Amino acid dipepetide frequency for Guillardia theta (strain CCMP2712) (Cryptophyte)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.162AlaAla: 8.162 ± 0.07	1.797AlaCys: 1.797 ± 0.021	3.822AlaAsp: 3.822 ± 0.022	5.417AlaGlu: 5.417 ± 0.041	2.657AlaPhe: 2.657 ± 0.019	5.92AlaGly: 5.92 ± 0.041	1.533AlaHis: 1.533 ± 0.014	3.557AlaIle: 3.557 ± 0.022	4.016AlaLys: 4.016 ± 0.028	7.182AlaLeu: 7.182 ± 0.039	2.417AlaMet: 2.417 ± 0.02	2.52AlaAsn: 2.52 ± 0.02	3.193AlaPro: 3.193 ± 0.032	3.017AlaGln: 3.017 ± 0.02	4.986AlaArg: 4.986 ± 0.031	6.898AlaSer: 6.898 ± 0.035	3.536AlaThr: 3.536 ± 0.022	5.155AlaVal: 5.155 ± 0.031	0.96AlaTrp: 0.96 ± 0.012	1.63AlaTyr: 1.63 ± 0.015	0.0AlaXaa: 0.0 ± 0.0
Cys	1.294CysAla: 1.294 ± 0.016	0.543CysCys: 0.543 ± 0.01	1.018CysAsp: 1.018 ± 0.012	1.181CysGlu: 1.181 ± 0.015	0.831CysPhe: 0.831 ± 0.01	1.42CysGly: 1.42 ± 0.019	0.407CysHis: 0.407 ± 0.007	0.934CysIle: 0.934 ± 0.011	1.124CysLys: 1.124 ± 0.017	1.889CysLeu: 1.889 ± 0.018	0.551CysMet: 0.551 ± 0.008	0.747CysAsn: 0.747 ± 0.011	1.103CysPro: 1.103 ± 0.032	0.778CysGln: 0.778 ± 0.011	1.246CysArg: 1.246 ± 0.013	1.976CysSer: 1.976 ± 0.024	1.006CysThr: 1.006 ± 0.015	1.252CysVal: 1.252 ± 0.014	0.297CysTrp: 0.297 ± 0.006	0.503CysTyr: 0.503 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.23AspAla: 4.23 ± 0.023	1.058AspCys: 1.058 ± 0.015	3.678AspAsp: 3.678 ± 0.048	4.671AspGlu: 4.671 ± 0.029	2.161AspPhe: 2.161 ± 0.016	4.259AspGly: 4.259 ± 0.025	1.05AspHis: 1.05 ± 0.011	2.477AspIle: 2.477 ± 0.017	2.973AspLys: 2.973 ± 0.024	5.132AspLeu: 5.132 ± 0.026	1.532AspMet: 1.532 ± 0.013	1.668AspAsn: 1.668 ± 0.014	2.573AspPro: 2.573 ± 0.017	1.911AspGln: 1.911 ± 0.016	2.967AspArg: 2.967 ± 0.021	4.018AspSer: 4.018 ± 0.022	2.103AspThr: 2.103 ± 0.016	4.052AspVal: 4.052 ± 0.023	0.763AspTrp: 0.763 ± 0.009	1.281AspTyr: 1.281 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	6.152GluAla: 6.152 ± 0.047	1.025GluCys: 1.025 ± 0.014	4.786GluAsp: 4.786 ± 0.035	9.645GluGlu: 9.645 ± 0.093	2.068GluPhe: 2.068 ± 0.016	5.192GluGly: 5.192 ± 0.031	1.617GluHis: 1.617 ± 0.018	3.358GluIle: 3.358 ± 0.019	4.539GluLys: 4.539 ± 0.04	6.6GluLeu: 6.6 ± 0.04	2.062GluMet: 2.062 ± 0.02	2.383GluAsn: 2.383 ± 0.019	2.04GluPro: 2.04 ± 0.017	3.593GluGln: 3.593 ± 0.036	4.806GluArg: 4.806 ± 0.036	4.673GluSer: 4.673 ± 0.025	3.251GluThr: 3.251 ± 0.023	4.723GluVal: 4.723 ± 0.026	0.897GluTrp: 0.897 ± 0.011	1.523GluTyr: 1.523 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	2.729PheAla: 2.729 ± 0.02	0.843PheCys: 0.843 ± 0.01	2.3PheAsp: 2.3 ± 0.018	2.282PheGlu: 2.282 ± 0.017	1.713PhePhe: 1.713 ± 0.018	2.404PheGly: 2.404 ± 0.019	0.957PheHis: 0.957 ± 0.01	1.576PheIle: 1.576 ± 0.014	1.699PheLys: 1.699 ± 0.014	3.968PheLeu: 3.968 ± 0.026	0.881PheMet: 0.881 ± 0.011	1.343PheAsn: 1.343 ± 0.015	1.701PhePro: 1.701 ± 0.016	1.559PheGln: 1.559 ± 0.015	1.977PheArg: 1.977 ± 0.015	3.344PheSer: 3.344 ± 0.025	1.805PheThr: 1.805 ± 0.019	2.612PheVal: 2.612 ± 0.018	0.47PheTrp: 0.47 ± 0.006	1.047PheTyr: 1.047 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	4.937GlyAla: 4.937 ± 0.037	1.317GlyCys: 1.317 ± 0.015	3.577GlyAsp: 3.577 ± 0.022	4.727GlyGlu: 4.727 ± 0.03	2.429GlyPhe: 2.429 ± 0.02	6.365GlyGly: 6.365 ± 0.047	1.396GlyHis: 1.396 ± 0.016	3.03GlyIle: 3.03 ± 0.021	4.04GlyLys: 4.04 ± 0.028	5.279GlyLeu: 5.279 ± 0.031	1.998GlyMet: 1.998 ± 0.018	2.478GlyAsn: 2.478 ± 0.022	2.249GlyPro: 2.249 ± 0.019	2.562GlyGln: 2.562 ± 0.021	4.445GlyArg: 4.445 ± 0.034	5.996GlySer: 5.996 ± 0.038	3.221GlyThr: 3.221 ± 0.023	4.045GlyVal: 4.045 ± 0.025	1.047GlyTrp: 1.047 ± 0.012	1.796GlyTyr: 1.796 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	1.879HisAla: 1.879 ± 0.015	0.443HisCys: 0.443 ± 0.008	1.237HisAsp: 1.237 ± 0.012	1.512HisGlu: 1.512 ± 0.014	0.878HisPhe: 0.878 ± 0.009	1.698HisGly: 1.698 ± 0.018	0.679HisHis: 0.679 ± 0.011	0.883HisIle: 0.883 ± 0.011	1.044HisLys: 1.044 ± 0.012	2.177HisLeu: 2.177 ± 0.018	0.536HisMet: 0.536 ± 0.008	0.729HisAsn: 0.729 ± 0.009	1.213HisPro: 1.213 ± 0.012	0.907HisGln: 0.907 ± 0.014	1.391HisArg: 1.391 ± 0.012	1.626HisSer: 1.626 ± 0.015	0.904HisThr: 0.904 ± 0.011	1.773HisVal: 1.773 ± 0.014	0.297HisTrp: 0.297 ± 0.006	0.536HisTyr: 0.536 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	3.649IleAla: 3.649 ± 0.023	1.014IleCys: 1.014 ± 0.014	2.508IleAsp: 2.508 ± 0.022	2.998IleGlu: 2.998 ± 0.022	1.941IlePhe: 1.941 ± 0.016	2.532IleGly: 2.532 ± 0.016	0.996IleHis: 0.996 ± 0.011	1.974IleIle: 1.974 ± 0.02	2.226IleLys: 2.226 ± 0.019	4.389IleLeu: 4.389 ± 0.026	1.045IleMet: 1.045 ± 0.011	1.526IleAsn: 1.526 ± 0.018	2.207IlePro: 2.207 ± 0.019	1.883IleGln: 1.883 ± 0.016	2.635IleArg: 2.635 ± 0.017	4.056IleSer: 4.056 ± 0.026	2.096IleThr: 2.096 ± 0.022	3.11IleVal: 3.11 ± 0.023	0.497IleTrp: 0.497 ± 0.007	1.08IleTyr: 1.08 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	4.152LysAla: 4.152 ± 0.031	0.79LysCys: 0.79 ± 0.01	3.134LysAsp: 3.134 ± 0.024	5.054LysGlu: 5.054 ± 0.039	1.866LysPhe: 1.866 ± 0.016	3.194LysGly: 3.194 ± 0.025	1.265LysHis: 1.265 ± 0.014	2.699LysIle: 2.699 ± 0.019	4.051LysLys: 4.051 ± 0.033	5.241LysLeu: 5.241 ± 0.032	1.545LysMet: 1.545 ± 0.013	1.972LysAsn: 1.972 ± 0.016	2.008LysPro: 2.008 ± 0.016	2.547LysGln: 2.547 ± 0.022	3.534LysArg: 3.534 ± 0.025	4.01LysSer: 4.01 ± 0.024	2.708LysThr: 2.708 ± 0.019	3.486LysVal: 3.486 ± 0.021	0.606LysTrp: 0.606 ± 0.008	1.35LysTyr: 1.35 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	7.166LeuAla: 7.166 ± 0.036	1.834LeuCys: 1.834 ± 0.016	5.035LeuAsp: 5.035 ± 0.026	6.699LeuGlu: 6.699 ± 0.038	3.429LeuPhe: 3.429 ± 0.021	5.302LeuGly: 5.302 ± 0.028	2.543LeuHis: 2.543 ± 0.019	3.632LeuIle: 3.632 ± 0.025	5.319LeuLys: 5.319 ± 0.033	10.28LeuLeu: 10.28 ± 0.058	2.204LeuMet: 2.204 ± 0.016	3.285LeuAsn: 3.285 ± 0.022	4.722LeuPro: 4.722 ± 0.031	5.051LeuGln: 5.051 ± 0.028	6.514LeuArg: 6.514 ± 0.033	8.372LeuSer: 8.372 ± 0.042	4.484LeuThr: 4.484 ± 0.03	6.204LeuVal: 6.204 ± 0.033	1.124LeuTrp: 1.124 ± 0.011	2.225LeuTyr: 2.225 ± 0.017	0.0LeuXaa: 0.0 ± 0.0
Met	2.114MetAla: 2.114 ± 0.016	0.436MetCys: 0.436 ± 0.008	1.336MetAsp: 1.336 ± 0.012	2.125MetGlu: 2.125 ± 0.018	0.912MetPhe: 0.912 ± 0.009	1.495MetGly: 1.495 ± 0.014	0.621MetHis: 0.621 ± 0.009	1.217MetIle: 1.217 ± 0.013	1.765MetLys: 1.765 ± 0.016	2.699MetLeu: 2.699 ± 0.017	1.001MetMet: 1.001 ± 0.021	0.985MetAsn: 0.985 ± 0.01	1.149MetPro: 1.149 ± 0.012	1.507MetGln: 1.507 ± 0.013	1.824MetArg: 1.824 ± 0.015	2.211MetSer: 2.211 ± 0.014	1.337MetThr: 1.337 ± 0.012	1.561MetVal: 1.561 ± 0.012	0.318MetTrp: 0.318 ± 0.006	0.649MetTyr: 0.649 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.65AsnAla: 2.65 ± 0.021	0.636AsnCys: 0.636 ± 0.011	1.835AsnAsp: 1.835 ± 0.017	2.309AsnGlu: 2.309 ± 0.018	1.589AsnPhe: 1.589 ± 0.015	2.402AsnGly: 2.402 ± 0.021	0.755AsnHis: 0.755 ± 0.009	1.758AsnIle: 1.758 ± 0.016	1.887AsnLys: 1.887 ± 0.016	3.564AsnLeu: 3.564 ± 0.028	0.962AsnMet: 0.962 ± 0.01	1.38AsnAsn: 1.38 ± 0.022	1.769AsnPro: 1.769 ± 0.018	1.461AsnGln: 1.461 ± 0.013	1.826AsnArg: 1.826 ± 0.015	2.801AsnSer: 2.801 ± 0.022	1.546AsnThr: 1.546 ± 0.015	2.604AsnVal: 2.604 ± 0.022	0.386AsnTrp: 0.386 ± 0.007	0.844AsnTyr: 0.844 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	3.851ProAla: 3.851 ± 0.033	0.93ProCys: 0.93 ± 0.017	2.31ProAsp: 2.31 ± 0.018	2.712ProGlu: 2.712 ± 0.018	1.604ProPhe: 1.604 ± 0.013	2.851ProGly: 2.851 ± 0.027	1.013ProHis: 1.013 ± 0.013	1.659ProIle: 1.659 ± 0.014	1.925ProLys: 1.925 ± 0.016	3.845ProLeu: 3.845 ± 0.026	0.964ProMet: 0.964 ± 0.011	1.47ProAsn: 1.47 ± 0.014	3.238ProPro: 3.238 ± 0.038	1.81ProGln: 1.81 ± 0.016	2.518ProArg: 2.518 ± 0.018	4.7ProSer: 4.7 ± 0.035	2.223ProThr: 2.223 ± 0.017	2.853ProVal: 2.853 ± 0.022	0.613ProTrp: 0.613 ± 0.009	1.056ProTyr: 1.056 ± 0.012	0.0ProXaa: 0.0 ± 0.0
Gln	3.539GlnAla: 3.539 ± 0.023	0.688GlnCys: 0.688 ± 0.012	2.508GlnAsp: 2.508 ± 0.018	3.961GlnGlu: 3.961 ± 0.034	1.197GlnPhe: 1.197 ± 0.013	2.977GlnGly: 2.977 ± 0.021	1.122GlnHis: 1.122 ± 0.015	1.813GlnIle: 1.813 ± 0.016	2.112GlnLys: 2.112 ± 0.019	4.139GlnLeu: 4.139 ± 0.024	1.026GlnMet: 1.026 ± 0.011	1.429GlnAsn: 1.429 ± 0.013	1.801GlnPro: 1.801 ± 0.018	3.03GlnGln: 3.03 ± 0.058	2.803GlnArg: 2.803 ± 0.02	3.099GlnSer: 3.099 ± 0.021	2.114GlnThr: 2.114 ± 0.016	3.025GlnVal: 3.025 ± 0.024	0.486GlnTrp: 0.486 ± 0.007	0.976GlnTyr: 0.976 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.755ArgAla: 4.755 ± 0.032	1.194ArgCys: 1.194 ± 0.014	3.141ArgAsp: 3.141 ± 0.021	4.758ArgGlu: 4.758 ± 0.034	2.128ArgPhe: 2.128 ± 0.017	4.003ArgGly: 4.003 ± 0.028	1.403ArgHis: 1.403 ± 0.015	2.858ArgIle: 2.858 ± 0.021	3.826ArgLys: 3.826 ± 0.029	5.775ArgLeu: 5.775 ± 0.03	1.985ArgMet: 1.985 ± 0.017	2.244ArgAsn: 2.244 ± 0.016	2.412ArgPro: 2.412 ± 0.017	2.734ArgGln: 2.734 ± 0.021	5.414ArgArg: 5.414 ± 0.043	5.354ArgSer: 5.354 ± 0.03	2.849ArgThr: 2.849 ± 0.019	3.887ArgVal: 3.887 ± 0.022	0.973ArgTrp: 0.973 ± 0.011	1.505ArgTyr: 1.505 ± 0.014	0.0ArgXaa: 0.0 ± 0.0
Ser	6.069SerAla: 6.069 ± 0.028	2.024SerCys: 2.024 ± 0.02	4.255SerAsp: 4.255 ± 0.024	4.898SerGlu: 4.898 ± 0.027	3.802SerPhe: 3.802 ± 0.029	5.141SerGly: 5.141 ± 0.031	1.81SerHis: 1.81 ± 0.015	3.975SerIle: 3.975 ± 0.03	4.557SerLys: 4.557 ± 0.024	8.746SerLeu: 8.746 ± 0.042	2.388SerMet: 2.388 ± 0.017	3.131SerAsn: 3.131 ± 0.026	4.189SerPro: 4.189 ± 0.029	3.422SerGln: 3.422 ± 0.024	5.139SerArg: 5.139 ± 0.03	10.959SerSer: 10.959 ± 0.074	4.351SerThr: 4.351 ± 0.033	5.024SerVal: 5.024 ± 0.032	1.285SerTrp: 1.285 ± 0.011	2.042SerTyr: 2.042 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	3.728ThrAla: 3.728 ± 0.024	1.31ThrCys: 1.31 ± 0.02	2.167ThrAsp: 2.167 ± 0.017	2.681ThrGlu: 2.681 ± 0.02	2.045ThrPhe: 2.045 ± 0.02	3.273ThrGly: 3.273 ± 0.029	0.86ThrHis: 0.86 ± 0.01	2.39ThrIle: 2.39 ± 0.021	2.163ThrLys: 2.163 ± 0.017	4.482ThrLeu: 4.482 ± 0.029	1.288ThrMet: 1.288 ± 0.011	1.594ThrAsn: 1.594 ± 0.016	2.294ThrPro: 2.294 ± 0.019	1.595ThrGln: 1.595 ± 0.014	2.83ThrArg: 2.83 ± 0.019	4.782ThrSer: 4.782 ± 0.033	2.46ThrThr: 2.46 ± 0.026	3.229ThrVal: 3.229 ± 0.029	0.737ThrTrp: 0.737 ± 0.011	1.207ThrTyr: 1.207 ± 0.013	0.0ThrXaa: 0.0 ± 0.0
Val	4.915ValAla: 4.915 ± 0.027	1.463ValCys: 1.463 ± 0.015	3.687ValAsp: 3.687 ± 0.021	4.895ValGlu: 4.895 ± 0.026	2.409ValPhe: 2.409 ± 0.019	4.089ValGly: 4.089 ± 0.021	1.443ValHis: 1.443 ± 0.012	2.802ValIle: 2.802 ± 0.022	3.784ValLys: 3.784 ± 0.023	6.505ValLeu: 6.505 ± 0.034	1.769ValMet: 1.769 ± 0.016	2.388ValAsn: 2.388 ± 0.024	2.818ValPro: 2.818 ± 0.021	2.9ValGln: 2.9 ± 0.022	3.958ValArg: 3.958 ± 0.021	5.329ValSer: 5.329 ± 0.033	3.222ValThr: 3.222 ± 0.025	4.754ValVal: 4.754 ± 0.031	0.891ValTrp: 0.891 ± 0.01	1.636ValTyr: 1.636 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	0.802TrpAla: 0.802 ± 0.011	0.226TrpCys: 0.226 ± 0.005	0.766TrpAsp: 0.766 ± 0.009	0.886TrpGlu: 0.886 ± 0.01	0.476TrpPhe: 0.476 ± 0.007	0.774TrpGly: 0.774 ± 0.009	0.282TrpHis: 0.282 ± 0.005	0.658TrpIle: 0.658 ± 0.008	0.911TrpLys: 0.911 ± 0.01	1.191TrpLeu: 1.191 ± 0.014	0.454TrpMet: 0.454 ± 0.007	0.643TrpAsn: 0.643 ± 0.009	0.463TrpPro: 0.463 ± 0.007	0.567TrpGln: 0.567 ± 0.008	0.971TrpArg: 0.971 ± 0.013	1.096TrpSer: 1.096 ± 0.012	0.738TrpThr: 0.738 ± 0.011	0.713TrpVal: 0.713 ± 0.01	0.214TrpTrp: 0.214 ± 0.005	0.359TrpTyr: 0.359 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.602TyrAla: 1.602 ± 0.014	0.528TyrCys: 0.528 ± 0.014	1.459TyrAsp: 1.459 ± 0.012	1.519TyrGlu: 1.519 ± 0.014	1.077TyrPhe: 1.077 ± 0.013	1.641TyrGly: 1.641 ± 0.014	0.591TyrHis: 0.591 ± 0.009	1.112TyrIle: 1.112 ± 0.012	1.254TyrLys: 1.254 ± 0.014	2.34TyrLeu: 2.34 ± 0.019	0.653TyrMet: 0.653 ± 0.009	1.049TyrAsn: 1.049 ± 0.014	1.001TyrPro: 1.001 ± 0.012	1.012TyrGln: 1.012 ± 0.011	1.413TyrArg: 1.413 ± 0.015	1.909TyrSer: 1.909 ± 0.019	1.162TyrThr: 1.162 ± 0.013	1.595TyrVal: 1.595 ± 0.015	0.329TyrTrp: 0.329 ± 0.007	0.726TyrTyr: 0.726 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 24590 proteins (10138161 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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