Amino acid dipepetide frequency for Uncinocarpus reesii (strain UAMH 1704)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.222AlaAla: 8.222 ± 0.066	0.956AlaCys: 0.956 ± 0.016	4.05AlaAsp: 4.05 ± 0.033	5.111AlaGlu: 5.111 ± 0.05	3.055AlaPhe: 3.055 ± 0.033	5.436AlaGly: 5.436 ± 0.051	1.729AlaHis: 1.729 ± 0.024	4.241AlaIle: 4.241 ± 0.04	4.191AlaLys: 4.191 ± 0.035	7.454AlaLeu: 7.454 ± 0.057	1.814AlaMet: 1.814 ± 0.021	2.946AlaAsn: 2.946 ± 0.031	4.656AlaPro: 4.656 ± 0.042	3.225AlaGln: 3.225 ± 0.036	5.013AlaArg: 5.013 ± 0.04	7.023AlaSer: 7.023 ± 0.053	4.941AlaThr: 4.941 ± 0.037	5.103AlaVal: 5.103 ± 0.04	0.991AlaTrp: 0.991 ± 0.018	1.965AlaTyr: 1.965 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.883CysAla: 0.883 ± 0.018	0.258CysCys: 0.258 ± 0.01	0.638CysAsp: 0.638 ± 0.012	0.624CysGlu: 0.624 ± 0.015	0.531CysPhe: 0.531 ± 0.014	0.903CysGly: 0.903 ± 0.018	0.339CysHis: 0.339 ± 0.009	0.678CysIle: 0.678 ± 0.012	0.521CysLys: 0.521 ± 0.013	1.282CysLeu: 1.282 ± 0.024	0.262CysMet: 0.262 ± 0.009	0.419CysAsn: 0.419 ± 0.011	0.689CysPro: 0.689 ± 0.014	0.463CysGln: 0.463 ± 0.012	0.805CysArg: 0.805 ± 0.016	0.965CysSer: 0.965 ± 0.018	0.648CysThr: 0.648 ± 0.015	0.756CysVal: 0.756 ± 0.017	0.192CysTrp: 0.192 ± 0.008	0.356CysTyr: 0.356 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.44AspAla: 4.44 ± 0.033	0.642AspCys: 0.642 ± 0.014	4.027AspAsp: 4.027 ± 0.045	4.452AspGlu: 4.452 ± 0.042	2.218AspPhe: 2.218 ± 0.027	3.934AspGly: 3.934 ± 0.036	1.216AspHis: 1.216 ± 0.019	3.327AspIle: 3.327 ± 0.031	2.364AspLys: 2.364 ± 0.028	5.034AspLeu: 5.034 ± 0.044	1.201AspMet: 1.201 ± 0.02	1.864AspAsn: 1.864 ± 0.024	3.38AspPro: 3.38 ± 0.03	1.894AspGln: 1.894 ± 0.024	3.168AspArg: 3.168 ± 0.033	4.252AspSer: 4.252 ± 0.034	2.852AspThr: 2.852 ± 0.026	3.485AspVal: 3.485 ± 0.033	0.831AspTrp: 0.831 ± 0.015	1.594AspTyr: 1.594 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	5.213GluAla: 5.213 ± 0.044	0.629GluCys: 0.629 ± 0.014	4.119GluAsp: 4.119 ± 0.044	5.467GluGlu: 5.467 ± 0.064	2.092GluPhe: 2.092 ± 0.025	3.629GluGly: 3.629 ± 0.03	1.401GluHis: 1.401 ± 0.023	3.31GluIle: 3.31 ± 0.03	3.895GluLys: 3.895 ± 0.044	5.434GluLeu: 5.434 ± 0.044	1.451GluMet: 1.451 ± 0.021	2.6GluAsn: 2.6 ± 0.032	3.057GluPro: 3.057 ± 0.04	2.574GluGln: 2.574 ± 0.031	4.159GluArg: 4.159 ± 0.04	4.59GluSer: 4.59 ± 0.044	3.564GluThr: 3.564 ± 0.035	3.4GluVal: 3.4 ± 0.028	0.852GluTrp: 0.852 ± 0.014	1.704GluTyr: 1.704 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	2.969PheAla: 2.969 ± 0.03	0.588PheCys: 0.588 ± 0.016	2.289PheAsp: 2.289 ± 0.027	2.25PheGlu: 2.25 ± 0.023	1.514PhePhe: 1.514 ± 0.024	2.799PheGly: 2.799 ± 0.034	0.916PheHis: 0.916 ± 0.018	1.789PheIle: 1.789 ± 0.027	1.618PheLys: 1.618 ± 0.023	3.458PheLeu: 3.458 ± 0.037	0.761PheMet: 0.761 ± 0.014	1.478PheAsn: 1.478 ± 0.022	2.083PhePro: 2.083 ± 0.025	1.446PheGln: 1.446 ± 0.018	2.109PheArg: 2.109 ± 0.025	3.17PheSer: 3.17 ± 0.03	2.076PheThr: 2.076 ± 0.027	2.278PheVal: 2.278 ± 0.025	0.57PheTrp: 0.57 ± 0.014	1.07PheTyr: 1.07 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	4.898GlyAla: 4.898 ± 0.044	0.852GlyCys: 0.852 ± 0.019	3.591GlyAsp: 3.591 ± 0.031	3.724GlyGlu: 3.724 ± 0.035	2.693GlyPhe: 2.693 ± 0.029	5.302GlyGly: 5.302 ± 0.058	1.62GlyHis: 1.62 ± 0.025	3.522GlyIle: 3.522 ± 0.034	3.55GlyLys: 3.55 ± 0.034	5.802GlyLeu: 5.802 ± 0.046	1.554GlyMet: 1.554 ± 0.022	2.569GlyAsn: 2.569 ± 0.026	3.316GlyPro: 3.316 ± 0.037	2.482GlyGln: 2.482 ± 0.029	4.189GlyArg: 4.189 ± 0.037	5.58GlySer: 5.58 ± 0.051	3.75GlyThr: 3.75 ± 0.035	4.049GlyVal: 4.049 ± 0.039	1.065GlyTrp: 1.065 ± 0.018	2.007GlyTyr: 2.007 ± 0.028	0.0GlyXaa: 0.0 ± 0.0
His	1.786HisAla: 1.786 ± 0.024	0.333HisCys: 0.333 ± 0.01	1.306HisAsp: 1.306 ± 0.021	1.309HisGlu: 1.309 ± 0.02	0.967HisPhe: 0.967 ± 0.019	1.75HisGly: 1.75 ± 0.024	0.839HisHis: 0.839 ± 0.021	1.266HisIle: 1.266 ± 0.019	0.952HisLys: 0.952 ± 0.02	2.28HisLeu: 2.28 ± 0.026	0.463HisMet: 0.463 ± 0.011	0.86HisAsn: 0.86 ± 0.015	1.759HisPro: 1.759 ± 0.021	1.023HisGln: 1.023 ± 0.018	1.686HisArg: 1.686 ± 0.021	1.977HisSer: 1.977 ± 0.028	1.256HisThr: 1.256 ± 0.015	1.371HisVal: 1.371 ± 0.021	0.32HisTrp: 0.32 ± 0.01	0.657HisTyr: 0.657 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.081IleAla: 4.081 ± 0.038	0.761IleCys: 0.761 ± 0.015	2.948IleAsp: 2.948 ± 0.033	2.979IleGlu: 2.979 ± 0.03	2.032IlePhe: 2.032 ± 0.025	3.04IleGly: 3.04 ± 0.028	1.264IleHis: 1.264 ± 0.019	2.55IleIle: 2.55 ± 0.031	2.377IleLys: 2.377 ± 0.028	4.8IleLeu: 4.8 ± 0.042	1.005IleMet: 1.005 ± 0.016	1.826IleAsn: 1.826 ± 0.021	3.398IlePro: 3.398 ± 0.034	2.01IleGln: 2.01 ± 0.026	3.062IleArg: 3.062 ± 0.029	4.319IleSer: 4.319 ± 0.034	2.782IleThr: 2.782 ± 0.028	3.102IleVal: 3.102 ± 0.033	0.68IleTrp: 0.68 ± 0.015	1.408IleTyr: 1.408 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	4.292LysAla: 4.292 ± 0.041	0.522LysCys: 0.522 ± 0.012	2.861LysAsp: 2.861 ± 0.031	3.596LysGlu: 3.596 ± 0.041	1.599LysPhe: 1.599 ± 0.023	3.041LysGly: 3.041 ± 0.028	1.181LysHis: 1.181 ± 0.02	2.46LysIle: 2.46 ± 0.027	3.496LysLys: 3.496 ± 0.051	4.408LysLeu: 4.408 ± 0.028	1.055LysMet: 1.055 ± 0.019	1.777LysAsn: 1.777 ± 0.022	3.043LysPro: 3.043 ± 0.037	2.061LysGln: 2.061 ± 0.027	3.863LysArg: 3.863 ± 0.036	3.818LysSer: 3.818 ± 0.038	2.779LysThr: 2.779 ± 0.03	2.834LysVal: 2.834 ± 0.031	0.662LysTrp: 0.662 ± 0.013	1.466LysTyr: 1.466 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	7.557LeuAla: 7.557 ± 0.052	1.215LeuCys: 1.215 ± 0.018	5.26LeuAsp: 5.26 ± 0.039	5.83LeuGlu: 5.83 ± 0.051	3.319LeuPhe: 3.319 ± 0.035	5.758LeuGly: 5.758 ± 0.042	2.317LeuHis: 2.317 ± 0.024	3.92LeuIle: 3.92 ± 0.04	4.549LeuLys: 4.549 ± 0.038	8.465LeuLeu: 8.465 ± 0.072	1.702LeuMet: 1.702 ± 0.025	3.379LeuAsn: 3.379 ± 0.029	5.628LeuPro: 5.628 ± 0.045	3.898LeuGln: 3.898 ± 0.036	6.004LeuArg: 6.004 ± 0.04	7.66LeuSer: 7.66 ± 0.054	4.709LeuThr: 4.709 ± 0.04	5.291LeuVal: 5.291 ± 0.038	1.117LeuTrp: 1.117 ± 0.019	2.328LeuTyr: 2.328 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.175MetAla: 2.175 ± 0.024	0.234MetCys: 0.234 ± 0.008	1.242MetAsp: 1.242 ± 0.018	1.378MetGlu: 1.378 ± 0.022	0.706MetPhe: 0.706 ± 0.015	1.423MetGly: 1.423 ± 0.02	0.446MetHis: 0.446 ± 0.012	0.976MetIle: 0.976 ± 0.016	1.078MetLys: 1.078 ± 0.014	1.806MetLeu: 1.806 ± 0.022	0.499MetMet: 0.499 ± 0.016	0.776MetAsn: 0.776 ± 0.015	1.202MetPro: 1.202 ± 0.021	0.814MetGln: 0.814 ± 0.016	1.246MetArg: 1.246 ± 0.017	1.748MetSer: 1.748 ± 0.02	1.187MetThr: 1.187 ± 0.017	1.268MetVal: 1.268 ± 0.018	0.248MetTrp: 0.248 ± 0.008	0.477MetTyr: 0.477 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.131AsnAla: 3.131 ± 0.028	0.475AsnCys: 0.475 ± 0.012	2.04AsnAsp: 2.04 ± 0.023	2.162AsnGlu: 2.162 ± 0.024	1.369AsnPhe: 1.369 ± 0.021	2.972AsnGly: 2.972 ± 0.036	0.901AsnHis: 0.901 ± 0.016	2.187AsnIle: 2.187 ± 0.024	1.621AsnLys: 1.621 ± 0.02	3.379AsnLeu: 3.379 ± 0.033	0.822AsnMet: 0.822 ± 0.014	1.493AsnAsn: 1.493 ± 0.021	2.695AsnPro: 2.695 ± 0.029	1.463AsnGln: 1.463 ± 0.021	2.177AsnArg: 2.177 ± 0.026	2.904AsnSer: 2.904 ± 0.03	2.148AsnThr: 2.148 ± 0.025	2.314AsnVal: 2.314 ± 0.025	0.531AsnTrp: 0.531 ± 0.012	0.987AsnTyr: 0.987 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.082ProAla: 5.082 ± 0.044	0.582ProCys: 0.582 ± 0.013	3.274ProAsp: 3.274 ± 0.034	3.968ProGlu: 3.968 ± 0.04	2.199ProPhe: 2.199 ± 0.026	3.977ProGly: 3.977 ± 0.034	1.44ProHis: 1.44 ± 0.024	2.775ProIle: 2.775 ± 0.031	2.991ProLys: 2.991 ± 0.034	5.031ProLeu: 5.031 ± 0.038	1.084ProMet: 1.084 ± 0.022	2.437ProAsn: 2.437 ± 0.026	5.675ProPro: 5.675 ± 0.095	2.622ProGln: 2.622 ± 0.037	3.7ProArg: 3.7 ± 0.043	6.464ProSer: 6.464 ± 0.059	4.024ProThr: 4.024 ± 0.038	3.647ProVal: 3.647 ± 0.034	0.689ProTrp: 0.689 ± 0.013	1.467ProTyr: 1.467 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.354GlnAla: 3.354 ± 0.039	0.438GlnCys: 0.438 ± 0.013	1.951GlnAsp: 1.951 ± 0.028	2.427GlnGlu: 2.427 ± 0.028	1.375GlnPhe: 1.375 ± 0.018	2.345GlnGly: 2.345 ± 0.025	1.095GlnHis: 1.095 ± 0.018	1.978GlnIle: 1.978 ± 0.023	2.163GlnLys: 2.163 ± 0.026	3.622GlnLeu: 3.622 ± 0.034	0.86GlnMet: 0.86 ± 0.015	1.713GlnAsn: 1.713 ± 0.024	2.755GlnPro: 2.755 ± 0.039	2.303GlnGln: 2.303 ± 0.048	2.806GlnArg: 2.806 ± 0.032	3.299GlnSer: 3.299 ± 0.036	2.305GlnThr: 2.305 ± 0.026	2.073GlnVal: 2.073 ± 0.025	0.5GlnTrp: 0.5 ± 0.012	1.124GlnTyr: 1.124 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.842ArgAla: 4.842 ± 0.039	0.77ArgCys: 0.77 ± 0.017	3.48ArgAsp: 3.48 ± 0.036	4.106ArgGlu: 4.106 ± 0.044	2.301ArgPhe: 2.301 ± 0.025	3.84ArgGly: 3.84 ± 0.043	1.666ArgHis: 1.666 ± 0.022	3.193ArgIle: 3.193 ± 0.03	3.775ArgLys: 3.775 ± 0.033	5.765ArgLeu: 5.765 ± 0.04	1.368ArgMet: 1.368 ± 0.018	2.529ArgAsn: 2.529 ± 0.028	3.769ArgPro: 3.769 ± 0.041	2.766ArgGln: 2.766 ± 0.028	5.583ArgArg: 5.583 ± 0.057	5.185ArgSer: 5.185 ± 0.044	3.458ArgThr: 3.458 ± 0.032	3.46ArgVal: 3.46 ± 0.034	0.92ArgTrp: 0.92 ± 0.016	1.708ArgTyr: 1.708 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	6.522SerAla: 6.522 ± 0.047	0.892SerCys: 0.892 ± 0.017	4.221SerAsp: 4.221 ± 0.035	4.417SerGlu: 4.417 ± 0.042	3.125SerPhe: 3.125 ± 0.029	5.475SerGly: 5.475 ± 0.042	2.124SerHis: 2.124 ± 0.027	4.172SerIle: 4.172 ± 0.044	4.117SerLys: 4.117 ± 0.043	7.546SerLeu: 7.546 ± 0.049	1.72SerMet: 1.72 ± 0.024	3.204SerAsn: 3.204 ± 0.029	5.987SerPro: 5.987 ± 0.067	3.506SerGln: 3.506 ± 0.035	5.633SerArg: 5.633 ± 0.044	8.978SerSer: 8.978 ± 0.076	5.584SerThr: 5.584 ± 0.048	4.464SerVal: 4.464 ± 0.035	1.045SerTrp: 1.045 ± 0.018	1.999SerTyr: 1.999 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	4.897ThrAla: 4.897 ± 0.035	0.678ThrCys: 0.678 ± 0.015	2.744ThrAsp: 2.744 ± 0.03	3.13ThrGlu: 3.13 ± 0.032	2.158ThrPhe: 2.158 ± 0.025	4.043ThrGly: 4.043 ± 0.039	1.253ThrHis: 1.253 ± 0.019	2.986ThrIle: 2.986 ± 0.031	2.704ThrLys: 2.704 ± 0.033	5.089ThrLeu: 5.089 ± 0.04	1.157ThrMet: 1.157 ± 0.016	2.065ThrAsn: 2.065 ± 0.025	4.359ThrPro: 4.359 ± 0.041	2.058ThrGln: 2.058 ± 0.025	3.25ThrArg: 3.25 ± 0.028	5.177ThrSer: 5.177 ± 0.043	3.899ThrThr: 3.899 ± 0.048	3.615ThrVal: 3.615 ± 0.038	0.746ThrTrp: 0.746 ± 0.017	1.431ThrTyr: 1.431 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	4.795ValAla: 4.795 ± 0.038	0.8ValCys: 0.8 ± 0.018	3.666ValAsp: 3.666 ± 0.029	3.891ValGlu: 3.891 ± 0.034	2.307ValPhe: 2.307 ± 0.03	3.754ValGly: 3.754 ± 0.037	1.341ValHis: 1.341 ± 0.019	2.939ValIle: 2.939 ± 0.031	2.967ValLys: 2.967 ± 0.03	5.347ValLeu: 5.347 ± 0.048	1.243ValMet: 1.243 ± 0.019	2.203ValAsn: 2.203 ± 0.024	3.588ValPro: 3.588 ± 0.032	2.27ValGln: 2.27 ± 0.026	3.453ValArg: 3.453 ± 0.036	4.571ValSer: 4.571 ± 0.039	3.277ValThr: 3.277 ± 0.034	3.938ValVal: 3.938 ± 0.039	0.772ValTrp: 0.772 ± 0.016	1.627ValTyr: 1.627 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.04TrpAla: 1.04 ± 0.019	0.181TrpCys: 0.181 ± 0.008	0.84TrpAsp: 0.84 ± 0.017	0.828TrpGlu: 0.828 ± 0.015	0.497TrpPhe: 0.497 ± 0.012	0.817TrpGly: 0.817 ± 0.016	0.322TrpHis: 0.322 ± 0.01	0.713TrpIle: 0.713 ± 0.014	0.8TrpLys: 0.8 ± 0.015	1.251TrpLeu: 1.251 ± 0.02	0.339TrpMet: 0.339 ± 0.009	0.594TrpAsn: 0.594 ± 0.014	0.567TrpPro: 0.567 ± 0.014	0.5TrpGln: 0.5 ± 0.012	0.932TrpArg: 0.932 ± 0.018	0.983TrpSer: 0.983 ± 0.018	0.774TrpThr: 0.774 ± 0.013	0.781TrpVal: 0.781 ± 0.015	0.249TrpTrp: 0.249 ± 0.01	0.369TrpTyr: 0.369 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.942TyrAla: 1.942 ± 0.025	0.403TyrCys: 0.403 ± 0.011	1.628TyrAsp: 1.628 ± 0.023	1.49TyrGlu: 1.49 ± 0.024	1.175TyrPhe: 1.175 ± 0.018	1.877TyrGly: 1.877 ± 0.026	0.751TyrHis: 0.751 ± 0.014	1.44TyrIle: 1.44 ± 0.021	1.088TyrLys: 1.088 ± 0.019	2.651TyrLeu: 2.651 ± 0.033	0.569TyrMet: 0.569 ± 0.01	1.04TyrAsn: 1.04 ± 0.017	1.523TyrPro: 1.523 ± 0.021	1.108TyrGln: 1.108 ± 0.018	1.647TyrArg: 1.647 ± 0.023	2.069TyrSer: 2.069 ± 0.025	1.425TyrThr: 1.425 ± 0.02	1.519TyrVal: 1.519 ± 0.023	0.397TyrTrp: 0.397 ± 0.011	0.861TyrTyr: 0.861 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7760 proteins (3724661 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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