Human papillomavirus type 156

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 18

Average proteome isoelectric point is 6.24

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|K7QNV2|K7QNV2_9PAPI Major capsid protein L1 OS=Human papillomavirus type 156 OX=1248396 GN=L1 PE=3 SV=1
MM1 pKa = 7.48IGNRR5 pKa = 11.84PDD7 pKa = 3.15IKK9 pKa = 10.88DD10 pKa = 3.32IEE12 pKa = 5.23LDD14 pKa = 3.37LHH16 pKa = 7.05ALVLPANLLSEE27 pKa = 4.67EE28 pKa = 4.24SLSPDD33 pKa = 3.08SEE35 pKa = 4.39AEE37 pKa = 3.99EE38 pKa = 4.52EE39 pKa = 4.71EE40 pKa = 4.05EE41 pKa = 4.0HH42 pKa = 6.65SPYY45 pKa = 10.65RR46 pKa = 11.84VDD48 pKa = 3.57TCCKK52 pKa = 9.36SCGTGVRR59 pKa = 11.84LCVFATQLAIRR70 pKa = 11.84TLQQLLTQEE79 pKa = 4.66LSLVCPGCSRR89 pKa = 11.84NLFHH93 pKa = 7.8HH94 pKa = 6.52GRR96 pKa = 11.84LL97 pKa = 3.68

Molecular weight: 10.78 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|K7QR99|K7QR99_9PAPI Protein E6 OS=Human papillomavirus type 156 OX=1248396 GN=E6 PE=3 SV=1
MM1 pKa = 7.02NQADD5 pKa = 3.85LTVRR9 pKa = 11.84FDD11 pKa = 3.76ALQEE15 pKa = 4.01RR16 pKa = 11.84LMTLYY21 pKa = 10.92EE22 pKa = 4.27EE23 pKa = 4.61GRR25 pKa = 11.84KK26 pKa = 8.15TIDD29 pKa = 3.05AQIEE33 pKa = 4.05YY34 pKa = 8.63WQLIRR39 pKa = 11.84KK40 pKa = 8.64EE41 pKa = 4.36SVLMYY46 pKa = 9.58YY47 pKa = 10.26GRR49 pKa = 11.84KK50 pKa = 9.56EE51 pKa = 3.82GFKK54 pKa = 11.0NFGLQPLPALTVSEE68 pKa = 4.61YY69 pKa = 10.14KK70 pKa = 10.62AKK72 pKa = 10.22EE73 pKa = 4.1AIRR76 pKa = 11.84QVLLLKK82 pKa = 10.3SLKK85 pKa = 10.62NSVFGNEE92 pKa = 3.86EE93 pKa = 3.42WTLPEE98 pKa = 3.82TSAEE102 pKa = 4.14LTYY105 pKa = 9.67TAPRR109 pKa = 11.84NTFKK113 pKa = 10.88KK114 pKa = 10.38DD115 pKa = 3.05PYY117 pKa = 10.42TVDD120 pKa = 2.01VWFDD124 pKa = 3.8HH125 pKa = 6.84NPDD128 pKa = 3.01NSFPYY133 pKa = 10.03TNWNKK138 pKa = 9.97IYY140 pKa = 10.35FQGDD144 pKa = 2.95HH145 pKa = 7.21DD146 pKa = 4.0NWHH149 pKa = 6.32RR150 pKa = 11.84AAGKK154 pKa = 10.14VDD156 pKa = 3.24INGLYY161 pKa = 10.5FEE163 pKa = 5.55DD164 pKa = 4.09ANGDD168 pKa = 2.96KK169 pKa = 10.97SYY171 pKa = 11.0FVVFASDD178 pKa = 3.11AQRR181 pKa = 11.84YY182 pKa = 5.84GTTGEE187 pKa = 4.01WTVHH191 pKa = 5.35YY192 pKa = 10.09KK193 pKa = 10.71NEE195 pKa = 4.7TISSTSLSSQRR206 pKa = 11.84SLSTISSQGSVSSSRR221 pKa = 11.84DD222 pKa = 3.31SIPAKK227 pKa = 10.05KK228 pKa = 9.88GQSTRR233 pKa = 11.84RR234 pKa = 11.84HH235 pKa = 4.56QSEE238 pKa = 4.07EE239 pKa = 4.32GIADD243 pKa = 3.7SSSSSTSSSPSAVRR257 pKa = 11.84RR258 pKa = 11.84GRR260 pKa = 11.84RR261 pKa = 11.84RR262 pKa = 11.84PQQGEE267 pKa = 3.94HH268 pKa = 5.46TSRR271 pKa = 11.84GGGTRR276 pKa = 11.84AKK278 pKa = 9.93RR279 pKa = 11.84QRR281 pKa = 11.84TEE283 pKa = 3.98EE284 pKa = 4.03VSTTVSPDD292 pKa = 2.85EE293 pKa = 4.15VGRR296 pKa = 11.84GNTSVPRR303 pKa = 11.84TNLTRR308 pKa = 11.84LEE310 pKa = 4.12RR311 pKa = 11.84LAKK314 pKa = 9.69EE315 pKa = 4.22ARR317 pKa = 11.84DD318 pKa = 3.72PPIVLIKK325 pKa = 10.68GRR327 pKa = 11.84SNPLKK332 pKa = 9.17CWRR335 pKa = 11.84YY336 pKa = 9.56RR337 pKa = 11.84CEE339 pKa = 4.1KK340 pKa = 10.72HH341 pKa = 6.68CDD343 pKa = 3.11LYY345 pKa = 11.68DD346 pKa = 4.97RR347 pKa = 11.84ISTVFKK353 pKa = 10.02WVNSTNDD360 pKa = 3.46CNMHH364 pKa = 6.72RR365 pKa = 11.84LLISFKK371 pKa = 10.42NQNQRR376 pKa = 11.84SMFLKK381 pKa = 10.44FVNLPKK387 pKa = 10.88GCTFSLGSLDD397 pKa = 4.62SII399 pKa = 5.04

Molecular weight: 45.54 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2505

97

608

357.9

40.71

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.511 ± 0.515

2.555 ± 0.861

6.667 ± 0.42

6.228 ± 0.41

5.03 ± 0.452

5.19 ± 0.609

1.916 ± 0.272

5.469 ± 0.715

5.629 ± 0.923

9.261 ± 0.975

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.756 ± 0.338

5.07 ± 0.405

5.988 ± 1.149

4.271 ± 0.428

5.788 ± 0.626

7.824 ± 1.019

5.948 ± 0.57

6.267 ± 0.61

1.158 ± 0.413

3.473 ± 0.552
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski