Amino acid dipepetide frequency for Teredinibacter turnerae (strain ATCC 39867 / T7901)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.121AlaAla: 10.121 ± 0.118	1.119AlaCys: 1.119 ± 0.026	5.691AlaAsp: 5.691 ± 0.071	6.405AlaGlu: 6.405 ± 0.068	3.606AlaPhe: 3.606 ± 0.049	7.333AlaGly: 7.333 ± 0.097	1.922AlaHis: 1.922 ± 0.039	5.487AlaIle: 5.487 ± 0.064	4.085AlaLys: 4.085 ± 0.068	10.527AlaLeu: 10.527 ± 0.112	2.54AlaMet: 2.54 ± 0.045	3.899AlaAsn: 3.899 ± 0.067	3.813AlaPro: 3.813 ± 0.061	4.302AlaGln: 4.302 ± 0.057	5.073AlaArg: 5.073 ± 0.06	6.095AlaSer: 6.095 ± 0.079	5.009AlaThr: 5.009 ± 0.075	6.729AlaVal: 6.729 ± 0.07	1.136AlaTrp: 1.136 ± 0.027	2.698AlaTyr: 2.698 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	1.09CysAla: 1.09 ± 0.029	0.188CysCys: 0.188 ± 0.011	0.646CysAsp: 0.646 ± 0.025	0.671CysGlu: 0.671 ± 0.023	0.459CysPhe: 0.459 ± 0.02	0.977CysGly: 0.977 ± 0.03	0.309CysHis: 0.309 ± 0.017	0.556CysIle: 0.556 ± 0.019	0.37CysLys: 0.37 ± 0.017	1.052CysLeu: 1.052 ± 0.025	0.227CysMet: 0.227 ± 0.014	0.432CysAsn: 0.432 ± 0.02	0.432CysPro: 0.432 ± 0.017	0.398CysGln: 0.398 ± 0.017	0.574CysArg: 0.574 ± 0.019	0.78CysSer: 0.78 ± 0.024	0.516CysThr: 0.516 ± 0.021	0.804CysVal: 0.804 ± 0.024	0.194CysTrp: 0.194 ± 0.011	0.365CysTyr: 0.365 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	5.538AspAla: 5.538 ± 0.074	0.619AspCys: 0.619 ± 0.02	3.386AspAsp: 3.386 ± 0.066	3.718AspGlu: 3.718 ± 0.064	2.543AspPhe: 2.543 ± 0.036	4.383AspGly: 4.383 ± 0.102	1.087AspHis: 1.087 ± 0.029	3.679AspIle: 3.679 ± 0.054	2.489AspLys: 2.489 ± 0.044	5.511AspLeu: 5.511 ± 0.071	1.235AspMet: 1.235 ± 0.027	2.394AspAsn: 2.394 ± 0.057	2.443AspPro: 2.443 ± 0.046	1.972AspGln: 1.972 ± 0.038	2.653AspArg: 2.653 ± 0.046	3.614AspSer: 3.614 ± 0.079	3.126AspThr: 3.126 ± 0.058	3.942AspVal: 3.942 ± 0.055	0.919AspTrp: 0.919 ± 0.031	2.215AspTyr: 2.215 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	5.358GluAla: 5.358 ± 0.08	0.522GluCys: 0.522 ± 0.02	2.985GluAsp: 2.985 ± 0.051	3.463GluGlu: 3.463 ± 0.063	2.53GluPhe: 2.53 ± 0.036	3.594GluGly: 3.594 ± 0.057	1.532GluHis: 1.532 ± 0.032	3.795GluIle: 3.795 ± 0.056	3.261GluLys: 3.261 ± 0.06	6.675GluLeu: 6.675 ± 0.079	1.382GluMet: 1.382 ± 0.033	2.743GluAsn: 2.743 ± 0.046	2.375GluPro: 2.375 ± 0.045	3.307GluGln: 3.307 ± 0.058	3.596GluArg: 3.596 ± 0.056	3.956GluSer: 3.956 ± 0.058	3.195GluThr: 3.195 ± 0.056	3.811GluVal: 3.811 ± 0.067	0.778GluTrp: 0.778 ± 0.023	1.805GluTyr: 1.805 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.887PheAla: 3.887 ± 0.054	0.558PheCys: 0.558 ± 0.02	2.794PheAsp: 2.794 ± 0.05	2.305PheGlu: 2.305 ± 0.042	1.774PhePhe: 1.774 ± 0.036	3.101PheGly: 3.101 ± 0.052	0.861PheHis: 0.861 ± 0.023	2.262PheIle: 2.262 ± 0.039	1.54PheLys: 1.54 ± 0.034	3.444PheLeu: 3.444 ± 0.051	0.871PheMet: 0.871 ± 0.022	1.912PheAsn: 1.912 ± 0.039	1.547PhePro: 1.547 ± 0.037	1.262PheGln: 1.262 ± 0.028	1.853PheArg: 1.853 ± 0.035	3.391PheSer: 3.391 ± 0.059	2.345PheThr: 2.345 ± 0.051	2.877PheVal: 2.877 ± 0.05	0.578PheTrp: 0.578 ± 0.021	1.39PheTyr: 1.39 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	6.221GlyAla: 6.221 ± 0.088	0.917GlyCys: 0.917 ± 0.026	4.43GlyAsp: 4.43 ± 0.068	4.896GlyGlu: 4.896 ± 0.059	3.328GlyPhe: 3.328 ± 0.052	5.682GlyGly: 5.682 ± 0.111	1.486GlyHis: 1.486 ± 0.031	4.211GlyIle: 4.211 ± 0.06	3.287GlyLys: 3.287 ± 0.06	6.961GlyLeu: 6.961 ± 0.075	1.859GlyMet: 1.859 ± 0.04	2.774GlyAsn: 2.774 ± 0.059	1.947GlyPro: 1.947 ± 0.04	2.446GlyGln: 2.446 ± 0.043	3.671GlyArg: 3.671 ± 0.054	4.716GlySer: 4.716 ± 0.085	3.66GlyThr: 3.66 ± 0.068	5.745GlyVal: 5.745 ± 0.07	1.165GlyTrp: 1.165 ± 0.035	2.608GlyTyr: 2.608 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	1.79HisAla: 1.79 ± 0.032	0.337HisCys: 0.337 ± 0.017	0.988HisAsp: 0.988 ± 0.025	1.116HisGlu: 1.116 ± 0.027	1.047HisPhe: 1.047 ± 0.029	1.571HisGly: 1.571 ± 0.034	0.709HisHis: 0.709 ± 0.027	1.207HisIle: 1.207 ± 0.032	0.854HisLys: 0.854 ± 0.024	2.297HisLeu: 2.297 ± 0.037	0.465HisMet: 0.465 ± 0.018	0.877HisAsn: 0.877 ± 0.025	1.178HisPro: 1.178 ± 0.031	1.022HisGln: 1.022 ± 0.03	1.272HisArg: 1.272 ± 0.031	1.472HisSer: 1.472 ± 0.038	1.191HisThr: 1.191 ± 0.029	1.225HisVal: 1.225 ± 0.032	0.416HisTrp: 0.416 ± 0.017	0.831HisTyr: 0.831 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.208IleAla: 6.208 ± 0.068	0.636IleCys: 0.636 ± 0.022	3.777IleAsp: 3.777 ± 0.055	3.73IleGlu: 3.73 ± 0.053	2.004IlePhe: 2.004 ± 0.039	4.005IleGly: 4.005 ± 0.056	1.217IleHis: 1.217 ± 0.029	2.634IleIle: 2.634 ± 0.046	2.307IleLys: 2.307 ± 0.048	4.448IleLeu: 4.448 ± 0.06	0.98IleMet: 0.98 ± 0.029	2.54IleAsn: 2.54 ± 0.046	2.49IlePro: 2.49 ± 0.044	1.969IleGln: 1.969 ± 0.035	2.849IleArg: 2.849 ± 0.038	3.978IleSer: 3.978 ± 0.063	3.369IleThr: 3.369 ± 0.06	3.693IleVal: 3.693 ± 0.05	0.589IleTrp: 0.589 ± 0.022	1.633IleTyr: 1.633 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	3.921LysAla: 3.921 ± 0.069	0.293LysCys: 0.293 ± 0.014	2.04LysAsp: 2.04 ± 0.041	2.125LysGlu: 2.125 ± 0.049	1.313LysPhe: 1.313 ± 0.03	2.517LysGly: 2.517 ± 0.052	0.983LysHis: 0.983 ± 0.026	2.675LysIle: 2.675 ± 0.047	2.25LysLys: 2.25 ± 0.054	4.372LysLeu: 4.372 ± 0.07	0.951LysMet: 0.951 ± 0.028	1.912LysAsn: 1.912 ± 0.038	2.102LysPro: 2.102 ± 0.043	1.874LysGln: 1.874 ± 0.041	2.482LysArg: 2.482 ± 0.043	2.742LysSer: 2.742 ± 0.055	2.49LysThr: 2.49 ± 0.042	2.903LysVal: 2.903 ± 0.05	0.414LysTrp: 0.414 ± 0.017	1.222LysTyr: 1.222 ± 0.033	0.0LysXaa: 0.0 ± 0.0
Leu	11.231LeuAla: 11.231 ± 0.104	1.192LeuCys: 1.192 ± 0.027	6.085LeuAsp: 6.085 ± 0.067	6.048LeuGlu: 6.048 ± 0.074	3.936LeuPhe: 3.936 ± 0.068	6.971LeuGly: 6.971 ± 0.079	2.148LeuHis: 2.148 ± 0.038	5.036LeuIle: 5.036 ± 0.063	4.308LeuLys: 4.308 ± 0.065	10.6LeuLeu: 10.6 ± 0.123	2.272LeuMet: 2.272 ± 0.042	4.149LeuAsn: 4.149 ± 0.06	5.037LeuPro: 5.037 ± 0.076	4.298LeuGln: 4.298 ± 0.064	5.508LeuArg: 5.508 ± 0.079	7.289LeuSer: 7.289 ± 0.073	5.569LeuThr: 5.569 ± 0.071	7.311LeuVal: 7.311 ± 0.089	1.199LeuTrp: 1.199 ± 0.032	2.646LeuTyr: 2.646 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.361MetAla: 2.361 ± 0.045	0.198MetCys: 0.198 ± 0.011	1.203MetAsp: 1.203 ± 0.029	1.219MetGlu: 1.219 ± 0.034	0.775MetPhe: 0.775 ± 0.026	1.549MetGly: 1.549 ± 0.037	0.487MetHis: 0.487 ± 0.018	1.081MetIle: 1.081 ± 0.035	1.052MetLys: 1.052 ± 0.031	2.364MetLeu: 2.364 ± 0.045	0.534MetMet: 0.534 ± 0.018	0.92MetAsn: 0.92 ± 0.025	1.125MetPro: 1.125 ± 0.031	0.978MetGln: 0.978 ± 0.024	1.309MetArg: 1.309 ± 0.031	1.62MetSer: 1.62 ± 0.029	1.195MetThr: 1.195 ± 0.031	1.628MetVal: 1.628 ± 0.038	0.185MetTrp: 0.185 ± 0.01	0.478MetTyr: 0.478 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.796AsnAla: 3.796 ± 0.064	0.473AsnCys: 0.473 ± 0.02	2.175AsnAsp: 2.175 ± 0.056	2.087AsnGlu: 2.087 ± 0.039	1.626AsnPhe: 1.626 ± 0.036	3.179AsnGly: 3.179 ± 0.069	0.864AsnHis: 0.864 ± 0.024	2.515AsnIle: 2.515 ± 0.047	1.552AsnLys: 1.552 ± 0.038	4.021AsnLeu: 4.021 ± 0.057	0.849AsnMet: 0.849 ± 0.025	1.831AsnAsn: 1.831 ± 0.045	2.238AsnPro: 2.238 ± 0.04	1.654AsnGln: 1.654 ± 0.037	2.25AsnArg: 2.25 ± 0.04	2.799AsnSer: 2.799 ± 0.055	2.47AsnThr: 2.47 ± 0.049	2.42AsnVal: 2.42 ± 0.044	0.687AsnTrp: 0.687 ± 0.026	1.435AsnTyr: 1.435 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	4.462ProAla: 4.462 ± 0.07	0.348ProCys: 0.348 ± 0.017	2.659ProAsp: 2.659 ± 0.049	3.389ProGlu: 3.389 ± 0.054	1.713ProPhe: 1.713 ± 0.032	3.197ProGly: 3.197 ± 0.058	0.874ProHis: 0.874 ± 0.025	2.13ProIle: 2.13 ± 0.043	1.595ProLys: 1.595 ± 0.031	4.548ProLeu: 4.548 ± 0.068	0.916ProMet: 0.916 ± 0.024	1.603ProAsn: 1.603 ± 0.036	1.693ProPro: 1.693 ± 0.038	1.885ProGln: 1.885 ± 0.04	1.774ProArg: 1.774 ± 0.036	2.707ProSer: 2.707 ± 0.059	2.28ProThr: 2.28 ± 0.051	3.612ProVal: 3.612 ± 0.053	0.577ProTrp: 0.577 ± 0.018	1.188ProTyr: 1.188 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.165GlnAla: 4.165 ± 0.056	0.394GlnCys: 0.394 ± 0.018	1.746GlnAsp: 1.746 ± 0.036	2.17GlnGlu: 2.17 ± 0.038	1.624GlnPhe: 1.624 ± 0.033	2.586GlnGly: 2.586 ± 0.045	1.067GlnHis: 1.067 ± 0.03	2.259GlnIle: 2.259 ± 0.041	1.756GlnLys: 1.756 ± 0.036	4.94GlnLeu: 4.94 ± 0.075	0.965GlnMet: 0.965 ± 0.024	1.515GlnAsn: 1.515 ± 0.032	1.966GlnPro: 1.966 ± 0.035	2.644GlnGln: 2.644 ± 0.059	2.559GlnArg: 2.559 ± 0.045	2.575GlnSer: 2.575 ± 0.038	2.203GlnThr: 2.203 ± 0.046	3.014GlnVal: 3.014 ± 0.048	0.681GlnTrp: 0.681 ± 0.023	1.14GlnTyr: 1.14 ± 0.028	0.001GlnXaa: 0.001 ± 0.001
Arg	4.771ArgAla: 4.771 ± 0.058	0.559ArgCys: 0.559 ± 0.021	3.017ArgAsp: 3.017 ± 0.053	3.651ArgGlu: 3.651 ± 0.061	2.51ArgPhe: 2.51 ± 0.043	3.269ArgGly: 3.269 ± 0.045	1.221ArgHis: 1.221 ± 0.029	3.047ArgIle: 3.047 ± 0.05	2.383ArgLys: 2.383 ± 0.042	5.766ArgLeu: 5.766 ± 0.076	1.274ArgMet: 1.274 ± 0.031	2.079ArgAsn: 2.079 ± 0.041	1.912ArgPro: 1.912 ± 0.039	2.234ArgGln: 2.234 ± 0.042	2.804ArgArg: 2.804 ± 0.056	3.098ArgSer: 3.098 ± 0.045	2.526ArgThr: 2.526 ± 0.044	3.822ArgVal: 3.822 ± 0.049	0.906ArgTrp: 0.906 ± 0.03	1.963ArgTyr: 1.963 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	6.707SerAla: 6.707 ± 0.084	0.737SerCys: 0.737 ± 0.024	3.898SerAsp: 3.898 ± 0.069	3.942SerGlu: 3.942 ± 0.058	2.689SerPhe: 2.689 ± 0.051	5.729SerGly: 5.729 ± 0.1	1.47SerHis: 1.47 ± 0.034	3.509SerIle: 3.509 ± 0.062	2.313SerLys: 2.313 ± 0.049	6.892SerLeu: 6.892 ± 0.086	1.416SerMet: 1.416 ± 0.03	2.559SerAsn: 2.559 ± 0.048	2.88SerPro: 2.88 ± 0.053	2.627SerGln: 2.627 ± 0.041	3.46SerArg: 3.46 ± 0.05	6.783SerSer: 6.783 ± 0.371	3.544SerThr: 3.544 ± 0.06	4.862SerVal: 4.862 ± 0.073	0.95SerTrp: 0.95 ± 0.028	2.056SerTyr: 2.056 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	5.188ThrAla: 5.188 ± 0.075	0.526ThrCys: 0.526 ± 0.022	3.07ThrAsp: 3.07 ± 0.062	3.024ThrGlu: 3.024 ± 0.047	2.088ThrPhe: 2.088 ± 0.045	4.405ThrGly: 4.405 ± 0.077	1.201ThrHis: 1.201 ± 0.027	2.807ThrIle: 2.807 ± 0.05	1.66ThrLys: 1.66 ± 0.044	6.317ThrLeu: 6.317 ± 0.082	0.962ThrMet: 0.962 ± 0.025	1.972ThrAsn: 1.972 ± 0.047	3.102ThrPro: 3.102 ± 0.062	2.236ThrGln: 2.236 ± 0.042	2.666ThrArg: 2.666 ± 0.047	3.478ThrSer: 3.478 ± 0.057	3.002ThrThr: 3.002 ± 0.055	3.999ThrVal: 3.999 ± 0.065	0.664ThrTrp: 0.664 ± 0.02	1.603ThrTyr: 1.603 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	7.248ValAla: 7.248 ± 0.089	0.867ValCys: 0.867 ± 0.028	4.501ValAsp: 4.501 ± 0.063	4.379ValGlu: 4.379 ± 0.056	2.965ValPhe: 2.965 ± 0.048	4.821ValGly: 4.821 ± 0.062	1.366ValHis: 1.366 ± 0.034	4.02ValIle: 4.02 ± 0.053	2.949ValLys: 2.949 ± 0.056	6.938ValLeu: 6.938 ± 0.085	1.618ValMet: 1.618 ± 0.039	3.039ValAsn: 3.039 ± 0.054	2.953ValPro: 2.953 ± 0.05	2.341ValGln: 2.341 ± 0.04	3.503ValArg: 3.503 ± 0.05	4.923ValSer: 4.923 ± 0.068	4.011ValThr: 4.011 ± 0.059	5.621ValVal: 5.621 ± 0.075	0.818ValTrp: 0.818 ± 0.027	1.997ValTyr: 1.997 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	0.938TrpAla: 0.938 ± 0.029	0.17TrpCys: 0.17 ± 0.01	0.672TrpAsp: 0.672 ± 0.023	0.681TrpGlu: 0.681 ± 0.026	0.566TrpPhe: 0.566 ± 0.021	0.905TrpGly: 0.905 ± 0.029	0.373TrpHis: 0.373 ± 0.016	0.644TrpIle: 0.644 ± 0.025	0.453TrpLys: 0.453 ± 0.018	1.839TrpLeu: 1.839 ± 0.037	0.317TrpMet: 0.317 ± 0.013	0.569TrpAsn: 0.569 ± 0.022	0.544TrpPro: 0.544 ± 0.019	1.016TrpGln: 1.016 ± 0.026	0.888TrpArg: 0.888 ± 0.025	0.887TrpSer: 0.887 ± 0.025	0.558TrpThr: 0.558 ± 0.021	0.931TrpVal: 0.931 ± 0.03	0.23TrpTrp: 0.23 ± 0.013	0.425TrpTyr: 0.425 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.588TyrAla: 2.588 ± 0.048	0.387TyrCys: 0.387 ± 0.017	1.705TyrAsp: 1.705 ± 0.037	1.645TyrGlu: 1.645 ± 0.033	1.461TyrPhe: 1.461 ± 0.038	2.236TyrGly: 2.236 ± 0.039	0.685TyrHis: 0.685 ± 0.024	1.501TyrIle: 1.501 ± 0.034	1.115TyrLys: 1.115 ± 0.029	3.321TyrLeu: 3.321 ± 0.046	0.626TyrMet: 0.626 ± 0.022	1.2TyrAsn: 1.2 ± 0.029	1.374TyrPro: 1.374 ± 0.029	1.506TyrGln: 1.506 ± 0.035	2.066TyrArg: 2.066 ± 0.04	2.12TyrSer: 2.12 ± 0.042	1.709TyrThr: 1.709 ± 0.036	1.931TyrVal: 1.931 ± 0.041	0.523TyrTrp: 0.523 ± 0.019	1.065TyrTyr: 1.065 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.001	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4249 proteins (1491791 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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