Phocoena phocoena papillomavirus 4

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Dyopipapillomavirus; Dyopipapillomavirus 1

Average proteome isoelectric point is 6.58

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|F2VIS2|F2VIS2_9PAPI Regulatory protein E2 OS=Phocoena phocoena papillomavirus 4 OX=706527 GN=E2 PE=3 SV=1
MM1 pKa = 8.15DD2 pKa = 5.89PPQGTDD8 pKa = 3.02GDD10 pKa = 4.34EE11 pKa = 4.89GCSGWCFVDD20 pKa = 6.23LEE22 pKa = 4.2AQEE25 pKa = 5.81DD26 pKa = 4.67GVDD29 pKa = 5.04DD30 pKa = 4.67NDD32 pKa = 4.38NDD34 pKa = 4.13DD35 pKa = 3.92EE36 pKa = 4.95SVDD39 pKa = 3.71EE40 pKa = 4.07EE41 pKa = 5.05DD42 pKa = 3.77YY43 pKa = 11.51AIVNLFDD50 pKa = 6.13DD51 pKa = 4.43EE52 pKa = 6.34DD53 pKa = 4.01VTQGNSLTVYY63 pKa = 9.31EE64 pKa = 4.38AQNRR68 pKa = 11.84ADD70 pKa = 4.87DD71 pKa = 3.73EE72 pKa = 4.51RR73 pKa = 11.84AVQKK77 pKa = 10.6LKK79 pKa = 10.9RR80 pKa = 11.84KK81 pKa = 9.15LLQSPEE87 pKa = 4.44LDD89 pKa = 3.15LSPRR93 pKa = 11.84LSAITIGKK101 pKa = 9.97KK102 pKa = 9.39SGKK105 pKa = 9.46AKK107 pKa = 10.15RR108 pKa = 11.84RR109 pKa = 11.84LFMPGQDD116 pKa = 2.89SGYY119 pKa = 8.6GQSVEE124 pKa = 4.32ANVEE128 pKa = 4.03EE129 pKa = 5.32SVLQTQVSLNFNGEE143 pKa = 3.96DD144 pKa = 3.4SGGGGGAPCTVSGAQEE160 pKa = 4.14TPEE163 pKa = 4.56TMIQLLKK170 pKa = 10.18QANPQAAMMGLFKK183 pKa = 10.26KK184 pKa = 9.36TMGISFTDD192 pKa = 3.91LSRR195 pKa = 11.84TFQSDD200 pKa = 3.17KK201 pKa = 10.33TPCVDD206 pKa = 3.14WVAVCFGVPLSLIDD220 pKa = 3.58ACTEE224 pKa = 3.77LLQPHH229 pKa = 6.63CEE231 pKa = 4.06FGNVTTTPCCTGYY244 pKa = 11.2LLLLLARR251 pKa = 11.84FQVAKK256 pKa = 10.66CRR258 pKa = 11.84VTVKK262 pKa = 10.69KK263 pKa = 10.85LLGNTLHH270 pKa = 7.23VPEE273 pKa = 4.24QQILTEE279 pKa = 4.19PPKK282 pKa = 10.33IRR284 pKa = 11.84CPAAAIYY291 pKa = 8.97WYY293 pKa = 10.25KK294 pKa = 10.89KK295 pKa = 10.39GITGVAKK302 pKa = 9.33TWGPLPEE309 pKa = 4.34WLAKK313 pKa = 8.54MVNVSSNLADD323 pKa = 3.25AAVFNLSDD331 pKa = 4.35MIQWAYY337 pKa = 11.19DD338 pKa = 3.45NNKK341 pKa = 8.75TEE343 pKa = 4.93DD344 pKa = 3.27ADD346 pKa = 3.39IAYY349 pKa = 9.74GYY351 pKa = 10.47AQLADD356 pKa = 3.43TDD358 pKa = 4.25RR359 pKa = 11.84NAEE362 pKa = 4.12AFLKK366 pKa = 10.95SNSQAKK372 pKa = 8.57YY373 pKa = 10.44VKK375 pKa = 10.13DD376 pKa = 3.53CGVMVRR382 pKa = 11.84LYY384 pKa = 10.73KK385 pKa = 10.13KK386 pKa = 10.81AEE388 pKa = 3.91MQRR391 pKa = 11.84TSMKK395 pKa = 10.27DD396 pKa = 2.91WIKK399 pKa = 10.62RR400 pKa = 11.84RR401 pKa = 11.84CEE403 pKa = 3.93EE404 pKa = 4.07VDD406 pKa = 3.84GDD408 pKa = 4.32GDD410 pKa = 3.39WRR412 pKa = 11.84PIVSFLKK419 pKa = 10.72FQGIDD424 pKa = 3.06MAVFISVLKK433 pKa = 10.77NFLKK437 pKa = 10.92GIPKK441 pKa = 9.61QNCIVICGPPNTGKK455 pKa = 10.6SLFSVSLIQFLSGKK469 pKa = 10.0VISFVNSKK477 pKa = 8.57SHH479 pKa = 7.02FWLQPLGEE487 pKa = 4.64CKK489 pKa = 10.17VALLDD494 pKa = 5.24DD495 pKa = 4.1ATGPAWDD502 pKa = 4.22YY503 pKa = 11.58FDD505 pKa = 3.62TFLRR509 pKa = 11.84NLVDD513 pKa = 4.08GNPISLDD520 pKa = 3.89CKK522 pKa = 10.46HH523 pKa = 6.62KK524 pKa = 11.09APTQVKK530 pKa = 9.21CPPLIITSNIDD541 pKa = 2.95VTASDD546 pKa = 3.02RR547 pKa = 11.84WKK549 pKa = 10.49YY550 pKa = 10.0LHH552 pKa = 7.01SRR554 pKa = 11.84LKK556 pKa = 11.04LFTFSNPCPLTEE568 pKa = 4.04QGEE571 pKa = 4.37PAFNLTPVNWKK582 pKa = 10.37CFFKK586 pKa = 10.76RR587 pKa = 11.84LKK589 pKa = 9.68TRR591 pKa = 11.84LGLADD596 pKa = 5.7DD597 pKa = 4.35EE598 pKa = 5.48GEE600 pKa = 4.18DD601 pKa = 4.1HH602 pKa = 7.37GEE604 pKa = 3.89SQQPLKK610 pKa = 10.17CTARR614 pKa = 11.84GTDD617 pKa = 3.33GFVV620 pKa = 2.77

Molecular weight:
68.62 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|F2VIS3|F2VIS3_9PAPI E4 protein (Fragment) OS=Phocoena phocoena papillomavirus 4 OX=706527 GN=E4 PE=4 SV=1
LL1 pKa = 6.64TLNLLLAQPIPRR13 pKa = 11.84PPRR16 pKa = 11.84VPVPRR21 pKa = 11.84SPYY24 pKa = 10.5LDD26 pKa = 3.72LLGHH30 pKa = 6.9IPRR33 pKa = 11.84TPPQQHH39 pKa = 6.67APPTCPRR46 pKa = 11.84LQRR49 pKa = 11.84RR50 pKa = 11.84GNPGRR55 pKa = 11.84QPLPRR60 pKa = 11.84ADD62 pKa = 3.81KK63 pKa = 11.0DD64 pKa = 4.06PIRR67 pKa = 11.84KK68 pKa = 9.29RR69 pKa = 11.84LWDD72 pKa = 3.77SDD74 pKa = 3.6DD75 pKa = 4.28SEE77 pKa = 4.57NKK79 pKa = 10.17EE80 pKa = 4.47NIPPLQQQGPYY91 pKa = 9.22TVDD94 pKa = 4.36FPPIGPLDD102 pKa = 3.9PPVTVTLTVTFQQ114 pKa = 2.95

Molecular weight:
12.83 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

2281

114

620

380.2

42.21

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.612 ± 0.666

2.499 ± 0.604

6.357 ± 0.644

5.042 ± 0.414

3.902 ± 0.455

7.541 ± 0.841

1.929 ± 0.288

4.603 ± 0.551

5.48 ± 0.621

8.242 ± 0.664

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.666 ± 0.285

3.683 ± 0.287

7.321 ± 1.289

4.428 ± 0.382

5.305 ± 0.602

7.453 ± 0.667

7.716 ± 0.752

6.401 ± 0.235

1.622 ± 0.339

3.2 ± 0.58

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski