Human polyomavirus 7

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Sepolyvirales; Polyomaviridae; Deltapolyomavirus

Average proteome isoelectric point is 6.36

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|D6QWK4|D6QWK4_9POLY VP3 OS=Human polyomavirus 7 OX=746831 PE=4 SV=1
MM1 pKa = 7.79GILLSIPEE9 pKa = 4.83IIAATAIGGGEE20 pKa = 3.99ALEE23 pKa = 4.34IAGSVGALVSGEE35 pKa = 3.95GLATLEE41 pKa = 4.35ALQSAAALSTEE52 pKa = 3.89ATAALAVSNEE62 pKa = 3.62AAIVLSTIPEE72 pKa = 4.44LSQTLFGVQTLLSSVAGVGGVVYY95 pKa = 10.58NLNPGEE101 pKa = 4.73LYY103 pKa = 10.01QAPEE107 pKa = 4.58GPGGLGPRR115 pKa = 11.84IGSTTMALQLWLPQAWPWGGAAGGVPDD142 pKa = 4.21WLLEE146 pKa = 3.97VLRR149 pKa = 11.84EE150 pKa = 4.07VPTPSEE156 pKa = 3.52ILYY159 pKa = 10.62NIARR163 pKa = 11.84GIWTSYY169 pKa = 9.21YY170 pKa = 8.51RR171 pKa = 11.84TGRR174 pKa = 11.84EE175 pKa = 3.97LIQRR179 pKa = 11.84TATRR183 pKa = 11.84EE184 pKa = 3.93LASLLSRR191 pKa = 11.84LRR193 pKa = 11.84QNIINGANRR202 pKa = 11.84AIEE205 pKa = 4.09MAPDD209 pKa = 4.13PVQGLLNLINQAIAYY224 pKa = 8.64NRR226 pKa = 11.84DD227 pKa = 2.72WEE229 pKa = 4.43TRR231 pKa = 11.84ALLEE235 pKa = 4.09GRR237 pKa = 11.84PLFEE241 pKa = 5.23PGGVVMYY248 pKa = 7.47DD249 pKa = 3.52TQNLPLSGNNDD260 pKa = 3.2QRR262 pKa = 11.84GGFHH266 pKa = 7.89DD267 pKa = 3.98EE268 pKa = 4.24GTWVSFQGEE277 pKa = 4.36EE278 pKa = 4.61GNTPQYY284 pKa = 10.0TIPQWMLFVLEE295 pKa = 4.25EE296 pKa = 4.03LQKK299 pKa = 10.89EE300 pKa = 4.4VNKK303 pKa = 10.19EE304 pKa = 3.78NKK306 pKa = 9.31HH307 pKa = 5.51ALSKK311 pKa = 9.56KK312 pKa = 10.02RR313 pKa = 11.84KK314 pKa = 4.89WTSTEE319 pKa = 3.71TSQSDD324 pKa = 3.26KK325 pKa = 10.72KK326 pKa = 10.68RR327 pKa = 11.84RR328 pKa = 11.84RR329 pKa = 3.43

Molecular weight: 35.52 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|D6QWK7|D6QWK7_9POLY Small T antigen OS=Human polyomavirus 7 OX=746831 PE=4 SV=1
MM1 pKa = 8.07DD2 pKa = 5.38KK3 pKa = 11.01LLGRR7 pKa = 11.84DD8 pKa = 3.48EE9 pKa = 4.66VKK11 pKa = 10.95EE12 pKa = 3.76LMEE15 pKa = 5.59LIGLNMACWGNLPLIQHH32 pKa = 6.46KK33 pKa = 10.38VRR35 pKa = 11.84LASKK39 pKa = 10.08KK40 pKa = 7.62YY41 pKa = 10.1HH42 pKa = 6.72PDD44 pKa = 3.38KK45 pKa = 11.5GGDD48 pKa = 3.58PQKK51 pKa = 9.93MQRR54 pKa = 11.84LNVLKK59 pKa = 10.64DD60 pKa = 3.3KK61 pKa = 11.65LEE63 pKa = 4.06ATLRR67 pKa = 11.84DD68 pKa = 3.77QRR70 pKa = 11.84SGSPMWHH77 pKa = 6.02YY78 pKa = 11.43SSDD81 pKa = 3.61EE82 pKa = 3.85VSFWDD87 pKa = 3.34IEE89 pKa = 4.34LTVGEE94 pKa = 4.22FLGPEE99 pKa = 4.39FNRR102 pKa = 11.84KK103 pKa = 8.79KK104 pKa = 9.25VWNYY108 pKa = 9.47NLCVVQGLRR117 pKa = 11.84ACCCIHH123 pKa = 7.32CILKK127 pKa = 10.42RR128 pKa = 11.84KK129 pKa = 8.92HH130 pKa = 5.68KK131 pKa = 10.48KK132 pKa = 8.78KK133 pKa = 10.31AKK135 pKa = 9.99EE136 pKa = 3.67YY137 pKa = 10.85AKK139 pKa = 10.31DD140 pKa = 3.5QRR142 pKa = 11.84GPLSWGKK149 pKa = 9.43CWCFHH154 pKa = 7.43CYY156 pKa = 10.54LNWFGVEE163 pKa = 3.77RR164 pKa = 11.84SEE166 pKa = 5.27EE167 pKa = 4.16SFMWWSHH174 pKa = 6.86IIFQTPMDD182 pKa = 4.2VLNLWGQLNLLL193 pKa = 4.33

Molecular weight: 22.8 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

0

5

1781

193

671

356.2

39.74

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.468 ± 0.75

2.021 ± 0.691

4.323 ± 0.596

6.906 ± 0.505

3.144 ± 0.439

7.973 ± 0.894

1.46 ± 0.411

4.267 ± 0.315

6.176 ± 1.302

10.668 ± 0.597

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.751 ± 0.314

4.997 ± 0.211

5.783 ± 0.686

4.941 ± 0.537

4.604 ± 0.816

5.727 ± 0.439

5.334 ± 0.734

6.008 ± 0.561

2.471 ± 0.595

2.976 ± 0.138
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski