Amino acid dipepetide frequency for Tomato mosaic Trujillo virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.647AlaAla: 2.647 ± 2.018
0.662AlaCys: 0.662 ± 0.574
1.324AlaAsp: 1.324 ± 0.58
3.309AlaGlu: 3.309 ± 1.15
1.324AlaPhe: 1.324 ± 0.807
1.985AlaGly: 1.985 ± 1.094
1.324AlaHis: 1.324 ± 0.801
2.647AlaIle: 2.647 ± 1.265
3.309AlaLys: 3.309 ± 1.09
3.309AlaLeu: 3.309 ± 0.989
1.324AlaMet: 1.324 ± 0.629
1.324AlaAsn: 1.324 ± 0.629
3.971AlaPro: 3.971 ± 1.507
1.324AlaGln: 1.324 ± 0.58
5.956AlaArg: 5.956 ± 1.959
9.927AlaSer: 9.927 ± 2.484
2.647AlaThr: 2.647 ± 1.218
1.985AlaVal: 1.985 ± 1.023
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.324CysAla: 1.324 ± 0.58
0.0CysCys: 0.0 ± 0.0
0.662CysAsp: 0.662 ± 0.601
0.662CysGlu: 0.662 ± 0.574
0.0CysPhe: 0.0 ± 0.0
0.662CysGly: 0.662 ± 0.677
0.0CysHis: 0.0 ± 0.0
1.324CysIle: 1.324 ± 0.775
1.324CysLys: 1.324 ± 0.629
0.0CysLeu: 0.0 ± 0.0
0.662CysMet: 0.662 ± 0.601
1.985CysAsn: 1.985 ± 0.687
0.662CysPro: 0.662 ± 0.735
0.0CysGln: 0.0 ± 0.0
1.324CysArg: 1.324 ± 0.58
3.971CysSer: 3.971 ± 2.615
2.647CysThr: 2.647 ± 1.48
1.324CysVal: 1.324 ± 0.775
1.324CysTrp: 1.324 ± 1.292
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.324AspAla: 1.324 ± 0.629
1.985AspCys: 1.985 ± 1.704
3.309AspAsp: 3.309 ± 1.509
2.647AspGlu: 2.647 ± 0.565
1.985AspPhe: 1.985 ± 0.623
1.324AspGly: 1.324 ± 1.009
1.324AspHis: 1.324 ± 0.807
1.985AspIle: 1.985 ± 0.898
1.324AspLys: 1.324 ± 1.202
6.618AspLeu: 6.618 ± 1.571
1.324AspMet: 1.324 ± 0.696
1.985AspAsn: 1.985 ± 0.623
2.647AspPro: 2.647 ± 1.31
0.662AspGln: 0.662 ± 0.66
5.295AspArg: 5.295 ± 1.648
3.309AspSer: 3.309 ± 1.254
3.309AspThr: 3.309 ± 1.06
5.295AspVal: 5.295 ± 0.897
1.324AspTrp: 1.324 ± 0.696
1.985AspTyr: 1.985 ± 0.687
0.0AspXaa: 0.0 ± 0.0
Glu
4.633GluAla: 4.633 ± 1.757
0.662GluCys: 0.662 ± 0.601
1.985GluAsp: 1.985 ± 1.407
2.647GluGlu: 2.647 ± 2.018
0.0GluPhe: 0.0 ± 0.0
4.633GluGly: 4.633 ± 1.849
0.0GluHis: 0.0 ± 0.0
2.647GluIle: 2.647 ± 1.803
2.647GluLys: 2.647 ± 1.466
4.633GluLeu: 4.633 ± 1.327
0.662GluMet: 0.662 ± 0.505
5.295GluAsn: 5.295 ± 1.519
2.647GluPro: 2.647 ± 1.133
1.985GluGln: 1.985 ± 1.347
2.647GluArg: 2.647 ± 0.877
4.633GluSer: 4.633 ± 2.801
0.662GluThr: 0.662 ± 0.505
1.324GluVal: 1.324 ± 0.896
2.647GluTrp: 2.647 ± 1.172
1.324GluTyr: 1.324 ± 1.202
0.0GluXaa: 0.0 ± 0.0
Phe
1.324PheAla: 1.324 ± 0.807
0.662PheCys: 0.662 ± 0.574
1.985PheAsp: 1.985 ± 0.651
0.662PheGlu: 0.662 ± 0.505
0.662PhePhe: 0.662 ± 0.601
1.985PheGly: 1.985 ± 0.651
1.985PheHis: 1.985 ± 1.184
1.324PheIle: 1.324 ± 1.009
3.971PheLys: 3.971 ± 1.796
2.647PheLeu: 2.647 ± 1.644
0.662PheMet: 0.662 ± 0.505
2.647PheAsn: 2.647 ± 0.718
1.324PhePro: 1.324 ± 1.202
2.647PheGln: 2.647 ± 1.369
2.647PheArg: 2.647 ± 1.391
3.309PheSer: 3.309 ± 1.509
2.647PheThr: 2.647 ± 0.623
1.324PheVal: 1.324 ± 1.292
1.985PheTrp: 1.985 ± 1.347
1.324PheTyr: 1.324 ± 1.149
0.0PheXaa: 0.0 ± 0.0
Gly
3.971GlyAla: 3.971 ± 1.7
1.985GlyCys: 1.985 ± 1.267
1.324GlyAsp: 1.324 ± 0.822
3.971GlyGlu: 3.971 ± 1.17
1.324GlyPhe: 1.324 ± 0.898
5.956GlyGly: 5.956 ± 1.651
1.324GlyHis: 1.324 ± 0.741
1.324GlyIle: 1.324 ± 0.629
5.956GlyLys: 5.956 ± 2.38
2.647GlyLeu: 2.647 ± 0.877
0.662GlyMet: 0.662 ± 0.618
2.647GlyAsn: 2.647 ± 1.271
1.985GlyPro: 1.985 ± 1.225
3.309GlyGln: 3.309 ± 1.22
3.309GlyArg: 3.309 ± 0.805
6.618GlySer: 6.618 ± 2.214
5.956GlyThr: 5.956 ± 0.95
5.956GlyVal: 5.956 ± 2.282
0.0GlyTrp: 0.0 ± 0.0
0.662GlyTyr: 0.662 ± 0.505
0.0GlyXaa: 0.0 ± 0.0
His
1.985HisAla: 1.985 ± 0.623
1.324HisCys: 1.324 ± 0.741
2.647HisAsp: 2.647 ± 1.272
0.662HisGlu: 0.662 ± 0.646
1.324HisPhe: 1.324 ± 0.58
2.647HisGly: 2.647 ± 1.873
0.662HisHis: 0.662 ± 0.677
0.662HisIle: 0.662 ± 0.677
1.324HisLys: 1.324 ± 0.782
4.633HisLeu: 4.633 ± 1.35
0.0HisMet: 0.0 ± 0.0
1.985HisAsn: 1.985 ± 0.901
1.324HisPro: 1.324 ± 0.58
1.985HisGln: 1.985 ± 0.898
2.647HisArg: 2.647 ± 1.389
3.309HisSer: 3.309 ± 1.103
1.324HisThr: 1.324 ± 1.149
3.309HisVal: 3.309 ± 1.036
0.662HisTrp: 0.662 ± 0.505
1.324HisTyr: 1.324 ± 0.827
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.662IleCys: 0.662 ± 0.505
4.633IleAsp: 4.633 ± 1.904
4.633IleGlu: 4.633 ± 2.195
0.662IlePhe: 0.662 ± 0.505
1.985IleGly: 1.985 ± 1.293
2.647IleHis: 2.647 ± 1.248
1.985IleIle: 1.985 ± 0.82
6.618IleLys: 6.618 ± 2.768
1.324IleLeu: 1.324 ± 0.775
0.662IleMet: 0.662 ± 0.574
1.985IleAsn: 1.985 ± 1.293
3.971IlePro: 3.971 ± 1.94
1.324IleGln: 1.324 ± 1.009
5.956IleArg: 5.956 ± 2.144
4.633IleSer: 4.633 ± 1.714
3.309IleThr: 3.309 ± 0.59
2.647IleVal: 2.647 ± 1.05
1.985IleTrp: 1.985 ± 1.004
2.647IleTyr: 2.647 ± 1.412
0.0IleXaa: 0.0 ± 0.0
Lys
2.647LysAla: 2.647 ± 1.369
0.0LysCys: 0.0 ± 0.0
5.956LysAsp: 5.956 ± 2.055
3.309LysGlu: 3.309 ± 2.523
3.971LysPhe: 3.971 ± 1.265
3.309LysGly: 3.309 ± 0.938
1.324LysHis: 1.324 ± 0.58
5.956LysIle: 5.956 ± 1.082
1.324LysLys: 1.324 ± 0.822
3.971LysLeu: 3.971 ± 1.51
0.662LysMet: 0.662 ± 0.646
3.971LysAsn: 3.971 ± 1.514
3.309LysPro: 3.309 ± 1.042
0.662LysGln: 0.662 ± 0.601
5.956LysArg: 5.956 ± 1.746
3.971LysSer: 3.971 ± 1.258
0.662LysThr: 0.662 ± 0.735
5.956LysVal: 5.956 ± 3.228
0.0LysTrp: 0.0 ± 0.0
1.324LysTyr: 1.324 ± 0.629
0.0LysXaa: 0.0 ± 0.0
Leu
0.662LeuAla: 0.662 ± 0.66
0.662LeuCys: 0.662 ± 0.505
5.956LeuAsp: 5.956 ± 2.283
1.324LeuGlu: 1.324 ± 0.871
3.309LeuPhe: 3.309 ± 1.509
3.971LeuGly: 3.971 ± 0.578
3.971LeuHis: 3.971 ± 1.572
1.985LeuIle: 1.985 ± 1.023
3.971LeuLys: 3.971 ± 1.165
3.309LeuLeu: 3.309 ± 1.105
0.662LeuMet: 0.662 ± 0.646
5.295LeuAsn: 5.295 ± 1.605
2.647LeuPro: 2.647 ± 1.48
3.971LeuGln: 3.971 ± 1.534
3.971LeuArg: 3.971 ± 0.838
8.604LeuSer: 8.604 ± 2.879
3.309LeuThr: 3.309 ± 1.27
4.633LeuVal: 4.633 ± 1.18
0.0LeuTrp: 0.0 ± 0.0
3.309LeuTyr: 3.309 ± 1.231
0.0LeuXaa: 0.0 ± 0.0
Met
1.324MetAla: 1.324 ± 0.737
1.324MetCys: 1.324 ± 0.929
2.647MetAsp: 2.647 ± 1.218
0.0MetGlu: 0.0 ± 0.0
1.324MetPhe: 1.324 ± 1.149
1.324MetGly: 1.324 ± 0.896
0.662MetHis: 0.662 ± 0.574
0.0MetIle: 0.0 ± 0.0
2.647MetLys: 2.647 ± 0.877
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.324MetAsn: 1.324 ± 0.737
1.985MetPro: 1.985 ± 1.094
1.324MetGln: 1.324 ± 0.871
0.662MetArg: 0.662 ± 0.677
2.647MetSer: 2.647 ± 1.653
1.324MetThr: 1.324 ± 0.807
0.662MetVal: 0.662 ± 0.646
0.0MetTrp: 0.0 ± 0.0
2.647MetTyr: 2.647 ± 1.333
0.0MetXaa: 0.0 ± 0.0
Asn
5.295AsnAla: 5.295 ± 1.169
2.647AsnCys: 2.647 ± 0.877
1.324AsnAsp: 1.324 ± 0.629
3.309AsnGlu: 3.309 ± 2.008
1.324AsnPhe: 1.324 ± 0.868
3.309AsnGly: 3.309 ± 0.837
3.971AsnHis: 3.971 ± 2.407
3.309AsnIle: 3.309 ± 0.969
2.647AsnLys: 2.647 ± 1.466
3.971AsnLeu: 3.971 ± 1.747
1.985AsnMet: 1.985 ± 1.152
1.985AsnAsn: 1.985 ± 0.852
3.309AsnPro: 3.309 ± 0.88
0.662AsnGln: 0.662 ± 0.646
4.633AsnArg: 4.633 ± 2.155
4.633AsnSer: 4.633 ± 1.968
0.662AsnThr: 0.662 ± 0.505
3.971AsnVal: 3.971 ± 1.275
0.662AsnTrp: 0.662 ± 0.505
1.985AsnTyr: 1.985 ± 0.623
0.0AsnXaa: 0.0 ± 0.0
Pro
0.662ProAla: 0.662 ± 0.735
0.662ProCys: 0.662 ± 0.574
1.985ProAsp: 1.985 ± 0.651
2.647ProGlu: 2.647 ± 1.624
1.324ProPhe: 1.324 ± 0.58
3.971ProGly: 3.971 ± 1.174
1.985ProHis: 1.985 ± 0.687
4.633ProIle: 4.633 ± 2.801
3.309ProLys: 3.309 ± 1.471
3.309ProLeu: 3.309 ± 1.517
1.324ProMet: 1.324 ± 1.149
1.324ProAsn: 1.324 ± 0.871
3.309ProPro: 3.309 ± 1.704
4.633ProGln: 4.633 ± 2.573
3.309ProArg: 3.309 ± 1.772
7.28ProSer: 7.28 ± 2.255
3.971ProThr: 3.971 ± 1.439
2.647ProVal: 2.647 ± 1.434
1.324ProTrp: 1.324 ± 0.775
1.324ProTyr: 1.324 ± 0.775
0.0ProXaa: 0.0 ± 0.0
Gln
3.309GlnAla: 3.309 ± 0.859
0.662GlnCys: 0.662 ± 0.505
1.324GlnAsp: 1.324 ± 0.822
5.295GlnGlu: 5.295 ± 1.958
1.985GlnPhe: 1.985 ± 1.068
2.647GlnGly: 2.647 ± 1.48
0.0GlnHis: 0.0 ± 0.0
1.985GlnIle: 1.985 ± 1.199
0.662GlnLys: 0.662 ± 0.505
3.971GlnLeu: 3.971 ± 2.183
1.324GlnMet: 1.324 ± 0.879
0.662GlnAsn: 0.662 ± 0.505
4.633GlnPro: 4.633 ± 2.516
1.324GlnGln: 1.324 ± 0.58
3.309GlnArg: 3.309 ± 1.148
2.647GlnSer: 2.647 ± 1.172
1.324GlnThr: 1.324 ± 0.696
1.985GlnVal: 1.985 ± 0.859
0.0GlnTrp: 0.0 ± 0.0
3.309GlnTyr: 3.309 ± 1.008
0.0GlnXaa: 0.0 ± 0.0
Arg
5.295ArgAla: 5.295 ± 2.046
1.324ArgCys: 1.324 ± 1.202
3.309ArgAsp: 3.309 ± 1.865
2.647ArgGlu: 2.647 ± 1.128
3.971ArgPhe: 3.971 ± 2.007
6.618ArgGly: 6.618 ± 1.314
4.633ArgHis: 4.633 ± 1.681
4.633ArgIle: 4.633 ± 1.382
3.971ArgLys: 3.971 ± 0.812
2.647ArgLeu: 2.647 ± 1.087
1.324ArgMet: 1.324 ± 0.98
2.647ArgAsn: 2.647 ± 1.133
5.956ArgPro: 5.956 ± 0.869
1.324ArgGln: 1.324 ± 0.741
7.28ArgArg: 7.28 ± 3.563
7.28ArgSer: 7.28 ± 1.444
4.633ArgThr: 4.633 ± 1.643
3.971ArgVal: 3.971 ± 1.123
0.662ArgTrp: 0.662 ± 0.601
1.985ArgTyr: 1.985 ± 1.262
0.0ArgXaa: 0.0 ± 0.0
Ser
2.647SerAla: 2.647 ± 1.087
2.647SerCys: 2.647 ± 0.877
2.647SerAsp: 2.647 ± 1.133
1.985SerGlu: 1.985 ± 1.263
2.647SerPhe: 2.647 ± 0.967
3.309SerGly: 3.309 ± 1.258
4.633SerHis: 4.633 ± 1.69
6.618SerIle: 6.618 ± 2.049
4.633SerLys: 4.633 ± 0.925
7.28SerLeu: 7.28 ± 1.536
3.309SerMet: 3.309 ± 1.435
8.604SerAsn: 8.604 ± 2.338
5.295SerPro: 5.295 ± 2.668
3.971SerGln: 3.971 ± 1.472
8.604SerArg: 8.604 ± 2.232
5.956SerSer: 5.956 ± 2.343
6.618SerThr: 6.618 ± 2.21
5.295SerVal: 5.295 ± 1.566
1.985SerTrp: 1.985 ± 1.068
3.309SerTyr: 3.309 ± 0.989
0.0SerXaa: 0.0 ± 0.0
Thr
7.28ThrAla: 7.28 ± 2.224
0.0ThrCys: 0.0 ± 0.0
1.985ThrAsp: 1.985 ± 1.167
1.324ThrGlu: 1.324 ± 0.775
2.647ThrPhe: 2.647 ± 1.957
3.971ThrGly: 3.971 ± 1.426
3.309ThrHis: 3.309 ± 1.693
1.324ThrIle: 1.324 ± 0.58
0.662ThrLys: 0.662 ± 0.505
3.971ThrLeu: 3.971 ± 1.781
1.324ThrMet: 1.324 ± 0.827
2.647ThrAsn: 2.647 ± 0.827
2.647ThrPro: 2.647 ± 1.299
1.985ThrGln: 1.985 ± 1.218
1.985ThrArg: 1.985 ± 0.818
4.633ThrSer: 4.633 ± 1.986
2.647ThrThr: 2.647 ± 1.339
3.971ThrVal: 3.971 ± 1.634
0.0ThrTrp: 0.0 ± 0.0
4.633ThrTyr: 4.633 ± 1.826
0.0ThrXaa: 0.0 ± 0.0
Val
1.985ValAla: 1.985 ± 0.82
0.662ValCys: 0.662 ± 0.601
4.633ValAsp: 4.633 ± 1.788
4.633ValGlu: 4.633 ± 1.898
3.309ValPhe: 3.309 ± 1.685
2.647ValGly: 2.647 ± 1.048
1.324ValHis: 1.324 ± 0.58
4.633ValIle: 4.633 ± 2.292
3.971ValLys: 3.971 ± 1.412
3.309ValLeu: 3.309 ± 1.27
2.647ValMet: 2.647 ± 1.666
5.956ValAsn: 5.956 ± 1.469
1.985ValPro: 1.985 ± 0.623
5.956ValGln: 5.956 ± 1.738
1.985ValArg: 1.985 ± 0.859
1.985ValSer: 1.985 ± 0.986
1.985ValThr: 1.985 ± 1.153
4.633ValVal: 4.633 ± 3.759
0.662ValTrp: 0.662 ± 0.66
5.295ValTyr: 5.295 ± 1.576
0.0ValXaa: 0.0 ± 0.0
Trp
1.324TrpAla: 1.324 ± 0.58
0.662TrpCys: 0.662 ± 0.735
0.0TrpAsp: 0.0 ± 0.0
1.324TrpGlu: 1.324 ± 0.807
0.0TrpPhe: 0.0 ± 0.0
0.662TrpGly: 0.662 ± 0.505
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.647TrpLys: 2.647 ± 0.565
0.662TrpLeu: 0.662 ± 0.574
1.324TrpMet: 1.324 ± 0.737
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.662TrpGln: 0.662 ± 0.505
1.324TrpArg: 1.324 ± 0.898
0.662TrpSer: 0.662 ± 0.646
2.647TrpThr: 2.647 ± 1.046
1.324TrpVal: 1.324 ± 0.898
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.662TyrAla: 0.662 ± 0.574
0.662TyrCys: 0.662 ± 0.646
1.324TyrAsp: 1.324 ± 0.737
1.324TyrGlu: 1.324 ± 1.149
4.633TyrPhe: 4.633 ± 0.631
3.971TyrGly: 3.971 ± 1.179
0.662TyrHis: 0.662 ± 0.505
5.295TyrIle: 5.295 ± 2.256
1.324TyrLys: 1.324 ± 0.826
3.309TyrLeu: 3.309 ± 1.794
1.324TyrMet: 1.324 ± 0.8
1.324TyrAsn: 1.324 ± 0.737
1.324TyrPro: 1.324 ± 0.696
2.647TyrGln: 2.647 ± 0.827
3.971TyrArg: 3.971 ± 2.063
1.985TyrSer: 1.985 ± 0.852
0.662TyrThr: 0.662 ± 0.66
1.985TyrVal: 1.985 ± 1.199
0.0TyrTrp: 0.0 ± 0.0
2.647TyrTyr: 2.647 ± 1.957
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1512 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski