Amino acid dipepetide frequency for Tortoise microvirus 13

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.775AlaAla: 2.775 ± 1.289
0.555AlaCys: 0.555 ± 0.523
1.11AlaAsp: 1.11 ± 0.728
5.549AlaGlu: 5.549 ± 4.577
1.11AlaPhe: 1.11 ± 0.751
2.22AlaGly: 2.22 ± 0.891
0.0AlaHis: 0.0 ± 0.0
3.885AlaIle: 3.885 ± 1.839
3.885AlaLys: 3.885 ± 1.457
4.994AlaLeu: 4.994 ± 0.901
4.44AlaMet: 4.44 ± 1.534
2.22AlaAsn: 2.22 ± 1.446
1.11AlaPro: 1.11 ± 0.635
4.994AlaGln: 4.994 ± 2.27
1.665AlaArg: 1.665 ± 0.894
1.11AlaSer: 1.11 ± 0.728
3.885AlaThr: 3.885 ± 1.256
4.44AlaVal: 4.44 ± 1.799
1.11AlaTrp: 1.11 ± 0.728
1.11AlaTyr: 1.11 ± 0.505
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.665CysGlu: 1.665 ± 0.726
1.11CysPhe: 1.11 ± 1.198
0.555CysGly: 0.555 ± 0.523
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.11CysLeu: 1.11 ± 1.046
0.555CysMet: 0.555 ± 0.364
1.11CysAsn: 1.11 ± 0.884
0.555CysPro: 0.555 ± 0.523
0.0CysGln: 0.0 ± 0.0
1.665CysArg: 1.665 ± 0.962
0.555CysSer: 0.555 ± 0.523
1.11CysThr: 1.11 ± 1.446
2.22CysVal: 2.22 ± 1.381
0.0CysTrp: 0.0 ± 0.0
0.555CysTyr: 0.555 ± 0.364
0.0CysXaa: 0.0 ± 0.0
Asp
2.775AspAla: 2.775 ± 0.879
0.0AspCys: 0.0 ± 0.0
2.22AspAsp: 2.22 ± 1.121
3.33AspGlu: 3.33 ± 1.959
1.11AspPhe: 1.11 ± 0.635
3.33AspGly: 3.33 ± 1.548
0.555AspHis: 0.555 ± 0.523
4.44AspIle: 4.44 ± 2.424
4.44AspLys: 4.44 ± 2.581
4.44AspLeu: 4.44 ± 1.867
0.555AspMet: 0.555 ± 0.364
3.33AspAsn: 3.33 ± 1.684
1.665AspPro: 1.665 ± 0.962
1.11AspGln: 1.11 ± 0.861
0.555AspArg: 0.555 ± 0.688
1.665AspSer: 1.665 ± 0.769
3.33AspThr: 3.33 ± 1.548
1.665AspVal: 1.665 ± 1.273
1.11AspTrp: 1.11 ± 0.751
2.775AspTyr: 2.775 ± 0.888
0.0AspXaa: 0.0 ± 0.0
Glu
6.104GluAla: 6.104 ± 2.594
2.22GluCys: 2.22 ± 1.436
3.33GluAsp: 3.33 ± 1.372
12.209GluGlu: 12.209 ± 4.469
1.665GluPhe: 1.665 ± 0.737
4.44GluGly: 4.44 ± 1.404
0.555GluHis: 0.555 ± 0.812
5.549GluIle: 5.549 ± 2.571
8.324GluLys: 8.324 ± 3.89
5.549GluLeu: 5.549 ± 1.858
1.665GluMet: 1.665 ± 1.475
5.549GluAsn: 5.549 ± 1.354
1.665GluPro: 1.665 ± 0.774
4.44GluGln: 4.44 ± 2.404
6.104GluArg: 6.104 ± 1.949
4.994GluSer: 4.994 ± 1.976
6.104GluThr: 6.104 ± 1.448
6.104GluVal: 6.104 ± 2.134
1.665GluTrp: 1.665 ± 0.709
2.22GluTyr: 2.22 ± 1.185
0.0GluXaa: 0.0 ± 0.0
Phe
2.22PheAla: 2.22 ± 0.982
0.0PheCys: 0.0 ± 0.0
0.555PheAsp: 0.555 ± 0.364
2.22PheGlu: 2.22 ± 1.5
1.11PhePhe: 1.11 ± 1.541
2.775PheGly: 2.775 ± 1.336
0.0PheHis: 0.0 ± 0.0
0.555PheIle: 0.555 ± 0.523
3.33PheLys: 3.33 ± 1.181
0.0PheLeu: 0.0 ± 0.0
2.22PheMet: 2.22 ± 1.431
2.22PheAsn: 2.22 ± 1.46
0.0PhePro: 0.0 ± 0.0
2.22PheGln: 2.22 ± 0.792
0.555PheArg: 0.555 ± 0.364
1.11PheSer: 1.11 ± 0.505
3.885PheThr: 3.885 ± 0.983
1.11PheVal: 1.11 ± 0.88
0.555PheTrp: 0.555 ± 0.364
1.11PheTyr: 1.11 ± 0.728
0.0PheXaa: 0.0 ± 0.0
Gly
2.775GlyAla: 2.775 ± 1.363
0.0GlyCys: 0.0 ± 0.0
2.775GlyAsp: 2.775 ± 1.029
3.33GlyGlu: 3.33 ± 1.071
0.555GlyPhe: 0.555 ± 0.812
8.879GlyGly: 8.879 ± 3.44
1.665GlyHis: 1.665 ± 0.962
8.324GlyIle: 8.324 ± 1.883
3.33GlyLys: 3.33 ± 0.885
3.33GlyLeu: 3.33 ± 1.308
2.775GlyMet: 2.775 ± 0.871
3.885GlyAsn: 3.885 ± 2.097
1.11GlyPro: 1.11 ± 0.728
1.665GlyGln: 1.665 ± 0.514
3.33GlyArg: 3.33 ± 1.132
1.11GlySer: 1.11 ± 0.728
6.659GlyThr: 6.659 ± 1.261
4.44GlyVal: 4.44 ± 1.283
0.0GlyTrp: 0.0 ± 0.0
2.775GlyTyr: 2.775 ± 0.879
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.555HisCys: 0.555 ± 0.609
1.665HisAsp: 1.665 ± 0.962
1.665HisGlu: 1.665 ± 0.885
0.0HisPhe: 0.0 ± 0.0
0.555HisGly: 0.555 ± 0.523
0.0HisHis: 0.0 ± 0.0
1.665HisIle: 1.665 ± 0.935
2.775HisLys: 2.775 ± 0.951
2.22HisLeu: 2.22 ± 1.168
0.555HisMet: 0.555 ± 0.523
0.555HisAsn: 0.555 ± 0.364
0.555HisPro: 0.555 ± 0.364
0.555HisGln: 0.555 ± 0.523
0.0HisArg: 0.0 ± 0.0
0.555HisSer: 0.555 ± 0.523
1.665HisThr: 1.665 ± 1.199
0.555HisVal: 0.555 ± 0.364
0.555HisTrp: 0.555 ± 0.523
0.555HisTyr: 0.555 ± 0.812
0.0HisXaa: 0.0 ± 0.0
Ile
4.994IleAla: 4.994 ± 0.945
1.665IleCys: 1.665 ± 1.288
6.104IleAsp: 6.104 ± 2.09
4.44IleGlu: 4.44 ± 1.187
3.33IlePhe: 3.33 ± 1.331
7.769IleGly: 7.769 ± 1.765
1.11IleHis: 1.11 ± 0.614
4.994IleIle: 4.994 ± 2.613
9.989IleLys: 9.989 ± 2.249
2.775IleLeu: 2.775 ± 0.624
1.11IleMet: 1.11 ± 0.789
11.099IleAsn: 11.099 ± 3.489
0.555IlePro: 0.555 ± 0.364
1.665IleGln: 1.665 ± 1.608
4.44IleArg: 4.44 ± 1.084
3.33IleSer: 3.33 ± 1.869
6.104IleThr: 6.104 ± 1.83
2.775IleVal: 2.775 ± 1.201
0.555IleTrp: 0.555 ± 0.364
2.22IleTyr: 2.22 ± 2.215
0.0IleXaa: 0.0 ± 0.0
Lys
4.44LysAla: 4.44 ± 2.315
1.665LysCys: 1.665 ± 0.962
2.775LysAsp: 2.775 ± 1.86
7.214LysGlu: 7.214 ± 2.552
1.665LysPhe: 1.665 ± 1.093
5.549LysGly: 5.549 ± 1.366
2.775LysHis: 2.775 ± 1.448
7.214LysIle: 7.214 ± 2.875
14.983LysLys: 14.983 ± 5.022
9.434LysLeu: 9.434 ± 2.944
2.22LysMet: 2.22 ± 1.067
6.659LysAsn: 6.659 ± 1.27
1.11LysPro: 1.11 ± 0.635
4.994LysGln: 4.994 ± 2.002
3.33LysArg: 3.33 ± 1.214
3.885LysSer: 3.885 ± 1.467
7.769LysThr: 7.769 ± 2.921
5.549LysVal: 5.549 ± 0.955
3.33LysTrp: 3.33 ± 1.986
2.775LysTyr: 2.775 ± 1.55
0.0LysXaa: 0.0 ± 0.0
Leu
4.994LeuAla: 4.994 ± 1.977
2.22LeuCys: 2.22 ± 1.019
3.885LeuAsp: 3.885 ± 2.069
6.659LeuGlu: 6.659 ± 2.067
1.665LeuPhe: 1.665 ± 0.726
4.44LeuGly: 4.44 ± 1.183
1.11LeuHis: 1.11 ± 0.505
3.885LeuIle: 3.885 ± 1.514
5.549LeuLys: 5.549 ± 2.141
2.775LeuLeu: 2.775 ± 0.52
2.775LeuMet: 2.775 ± 0.918
4.44LeuAsn: 4.44 ± 1.489
2.775LeuPro: 2.775 ± 1.432
2.775LeuGln: 2.775 ± 1.357
3.33LeuArg: 3.33 ± 1.515
3.33LeuSer: 3.33 ± 1.871
4.994LeuThr: 4.994 ± 1.31
2.775LeuVal: 2.775 ± 0.938
0.555LeuTrp: 0.555 ± 0.523
2.775LeuTyr: 2.775 ± 0.883
0.0LeuXaa: 0.0 ± 0.0
Met
1.11MetAla: 1.11 ± 0.766
1.11MetCys: 1.11 ± 0.884
2.775MetAsp: 2.775 ± 1.051
2.22MetGlu: 2.22 ± 1.029
1.11MetPhe: 1.11 ± 0.79
3.33MetGly: 3.33 ± 1.729
0.0MetHis: 0.0 ± 0.0
1.11MetIle: 1.11 ± 1.274
2.22MetLys: 2.22 ± 2.287
3.33MetLeu: 3.33 ± 1.308
0.555MetMet: 0.555 ± 0.509
2.22MetAsn: 2.22 ± 1.229
0.0MetPro: 0.0 ± 0.0
2.775MetGln: 2.775 ± 1.545
0.555MetArg: 0.555 ± 0.523
2.775MetSer: 2.775 ± 0.879
1.665MetThr: 1.665 ± 0.709
1.11MetVal: 1.11 ± 0.516
0.555MetTrp: 0.555 ± 0.364
1.11MetTyr: 1.11 ± 0.789
0.0MetXaa: 0.0 ± 0.0
Asn
2.22AsnAla: 2.22 ± 0.673
0.0AsnCys: 0.0 ± 0.0
0.555AsnAsp: 0.555 ± 0.364
5.549AsnGlu: 5.549 ± 1.387
1.665AsnPhe: 1.665 ± 1.093
3.33AsnGly: 3.33 ± 1.018
2.22AsnHis: 2.22 ± 0.691
7.214AsnIle: 7.214 ± 1.982
8.879AsnLys: 8.879 ± 1.273
6.659AsnLeu: 6.659 ± 1.145
2.775AsnMet: 2.775 ± 0.993
4.44AsnAsn: 4.44 ± 1.679
3.33AsnPro: 3.33 ± 0.866
1.665AsnGln: 1.665 ± 0.734
4.44AsnArg: 4.44 ± 1.413
6.659AsnSer: 6.659 ± 2.437
6.659AsnThr: 6.659 ± 2.126
1.11AsnVal: 1.11 ± 0.789
3.33AsnTrp: 3.33 ± 0.913
2.775AsnTyr: 2.775 ± 1.339
0.0AsnXaa: 0.0 ± 0.0
Pro
1.665ProAla: 1.665 ± 0.734
0.555ProCys: 0.555 ± 0.364
0.555ProAsp: 0.555 ± 0.364
1.665ProGlu: 1.665 ± 1.473
0.555ProPhe: 0.555 ± 0.523
0.555ProGly: 0.555 ± 0.364
0.0ProHis: 0.0 ± 0.0
2.775ProIle: 2.775 ± 1.369
1.665ProLys: 1.665 ± 1.193
1.665ProLeu: 1.665 ± 1.093
0.0ProMet: 0.0 ± 0.0
3.885ProAsn: 3.885 ± 1.375
0.555ProPro: 0.555 ± 0.523
1.11ProGln: 1.11 ± 0.728
0.555ProArg: 0.555 ± 0.364
1.11ProSer: 1.11 ± 0.635
2.775ProThr: 2.775 ± 0.987
1.665ProVal: 1.665 ± 0.774
0.0ProTrp: 0.0 ± 0.0
0.555ProTyr: 0.555 ± 0.364
0.0ProXaa: 0.0 ± 0.0
Gln
2.775GlnAla: 2.775 ± 1.626
0.0GlnCys: 0.0 ± 0.0
0.555GlnAsp: 0.555 ± 0.364
3.885GlnGlu: 3.885 ± 0.873
1.665GlnPhe: 1.665 ± 0.734
2.775GlnGly: 2.775 ± 1.357
0.0GlnHis: 0.0 ± 0.0
3.885GlnIle: 3.885 ± 1.51
7.769GlnLys: 7.769 ± 1.724
2.775GlnLeu: 2.775 ± 0.942
0.555GlnMet: 0.555 ± 0.509
2.775GlnAsn: 2.775 ± 1.102
2.22GlnPro: 2.22 ± 0.784
0.555GlnGln: 0.555 ± 0.523
2.775GlnArg: 2.775 ± 1.379
1.665GlnSer: 1.665 ± 0.769
2.22GlnThr: 2.22 ± 0.997
1.665GlnVal: 1.665 ± 0.959
0.555GlnTrp: 0.555 ± 0.509
1.11GlnTyr: 1.11 ± 0.516
0.0GlnXaa: 0.0 ± 0.0
Arg
1.11ArgAla: 1.11 ± 0.75
1.11ArgCys: 1.11 ± 0.505
1.11ArgAsp: 1.11 ± 0.728
3.885ArgGlu: 3.885 ± 2.133
0.0ArgPhe: 0.0 ± 0.0
1.11ArgGly: 1.11 ± 0.728
1.11ArgHis: 1.11 ± 1.046
2.22ArgIle: 2.22 ± 1.457
4.994ArgLys: 4.994 ± 2.62
5.549ArgLeu: 5.549 ± 1.44
2.22ArgMet: 2.22 ± 1.209
2.775ArgAsn: 2.775 ± 1.097
0.555ArgPro: 0.555 ± 0.77
1.665ArgGln: 1.665 ± 0.709
2.22ArgArg: 2.22 ± 1.136
2.22ArgSer: 2.22 ± 1.884
3.33ArgThr: 3.33 ± 1.666
2.22ArgVal: 2.22 ± 1.185
1.11ArgTrp: 1.11 ± 0.861
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
3.33SerAla: 3.33 ± 0.813
1.11SerCys: 1.11 ± 0.752
2.775SerAsp: 2.775 ± 0.981
5.549SerGlu: 5.549 ± 2.486
0.555SerPhe: 0.555 ± 0.364
2.22SerGly: 2.22 ± 0.934
2.22SerHis: 2.22 ± 0.616
6.104SerIle: 6.104 ± 1.938
2.22SerLys: 2.22 ± 1.034
0.555SerLeu: 0.555 ± 0.723
0.0SerMet: 0.0 ± 0.0
1.665SerAsn: 1.665 ± 0.973
0.555SerPro: 0.555 ± 0.364
3.33SerGln: 3.33 ± 1.548
1.11SerArg: 1.11 ± 1.005
2.22SerSer: 2.22 ± 1.203
5.549SerThr: 5.549 ± 2.162
3.885SerVal: 3.885 ± 1.518
0.555SerTrp: 0.555 ± 0.364
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.994ThrAla: 4.994 ± 1.464
0.0ThrCys: 0.0 ± 0.0
4.44ThrAsp: 4.44 ± 2.44
9.989ThrGlu: 9.989 ± 2.309
3.885ThrPhe: 3.885 ± 2.443
4.44ThrGly: 4.44 ± 1.33
2.22ThrHis: 2.22 ± 1.034
7.214ThrIle: 7.214 ± 1.37
6.659ThrLys: 6.659 ± 1.896
2.775ThrLeu: 2.775 ± 1.339
0.555ThrMet: 0.555 ± 0.364
5.549ThrAsn: 5.549 ± 2.564
2.775ThrPro: 2.775 ± 1.336
3.885ThrGln: 3.885 ± 1.145
0.555ThrArg: 0.555 ± 0.364
2.22ThrSer: 2.22 ± 0.878
4.994ThrThr: 4.994 ± 2.707
2.775ThrVal: 2.775 ± 1.051
1.11ThrTrp: 1.11 ± 0.789
7.214ThrTyr: 7.214 ± 1.854
0.0ThrXaa: 0.0 ± 0.0
Val
2.775ValAla: 2.775 ± 1.545
0.0ValCys: 0.0 ± 0.0
3.33ValAsp: 3.33 ± 1.385
3.33ValGlu: 3.33 ± 1.832
2.775ValPhe: 2.775 ± 1.157
2.775ValGly: 2.775 ± 1.029
1.11ValHis: 1.11 ± 0.79
4.44ValIle: 4.44 ± 1.505
3.33ValLys: 3.33 ± 1.227
4.994ValLeu: 4.994 ± 1.21
2.22ValMet: 2.22 ± 0.915
4.994ValAsn: 4.994 ± 1.304
2.22ValPro: 2.22 ± 1.029
1.665ValGln: 1.665 ± 0.79
1.11ValArg: 1.11 ± 0.79
3.33ValSer: 3.33 ± 1.098
1.665ValThr: 1.665 ± 0.709
1.11ValVal: 1.11 ± 1.039
2.22ValTrp: 2.22 ± 1.019
1.11ValTyr: 1.11 ± 0.614
0.0ValXaa: 0.0 ± 0.0
Trp
0.555TrpAla: 0.555 ± 0.509
0.0TrpCys: 0.0 ± 0.0
2.22TrpAsp: 2.22 ± 1.209
3.33TrpGlu: 3.33 ± 0.933
1.11TrpPhe: 1.11 ± 0.505
0.555TrpGly: 0.555 ± 0.523
0.0TrpHis: 0.0 ± 0.0
2.22TrpIle: 2.22 ± 0.737
1.11TrpLys: 1.11 ± 0.614
1.665TrpLeu: 1.665 ± 0.709
0.555TrpMet: 0.555 ± 0.77
2.22TrpAsn: 2.22 ± 0.902
0.0TrpPro: 0.0 ± 0.0
0.555TrpGln: 0.555 ± 0.523
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.665TrpThr: 1.665 ± 1.261
2.22TrpVal: 2.22 ± 0.621
0.555TrpTrp: 0.555 ± 0.364
0.555TrpTyr: 0.555 ± 0.812
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.555TyrAla: 0.555 ± 0.364
0.0TyrCys: 0.0 ± 0.0
1.665TyrAsp: 1.665 ± 1.009
2.775TyrGlu: 2.775 ± 0.888
1.11TyrPhe: 1.11 ± 1.046
1.11TyrGly: 1.11 ± 0.516
0.555TyrHis: 0.555 ± 0.364
3.33TyrIle: 3.33 ± 1.018
3.885TyrLys: 3.885 ± 0.956
1.11TyrLeu: 1.11 ± 0.505
2.775TyrMet: 2.775 ± 1.226
3.885TyrAsn: 3.885 ± 1.303
0.555TyrPro: 0.555 ± 0.523
0.555TyrGln: 0.555 ± 0.364
2.22TyrArg: 2.22 ± 1.463
1.665TyrSer: 1.665 ± 0.734
2.22TyrThr: 2.22 ± 0.673
1.665TyrVal: 1.665 ± 0.709
1.665TyrTrp: 1.665 ± 1.18
2.22TyrTyr: 2.22 ± 0.775
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (1803 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski