Human papillomavirus 9

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Betapapillomavirus; Betapapillomavirus 2

Average proteome isoelectric point is 5.85

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q02480|VL1_HPV09 Major capsid protein L1 OS=Human papillomavirus 9 OX=10621 GN=L1 PE=3 SV=2
MM1 pKa = 7.4IGKK4 pKa = 8.52EE5 pKa = 3.76ATIPEE10 pKa = 4.48VVLEE14 pKa = 4.17LQEE17 pKa = 4.89LVQPTADD24 pKa = 3.45LHH26 pKa = 7.11CYY28 pKa = 10.26EE29 pKa = 5.08EE30 pKa = 4.54LTEE33 pKa = 4.52EE34 pKa = 4.17PAEE37 pKa = 4.13EE38 pKa = 4.26EE39 pKa = 4.29QCLTPYY45 pKa = 10.41KK46 pKa = 10.16IVAGCGCGARR56 pKa = 11.84LRR58 pKa = 11.84LYY60 pKa = 10.93VLATNLGIRR69 pKa = 11.84AQQEE73 pKa = 4.23LLLGDD78 pKa = 3.67IQLVCPEE85 pKa = 3.69CRR87 pKa = 11.84GRR89 pKa = 11.84LRR91 pKa = 11.84HH92 pKa = 5.58EE93 pKa = 4.03

Molecular weight: 10.39 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P36801|VE6_HPV09 Protein E6 OS=Human papillomavirus 9 OX=10621 GN=E6 PE=3 SV=1
MM1 pKa = 6.95EE2 pKa = 4.43TLSARR7 pKa = 11.84FNALQEE13 pKa = 4.28TLMDD17 pKa = 4.67LYY19 pKa = 11.24EE20 pKa = 4.58SGRR23 pKa = 11.84EE24 pKa = 3.93DD25 pKa = 3.48LQSQIDD31 pKa = 3.25HH32 pKa = 6.24WQTLRR37 pKa = 11.84QEE39 pKa = 4.4QILLHH44 pKa = 5.12YY45 pKa = 9.83ARR47 pKa = 11.84KK48 pKa = 9.52NGVMRR53 pKa = 11.84LGYY56 pKa = 10.31QPVPPLATSEE66 pKa = 4.14QKK68 pKa = 11.07AKK70 pKa = 10.79DD71 pKa = 3.87AIGMVLLLQSLQRR84 pKa = 11.84SAYY87 pKa = 8.84GQEE90 pKa = 3.94PWTLAQTSLEE100 pKa = 4.19AVRR103 pKa = 11.84SPPAYY108 pKa = 9.98AFKK111 pKa = 10.67KK112 pKa = 9.46GPQNIEE118 pKa = 3.71VVYY121 pKa = 10.94DD122 pKa = 3.85GDD124 pKa = 4.11PDD126 pKa = 3.91NVMSYY131 pKa = 8.35TIWNFIYY138 pKa = 10.36YY139 pKa = 7.86QTVNDD144 pKa = 3.51TWEE147 pKa = 4.23KK148 pKa = 9.26VQGHH152 pKa = 5.4VDD154 pKa = 3.48YY155 pKa = 11.12FGAYY159 pKa = 8.98YY160 pKa = 10.73FEE162 pKa = 4.79GTVKK166 pKa = 9.88TYY168 pKa = 10.85YY169 pKa = 10.3INFDD173 pKa = 3.42KK174 pKa = 11.16DD175 pKa = 2.74AARR178 pKa = 11.84YY179 pKa = 8.73GRR181 pKa = 11.84TGVWEE186 pKa = 3.79VHH188 pKa = 4.71VNKK191 pKa = 10.43DD192 pKa = 2.96IVFAPVTSSSPPTGDD207 pKa = 2.9GGEE210 pKa = 4.37TSKK213 pKa = 9.16HH214 pKa = 4.27TLSRR218 pKa = 11.84SGSPTTSRR226 pKa = 11.84LPATTVPTGGSRR238 pKa = 11.84TSSRR242 pKa = 11.84RR243 pKa = 11.84YY244 pKa = 7.87QRR246 pKa = 11.84KK247 pKa = 9.03ASSPTTRR254 pKa = 11.84KK255 pKa = 9.36KK256 pKa = 10.32RR257 pKa = 11.84QRR259 pKa = 11.84QGEE262 pKa = 4.49GEE264 pKa = 4.26GEE266 pKa = 4.45GEE268 pKa = 4.42GEE270 pKa = 3.83EE271 pKa = 4.26TNYY274 pKa = 10.07RR275 pKa = 11.84RR276 pKa = 11.84QRR278 pKa = 11.84SRR280 pKa = 11.84SKK282 pKa = 10.89GRR284 pKa = 11.84TEE286 pKa = 3.84TEE288 pKa = 3.5RR289 pKa = 11.84GGEE292 pKa = 3.6RR293 pKa = 11.84RR294 pKa = 11.84RR295 pKa = 11.84RR296 pKa = 11.84GRR298 pKa = 11.84SSSADD303 pKa = 2.99STTPTDD309 pKa = 3.16RR310 pKa = 11.84RR311 pKa = 11.84RR312 pKa = 11.84GRR314 pKa = 11.84GGGRR318 pKa = 11.84GPTTRR323 pKa = 11.84SQSRR327 pKa = 11.84SRR329 pKa = 11.84SRR331 pKa = 11.84SHH333 pKa = 5.79SRR335 pKa = 11.84SRR337 pKa = 11.84SRR339 pKa = 11.84GGTASRR345 pKa = 11.84VGVSPDD351 pKa = 3.16EE352 pKa = 4.05VGTRR356 pKa = 11.84VRR358 pKa = 11.84SVGAGHH364 pKa = 7.27HH365 pKa = 6.02GRR367 pKa = 11.84LARR370 pKa = 11.84LLAEE374 pKa = 4.86AKK376 pKa = 10.36DD377 pKa = 3.89PPLMLLRR384 pKa = 11.84GDD386 pKa = 4.1ANVLKK391 pKa = 10.36CYY393 pKa = 10.39RR394 pKa = 11.84FRR396 pKa = 11.84EE397 pKa = 4.17RR398 pKa = 11.84KK399 pKa = 9.12KK400 pKa = 10.4KK401 pKa = 10.03RR402 pKa = 11.84GLVKK406 pKa = 10.5YY407 pKa = 10.83YY408 pKa = 9.21STTWSWVGEE417 pKa = 4.18DD418 pKa = 3.07SCDD421 pKa = 3.11RR422 pKa = 11.84VGRR425 pKa = 11.84ARR427 pKa = 11.84MILAFDD433 pKa = 4.03TYY435 pKa = 7.77EE436 pKa = 3.99HH437 pKa = 6.51RR438 pKa = 11.84QQFIRR443 pKa = 11.84TMKK446 pKa = 10.61LPPTVDD452 pKa = 2.77WSLGNVDD459 pKa = 5.38DD460 pKa = 5.05LL461 pKa = 5.06

Molecular weight: 52.14 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

2347

93

605

391.2

44.16

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.667 ± 0.366

2.13 ± 0.769

6.135 ± 0.45

6.562 ± 0.55

3.963 ± 0.663

6.647 ± 0.997

1.96 ± 0.104

4.602 ± 0.767

4.602 ± 0.813

8.649 ± 1.003

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.619 ± 0.292

3.707 ± 0.843

5.411 ± 0.735

5.198 ± 0.35

7.073 ± 1.461

7.414 ± 0.766

6.945 ± 0.732

6.732 ± 0.668

1.193 ± 0.316

3.792 ± 0.318
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski