 0.534
0.597MetGln: 0.597 ± 0.652
0.0MetArg: 0.0 ± 0.0
2.983MetSer: 2.983 ± 1.535
1.193MetThr: 1.193 ± 0.851
2.387MetVal: 2.387 ± 1.142
0.597MetTrp: 0.597 ± 0.425
0.597MetTyr: 0.597 ± 0.662
0.0MetXaa: 0.0 ± 0.0
Asn
1.193AsnAla: 1.193 ± 0.534
1.193AsnCys: 1.193 ± 0.558
0.0AsnAsp: 0.0 ± 0.0
2.387AsnGlu: 2.387 ± 1.78
3.58AsnPhe: 3.58 ± 1.836
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
2.387AsnIle: 2.387 ± 0.533
2.387AsnLys: 2.387 ± 0.878
5.967AsnLeu: 5.967 ± 2.878
0.0AsnMet: 0.0 ± 0.0
1.79AsnAsn: 1.79 ± 1.339
3.58AsnPro: 3.58 ± 0.76
1.193AsnGln: 1.193 ± 0.534
2.387AsnArg: 2.387 ± 1.19
3.58AsnSer: 3.58 ± 0.909
4.773AsnThr: 4.773 ± 1.613
1.79AsnVal: 1.79 ± 1.158
0.0AsnTrp: 0.0 ± 0.0
2.983AsnTyr: 2.983 ± 1.486
0.0AsnXaa: 0.0 ± 0.0
Pro
9.547ProAla: 9.547 ± 2.294
0.597ProCys: 0.597 ± 0.633
2.387ProAsp: 2.387 ± 1.156
2.983ProGlu: 2.983 ± 1.692
2.983ProPhe: 2.983 ± 1.269
0.597ProGly: 0.597 ± 0.425
1.193ProHis: 1.193 ± 0.88
1.79ProIle: 1.79 ± 1.116
0.0ProLys: 0.0 ± 0.0
4.177ProLeu: 4.177 ± 0.923
0.597ProMet: 0.597 ± 0.425
2.983ProAsn: 2.983 ± 0.799
3.58ProPro: 3.58 ± 1.132
1.193ProGln: 1.193 ± 0.85
1.79ProArg: 1.79 ± 0.703
4.177ProSer: 4.177 ± 1.621
2.387ProThr: 2.387 ± 1.761
4.177ProVal: 4.177 ± 1.456
0.597ProTrp: 0.597 ± 0.425
1.79ProTyr: 1.79 ± 0.679
0.0ProXaa: 0.0 ± 0.0
Gln
4.177GlnAla: 4.177 ± 1.258
0.0GlnCys: 0.0 ± 0.0
2.387GlnAsp: 2.387 ± 0.733
2.983GlnGlu: 2.983 ± 1.387
2.387GlnPhe: 2.387 ± 1.142
0.597GlnGly: 0.597 ± 0.425
0.0GlnHis: 0.0 ± 0.0
1.193GlnIle: 1.193 ± 1.126
5.37GlnLys: 5.37 ± 1.616
6.563GlnLeu: 6.563 ± 0.87
0.0GlnMet: 0.0 ± 0.0
1.79GlnAsn: 1.79 ± 1.012
1.79GlnPro: 1.79 ± 0.972
1.193GlnGln: 1.193 ± 1.126
2.983GlnArg: 2.983 ± 1.021
2.983GlnSer: 2.983 ± 1.011
1.79GlnThr: 1.79 ± 1.274
0.597GlnVal: 0.597 ± 0.425
0.0GlnTrp: 0.0 ± 0.0
2.387GlnTyr: 2.387 ± 0.711
0.0GlnXaa: 0.0 ± 0.0
Arg
4.773ArgAla: 4.773 ± 1.446
1.79ArgCys: 1.79 ± 1.461
5.967ArgAsp: 5.967 ± 1.572
4.773ArgGlu: 4.773 ± 1.722
3.58ArgPhe: 3.58 ± 1.359
1.79ArgGly: 1.79 ± 1.116
1.79ArgHis: 1.79 ± 1.116
4.773ArgIle: 4.773 ± 1.744
1.193ArgLys: 1.193 ± 0.534
7.757ArgLeu: 7.757 ± 0.717
1.193ArgMet: 1.193 ± 0.85
4.177ArgAsn: 4.177 ± 1.551
3.58ArgPro: 3.58 ± 2.232
0.597ArgGln: 0.597 ± 0.425
3.58ArgArg: 3.58 ± 1.675
3.58ArgSer: 3.58 ± 1.099
1.79ArgThr: 1.79 ± 1.203
4.177ArgVal: 4.177 ± 1.391
0.597ArgTrp: 0.597 ± 0.633
4.177ArgTyr: 4.177 ± 1.805
0.0ArgXaa: 0.0 ± 0.0
Ser
8.353SerAla: 8.353 ± 1.98
0.597SerCys: 0.597 ± 0.652
4.773SerAsp: 4.773 ± 2.148
2.387SerGlu: 2.387 ± 1.142
2.387SerPhe: 2.387 ± 1.536
9.547SerGly: 9.547 ± 1.528
0.597SerHis: 0.597 ± 0.652
4.773SerIle: 4.773 ± 1.045
2.983SerLys: 2.983 ± 1.347
7.16SerLeu: 7.16 ± 1.93
0.597SerMet: 0.597 ± 0.425
3.58SerAsn: 3.58 ± 1.568
5.37SerPro: 5.37 ± 1.548
2.983SerGln: 2.983 ± 1.535
4.773SerArg: 4.773 ± 0.603
8.95SerSer: 8.95 ± 1.676
6.563SerThr: 6.563 ± 2.465
8.353SerVal: 8.353 ± 1.323
1.79SerTrp: 1.79 ± 0.954
4.177SerTyr: 4.177 ± 1.574
0.0SerXaa: 0.0 ± 0.0
Thr
5.967ThrAla: 5.967 ± 2.426
1.193ThrCys: 1.193 ± 0.88
5.37ThrAsp: 5.37 ± 1.067
1.79ThrGlu: 1.79 ± 0.684
1.79ThrPhe: 1.79 ± 0.764
6.563ThrGly: 6.563 ± 2.678
2.983ThrHis: 2.983 ± 0.956
1.193ThrIle: 1.193 ± 0.534
1.193ThrLys: 1.193 ± 1.126
4.177ThrLeu: 4.177 ± 1.289
1.79ThrMet: 1.79 ± 0.85
2.387ThrAsn: 2.387 ± 1.077
1.79ThrPro: 1.79 ± 1.346
4.773ThrGln: 4.773 ± 2.136
2.983ThrArg: 2.983 ± 1.084
7.16ThrSer: 7.16 ± 2.865
2.387ThrThr: 2.387 ± 1.103
2.983ThrVal: 2.983 ± 0.438
0.0ThrTrp: 0.0 ± 0.0
2.387ThrTyr: 2.387 ± 1.117
0.0ThrXaa: 0.0 ± 0.0
Val
3.58ValAla: 3.58 ± 2.498
0.0ValCys: 0.0 ± 0.0
4.177ValAsp: 4.177 ± 1.223
0.597ValGlu: 0.597 ± 0.633
2.983ValPhe: 2.983 ± 0.95
3.58ValGly: 3.58 ± 1.5
1.193ValHis: 1.193 ± 0.726
1.193ValIle: 1.193 ± 0.85
2.387ValLys: 2.387 ± 1.398
6.563ValLeu: 6.563 ± 2.228
1.79ValMet: 1.79 ± 0.784
1.193ValAsn: 1.193 ± 0.558
5.967ValPro: 5.967 ± 1.383
2.387ValGln: 2.387 ± 0.865
7.757ValArg: 7.757 ± 2.325
6.563ValSer: 6.563 ± 1.623
7.16ValThr: 7.16 ± 2.711
4.177ValVal: 4.177 ± 0.636
1.79ValTrp: 1.79 ± 1.274
2.983ValTyr: 2.983 ± 1.464
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.597TrpCys: 0.597 ± 0.662
1.193TrpAsp: 1.193 ± 0.726
0.0TrpGlu: 0.0 ± 0.0
1.79TrpPhe: 1.79 ± 1.274
0.597TrpGly: 0.597 ± 0.425
0.0TrpHis: 0.0 ± 0.0
0.597TrpIle: 0.597 ± 0.563
0.597TrpLys: 0.597 ± 0.633
0.597TrpLeu: 0.597 ± 0.425
0.0TrpMet: 0.0 ± 0.0
2.387TrpAsn: 2.387 ± 0.878
0.597TrpPro: 0.597 ± 0.633
1.193TrpGln: 1.193 ± 0.85
0.597TrpArg: 0.597 ± 0.425
0.0TrpSer: 0.0 ± 0.0
2.387TrpThr: 2.387 ± 1.727
0.597TrpVal: 0.597 ± 0.563
0.0TrpTrp: 0.0 ± 0.0
1.193TrpTyr: 1.193 ± 0.534
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.79TyrAla: 1.79 ± 1.274
0.0TyrCys: 0.0 ± 0.0
6.563TyrAsp: 6.563 ± 1.979
4.177TyrGlu: 4.177 ± 1.616
2.983TyrPhe: 2.983 ± 1.692
4.773TyrGly: 4.773 ± 3.186
1.193TyrHis: 1.193 ± 0.918
2.387TyrIle: 2.387 ± 1.727
1.193TyrLys: 1.193 ± 0.726
4.773TyrLeu: 4.773 ± 1.992
1.79TyrMet: 1.79 ± 1.461
1.193TyrAsn: 1.193 ± 0.85
2.387TyrPro: 2.387 ± 1.083
4.177TyrGln: 4.177 ± 1.258
2.387TyrArg: 2.387 ± 1.103
1.79TyrSer: 1.79 ± 1.274
1.193TyrThr: 1.193 ± 0.85
1.193TyrVal: 1.193 ± 0.558
1.193TyrTrp: 1.193 ± 1.267
1.193TyrTyr: 1.193 ± 0.85
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1677 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski