Amino acid dipepetide frequency for Tomato leaf curl Mayotte virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.014AlaAla: 6.014 ± 2.137
1.718AlaCys: 1.718 ± 0.705
1.718AlaAsp: 1.718 ± 1.01
0.0AlaGlu: 0.0 ± 0.0
0.0AlaPhe: 0.0 ± 0.0
0.0AlaGly: 0.0 ± 0.0
0.859AlaHis: 0.859 ± 0.903
2.577AlaIle: 2.577 ± 2.035
4.296AlaLys: 4.296 ± 0.999
4.296AlaLeu: 4.296 ± 1.24
0.859AlaMet: 0.859 ± 0.593
1.718AlaAsn: 1.718 ± 1.293
6.873AlaPro: 6.873 ± 1.727
4.296AlaGln: 4.296 ± 1.871
5.155AlaArg: 5.155 ± 2.096
2.577AlaSer: 2.577 ± 1.442
4.296AlaThr: 4.296 ± 1.856
4.296AlaVal: 4.296 ± 1.002
0.859AlaTrp: 0.859 ± 0.647
0.859AlaTyr: 0.859 ± 0.647
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.718CysCys: 1.718 ± 1.805
0.0CysAsp: 0.0 ± 0.0
1.718CysGlu: 1.718 ± 0.705
0.859CysPhe: 0.859 ± 0.977
1.718CysGly: 1.718 ± 0.984
0.0CysHis: 0.0 ± 0.0
0.859CysIle: 0.859 ± 1.006
1.718CysLys: 1.718 ± 0.705
0.859CysLeu: 0.859 ± 0.915
0.859CysMet: 0.859 ± 0.903
0.859CysAsn: 0.859 ± 0.647
2.577CysPro: 2.577 ± 2.057
0.0CysGln: 0.0 ± 0.0
0.859CysArg: 0.859 ± 0.647
2.577CysSer: 2.577 ± 2.186
2.577CysThr: 2.577 ± 0.901
2.577CysVal: 2.577 ± 1.55
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.577AspAla: 2.577 ± 1.94
1.718AspCys: 1.718 ± 1.34
1.718AspAsp: 1.718 ± 0.705
2.577AspGlu: 2.577 ± 0.901
1.718AspPhe: 1.718 ± 0.705
1.718AspGly: 1.718 ± 1.293
2.577AspHis: 2.577 ± 2.121
1.718AspIle: 1.718 ± 1.141
0.859AspLys: 0.859 ± 0.647
5.155AspLeu: 5.155 ± 0.96
0.0AspMet: 0.0 ± 0.0
0.859AspAsn: 0.859 ± 0.662
1.718AspPro: 1.718 ± 0.909
0.0AspGln: 0.0 ± 0.0
3.436AspArg: 3.436 ± 1.335
5.155AspSer: 5.155 ± 1.328
2.577AspThr: 2.577 ± 1.882
6.014AspVal: 6.014 ± 2.144
2.577AspTrp: 2.577 ± 1.327
0.859AspTyr: 0.859 ± 0.903
0.0AspXaa: 0.0 ± 0.0
Glu
3.436GluAla: 3.436 ± 1.145
0.0GluCys: 0.0 ± 0.0
0.859GluAsp: 0.859 ± 0.915
6.014GluGlu: 6.014 ± 2.779
4.296GluPhe: 4.296 ± 1.709
6.014GluGly: 6.014 ± 1.182
0.0GluHis: 0.0 ± 0.0
1.718GluIle: 1.718 ± 1.955
2.577GluLys: 2.577 ± 1.32
7.732GluLeu: 7.732 ± 2.356
0.0GluMet: 0.0 ± 0.0
4.296GluAsn: 4.296 ± 1.722
5.155GluPro: 5.155 ± 1.401
2.577GluGln: 2.577 ± 1.55
0.0GluArg: 0.0 ± 0.0
0.859GluSer: 0.859 ± 0.915
2.577GluThr: 2.577 ± 1.159
0.0GluVal: 0.0 ± 0.0
2.577GluTrp: 2.577 ± 1.327
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.859PheCys: 0.859 ± 0.662
2.577PheAsp: 2.577 ± 1.205
0.859PheGlu: 0.859 ± 0.647
1.718PhePhe: 1.718 ± 1.324
0.859PheGly: 0.859 ± 0.662
3.436PheHis: 3.436 ± 1.145
3.436PheIle: 3.436 ± 1.841
2.577PheLys: 2.577 ± 1.084
7.732PheLeu: 7.732 ± 1.717
0.859PheMet: 0.859 ± 0.647
4.296PheAsn: 4.296 ± 2.737
1.718PhePro: 1.718 ± 1.311
3.436PheGln: 3.436 ± 1.841
5.155PheArg: 5.155 ± 2.598
1.718PheSer: 1.718 ± 2.012
0.859PheThr: 0.859 ± 1.006
0.859PheVal: 0.859 ± 0.647
0.0PheTrp: 0.0 ± 0.0
0.859PheTyr: 0.859 ± 0.662
0.0PheXaa: 0.0 ± 0.0
Gly
2.577GlyAla: 2.577 ± 1.179
1.718GlyCys: 1.718 ± 1.103
3.436GlyAsp: 3.436 ± 1.967
4.296GlyGlu: 4.296 ± 1.769
1.718GlyPhe: 1.718 ± 1.327
2.577GlyGly: 2.577 ± 1.179
1.718GlyHis: 1.718 ± 0.909
4.296GlyIle: 4.296 ± 1.302
5.155GlyLys: 5.155 ± 1.587
1.718GlyLeu: 1.718 ± 1.341
0.859GlyMet: 0.859 ± 0.662
2.577GlyAsn: 2.577 ± 1.809
3.436GlyPro: 3.436 ± 1.409
2.577GlyGln: 2.577 ± 0.831
0.859GlyArg: 0.859 ± 0.647
3.436GlySer: 3.436 ± 1.145
2.577GlyThr: 2.577 ± 2.004
1.718GlyVal: 1.718 ± 1.955
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
3.436HisAla: 3.436 ± 1.697
2.577HisCys: 2.577 ± 2.176
0.859HisAsp: 0.859 ± 0.977
1.718HisGlu: 1.718 ± 0.909
3.436HisPhe: 3.436 ± 1.343
1.718HisGly: 1.718 ± 1.327
2.577HisHis: 2.577 ± 3.018
2.577HisIle: 2.577 ± 1.882
1.718HisLys: 1.718 ± 1.288
0.859HisLeu: 0.859 ± 0.647
0.859HisMet: 0.859 ± 0.647
3.436HisAsn: 3.436 ± 1.265
1.718HisPro: 1.718 ± 0.965
1.718HisGln: 1.718 ± 0.705
3.436HisArg: 3.436 ± 2.974
0.0HisSer: 0.0 ± 0.0
2.577HisThr: 2.577 ± 1.986
3.436HisVal: 3.436 ± 2.142
0.0HisTrp: 0.0 ± 0.0
0.859HisTyr: 0.859 ± 0.647
0.0HisXaa: 0.0 ± 0.0
Ile
0.859IleAla: 0.859 ± 0.915
1.718IleCys: 1.718 ± 0.909
4.296IleAsp: 4.296 ± 1.687
1.718IleGlu: 1.718 ± 0.909
2.577IlePhe: 2.577 ± 1.94
0.0IleGly: 0.0 ± 0.0
3.436IleHis: 3.436 ± 1.227
3.436IleIle: 3.436 ± 2.282
6.014IleLys: 6.014 ± 1.104
0.859IleLeu: 0.859 ± 0.662
0.859IleMet: 0.859 ± 0.948
3.436IleAsn: 3.436 ± 1.032
0.859IlePro: 0.859 ± 0.647
6.873IleGln: 6.873 ± 2.578
5.155IleArg: 5.155 ± 1.792
6.873IleSer: 6.873 ± 1.455
3.436IleThr: 3.436 ± 1.17
3.436IleVal: 3.436 ± 1.335
1.718IleTrp: 1.718 ± 1.141
2.577IleTyr: 2.577 ± 1.589
0.0IleXaa: 0.0 ± 0.0
Lys
1.718LysAla: 1.718 ± 1.327
0.859LysCys: 0.859 ± 0.977
1.718LysAsp: 1.718 ± 1.293
6.014LysGlu: 6.014 ± 2.782
4.296LysPhe: 4.296 ± 0.986
3.436LysGly: 3.436 ± 0.976
2.577LysHis: 2.577 ± 0.831
5.155LysIle: 5.155 ± 1.916
4.296LysLys: 4.296 ± 1.767
0.0LysLeu: 0.0 ± 0.0
0.0LysMet: 0.0 ± 0.0
3.436LysAsn: 3.436 ± 1.767
2.577LysPro: 2.577 ± 0.907
1.718LysGln: 1.718 ± 1.082
4.296LysArg: 4.296 ± 1.722
6.014LysSer: 6.014 ± 1.708
3.436LysThr: 3.436 ± 1.759
3.436LysVal: 3.436 ± 1.238
0.0LysTrp: 0.0 ± 0.0
4.296LysTyr: 4.296 ± 1.831
0.0LysXaa: 0.0 ± 0.0
Leu
2.577LeuAla: 2.577 ± 1.145
1.718LeuCys: 1.718 ± 1.293
5.155LeuAsp: 5.155 ± 2.08
3.436LeuGlu: 3.436 ± 1.343
2.577LeuPhe: 2.577 ± 1.084
5.155LeuGly: 5.155 ± 1.808
3.436LeuHis: 3.436 ± 1.289
3.436LeuIle: 3.436 ± 2.182
3.436LeuLys: 3.436 ± 1.032
4.296LeuLeu: 4.296 ± 2.206
0.0LeuMet: 0.0 ± 0.0
6.014LeuAsn: 6.014 ± 1.481
1.718LeuPro: 1.718 ± 0.984
4.296LeuGln: 4.296 ± 1.978
6.873LeuArg: 6.873 ± 1.582
6.014LeuSer: 6.014 ± 3.149
4.296LeuThr: 4.296 ± 2.621
3.436LeuVal: 3.436 ± 1.409
0.0LeuTrp: 0.0 ± 0.0
4.296LeuTyr: 4.296 ± 1.831
0.0LeuXaa: 0.0 ± 0.0
Met
0.859MetAla: 0.859 ± 0.662
0.0MetCys: 0.0 ± 0.0
4.296MetAsp: 4.296 ± 1.384
0.859MetGlu: 0.859 ± 0.915
3.436MetPhe: 3.436 ± 1.238
1.718MetGly: 1.718 ± 0.931
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.859MetLys: 0.859 ± 0.662
0.859MetLeu: 0.859 ± 0.903
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.718MetPro: 1.718 ± 0.965
0.859MetGln: 0.859 ± 0.915
0.859MetArg: 0.859 ± 1.006
0.859MetSer: 0.859 ± 0.662
0.859MetThr: 0.859 ± 0.915
0.0MetVal: 0.0 ± 0.0
1.718MetTrp: 1.718 ± 0.909
2.577MetTyr: 2.577 ± 1.205
0.0MetXaa: 0.0 ± 0.0
Asn
4.296AsnAla: 4.296 ± 1.594
1.718AsnCys: 1.718 ± 0.984
2.577AsnAsp: 2.577 ± 1.179
1.718AsnGlu: 1.718 ± 1.082
2.577AsnPhe: 2.577 ± 1.297
0.859AsnGly: 0.859 ± 0.647
4.296AsnHis: 4.296 ± 2.254
3.436AsnIle: 3.436 ± 1.17
0.0AsnLys: 0.0 ± 0.0
4.296AsnLeu: 4.296 ± 1.691
4.296AsnMet: 4.296 ± 1.188
0.0AsnAsn: 0.0 ± 0.0
4.296AsnPro: 4.296 ± 0.986
2.577AsnGln: 2.577 ± 1.179
1.718AsnArg: 1.718 ± 0.965
5.155AsnSer: 5.155 ± 2.431
2.577AsnThr: 2.577 ± 1.294
2.577AsnVal: 2.577 ± 1.294
0.0AsnTrp: 0.0 ± 0.0
0.859AsnTyr: 0.859 ± 0.647
0.0AsnXaa: 0.0 ± 0.0
Pro
5.155ProAla: 5.155 ± 1.051
1.718ProCys: 1.718 ± 1.082
2.577ProAsp: 2.577 ± 1.372
2.577ProGlu: 2.577 ± 1.327
1.718ProPhe: 1.718 ± 0.965
2.577ProGly: 2.577 ± 0.831
4.296ProHis: 4.296 ± 1.695
3.436ProIle: 3.436 ± 1.116
5.155ProLys: 5.155 ± 2.172
5.155ProLeu: 5.155 ± 1.997
2.577ProMet: 2.577 ± 1.642
1.718ProAsn: 1.718 ± 0.909
0.859ProPro: 0.859 ± 0.647
4.296ProGln: 4.296 ± 1.836
3.436ProArg: 3.436 ± 2.15
6.873ProSer: 6.873 ± 2.512
4.296ProThr: 4.296 ± 2.186
1.718ProVal: 1.718 ± 1.103
0.859ProTrp: 0.859 ± 0.647
2.577ProTyr: 2.577 ± 1.205
0.0ProXaa: 0.0 ± 0.0
Gln
4.296GlnAla: 4.296 ± 2.166
0.859GlnCys: 0.859 ± 0.647
1.718GlnAsp: 1.718 ± 1.327
2.577GlnGlu: 2.577 ± 1.179
1.718GlnPhe: 1.718 ± 1.293
2.577GlnGly: 2.577 ± 1.168
1.718GlnHis: 1.718 ± 2.012
6.014GlnIle: 6.014 ± 2.808
3.436GlnLys: 3.436 ± 2.182
2.577GlnLeu: 2.577 ± 2.186
0.859GlnMet: 0.859 ± 1.006
4.296GlnAsn: 4.296 ± 1.086
5.155GlnPro: 5.155 ± 3.234
0.859GlnGln: 0.859 ± 0.647
2.577GlnArg: 2.577 ± 0.831
4.296GlnSer: 4.296 ± 1.63
3.436GlnThr: 3.436 ± 2.182
5.155GlnVal: 5.155 ± 2.381
0.0GlnTrp: 0.0 ± 0.0
0.859GlnTyr: 0.859 ± 0.915
0.0GlnXaa: 0.0 ± 0.0
Arg
2.577ArgAla: 2.577 ± 1.387
1.718ArgCys: 1.718 ± 1.082
6.014ArgAsp: 6.014 ± 2.144
2.577ArgGlu: 2.577 ± 1.168
2.577ArgPhe: 2.577 ± 1.589
2.577ArgGly: 2.577 ± 0.901
1.718ArgHis: 1.718 ± 1.327
4.296ArgIle: 4.296 ± 1.267
3.436ArgLys: 3.436 ± 1.628
5.155ArgLeu: 5.155 ± 1.106
1.718ArgMet: 1.718 ± 1.01
1.718ArgAsn: 1.718 ± 1.829
6.873ArgPro: 6.873 ± 1.927
0.859ArgGln: 0.859 ± 0.903
7.732ArgArg: 7.732 ± 4.093
5.155ArgSer: 5.155 ± 1.587
5.155ArgThr: 5.155 ± 2.121
4.296ArgVal: 4.296 ± 1.797
0.0ArgTrp: 0.0 ± 0.0
3.436ArgTyr: 3.436 ± 1.145
0.0ArgXaa: 0.0 ± 0.0
Ser
5.155SerAla: 5.155 ± 2.792
0.0SerCys: 0.0 ± 0.0
2.577SerAsp: 2.577 ± 0.901
2.577SerGlu: 2.577 ± 1.294
1.718SerPhe: 1.718 ± 0.984
3.436SerGly: 3.436 ± 1.628
2.577SerHis: 2.577 ± 2.004
3.436SerIle: 3.436 ± 0.953
5.155SerLys: 5.155 ± 1.661
4.296SerLeu: 4.296 ± 1.769
0.859SerMet: 0.859 ± 0.915
4.296SerAsn: 4.296 ± 2.385
8.591SerPro: 8.591 ± 2.517
6.014SerGln: 6.014 ± 2.959
3.436SerArg: 3.436 ± 1.335
12.887SerSer: 12.887 ± 5.4
7.732SerThr: 7.732 ± 3.607
5.155SerVal: 5.155 ± 2.256
0.859SerTrp: 0.859 ± 0.662
3.436SerTyr: 3.436 ± 1.116
0.0SerXaa: 0.0 ± 0.0
Thr
2.577ThrAla: 2.577 ± 0.958
0.859ThrCys: 0.859 ± 0.915
0.0ThrAsp: 0.0 ± 0.0
3.436ThrGlu: 3.436 ± 1.575
1.718ThrPhe: 1.718 ± 0.931
5.155ThrGly: 5.155 ± 1.666
2.577ThrHis: 2.577 ± 1.515
2.577ThrIle: 2.577 ± 1.146
1.718ThrLys: 1.718 ± 0.984
6.873ThrLeu: 6.873 ± 2.16
0.859ThrMet: 0.859 ± 0.647
2.577ThrAsn: 2.577 ± 1.179
3.436ThrPro: 3.436 ± 1.987
2.577ThrGln: 2.577 ± 1.543
4.296ThrArg: 4.296 ± 1.738
7.732ThrSer: 7.732 ± 2.457
0.0ThrThr: 0.0 ± 0.0
1.718ThrVal: 1.718 ± 1.324
0.859ThrTrp: 0.859 ± 0.915
6.014ThrTyr: 6.014 ± 2.15
0.0ThrXaa: 0.0 ± 0.0
Val
0.859ValAla: 0.859 ± 0.662
0.0ValCys: 0.0 ± 0.0
1.718ValAsp: 1.718 ± 0.965
1.718ValGlu: 1.718 ± 1.288
3.436ValPhe: 3.436 ± 2.126
2.577ValGly: 2.577 ± 1.986
1.718ValHis: 1.718 ± 0.909
4.296ValIle: 4.296 ± 2.219
6.014ValLys: 6.014 ± 2.347
3.436ValLeu: 3.436 ± 1.803
2.577ValMet: 2.577 ± 0.907
1.718ValAsn: 1.718 ± 0.965
2.577ValPro: 2.577 ± 1.205
6.014ValGln: 6.014 ± 3.73
4.296ValArg: 4.296 ± 2.181
2.577ValSer: 2.577 ± 0.831
1.718ValThr: 1.718 ± 1.324
1.718ValVal: 1.718 ± 1.082
0.859ValTrp: 0.859 ± 0.977
2.577ValTyr: 2.577 ± 0.901
0.0ValXaa: 0.0 ± 0.0
Trp
2.577TrpAla: 2.577 ± 1.94
0.859TrpCys: 0.859 ± 0.915
0.859TrpAsp: 0.859 ± 0.903
0.859TrpGlu: 0.859 ± 0.977
0.0TrpPhe: 0.0 ± 0.0
0.859TrpGly: 0.859 ± 0.647
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.859TrpMet: 0.859 ± 0.662
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.859TrpGln: 0.859 ± 0.647
1.718TrpArg: 1.718 ± 0.984
0.859TrpSer: 0.859 ± 1.006
1.718TrpThr: 1.718 ± 1.141
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.859TrpTyr: 0.859 ± 0.647
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.718TyrAla: 1.718 ± 0.705
0.0TyrCys: 0.0 ± 0.0
0.859TyrAsp: 0.859 ± 0.662
3.436TyrGlu: 3.436 ± 1.751
1.718TyrPhe: 1.718 ± 1.141
1.718TyrGly: 1.718 ± 0.705
0.0TyrHis: 0.0 ± 0.0
3.436TyrIle: 3.436 ± 1.094
0.859TyrLys: 0.859 ± 0.647
6.014TyrLeu: 6.014 ± 1.786
1.718TyrMet: 1.718 ± 1.004
2.577TyrAsn: 2.577 ± 0.907
2.577TyrPro: 2.577 ± 1.94
2.577TyrGln: 2.577 ± 1.387
4.296TyrArg: 4.296 ± 2.447
2.577TyrSer: 2.577 ± 1.316
0.859TyrThr: 0.859 ± 0.662
0.859TyrVal: 0.859 ± 0.903
0.0TyrTrp: 0.0 ± 0.0
0.859TyrTyr: 0.859 ± 1.006
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1165 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski