Amino acid dipepetide frequency for Tardibacter chloracetimidivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.199AlaAla: 18.199 ± 0.198	1.06AlaCys: 1.06 ± 0.033	7.545AlaAsp: 7.545 ± 0.087	7.868AlaGlu: 7.868 ± 0.108	4.219AlaPhe: 4.219 ± 0.072	10.662AlaGly: 10.662 ± 0.099	2.416AlaHis: 2.416 ± 0.046	6.364AlaIle: 6.364 ± 0.085	3.775AlaLys: 3.775 ± 0.075	13.183AlaLeu: 13.183 ± 0.129	3.773AlaMet: 3.773 ± 0.072	2.99AlaAsn: 2.99 ± 0.065	5.693AlaPro: 5.693 ± 0.081	4.082AlaGln: 4.082 ± 0.071	9.906AlaArg: 9.906 ± 0.123	6.783AlaSer: 6.783 ± 0.085	6.169AlaThr: 6.169 ± 0.081	8.708AlaVal: 8.708 ± 0.11	1.598AlaTrp: 1.598 ± 0.044	2.612AlaTyr: 2.612 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	1.049CysAla: 1.049 ± 0.034	0.1CysCys: 0.1 ± 0.01	0.576CysAsp: 0.576 ± 0.025	0.46CysGlu: 0.46 ± 0.022	0.329CysPhe: 0.329 ± 0.014	0.96CysGly: 0.96 ± 0.031	0.242CysHis: 0.242 ± 0.015	0.385CysIle: 0.385 ± 0.018	0.19CysLys: 0.19 ± 0.013	0.72CysLeu: 0.72 ± 0.026	0.169CysMet: 0.169 ± 0.013	0.232CysAsn: 0.232 ± 0.014	0.535CysPro: 0.535 ± 0.021	0.215CysGln: 0.215 ± 0.013	0.68CysArg: 0.68 ± 0.029	0.46CysSer: 0.46 ± 0.021	0.414CysThr: 0.414 ± 0.016	0.613CysVal: 0.613 ± 0.024	0.134CysTrp: 0.134 ± 0.01	0.193CysTyr: 0.193 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.323AspAla: 7.323 ± 0.093	0.519AspCys: 0.519 ± 0.026	3.546AspAsp: 3.546 ± 0.066	3.754AspGlu: 3.754 ± 0.062	2.213AspPhe: 2.213 ± 0.046	5.365AspGly: 5.365 ± 0.082	1.332AspHis: 1.332 ± 0.039	2.97AspIle: 2.97 ± 0.051	1.629AspLys: 1.629 ± 0.038	5.856AspLeu: 5.856 ± 0.08	1.47AspMet: 1.47 ± 0.034	1.353AspAsn: 1.353 ± 0.038	3.589AspPro: 3.589 ± 0.047	1.885AspGln: 1.885 ± 0.042	4.983AspArg: 4.983 ± 0.075	2.39AspSer: 2.39 ± 0.043	2.554AspThr: 2.554 ± 0.048	4.319AspVal: 4.319 ± 0.063	1.083AspTrp: 1.083 ± 0.032	1.608AspTyr: 1.608 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	8.073GluAla: 8.073 ± 0.108	0.418GluCys: 0.418 ± 0.022	2.946GluAsp: 2.946 ± 0.06	3.285GluGlu: 3.285 ± 0.062	1.533GluPhe: 1.533 ± 0.042	4.588GluGly: 4.588 ± 0.065	1.191GluHis: 1.191 ± 0.036	3.241GluIle: 3.241 ± 0.062	2.107GluLys: 2.107 ± 0.049	5.497GluLeu: 5.497 ± 0.077	1.517GluMet: 1.517 ± 0.038	1.477GluAsn: 1.477 ± 0.042	2.67GluPro: 2.67 ± 0.057	2.225GluGln: 2.225 ± 0.051	5.4GluArg: 5.4 ± 0.084	2.568GluSer: 2.568 ± 0.041	3.206GluThr: 3.206 ± 0.063	3.894GluVal: 3.894 ± 0.065	0.867GluTrp: 0.867 ± 0.034	1.068GluTyr: 1.068 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.312PheAla: 4.312 ± 0.071	0.389PheCys: 0.389 ± 0.02	2.587PheAsp: 2.587 ± 0.055	2.058PheGlu: 2.058 ± 0.045	1.198PhePhe: 1.198 ± 0.039	3.473PheGly: 3.473 ± 0.054	0.77PheHis: 0.77 ± 0.029	1.564PheIle: 1.564 ± 0.045	0.901PheLys: 0.901 ± 0.031	3.039PheLeu: 3.039 ± 0.051	0.763PheMet: 0.763 ± 0.026	1.063PheAsn: 1.063 ± 0.035	1.532PhePro: 1.532 ± 0.046	1.022PheGln: 1.022 ± 0.029	2.233PheArg: 2.233 ± 0.045	2.064PheSer: 2.064 ± 0.044	1.902PheThr: 1.902 ± 0.048	2.501PheVal: 2.501 ± 0.052	0.513PheTrp: 0.513 ± 0.023	0.834PheTyr: 0.834 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	9.369GlyAla: 9.369 ± 0.095	0.824GlyCys: 0.824 ± 0.027	4.855GlyAsp: 4.855 ± 0.065	4.981GlyGlu: 4.981 ± 0.073	3.539GlyPhe: 3.539 ± 0.059	8.01GlyGly: 8.01 ± 0.123	1.972GlyHis: 1.972 ± 0.048	4.349GlyIle: 4.349 ± 0.069	3.266GlyLys: 3.266 ± 0.063	8.602GlyLeu: 8.602 ± 0.096	2.268GlyMet: 2.268 ± 0.046	2.214GlyAsn: 2.214 ± 0.052	3.55GlyPro: 3.55 ± 0.057	2.897GlyGln: 2.897 ± 0.051	6.844GlyArg: 6.844 ± 0.087	4.936GlySer: 4.936 ± 0.073	4.403GlyThr: 4.403 ± 0.077	6.154GlyVal: 6.154 ± 0.08	1.571GlyTrp: 1.571 ± 0.04	2.332GlyTyr: 2.332 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.435HisAla: 2.435 ± 0.059	0.242HisCys: 0.242 ± 0.015	1.221HisAsp: 1.221 ± 0.034	1.113HisGlu: 1.113 ± 0.036	0.803HisPhe: 0.803 ± 0.03	2.009HisGly: 2.009 ± 0.052	0.655HisHis: 0.655 ± 0.028	0.983HisIle: 0.983 ± 0.026	0.482HisLys: 0.482 ± 0.023	2.023HisLeu: 2.023 ± 0.042	0.504HisMet: 0.504 ± 0.023	0.516HisAsn: 0.516 ± 0.02	1.35HisPro: 1.35 ± 0.04	0.598HisGln: 0.598 ± 0.022	1.656HisArg: 1.656 ± 0.042	1.019HisSer: 1.019 ± 0.035	0.751HisThr: 0.751 ± 0.028	1.529HisVal: 1.529 ± 0.037	0.372HisTrp: 0.372 ± 0.018	0.582HisTyr: 0.582 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	7.433IleAla: 7.433 ± 0.087	0.46IleCys: 0.46 ± 0.023	3.82IleAsp: 3.82 ± 0.065	3.577IleGlu: 3.577 ± 0.062	1.579IlePhe: 1.579 ± 0.04	4.942IleGly: 4.942 ± 0.071	0.887IleHis: 0.887 ± 0.028	2.236IleIle: 2.236 ± 0.054	1.287IleLys: 1.287 ± 0.039	3.848IleLeu: 3.848 ± 0.061	0.915IleMet: 0.915 ± 0.031	1.431IleAsn: 1.431 ± 0.039	2.103IlePro: 2.103 ± 0.049	1.194IleGln: 1.194 ± 0.031	3.57IleArg: 3.57 ± 0.055	2.919IleSer: 2.919 ± 0.059	2.601IleThr: 2.601 ± 0.053	3.961IleVal: 3.961 ± 0.064	0.605IleTrp: 0.605 ± 0.026	1.097IleTyr: 1.097 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.107LysAla: 4.107 ± 0.078	0.171LysCys: 0.171 ± 0.012	1.567LysAsp: 1.567 ± 0.037	1.444LysGlu: 1.444 ± 0.037	0.752LysPhe: 0.752 ± 0.029	2.597LysGly: 2.597 ± 0.053	0.636LysHis: 0.636 ± 0.025	1.504LysIle: 1.504 ± 0.04	1.089LysLys: 1.089 ± 0.035	3.151LysLeu: 3.151 ± 0.065	0.741LysMet: 0.741 ± 0.027	0.74LysAsn: 0.74 ± 0.029	1.913LysPro: 1.913 ± 0.038	0.995LysGln: 0.995 ± 0.035	2.435LysArg: 2.435 ± 0.058	1.67LysSer: 1.67 ± 0.04	1.751LysThr: 1.751 ± 0.049	2.215LysVal: 2.215 ± 0.056	0.431LysTrp: 0.431 ± 0.022	0.601LysTyr: 0.601 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	13.323LeuAla: 13.323 ± 0.129	0.876LeuCys: 0.876 ± 0.026	6.204LeuAsp: 6.204 ± 0.086	5.198LeuGlu: 5.198 ± 0.083	3.351LeuPhe: 3.351 ± 0.061	8.39LeuGly: 8.39 ± 0.096	1.858LeuHis: 1.858 ± 0.048	4.734LeuIle: 4.734 ± 0.064	3.418LeuLys: 3.418 ± 0.059	9.005LeuLeu: 9.005 ± 0.125	2.171LeuMet: 2.171 ± 0.052	2.557LeuAsn: 2.557 ± 0.053	5.418LeuPro: 5.418 ± 0.074	2.663LeuGln: 2.663 ± 0.047	6.956LeuArg: 6.956 ± 0.084	6.324LeuSer: 6.324 ± 0.084	5.259LeuThr: 5.259 ± 0.075	7.04LeuVal: 7.04 ± 0.095	1.233LeuTrp: 1.233 ± 0.039	1.887LeuTyr: 1.887 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	3.218MetAla: 3.218 ± 0.066	0.165MetCys: 0.165 ± 0.012	1.167MetAsp: 1.167 ± 0.034	1.201MetGlu: 1.201 ± 0.034	0.752MetPhe: 0.752 ± 0.025	1.95MetGly: 1.95 ± 0.047	0.436MetHis: 0.436 ± 0.02	1.35MetIle: 1.35 ± 0.029	0.944MetLys: 0.944 ± 0.033	2.574MetLeu: 2.574 ± 0.053	0.699MetMet: 0.699 ± 0.029	0.699MetAsn: 0.699 ± 0.029	1.456MetPro: 1.456 ± 0.038	0.726MetGln: 0.726 ± 0.026	1.866MetArg: 1.866 ± 0.043	1.487MetSer: 1.487 ± 0.042	1.786MetThr: 1.786 ± 0.048	1.629MetVal: 1.629 ± 0.038	0.245MetTrp: 0.245 ± 0.015	0.278MetTyr: 0.278 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.294AsnAla: 3.294 ± 0.054	0.235AsnCys: 0.235 ± 0.016	1.444AsnAsp: 1.444 ± 0.038	1.218AsnGlu: 1.218 ± 0.036	0.897AsnPhe: 0.897 ± 0.033	2.36AsnGly: 2.36 ± 0.047	0.496AsnHis: 0.496 ± 0.022	1.329AsnIle: 1.329 ± 0.034	0.631AsnLys: 0.631 ± 0.027	2.549AsnLeu: 2.549 ± 0.052	0.64AsnMet: 0.64 ± 0.024	0.68AsnAsn: 0.68 ± 0.03	1.699AsnPro: 1.699 ± 0.043	0.763AsnGln: 0.763 ± 0.029	1.926AsnArg: 1.926 ± 0.044	1.292AsnSer: 1.292 ± 0.038	1.165AsnThr: 1.165 ± 0.037	1.973AsnVal: 1.973 ± 0.037	0.45AsnTrp: 0.45 ± 0.019	0.723AsnTyr: 0.723 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	6.429ProAla: 6.429 ± 0.094	0.372ProCys: 0.372 ± 0.021	3.781ProAsp: 3.781 ± 0.064	3.657ProGlu: 3.657 ± 0.06	1.872ProPhe: 1.872 ± 0.041	4.564ProGly: 4.564 ± 0.074	1.102ProHis: 1.102 ± 0.035	2.245ProIle: 2.245 ± 0.049	1.528ProLys: 1.528 ± 0.037	4.859ProLeu: 4.859 ± 0.072	1.19ProMet: 1.19 ± 0.039	1.244ProAsn: 1.244 ± 0.032	2.969ProPro: 2.969 ± 0.075	1.639ProGln: 1.639 ± 0.04	3.15ProArg: 3.15 ± 0.057	2.839ProSer: 2.839 ± 0.048	2.453ProThr: 2.453 ± 0.053	4.207ProVal: 4.207 ± 0.066	0.721ProTrp: 0.721 ± 0.027	1.118ProTyr: 1.118 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	4.076GlnAla: 4.076 ± 0.061	0.246GlnCys: 0.246 ± 0.015	1.429GlnAsp: 1.429 ± 0.04	1.441GlnGlu: 1.441 ± 0.038	1.08GlnPhe: 1.08 ± 0.035	2.471GlnGly: 2.471 ± 0.048	0.64GlnHis: 0.64 ± 0.026	1.814GlnIle: 1.814 ± 0.04	0.959GlnLys: 0.959 ± 0.033	3.087GlnLeu: 3.087 ± 0.051	0.919GlnMet: 0.919 ± 0.028	0.814GlnAsn: 0.814 ± 0.032	1.943GlnPro: 1.943 ± 0.045	1.169GlnGln: 1.169 ± 0.039	2.599GlnArg: 2.599 ± 0.05	1.819GlnSer: 1.819 ± 0.048	1.66GlnThr: 1.66 ± 0.042	2.182GlnVal: 2.182 ± 0.051	0.465GlnTrp: 0.465 ± 0.021	0.595GlnTyr: 0.595 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	8.893ArgAla: 8.893 ± 0.107	0.654ArgCys: 0.654 ± 0.026	4.25ArgAsp: 4.25 ± 0.068	4.414ArgGlu: 4.414 ± 0.076	3.042ArgPhe: 3.042 ± 0.056	5.122ArgGly: 5.122 ± 0.067	1.817ArgHis: 1.817 ± 0.046	4.176ArgIle: 4.176 ± 0.063	2.383ArgLys: 2.383 ± 0.047	8.734ArgLeu: 8.734 ± 0.099	1.999ArgMet: 1.999 ± 0.044	2.025ArgAsn: 2.025 ± 0.045	3.88ArgPro: 3.88 ± 0.07	2.884ArgGln: 2.884 ± 0.052	6.327ArgArg: 6.327 ± 0.1	4.059ArgSer: 4.059 ± 0.064	3.704ArgThr: 3.704 ± 0.065	4.966ArgVal: 4.966 ± 0.068	1.244ArgTrp: 1.244 ± 0.03	2.044ArgTyr: 2.044 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	6.636SerAla: 6.636 ± 0.082	0.489SerCys: 0.489 ± 0.023	3.206SerAsp: 3.206 ± 0.057	2.857SerGlu: 2.857 ± 0.054	2.328SerPhe: 2.328 ± 0.05	5.66SerGly: 5.66 ± 0.077	1.076SerHis: 1.076 ± 0.043	2.853SerIle: 2.853 ± 0.053	1.474SerLys: 1.474 ± 0.038	5.193SerLeu: 5.193 ± 0.066	1.345SerMet: 1.345 ± 0.032	1.317SerAsn: 1.317 ± 0.036	2.894SerPro: 2.894 ± 0.049	1.601SerGln: 1.601 ± 0.045	3.91SerArg: 3.91 ± 0.068	3.067SerSer: 3.067 ± 0.058	2.698SerThr: 2.698 ± 0.054	3.898SerVal: 3.898 ± 0.064	0.828SerTrp: 0.828 ± 0.029	1.465SerTyr: 1.465 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	6.248ThrAla: 6.248 ± 0.086	0.416ThrCys: 0.416 ± 0.019	2.897ThrAsp: 2.897 ± 0.056	2.451ThrGlu: 2.451 ± 0.046	1.685ThrPhe: 1.685 ± 0.041	5.274ThrGly: 5.274 ± 0.076	0.974ThrHis: 0.974 ± 0.027	2.946ThrIle: 2.946 ± 0.05	1.311ThrLys: 1.311 ± 0.04	5.365ThrLeu: 5.365 ± 0.076	1.107ThrMet: 1.107 ± 0.031	1.303ThrAsn: 1.303 ± 0.033	3.291ThrPro: 3.291 ± 0.057	1.473ThrGln: 1.473 ± 0.044	3.423ThrArg: 3.423 ± 0.05	2.832ThrSer: 2.832 ± 0.062	2.623ThrThr: 2.623 ± 0.063	3.995ThrVal: 3.995 ± 0.06	0.571ThrTrp: 0.571 ± 0.026	1.13ThrTyr: 1.13 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	9.201ValAla: 9.201 ± 0.095	0.591ValCys: 0.591 ± 0.022	4.499ValAsp: 4.499 ± 0.066	4.802ValGlu: 4.802 ± 0.076	2.221ValPhe: 2.221 ± 0.048	5.42ValGly: 5.42 ± 0.088	1.452ValHis: 1.452 ± 0.038	3.866ValIle: 3.866 ± 0.063	2.082ValLys: 2.082 ± 0.047	6.619ValLeu: 6.619 ± 0.09	1.601ValMet: 1.601 ± 0.04	2.014ValAsn: 2.014 ± 0.049	3.715ValPro: 3.715 ± 0.063	2.076ValGln: 2.076 ± 0.046	5.373ValArg: 5.373 ± 0.071	4.158ValSer: 4.158 ± 0.062	4.392ValThr: 4.392 ± 0.062	5.291ValVal: 5.291 ± 0.087	0.829ValTrp: 0.829 ± 0.028	1.413ValTyr: 1.413 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.371TrpAla: 1.371 ± 0.035	0.166TrpCys: 0.166 ± 0.011	0.691TrpAsp: 0.691 ± 0.028	0.686TrpGlu: 0.686 ± 0.026	0.49TrpPhe: 0.49 ± 0.02	0.937TrpGly: 0.937 ± 0.029	0.335TrpHis: 0.335 ± 0.019	0.681TrpIle: 0.681 ± 0.027	0.509TrpLys: 0.509 ± 0.021	1.779TrpLeu: 1.779 ± 0.044	0.417TrpMet: 0.417 ± 0.021	0.479TrpAsn: 0.479 ± 0.021	0.736TrpPro: 0.736 ± 0.028	0.576TrpGln: 0.576 ± 0.022	1.36TrpArg: 1.36 ± 0.037	0.89TrpSer: 0.89 ± 0.032	0.839TrpThr: 0.839 ± 0.031	0.859TrpVal: 0.859 ± 0.029	0.242TrpTrp: 0.242 ± 0.015	0.29TrpTyr: 0.29 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.615TyrAla: 2.615 ± 0.051	0.262TyrCys: 0.262 ± 0.018	1.513TyrAsp: 1.513 ± 0.044	1.307TyrGlu: 1.307 ± 0.037	0.837TyrPhe: 0.837 ± 0.029	2.18TyrGly: 2.18 ± 0.051	0.557TyrHis: 0.557 ± 0.023	0.877TyrIle: 0.877 ± 0.03	0.547TyrLys: 0.547 ± 0.022	2.179TyrLeu: 2.179 ± 0.047	0.417TyrMet: 0.417 ± 0.02	0.615TyrAsn: 0.615 ± 0.024	1.001TyrPro: 1.001 ± 0.033	0.722TyrGln: 0.722 ± 0.024	2.022TyrArg: 2.022 ± 0.043	1.219TyrSer: 1.219 ± 0.037	0.985TyrThr: 0.985 ± 0.03	1.679TyrVal: 1.679 ± 0.04	0.334TyrTrp: 0.334 ± 0.017	0.6TyrTyr: 0.6 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3667 proteins (1070970 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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