Amino acid dipepetide frequency for Wallemia ichthyophaga (strain EXF-994 / CBS 113033)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.728AlaAla: 6.728 ± 0.072	0.767AlaCys: 0.767 ± 0.018	3.914AlaAsp: 3.914 ± 0.037	4.123AlaGlu: 4.123 ± 0.045	2.952AlaPhe: 2.952 ± 0.048	4.514AlaGly: 4.514 ± 0.059	2.14AlaHis: 2.14 ± 0.036	4.248AlaIle: 4.248 ± 0.048	4.014AlaLys: 4.014 ± 0.052	7.375AlaLeu: 7.375 ± 0.064	1.59AlaMet: 1.59 ± 0.023	3.256AlaAsn: 3.256 ± 0.043	3.72AlaPro: 3.72 ± 0.056	3.626AlaGln: 3.626 ± 0.053	3.928AlaArg: 3.928 ± 0.049	6.351AlaSer: 6.351 ± 0.056	4.347AlaThr: 4.347 ± 0.047	4.582AlaVal: 4.582 ± 0.046	0.775AlaTrp: 0.775 ± 0.019	2.133AlaTyr: 2.133 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	0.778CysAla: 0.778 ± 0.02	0.191CysCys: 0.191 ± 0.01	0.614CysAsp: 0.614 ± 0.018	0.528CysGlu: 0.528 ± 0.015	0.445CysPhe: 0.445 ± 0.016	0.757CysGly: 0.757 ± 0.022	0.264CysHis: 0.264 ± 0.012	0.622CysIle: 0.622 ± 0.016	0.51CysLys: 0.51 ± 0.016	1.098CysLeu: 1.098 ± 0.023	0.219CysMet: 0.219 ± 0.01	0.437CysAsn: 0.437 ± 0.014	0.462CysPro: 0.462 ± 0.018	0.348CysGln: 0.348 ± 0.014	0.539CysArg: 0.539 ± 0.013	0.79CysSer: 0.79 ± 0.02	0.623CysThr: 0.623 ± 0.019	0.749CysVal: 0.749 ± 0.018	0.146CysTrp: 0.146 ± 0.007	0.325CysTyr: 0.325 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.724AspAla: 4.724 ± 0.049	0.57AspCys: 0.57 ± 0.019	5.165AspAsp: 5.165 ± 0.075	5.058AspGlu: 5.058 ± 0.059	2.196AspPhe: 2.196 ± 0.035	3.89AspGly: 3.89 ± 0.043	1.296AspHis: 1.296 ± 0.028	3.61AspIle: 3.61 ± 0.039	3.715AspLys: 3.715 ± 0.047	5.187AspLeu: 5.187 ± 0.047	1.324AspMet: 1.324 ± 0.024	2.924AspAsn: 2.924 ± 0.043	2.441AspPro: 2.441 ± 0.034	2.156AspGln: 2.156 ± 0.04	2.827AspArg: 2.827 ± 0.035	5.04AspSer: 5.04 ± 0.054	3.278AspThr: 3.278 ± 0.044	4.166AspVal: 4.166 ± 0.056	0.724AspTrp: 0.724 ± 0.018	1.837AspTyr: 1.837 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	4.401GluAla: 4.401 ± 0.049	0.693GluCys: 0.693 ± 0.019	4.301GluAsp: 4.301 ± 0.063	5.396GluGlu: 5.396 ± 0.078	1.909GluPhe: 1.909 ± 0.033	3.299GluGly: 3.299 ± 0.046	1.641GluHis: 1.641 ± 0.034	3.314GluIle: 3.314 ± 0.042	4.277GluLys: 4.277 ± 0.062	5.387GluLeu: 5.387 ± 0.05	1.617GluMet: 1.617 ± 0.024	2.974GluAsn: 2.974 ± 0.035	2.044GluPro: 2.044 ± 0.028	2.907GluGln: 2.907 ± 0.056	3.892GluArg: 3.892 ± 0.054	4.878GluSer: 4.878 ± 0.058	2.879GluThr: 2.879 ± 0.046	3.064GluVal: 3.064 ± 0.045	0.742GluTrp: 0.742 ± 0.019	1.854GluTyr: 1.854 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	2.656PheAla: 2.656 ± 0.041	0.437PheCys: 0.437 ± 0.016	2.663PheAsp: 2.663 ± 0.035	2.252PheGlu: 2.252 ± 0.033	1.408PhePhe: 1.408 ± 0.028	2.609PheGly: 2.609 ± 0.051	0.815PheHis: 0.815 ± 0.02	2.099PheIle: 2.099 ± 0.036	2.147PheLys: 2.147 ± 0.04	2.97PheLeu: 2.97 ± 0.043	0.685PheMet: 0.685 ± 0.017	2.091PheAsn: 2.091 ± 0.031	1.477PhePro: 1.477 ± 0.027	1.165PheGln: 1.165 ± 0.023	1.557PheArg: 1.557 ± 0.028	3.026PheSer: 3.026 ± 0.045	2.151PheThr: 2.151 ± 0.035	2.27PheVal: 2.27 ± 0.031	0.447PheTrp: 0.447 ± 0.013	1.126PheTyr: 1.126 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	4.263GlyAla: 4.263 ± 0.055	0.763GlyCys: 0.763 ± 0.022	3.562GlyAsp: 3.562 ± 0.049	3.604GlyGlu: 3.604 ± 0.046	2.358GlyPhe: 2.358 ± 0.037	4.979GlyGly: 4.979 ± 0.081	1.399GlyHis: 1.399 ± 0.031	3.119GlyIle: 3.119 ± 0.042	3.419GlyLys: 3.419 ± 0.047	5.294GlyLeu: 5.294 ± 0.05	1.424GlyMet: 1.424 ± 0.032	2.456GlyAsn: 2.456 ± 0.041	1.898GlyPro: 1.898 ± 0.032	2.11GlyGln: 2.11 ± 0.034	3.139GlyArg: 3.139 ± 0.04	4.93GlySer: 4.93 ± 0.058	3.017GlyThr: 3.017 ± 0.046	4.478GlyVal: 4.478 ± 0.045	0.851GlyTrp: 0.851 ± 0.02	1.868GlyTyr: 1.868 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	2.023HisAla: 2.023 ± 0.035	0.289HisCys: 0.289 ± 0.011	1.534HisAsp: 1.534 ± 0.031	1.329HisGlu: 1.329 ± 0.025	0.952HisPhe: 0.952 ± 0.022	1.365HisGly: 1.365 ± 0.033	0.96HisHis: 0.96 ± 0.031	1.44HisIle: 1.44 ± 0.027	1.459HisLys: 1.459 ± 0.029	2.722HisLeu: 2.722 ± 0.039	0.464HisMet: 0.464 ± 0.013	1.271HisAsn: 1.271 ± 0.025	1.768HisPro: 1.768 ± 0.037	1.16HisGln: 1.16 ± 0.025	1.357HisArg: 1.357 ± 0.026	2.906HisSer: 2.906 ± 0.047	1.91HisThr: 1.91 ± 0.042	1.503HisVal: 1.503 ± 0.027	0.27HisTrp: 0.27 ± 0.011	0.771HisTyr: 0.771 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	4.114IleAla: 4.114 ± 0.052	0.619IleCys: 0.619 ± 0.016	3.756IleAsp: 3.756 ± 0.042	3.385IleGlu: 3.385 ± 0.046	1.895IlePhe: 1.895 ± 0.032	3.198IleGly: 3.198 ± 0.042	1.47IleHis: 1.47 ± 0.024	2.769IleIle: 2.769 ± 0.041	3.111IleLys: 3.111 ± 0.04	4.724IleLeu: 4.724 ± 0.05	0.974IleMet: 0.974 ± 0.02	2.754IleAsn: 2.754 ± 0.035	3.148IlePro: 3.148 ± 0.041	2.172IleGln: 2.172 ± 0.034	2.722IleArg: 2.722 ± 0.041	4.583IleSer: 4.583 ± 0.047	2.948IleThr: 2.948 ± 0.036	3.093IleVal: 3.093 ± 0.047	0.589IleTrp: 0.589 ± 0.016	1.546IleTyr: 1.546 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	4.358LysAla: 4.358 ± 0.05	0.535LysCys: 0.535 ± 0.014	3.455LysAsp: 3.455 ± 0.046	4.105LysGlu: 4.105 ± 0.061	1.803LysPhe: 1.803 ± 0.029	3.005LysGly: 3.005 ± 0.036	1.638LysHis: 1.638 ± 0.031	2.719LysIle: 2.719 ± 0.039	4.305LysLys: 4.305 ± 0.066	5.34LysLeu: 5.34 ± 0.055	1.343LysMet: 1.343 ± 0.023	2.419LysAsn: 2.419 ± 0.038	3.056LysPro: 3.056 ± 0.043	2.915LysGln: 2.915 ± 0.05	3.807LysArg: 3.807 ± 0.053	5.103LysSer: 5.103 ± 0.054	3.023LysThr: 3.023 ± 0.034	3.235LysVal: 3.235 ± 0.052	0.605LysTrp: 0.605 ± 0.017	1.62LysTyr: 1.62 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	7.05LeuAla: 7.05 ± 0.061	1.066LeuCys: 1.066 ± 0.024	5.783LeuAsp: 5.783 ± 0.049	5.48LeuGlu: 5.48 ± 0.063	3.375LeuPhe: 3.375 ± 0.039	5.172LeuGly: 5.172 ± 0.056	2.478LeuHis: 2.478 ± 0.038	4.876LeuIle: 4.876 ± 0.053	5.246LeuLys: 5.246 ± 0.052	8.529LeuLeu: 8.529 ± 0.085	1.706LeuMet: 1.706 ± 0.027	4.786LeuAsn: 4.786 ± 0.052	4.914LeuPro: 4.914 ± 0.052	3.875LeuGln: 3.875 ± 0.043	5.096LeuArg: 5.096 ± 0.061	8.575LeuSer: 8.575 ± 0.068	4.968LeuThr: 4.968 ± 0.055	5.137LeuVal: 5.137 ± 0.06	0.902LeuTrp: 0.902 ± 0.021	2.428LeuTyr: 2.428 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	1.633MetAla: 1.633 ± 0.03	0.19MetCys: 0.19 ± 0.01	1.307MetAsp: 1.307 ± 0.025	1.248MetGlu: 1.248 ± 0.024	0.687MetPhe: 0.687 ± 0.016	1.24MetGly: 1.24 ± 0.027	0.547MetHis: 0.547 ± 0.017	1.037MetIle: 1.037 ± 0.022	1.143MetLys: 1.143 ± 0.023	1.805MetLeu: 1.805 ± 0.029	0.538MetMet: 0.538 ± 0.018	0.946MetAsn: 0.946 ± 0.021	1.02MetPro: 1.02 ± 0.023	0.936MetGln: 0.936 ± 0.02	1.259MetArg: 1.259 ± 0.022	2.206MetSer: 2.206 ± 0.032	1.159MetThr: 1.159 ± 0.021	1.079MetVal: 1.079 ± 0.023	0.185MetTrp: 0.185 ± 0.01	0.488MetTyr: 0.488 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.578AsnAla: 3.578 ± 0.042	0.43AsnCys: 0.43 ± 0.015	3.162AsnAsp: 3.162 ± 0.039	3.006AsnGlu: 3.006 ± 0.039	1.518AsnPhe: 1.518 ± 0.027	2.799AsnGly: 2.799 ± 0.04	1.302AsnHis: 1.302 ± 0.025	2.586AsnIle: 2.586 ± 0.033	2.973AsnLys: 2.973 ± 0.042	4.166AsnLeu: 4.166 ± 0.043	0.948AsnMet: 0.948 ± 0.023	2.626AsnAsn: 2.626 ± 0.046	2.477AsnPro: 2.477 ± 0.035	2.102AsnGln: 2.102 ± 0.026	2.158AsnArg: 2.158 ± 0.03	4.165AsnSer: 4.165 ± 0.043	3.189AsnThr: 3.189 ± 0.045	2.896AsnVal: 2.896 ± 0.037	0.557AsnTrp: 0.557 ± 0.019	1.396AsnTyr: 1.396 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	3.855ProAla: 3.855 ± 0.053	0.323ProCys: 0.323 ± 0.013	2.465ProAsp: 2.465 ± 0.033	2.733ProGlu: 2.733 ± 0.041	1.891ProPhe: 1.891 ± 0.032	2.441ProGly: 2.441 ± 0.039	1.559ProHis: 1.559 ± 0.032	2.683ProIle: 2.683 ± 0.04	2.596ProLys: 2.596 ± 0.037	4.392ProLeu: 4.392 ± 0.046	0.833ProMet: 0.833 ± 0.02	2.34ProAsn: 2.34 ± 0.031	4.552ProPro: 4.552 ± 0.095	2.682ProGln: 2.682 ± 0.045	2.409ProArg: 2.409 ± 0.039	5.675ProSer: 5.675 ± 0.069	3.641ProThr: 3.641 ± 0.043	2.751ProVal: 2.751 ± 0.045	0.452ProTrp: 0.452 ± 0.014	1.403ProTyr: 1.403 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	3.227GlnAla: 3.227 ± 0.047	0.377GlnCys: 0.377 ± 0.014	2.381GlnAsp: 2.381 ± 0.038	2.322GlnGlu: 2.322 ± 0.043	1.506GlnPhe: 1.506 ± 0.026	2.121GlnGly: 2.121 ± 0.032	1.408GlnHis: 1.408 ± 0.032	2.22GlnIle: 2.22 ± 0.031	2.238GlnLys: 2.238 ± 0.038	4.52GlnLeu: 4.52 ± 0.054	0.968GlnMet: 0.968 ± 0.022	1.836GlnAsn: 1.836 ± 0.031	2.998GlnPro: 2.998 ± 0.055	3.423GlnGln: 3.423 ± 0.093	2.654GlnArg: 2.654 ± 0.036	4.394GlnSer: 4.394 ± 0.055	2.418GlnThr: 2.418 ± 0.034	2.548GlnVal: 2.548 ± 0.035	0.436GlnTrp: 0.436 ± 0.013	1.132GlnTyr: 1.132 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	3.692ArgAla: 3.692 ± 0.045	0.623ArgCys: 0.623 ± 0.02	3.097ArgAsp: 3.097 ± 0.043	3.424ArgGlu: 3.424 ± 0.054	1.906ArgPhe: 1.906 ± 0.029	3.06ArgGly: 3.06 ± 0.041	1.366ArgHis: 1.366 ± 0.025	2.826ArgIle: 2.826 ± 0.035	3.538ArgLys: 3.538 ± 0.051	4.982ArgLeu: 4.982 ± 0.051	1.247ArgMet: 1.247 ± 0.021	2.45ArgAsn: 2.45 ± 0.036	2.359ArgPro: 2.359 ± 0.039	2.522ArgGln: 2.522 ± 0.037	4.117ArgArg: 4.117 ± 0.064	4.665ArgSer: 4.665 ± 0.057	2.655ArgThr: 2.655 ± 0.037	3.242ArgVal: 3.242 ± 0.038	0.637ArgTrp: 0.637 ± 0.017	1.594ArgTyr: 1.594 ± 0.027	0.0ArgXaa: 0.0 ± 0.0
Ser	6.383SerAla: 6.383 ± 0.064	0.758SerCys: 0.758 ± 0.018	5.101SerAsp: 5.101 ± 0.058	4.56SerGlu: 4.56 ± 0.049	3.311SerPhe: 3.311 ± 0.035	5.146SerGly: 5.146 ± 0.057	2.59SerHis: 2.59 ± 0.044	5.008SerIle: 5.008 ± 0.052	5.035SerLys: 5.035 ± 0.054	8.118SerLeu: 8.118 ± 0.075	1.627SerMet: 1.627 ± 0.028	4.924SerAsn: 4.924 ± 0.056	4.763SerPro: 4.763 ± 0.064	4.105SerGln: 4.105 ± 0.06	4.54SerArg: 4.54 ± 0.062	9.436SerSer: 9.436 ± 0.136	6.318SerThr: 6.318 ± 0.06	4.945SerVal: 4.945 ± 0.052	0.854SerTrp: 0.854 ± 0.024	2.309SerTyr: 2.309 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	4.242ThrAla: 4.242 ± 0.044	0.589ThrCys: 0.589 ± 0.016	2.818ThrAsp: 2.818 ± 0.037	2.696ThrGlu: 2.696 ± 0.038	2.12ThrPhe: 2.12 ± 0.03	3.199ThrGly: 3.199 ± 0.04	2.037ThrHis: 2.037 ± 0.037	3.062ThrIle: 3.062 ± 0.037	2.894ThrLys: 2.894 ± 0.036	5.785ThrLeu: 5.785 ± 0.055	0.962ThrMet: 0.962 ± 0.021	2.746ThrAsn: 2.746 ± 0.038	4.304ThrPro: 4.304 ± 0.057	2.946ThrGln: 2.946 ± 0.044	2.907ThrArg: 2.907 ± 0.037	5.313ThrSer: 5.313 ± 0.058	3.678ThrThr: 3.678 ± 0.045	3.066ThrVal: 3.066 ± 0.037	0.544ThrTrp: 0.544 ± 0.016	1.541ThrTyr: 1.541 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	4.498ValAla: 4.498 ± 0.043	0.721ValCys: 0.721 ± 0.02	4.481ValAsp: 4.481 ± 0.056	4.033ValGlu: 4.033 ± 0.071	2.266ValPhe: 2.266 ± 0.034	3.808ValGly: 3.808 ± 0.05	1.555ValHis: 1.555 ± 0.027	3.134ValIle: 3.134 ± 0.045	3.489ValLys: 3.489 ± 0.049	5.243ValLeu: 5.243 ± 0.061	1.285ValMet: 1.285 ± 0.026	2.746ValAsn: 2.746 ± 0.036	2.601ValPro: 2.601 ± 0.038	2.411ValGln: 2.411 ± 0.034	2.982ValArg: 2.982 ± 0.038	4.487ValSer: 4.487 ± 0.05	2.804ValThr: 2.804 ± 0.033	4.035ValVal: 4.035 ± 0.05	0.672ValTrp: 0.672 ± 0.017	1.772ValTyr: 1.772 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	0.671TrpAla: 0.671 ± 0.017	0.169TrpCys: 0.169 ± 0.009	0.694TrpAsp: 0.694 ± 0.017	0.594TrpGlu: 0.594 ± 0.016	0.445TrpPhe: 0.445 ± 0.015	0.617TrpGly: 0.617 ± 0.017	0.266TrpHis: 0.266 ± 0.011	0.634TrpIle: 0.634 ± 0.018	0.664TrpLys: 0.664 ± 0.017	1.085TrpLeu: 1.085 ± 0.026	0.298TrpMet: 0.298 ± 0.011	0.569TrpAsn: 0.569 ± 0.016	0.389TrpPro: 0.389 ± 0.014	0.436TrpGln: 0.436 ± 0.013	0.667TrpArg: 0.667 ± 0.021	1.0TrpSer: 1.0 ± 0.021	0.617TrpThr: 0.617 ± 0.017	0.594TrpVal: 0.594 ± 0.018	0.179TrpTrp: 0.179 ± 0.01	0.32TrpTyr: 0.32 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.209TyrAla: 2.209 ± 0.035	0.333TyrCys: 0.333 ± 0.013	1.87TyrAsp: 1.87 ± 0.031	1.593TyrGlu: 1.593 ± 0.031	1.109TyrPhe: 1.109 ± 0.023	1.714TyrGly: 1.714 ± 0.034	0.722TyrHis: 0.722 ± 0.02	1.565TyrIle: 1.565 ± 0.028	1.62TyrLys: 1.62 ± 0.028	2.722TyrLeu: 2.722 ± 0.035	0.6TyrMet: 0.6 ± 0.017	1.488TyrAsn: 1.488 ± 0.025	1.282TyrPro: 1.282 ± 0.024	1.13TyrGln: 1.13 ± 0.023	1.444TyrArg: 1.444 ± 0.027	2.304TyrSer: 2.304 ± 0.035	1.825TyrThr: 1.825 ± 0.027	1.59TyrVal: 1.59 ± 0.028	0.343TyrTrp: 0.343 ± 0.012	0.884TyrTyr: 0.884 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4836 proteins (2342023 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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