Amino acid dipepetide frequency for Tersicoccus phoenicis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.681AlaAla: 21.681 ± 0.274	0.811AlaCys: 0.811 ± 0.033	9.105AlaAsp: 9.105 ± 0.124	7.636AlaGlu: 7.636 ± 0.116	3.623AlaPhe: 3.623 ± 0.067	14.199AlaGly: 14.199 ± 0.156	2.652AlaHis: 2.652 ± 0.057	4.57AlaIle: 4.57 ± 0.076	2.346AlaLys: 2.346 ± 0.058	13.681AlaLeu: 13.681 ± 0.154	2.499AlaMet: 2.499 ± 0.048	2.332AlaAsn: 2.332 ± 0.059	6.448AlaPro: 6.448 ± 0.119	3.882AlaGln: 3.882 ± 0.069	10.291AlaArg: 10.291 ± 0.141	6.51AlaSer: 6.51 ± 0.089	7.935AlaThr: 7.935 ± 0.091	12.999AlaVal: 12.999 ± 0.149	1.897AlaTrp: 1.897 ± 0.047	2.213AlaTyr: 2.213 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.729CysAla: 0.729 ± 0.029	0.073CysCys: 0.073 ± 0.01	0.321CysAsp: 0.321 ± 0.019	0.285CysGlu: 0.285 ± 0.017	0.168CysPhe: 0.168 ± 0.012	0.706CysGly: 0.706 ± 0.032	0.139CysHis: 0.139 ± 0.012	0.198CysIle: 0.198 ± 0.015	0.077CysLys: 0.077 ± 0.01	0.558CysLeu: 0.558 ± 0.023	0.088CysMet: 0.088 ± 0.009	0.1CysAsn: 0.1 ± 0.011	0.363CysPro: 0.363 ± 0.022	0.144CysGln: 0.144 ± 0.012	0.495CysArg: 0.495 ± 0.026	0.32CysSer: 0.32 ± 0.019	0.386CysThr: 0.386 ± 0.022	0.483CysVal: 0.483 ± 0.023	0.124CysTrp: 0.124 ± 0.01	0.129CysTyr: 0.129 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	9.313AspAla: 9.313 ± 0.119	0.271AspCys: 0.271 ± 0.018	4.202AspAsp: 4.202 ± 0.084	3.907AspGlu: 3.907 ± 0.072	1.599AspPhe: 1.599 ± 0.042	6.494AspGly: 6.494 ± 0.093	1.42AspHis: 1.42 ± 0.043	1.974AspIle: 1.974 ± 0.049	0.926AspLys: 0.926 ± 0.036	6.685AspLeu: 6.685 ± 0.096	0.796AspMet: 0.796 ± 0.03	0.83AspAsn: 0.83 ± 0.033	4.678AspPro: 4.678 ± 0.089	1.705AspGln: 1.705 ± 0.043	5.417AspArg: 5.417 ± 0.072	2.2AspSer: 2.2 ± 0.042	3.116AspThr: 3.116 ± 0.055	5.963AspVal: 5.963 ± 0.092	0.887AspTrp: 0.887 ± 0.031	1.133AspTyr: 1.133 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	6.491GluAla: 6.491 ± 0.1	0.209GluCys: 0.209 ± 0.015	2.935GluAsp: 2.935 ± 0.063	2.704GluGlu: 2.704 ± 0.074	1.357GluPhe: 1.357 ± 0.048	3.362GluGly: 3.362 ± 0.062	1.616GluHis: 1.616 ± 0.047	2.044GluIle: 2.044 ± 0.053	1.292GluLys: 1.292 ± 0.043	5.878GluLeu: 5.878 ± 0.098	0.826GluMet: 0.826 ± 0.034	1.2GluAsn: 1.2 ± 0.036	2.931GluPro: 2.931 ± 0.065	2.31GluGln: 2.31 ± 0.048	4.892GluArg: 4.892 ± 0.087	2.392GluSer: 2.392 ± 0.056	2.772GluThr: 2.772 ± 0.06	3.942GluVal: 3.942 ± 0.069	0.58GluTrp: 0.58 ± 0.026	1.014GluTyr: 1.014 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.942PheAla: 3.942 ± 0.077	0.208PheCys: 0.208 ± 0.013	2.141PheAsp: 2.141 ± 0.053	1.342PheGlu: 1.342 ± 0.038	0.938PhePhe: 0.938 ± 0.037	3.163PheGly: 3.163 ± 0.069	0.563PheHis: 0.563 ± 0.026	1.014PheIle: 1.014 ± 0.037	0.445PheLys: 0.445 ± 0.021	2.631PheLeu: 2.631 ± 0.066	0.423PheMet: 0.423 ± 0.02	0.61PheAsn: 0.61 ± 0.029	1.276PhePro: 1.276 ± 0.038	0.64PheGln: 0.64 ± 0.025	1.742PheArg: 1.742 ± 0.052	1.721PheSer: 1.721 ± 0.053	2.161PheThr: 2.161 ± 0.05	2.469PheVal: 2.469 ± 0.062	0.396PheTrp: 0.396 ± 0.021	0.601PheTyr: 0.601 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	11.189GlyAla: 11.189 ± 0.145	0.601GlyCys: 0.601 ± 0.028	4.981GlyAsp: 4.981 ± 0.09	4.431GlyGlu: 4.431 ± 0.077	2.979GlyPhe: 2.979 ± 0.055	7.976GlyGly: 7.976 ± 0.116	2.027GlyHis: 2.027 ± 0.047	3.941GlyIle: 3.941 ± 0.069	2.119GlyLys: 2.119 ± 0.062	9.165GlyLeu: 9.165 ± 0.111	1.983GlyMet: 1.983 ± 0.051	1.894GlyAsn: 1.894 ± 0.054	4.831GlyPro: 4.831 ± 0.085	2.959GlyGln: 2.959 ± 0.067	7.697GlyArg: 7.697 ± 0.087	5.71GlySer: 5.71 ± 0.099	6.424GlyThr: 6.424 ± 0.114	8.071GlyVal: 8.071 ± 0.112	1.683GlyTrp: 1.683 ± 0.043	2.202GlyTyr: 2.202 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.543HisAla: 2.543 ± 0.055	0.144HisCys: 0.144 ± 0.013	1.427HisAsp: 1.427 ± 0.04	1.117HisGlu: 1.117 ± 0.036	0.503HisPhe: 0.503 ± 0.026	2.226HisGly: 2.226 ± 0.051	0.659HisHis: 0.659 ± 0.03	0.572HisIle: 0.572 ± 0.023	0.26HisLys: 0.26 ± 0.017	2.259HisLeu: 2.259 ± 0.052	0.286HisMet: 0.286 ± 0.016	0.324HisAsn: 0.324 ± 0.019	1.619HisPro: 1.619 ± 0.046	0.644HisGln: 0.644 ± 0.028	2.146HisArg: 2.146 ± 0.048	0.832HisSer: 0.832 ± 0.03	1.161HisThr: 1.161 ± 0.039	1.872HisVal: 1.872 ± 0.051	0.327HisTrp: 0.327 ± 0.021	0.399HisTyr: 0.399 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.568IleAla: 5.568 ± 0.085	0.299IleCys: 0.299 ± 0.015	2.887IleAsp: 2.887 ± 0.058	2.246IleGlu: 2.246 ± 0.051	0.943IlePhe: 0.943 ± 0.035	4.165IleGly: 4.165 ± 0.086	0.634IleHis: 0.634 ± 0.028	1.321IleIle: 1.321 ± 0.041	0.75IleLys: 0.75 ± 0.031	2.933IleLeu: 2.933 ± 0.061	0.536IleMet: 0.536 ± 0.023	0.905IleAsn: 0.905 ± 0.032	1.998IlePro: 1.998 ± 0.045	0.8IleGln: 0.8 ± 0.036	2.428IleArg: 2.428 ± 0.052	2.054IleSer: 2.054 ± 0.052	2.673IleThr: 2.673 ± 0.064	3.571IleVal: 3.571 ± 0.061	0.374IleTrp: 0.374 ± 0.021	0.639IleTyr: 0.639 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	2.265LysAla: 2.265 ± 0.063	0.075LysCys: 0.075 ± 0.008	1.172LysAsp: 1.172 ± 0.038	0.908LysGlu: 0.908 ± 0.035	0.425LysPhe: 0.425 ± 0.021	1.393LysGly: 1.393 ± 0.053	0.423LysHis: 0.423 ± 0.022	0.834LysIle: 0.834 ± 0.035	0.677LysLys: 0.677 ± 0.036	1.716LysLeu: 1.716 ± 0.048	0.351LysMet: 0.351 ± 0.019	0.513LysAsn: 0.513 ± 0.026	1.161LysPro: 1.161 ± 0.04	0.656LysGln: 0.656 ± 0.031	1.346LysArg: 1.346 ± 0.043	0.946LysSer: 0.946 ± 0.038	1.194LysThr: 1.194 ± 0.043	1.601LysVal: 1.601 ± 0.046	0.192LysTrp: 0.192 ± 0.016	0.422LysTyr: 0.422 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	15.152LeuAla: 15.152 ± 0.17	0.614LeuCys: 0.614 ± 0.025	6.809LeuAsp: 6.809 ± 0.09	4.228LeuGlu: 4.228 ± 0.078	2.655LeuPhe: 2.655 ± 0.066	9.036LeuGly: 9.036 ± 0.1	2.135LeuHis: 2.135 ± 0.044	4.18LeuIle: 4.18 ± 0.079	1.689LeuLys: 1.689 ± 0.049	10.518LeuLeu: 10.518 ± 0.141	1.629LeuMet: 1.629 ± 0.043	1.927LeuAsn: 1.927 ± 0.056	5.867LeuPro: 5.867 ± 0.084	2.672LeuGln: 2.672 ± 0.055	7.822LeuArg: 7.822 ± 0.105	5.234LeuSer: 5.234 ± 0.077	7.071LeuThr: 7.071 ± 0.089	8.995LeuVal: 8.995 ± 0.101	1.163LeuTrp: 1.163 ± 0.038	1.703LeuTyr: 1.703 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.28MetAla: 2.28 ± 0.057	0.126MetCys: 0.126 ± 0.011	0.905MetAsp: 0.905 ± 0.034	0.642MetGlu: 0.642 ± 0.03	0.51MetPhe: 0.51 ± 0.024	1.344MetGly: 1.344 ± 0.046	0.313MetHis: 0.313 ± 0.019	0.796MetIle: 0.796 ± 0.029	0.416MetLys: 0.416 ± 0.021	1.766MetLeu: 1.766 ± 0.047	0.323MetMet: 0.323 ± 0.022	0.463MetAsn: 0.463 ± 0.021	1.078MetPro: 1.078 ± 0.038	0.46MetGln: 0.46 ± 0.024	1.266MetArg: 1.266 ± 0.037	1.421MetSer: 1.421 ± 0.042	1.582MetThr: 1.582 ± 0.043	1.431MetVal: 1.431 ± 0.039	0.184MetTrp: 0.184 ± 0.014	0.269MetTyr: 0.269 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.538AsnAla: 2.538 ± 0.066	0.117AsnCys: 0.117 ± 0.011	1.052AsnAsp: 1.052 ± 0.036	0.873AsnGlu: 0.873 ± 0.029	0.539AsnPhe: 0.539 ± 0.024	1.891AsnGly: 1.891 ± 0.051	0.412AsnHis: 0.412 ± 0.021	0.7AsnIle: 0.7 ± 0.031	0.395AsnLys: 0.395 ± 0.025	1.989AsnLeu: 1.989 ± 0.053	0.286AsnMet: 0.286 ± 0.019	0.503AsnAsn: 0.503 ± 0.026	1.523AsnPro: 1.523 ± 0.044	0.656AsnGln: 0.656 ± 0.026	1.508AsnArg: 1.508 ± 0.037	0.903AsnSer: 0.903 ± 0.031	1.15AsnThr: 1.15 ± 0.04	1.6AsnVal: 1.6 ± 0.044	0.298AsnTrp: 0.298 ± 0.019	0.412AsnTyr: 0.412 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	8.311ProAla: 8.311 ± 0.13	0.248ProCys: 0.248 ± 0.018	4.453ProAsp: 4.453 ± 0.078	3.437ProGlu: 3.437 ± 0.068	1.585ProPhe: 1.585 ± 0.043	6.119ProGly: 6.119 ± 0.106	1.117ProHis: 1.117 ± 0.035	1.649ProIle: 1.649 ± 0.041	0.853ProLys: 0.853 ± 0.037	4.808ProLeu: 4.808 ± 0.072	0.936ProMet: 0.936 ± 0.031	0.969ProAsn: 0.969 ± 0.031	2.513ProPro: 2.513 ± 0.062	1.464ProGln: 1.464 ± 0.043	3.733ProArg: 3.733 ± 0.07	3.111ProSer: 3.111 ± 0.069	3.743ProThr: 3.743 ± 0.07	5.771ProVal: 5.771 ± 0.086	0.893ProTrp: 0.893 ± 0.033	1.005ProTyr: 1.005 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.743GlnAla: 3.743 ± 0.082	0.154GlnCys: 0.154 ± 0.011	1.476GlnAsp: 1.476 ± 0.04	1.278GlnGlu: 1.278 ± 0.041	0.848GlnPhe: 0.848 ± 0.032	2.042GlnGly: 2.042 ± 0.052	0.695GlnHis: 0.695 ± 0.027	1.35GlnIle: 1.35 ± 0.037	0.619GlnLys: 0.619 ± 0.028	3.265GlnLeu: 3.265 ± 0.058	0.552GlnMet: 0.552 ± 0.025	0.632GlnAsn: 0.632 ± 0.031	1.602GlnPro: 1.602 ± 0.042	1.34GlnGln: 1.34 ± 0.048	2.686GlnArg: 2.686 ± 0.063	1.291GlnSer: 1.291 ± 0.041	1.636GlnThr: 1.636 ± 0.042	2.576GlnVal: 2.576 ± 0.053	0.468GlnTrp: 0.468 ± 0.025	0.648GlnTyr: 0.648 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	9.726ArgAla: 9.726 ± 0.132	0.434ArgCys: 0.434 ± 0.024	4.556ArgAsp: 4.556 ± 0.074	4.113ArgGlu: 4.113 ± 0.072	2.479ArgPhe: 2.479 ± 0.051	5.807ArgGly: 5.807 ± 0.095	1.929ArgHis: 1.929 ± 0.051	3.352ArgIle: 3.352 ± 0.061	1.371ArgLys: 1.371 ± 0.047	8.499ArgLeu: 8.499 ± 0.113	1.832ArgMet: 1.832 ± 0.044	1.525ArgAsn: 1.525 ± 0.044	4.623ArgPro: 4.623 ± 0.085	2.588ArgGln: 2.588 ± 0.061	7.918ArgArg: 7.918 ± 0.122	4.407ArgSer: 4.407 ± 0.064	5.062ArgThr: 5.062 ± 0.079	6.249ArgVal: 6.249 ± 0.088	1.446ArgTrp: 1.446 ± 0.044	1.724ArgTyr: 1.724 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	7.097SerAla: 7.097 ± 0.098	0.288SerCys: 0.288 ± 0.018	2.649SerAsp: 2.649 ± 0.054	2.267SerGlu: 2.267 ± 0.046	1.651SerPhe: 1.651 ± 0.047	5.631SerGly: 5.631 ± 0.096	0.859SerHis: 0.859 ± 0.035	1.929SerIle: 1.929 ± 0.051	0.875SerLys: 0.875 ± 0.029	4.912SerLeu: 4.912 ± 0.077	1.131SerMet: 1.131 ± 0.034	0.902SerAsn: 0.902 ± 0.032	3.133SerPro: 3.133 ± 0.071	1.185SerGln: 1.185 ± 0.04	4.144SerArg: 4.144 ± 0.076	3.212SerSer: 3.212 ± 0.064	3.773SerThr: 3.773 ± 0.067	4.425SerVal: 4.425 ± 0.081	0.864SerTrp: 0.864 ± 0.028	1.046SerTyr: 1.046 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	9.145ThrAla: 9.145 ± 0.132	0.347ThrCys: 0.347 ± 0.017	4.269ThrAsp: 4.269 ± 0.072	3.135ThrGlu: 3.135 ± 0.052	1.738ThrPhe: 1.738 ± 0.05	7.179ThrGly: 7.179 ± 0.091	1.145ThrHis: 1.145 ± 0.038	2.337ThrIle: 2.337 ± 0.05	1.021ThrLys: 1.021 ± 0.032	5.719ThrLeu: 5.719 ± 0.081	1.113ThrMet: 1.113 ± 0.043	1.108ThrAsn: 1.108 ± 0.037	3.966ThrPro: 3.966 ± 0.072	1.388ThrGln: 1.388 ± 0.046	4.278ThrArg: 4.278 ± 0.07	3.436ThrSer: 3.436 ± 0.066	4.46ThrThr: 4.46 ± 0.078	6.689ThrVal: 6.689 ± 0.097	0.871ThrTrp: 0.871 ± 0.032	1.207ThrTyr: 1.207 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	11.67ValAla: 11.67 ± 0.15	0.622ValCys: 0.622 ± 0.029	6.088ValAsp: 6.088 ± 0.096	4.633ValGlu: 4.633 ± 0.086	2.701ValPhe: 2.701 ± 0.06	7.35ValGly: 7.35 ± 0.096	1.948ValHis: 1.948 ± 0.05	3.839ValIle: 3.839 ± 0.073	1.589ValLys: 1.589 ± 0.051	10.209ValLeu: 10.209 ± 0.118	1.48ValMet: 1.48 ± 0.042	1.81ValAsn: 1.81 ± 0.048	5.345ValPro: 5.345 ± 0.09	2.223ValGln: 2.223 ± 0.053	6.697ValArg: 6.697 ± 0.085	4.513ValSer: 4.513 ± 0.075	6.163ValThr: 6.163 ± 0.089	9.406ValVal: 9.406 ± 0.11	1.001ValTrp: 1.001 ± 0.033	1.514ValTyr: 1.514 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.603TrpAla: 1.603 ± 0.046	0.138TrpCys: 0.138 ± 0.012	0.836TrpAsp: 0.836 ± 0.034	0.588TrpGlu: 0.588 ± 0.026	0.556TrpPhe: 0.556 ± 0.029	0.98TrpGly: 0.98 ± 0.036	0.302TrpHis: 0.302 ± 0.016	0.572TrpIle: 0.572 ± 0.029	0.243TrpLys: 0.243 ± 0.017	1.753TrpLeu: 1.753 ± 0.046	0.293TrpMet: 0.293 ± 0.018	0.391TrpAsn: 0.391 ± 0.021	0.697TrpPro: 0.697 ± 0.028	0.549TrpGln: 0.549 ± 0.022	1.308TrpArg: 1.308 ± 0.041	0.812TrpSer: 0.812 ± 0.033	0.87TrpThr: 0.87 ± 0.032	1.167TrpVal: 1.167 ± 0.034	0.327TrpTrp: 0.327 ± 0.023	0.306TrpTyr: 0.306 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.325TyrAla: 2.325 ± 0.051	0.111TyrCys: 0.111 ± 0.011	1.25TyrAsp: 1.25 ± 0.04	0.979TyrGlu: 0.979 ± 0.037	0.626TyrPhe: 0.626 ± 0.031	1.799TyrGly: 1.799 ± 0.046	0.336TyrHis: 0.336 ± 0.019	0.55TyrIle: 0.55 ± 0.028	0.308TyrLys: 0.308 ± 0.019	2.153TyrLeu: 2.153 ± 0.053	0.211TyrMet: 0.211 ± 0.016	0.411TyrAsn: 0.411 ± 0.022	1.068TyrPro: 1.068 ± 0.037	0.635TyrGln: 0.635 ± 0.028	1.824TyrArg: 1.824 ± 0.044	0.946TyrSer: 0.946 ± 0.034	1.218TyrThr: 1.218 ± 0.039	1.518TyrVal: 1.518 ± 0.043	0.315TyrTrp: 0.315 ± 0.018	0.46TyrTyr: 0.46 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2865 proteins (908333 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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