Erethizon dorsatum papillomavirus 1

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Sigmapapillomavirus; Sigmapapillomavirus 1

Average proteome isoelectric point is 6.34

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q5IRF2|Q5IRF2_9PAPI E4 OS=Erethizon dorsatum papillomavirus 1 OX=291590 GN=E4 PE=4 SV=1
MM1 pKa = 6.98VVRR4 pKa = 11.84RR5 pKa = 11.84RR6 pKa = 11.84IKK8 pKa = 10.27RR9 pKa = 11.84ANPTQLYY16 pKa = 6.6ATCKK20 pKa = 8.99ITGTCPPDD28 pKa = 4.08IINKK32 pKa = 9.51IEE34 pKa = 4.17GNTVADD40 pKa = 5.78KK41 pKa = 10.44ILKK44 pKa = 8.61WGSTGVYY51 pKa = 10.09LGGLGIGTGRR61 pKa = 11.84GGGGVSLGGGSIGSARR77 pKa = 11.84PSVPAGSIGPGDD89 pKa = 4.78IITVDD94 pKa = 3.5AEE96 pKa = 4.29AGAVQPPVEE105 pKa = 4.63PPPTTSISGSARR117 pKa = 11.84RR118 pKa = 11.84PFGEE122 pKa = 4.18GFGRR126 pKa = 11.84QPLDD130 pKa = 3.94PIGIPRR136 pKa = 11.84PRR138 pKa = 11.84PSLPRR143 pKa = 11.84PTLDD147 pKa = 3.29TVPTDD152 pKa = 3.41VAVLEE157 pKa = 5.21GPHH160 pKa = 6.0TPFGAGGDD168 pKa = 3.56IAVLEE173 pKa = 4.55VPTPEE178 pKa = 3.89VGRR181 pKa = 11.84SVTARR186 pKa = 11.84TQYY189 pKa = 11.05NNPAFEE195 pKa = 4.19VSIHH199 pKa = 6.33SEE201 pKa = 4.07LPSAEE206 pKa = 4.19TSSVDD211 pKa = 3.1HH212 pKa = 6.69VYY214 pKa = 11.02VGTPSSGSFVGQDD227 pKa = 3.34VQFEE231 pKa = 4.62LPVLQAEE238 pKa = 4.38YY239 pKa = 10.61AILDD243 pKa = 4.03GQAEE247 pKa = 4.34TSFIEE252 pKa = 4.11HH253 pKa = 6.77GSYY256 pKa = 10.82SEE258 pKa = 4.5VPLTSTPDD266 pKa = 3.39PVLPTTEE273 pKa = 5.07AIASIRR279 pKa = 11.84PYY281 pKa = 10.56GRR283 pKa = 11.84QFGQVRR289 pKa = 11.84VGDD292 pKa = 3.76AAFLSRR298 pKa = 11.84PAVLFQAEE306 pKa = 4.22NPAYY310 pKa = 10.38DD311 pKa = 4.08PDD313 pKa = 3.85VSILFEE319 pKa = 5.32RR320 pKa = 11.84DD321 pKa = 3.15VADD324 pKa = 5.36LEE326 pKa = 4.29RR327 pKa = 11.84LPDD330 pKa = 4.14PFQDD334 pKa = 2.81IQYY337 pKa = 10.51LSRR340 pKa = 11.84PYY342 pKa = 8.98YY343 pKa = 9.17QRR345 pKa = 11.84RR346 pKa = 11.84ATGLRR351 pKa = 11.84LSRR354 pKa = 11.84IGRR357 pKa = 11.84RR358 pKa = 11.84EE359 pKa = 3.86GIIQTRR365 pKa = 11.84SGTRR369 pKa = 11.84VGSSHH374 pKa = 6.76HH375 pKa = 6.04FFYY378 pKa = 10.66DD379 pKa = 3.0ISDD382 pKa = 3.5ITPLEE387 pKa = 4.53EE388 pKa = 5.05IEE390 pKa = 4.0MDD392 pKa = 4.14SIGEE396 pKa = 4.02HH397 pKa = 5.9SLGVSTAAEE406 pKa = 4.0QPIEE410 pKa = 4.34VYY412 pKa = 10.71SEE414 pKa = 4.3ADD416 pKa = 3.35LLDD419 pKa = 3.78EE420 pKa = 4.43MEE422 pKa = 5.0EE423 pKa = 4.57GDD425 pKa = 3.75TLARR429 pKa = 11.84SSQLLLSFASVGEE442 pKa = 4.1EE443 pKa = 4.5GEE445 pKa = 5.13DD446 pKa = 3.23ITIQLPIDD454 pKa = 3.77LLSIEE459 pKa = 4.51KK460 pKa = 9.98PSTAFYY466 pKa = 10.26PDD468 pKa = 2.91TGVNIAYY475 pKa = 7.48TPTKK479 pKa = 8.94ITTPSLPWVPIDD491 pKa = 3.79DD492 pKa = 4.52TLDD495 pKa = 3.16TFQNYY500 pKa = 9.19NDD502 pKa = 4.19YY503 pKa = 11.01DD504 pKa = 3.98LHH506 pKa = 6.73PSLLPRR512 pKa = 11.84RR513 pKa = 11.84KK514 pKa = 9.31RR515 pKa = 11.84KK516 pKa = 9.59RR517 pKa = 11.84RR518 pKa = 11.84ILL520 pKa = 3.67

Molecular weight: 56.04 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q5IRF4|Q5IRF4_9PAPI Replication protein E1 OS=Erethizon dorsatum papillomavirus 1 OX=291590 GN=E1 PE=3 SV=1
MM1 pKa = 7.57EE2 pKa = 5.79RR3 pKa = 11.84LQHH6 pKa = 6.5RR7 pKa = 11.84LDD9 pKa = 3.62YY10 pKa = 9.35TQEE13 pKa = 4.59KK14 pKa = 10.39ILTLYY19 pKa = 10.52EE20 pKa = 4.53KK21 pKa = 10.67DD22 pKa = 3.39STDD25 pKa = 3.46INDD28 pKa = 5.39HH29 pKa = 6.17ISLWMAVRR37 pKa = 11.84HH38 pKa = 5.58EE39 pKa = 4.17NVLFHH44 pKa = 6.02TMRR47 pKa = 11.84KK48 pKa = 8.63RR49 pKa = 11.84GIVRR53 pKa = 11.84VMGRR57 pKa = 11.84SIPSLQASEE66 pKa = 5.1KK67 pKa = 8.86SAKK70 pKa = 8.76HH71 pKa = 5.95AIMMQLQLEE80 pKa = 4.54DD81 pKa = 4.07LAKK84 pKa = 10.41SPYY87 pKa = 10.27GLEE90 pKa = 3.89PWSLSEE96 pKa = 4.23TTLEE100 pKa = 4.55RR101 pKa = 11.84YY102 pKa = 7.74LAPPRR107 pKa = 11.84EE108 pKa = 4.21TFKK111 pKa = 11.14KK112 pKa = 10.46GGVHH116 pKa = 6.38VNVTFDD122 pKa = 3.68NEE124 pKa = 4.05EE125 pKa = 4.33SNSAEE130 pKa = 3.9YY131 pKa = 11.35VMWTYY136 pKa = 10.92IYY138 pKa = 10.11VTDD141 pKa = 5.31EE142 pKa = 3.86NGDD145 pKa = 3.18WHH147 pKa = 5.97KK148 pKa = 9.35TQGGVDD154 pKa = 3.21RR155 pKa = 11.84TGIYY159 pKa = 10.29YY160 pKa = 9.95IGVDD164 pKa = 3.8GSHH167 pKa = 6.9IYY169 pKa = 10.26YY170 pKa = 10.5VYY172 pKa = 10.83FEE174 pKa = 5.5DD175 pKa = 4.9EE176 pKa = 4.41AAQHH180 pKa = 6.09SRR182 pKa = 11.84TGQYY186 pKa = 8.66TVNSDD191 pKa = 3.17QDD193 pKa = 3.49VSDD196 pKa = 3.99PVINTDD202 pKa = 2.79SSRR205 pKa = 11.84NRR207 pKa = 11.84EE208 pKa = 4.21TGEE211 pKa = 3.56EE212 pKa = 4.18TPRR215 pKa = 11.84RR216 pKa = 11.84RR217 pKa = 11.84GTYY220 pKa = 9.8LRR222 pKa = 11.84RR223 pKa = 11.84SSPAAPARR231 pKa = 11.84PTPPQRR237 pKa = 11.84SRR239 pKa = 11.84QRR241 pKa = 11.84KK242 pKa = 8.41RR243 pKa = 11.84SPAGPTTNTTPEE255 pKa = 4.01TRR257 pKa = 11.84PTLLSARR264 pKa = 11.84NRR266 pKa = 11.84RR267 pKa = 11.84SRR269 pKa = 11.84SGRR272 pKa = 11.84SPSATGGRR280 pKa = 11.84HH281 pKa = 4.07QARR284 pKa = 11.84HH285 pKa = 5.74RR286 pKa = 11.84SSAEE290 pKa = 3.76RR291 pKa = 11.84PGPTPQFYY299 pKa = 10.89LIGCRR304 pKa = 11.84GPVNTLRR311 pKa = 11.84CYY313 pKa = 10.39RR314 pKa = 11.84FKK316 pKa = 10.92LKK318 pKa = 10.24KK319 pKa = 10.1RR320 pKa = 11.84PNPDD324 pKa = 2.08ITYY327 pKa = 10.38ISTTFNWTAPQGTDD341 pKa = 2.42RR342 pKa = 11.84CGSGRR347 pKa = 11.84FLIAFTSKK355 pKa = 7.11EE356 pKa = 4.14HH357 pKa = 7.04RR358 pKa = 11.84DD359 pKa = 3.59EE360 pKa = 5.22FYY362 pKa = 11.05VAARR366 pKa = 11.84PPPNIGLFKK375 pKa = 11.04GEE377 pKa = 4.78CEE379 pKa = 4.42TII381 pKa = 3.47

Molecular weight: 43.55 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2416

107

604

345.1

38.86

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.919 ± 0.433

2.401 ± 0.912

6.333 ± 0.613

6.126 ± 0.39

3.891 ± 0.514

6.788 ± 0.87

2.608 ± 0.379

4.76 ± 0.729

4.139 ± 0.752

8.982 ± 1.076

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.821 ± 0.437

3.394 ± 0.534

6.705 ± 1.069

4.429 ± 0.333

7.285 ± 0.856

6.664 ± 0.67

7.119 ± 0.514

5.96 ± 0.619

1.118 ± 0.19

3.56 ± 0.329
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski