Human papillomavirus 24

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Betapapillomavirus; Betapapillomavirus 1

Average proteome isoelectric point is 5.78

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P50790|VL1_HPV24 Major capsid protein L1 OS=Human papillomavirus 24 OX=37956 GN=L1 PE=3 SV=1
MM1 pKa = 7.37IGKK4 pKa = 8.93EE5 pKa = 3.9VTLQDD10 pKa = 3.06IVLEE14 pKa = 4.09LTEE17 pKa = 4.4PQTVDD22 pKa = 2.9LHH24 pKa = 8.11CEE26 pKa = 4.01EE27 pKa = 5.16EE28 pKa = 4.64LPEE31 pKa = 4.02QDD33 pKa = 3.61TEE35 pKa = 4.39VEE37 pKa = 4.2PEE39 pKa = 3.43RR40 pKa = 11.84RR41 pKa = 11.84AYY43 pKa = 9.56KK44 pKa = 10.26IILCCGGGCGTRR56 pKa = 11.84LRR58 pKa = 11.84LFVAATQFGIRR69 pKa = 11.84GLQDD73 pKa = 3.58LLLEE77 pKa = 4.39EE78 pKa = 4.93VVILCPDD85 pKa = 3.54CRR87 pKa = 11.84NSDD90 pKa = 3.89LQHH93 pKa = 6.61GGQQ96 pKa = 3.6

Molecular weight: 10.71 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P50777|VE6_HPV24 Protein E6 OS=Human papillomavirus 24 OX=37956 GN=E6 PE=3 SV=1
MM1 pKa = 7.68EE2 pKa = 4.75NLKK5 pKa = 10.64KK6 pKa = 10.63RR7 pKa = 11.84FDD9 pKa = 3.8VLQDD13 pKa = 3.53LLMNIYY19 pKa = 9.79EE20 pKa = 4.28QGSDD24 pKa = 3.13TLEE27 pKa = 3.98SQIEE31 pKa = 3.96HH32 pKa = 5.42WQALRR37 pKa = 11.84RR38 pKa = 11.84EE39 pKa = 4.31AVLLYY44 pKa = 9.22YY45 pKa = 10.62ARR47 pKa = 11.84QNGVLRR53 pKa = 11.84LGYY56 pKa = 10.65LPVPPLATSEE66 pKa = 4.54AKK68 pKa = 10.21AKK70 pKa = 10.05QAISMVLQLQSLQQSPYY87 pKa = 9.25GTEE90 pKa = 3.14KK91 pKa = 8.53WTLVDD96 pKa = 3.44TSIEE100 pKa = 4.32TFKK103 pKa = 10.35NTPEE107 pKa = 3.73NHH109 pKa = 6.18FKK111 pKa = 10.72KK112 pKa = 10.82GPINVEE118 pKa = 3.94VIYY121 pKa = 11.13DD122 pKa = 4.16GDD124 pKa = 4.07PDD126 pKa = 3.81NANLYY131 pKa = 8.07TMWKK135 pKa = 7.96YY136 pKa = 11.05VYY138 pKa = 11.28YY139 pKa = 10.15MDD141 pKa = 6.88DD142 pKa = 3.2NDD144 pKa = 3.31QWQKK148 pKa = 9.6TEE150 pKa = 3.72SGANHH155 pKa = 6.05TGIYY159 pKa = 9.67YY160 pKa = 10.58LIGEE164 pKa = 4.75FKK166 pKa = 10.36HH167 pKa = 6.48YY168 pKa = 10.62YY169 pKa = 10.29VLFADD174 pKa = 4.16DD175 pKa = 3.92ANRR178 pKa = 11.84YY179 pKa = 8.46SKK181 pKa = 10.61SGQWEE186 pKa = 3.78VRR188 pKa = 11.84INKK191 pKa = 7.16EE192 pKa = 4.11TVFAPVTSSTPPDD205 pKa = 3.48SPGGSRR211 pKa = 11.84EE212 pKa = 4.24LPGSTANSKK221 pKa = 10.66ASSPTQQPQQACSDD235 pKa = 3.65EE236 pKa = 4.2TTKK239 pKa = 10.62RR240 pKa = 11.84KK241 pKa = 9.97RR242 pKa = 11.84YY243 pKa = 8.9GRR245 pKa = 11.84RR246 pKa = 11.84EE247 pKa = 3.88SSPTDD252 pKa = 3.09SRR254 pKa = 11.84CRR256 pKa = 11.84RR257 pKa = 11.84RR258 pKa = 11.84SSSRR262 pKa = 11.84QKK264 pKa = 10.04KK265 pKa = 7.31QGRR268 pKa = 11.84RR269 pKa = 11.84ARR271 pKa = 11.84SRR273 pKa = 11.84TRR275 pKa = 11.84SRR277 pKa = 11.84CSSTQTRR284 pKa = 11.84SRR286 pKa = 11.84STSRR290 pKa = 11.84RR291 pKa = 11.84SRR293 pKa = 11.84STSRR297 pKa = 11.84GNRR300 pKa = 11.84RR301 pKa = 11.84CRR303 pKa = 11.84GDD305 pKa = 3.24TPRR308 pKa = 11.84GQRR311 pKa = 11.84GVSTSSRR318 pKa = 11.84GRR320 pKa = 11.84GRR322 pKa = 11.84GSRR325 pKa = 11.84RR326 pKa = 11.84SSSSSSPTPRR336 pKa = 11.84TKK338 pKa = 10.67ASQRR342 pKa = 11.84GCDD345 pKa = 3.33TRR347 pKa = 11.84SVRR350 pKa = 11.84DD351 pKa = 3.59SGISPGDD358 pKa = 3.42VGRR361 pKa = 11.84KK362 pKa = 8.3LQTVSGRR369 pKa = 11.84NSGRR373 pKa = 11.84LGRR376 pKa = 11.84LLEE379 pKa = 4.34EE380 pKa = 4.6ALDD383 pKa = 3.9PPVILLRR390 pKa = 11.84GGANTLKK397 pKa = 10.56CFRR400 pKa = 11.84NRR402 pKa = 11.84AKK404 pKa = 10.47LRR406 pKa = 11.84YY407 pKa = 8.28RR408 pKa = 11.84GHH410 pKa = 6.07YY411 pKa = 9.54KK412 pKa = 10.53AFSTSWSWVAADD424 pKa = 3.35GTEE427 pKa = 3.74RR428 pKa = 11.84LGRR431 pKa = 11.84SRR433 pKa = 11.84LLVSFTSFKK442 pKa = 10.4QRR444 pKa = 11.84SGFLDD449 pKa = 3.59LVRR452 pKa = 11.84FPKK455 pKa = 10.67GVDD458 pKa = 2.85WSLGSFDD465 pKa = 4.85KK466 pKa = 11.38LL467 pKa = 3.56

Molecular weight: 52.86 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2568

96

607

366.9

41.17

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.607 ± 0.384

2.064 ± 0.659

5.919 ± 0.237

6.659 ± 0.723

3.933 ± 0.628

6.737 ± 1.044

1.908 ± 0.272

4.4 ± 0.566

4.673 ± 0.779

9.034 ± 0.777

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.363 ± 0.383

4.361 ± 0.646

6.62 ± 1.79

5.023 ± 0.191

6.737 ± 1.35

8.255 ± 1.031

6.347 ± 0.642

5.841 ± 0.673

1.285 ± 0.378

3.232 ± 0.431
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski