Amino acid dipepetide frequency for Triticum urartu (Red wild einkorn) (Crithodium urartu)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.901AlaAla: 9.901 ± 0.048	1.578AlaCys: 1.578 ± 0.012	4.13AlaAsp: 4.13 ± 0.019	4.859AlaGlu: 4.859 ± 0.03	2.867AlaPhe: 2.867 ± 0.017	6.074AlaGly: 6.074 ± 0.032	1.777AlaHis: 1.777 ± 0.011	3.639AlaIle: 3.639 ± 0.021	3.915AlaLys: 3.915 ± 0.02	7.671AlaLeu: 7.671 ± 0.031	2.284AlaMet: 2.284 ± 0.015	2.627AlaAsn: 2.627 ± 0.015	4.246AlaPro: 4.246 ± 0.027	2.479AlaGln: 2.479 ± 0.017	4.837AlaArg: 4.837 ± 0.022	6.681AlaSer: 6.681 ± 0.026	4.51AlaThr: 4.51 ± 0.021	6.173AlaVal: 6.173 ± 0.026	0.992AlaTrp: 0.992 ± 0.01	1.971AlaTyr: 1.971 ± 0.014	0.003AlaXaa: 0.003 ± 0.001
Cys	1.357CysAla: 1.357 ± 0.012	0.621CysCys: 0.621 ± 0.008	0.974CysAsp: 0.974 ± 0.01	0.87CysGlu: 0.87 ± 0.009	0.881CysPhe: 0.881 ± 0.009	1.544CysGly: 1.544 ± 0.013	0.557CysHis: 0.557 ± 0.007	1.001CysIle: 1.001 ± 0.009	1.051CysLys: 1.051 ± 0.011	1.936CysLeu: 1.936 ± 0.014	0.491CysMet: 0.491 ± 0.006	0.782CysAsn: 0.782 ± 0.009	1.115CysPro: 1.115 ± 0.011	0.626CysGln: 0.626 ± 0.007	1.34CysArg: 1.34 ± 0.011	1.926CysSer: 1.926 ± 0.014	1.015CysThr: 1.015 ± 0.01	1.228CysVal: 1.228 ± 0.011	0.286CysTrp: 0.286 ± 0.005	0.559CysTyr: 0.559 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.547AspAla: 4.547 ± 0.021	1.009AspCys: 1.009 ± 0.009	4.093AspAsp: 4.093 ± 0.028	3.953AspGlu: 3.953 ± 0.023	2.083AspPhe: 2.083 ± 0.013	4.595AspGly: 4.595 ± 0.022	1.315AspHis: 1.315 ± 0.012	2.851AspIle: 2.851 ± 0.018	2.587AspLys: 2.587 ± 0.017	5.153AspLeu: 5.153 ± 0.022	1.548AspMet: 1.548 ± 0.011	1.901AspAsn: 1.901 ± 0.014	2.717AspPro: 2.717 ± 0.015	1.668AspGln: 1.668 ± 0.013	2.665AspArg: 2.665 ± 0.016	3.567AspSer: 3.567 ± 0.019	2.385AspThr: 2.385 ± 0.016	3.973AspVal: 3.973 ± 0.018	0.73AspTrp: 0.73 ± 0.008	1.483AspTyr: 1.483 ± 0.012	0.001AspXaa: 0.001 ± 0.0
Glu	5.235GluAla: 5.235 ± 0.028	0.93GluCys: 0.93 ± 0.01	3.824GluAsp: 3.824 ± 0.023	5.797GluGlu: 5.797 ± 0.043	2.072GluPhe: 2.072 ± 0.013	3.931GluGly: 3.931 ± 0.019	1.486GluHis: 1.486 ± 0.011	3.086GluIle: 3.086 ± 0.018	3.786GluLys: 3.786 ± 0.025	6.048GluLeu: 6.048 ± 0.029	1.744GluMet: 1.744 ± 0.014	2.25GluAsn: 2.25 ± 0.014	2.27GluPro: 2.27 ± 0.017	2.274GluGln: 2.274 ± 0.016	3.434GluArg: 3.434 ± 0.022	3.736GluSer: 3.736 ± 0.02	2.655GluThr: 2.655 ± 0.017	4.196GluVal: 4.196 ± 0.02	0.78GluTrp: 0.78 ± 0.007	1.564GluTyr: 1.564 ± 0.012	0.002GluXaa: 0.002 ± 0.0
Phe	2.745PheAla: 2.745 ± 0.016	0.856PheCys: 0.856 ± 0.01	2.188PheAsp: 2.188 ± 0.015	1.924PheGlu: 1.924 ± 0.013	1.772PhePhe: 1.772 ± 0.014	2.94PheGly: 2.94 ± 0.018	1.03PheHis: 1.03 ± 0.01	1.738PheIle: 1.738 ± 0.012	1.641PheLys: 1.641 ± 0.012	3.951PheLeu: 3.951 ± 0.021	0.93PheMet: 0.93 ± 0.008	1.358PheAsn: 1.358 ± 0.011	1.91PhePro: 1.91 ± 0.013	1.283PheGln: 1.283 ± 0.01	2.057PheArg: 2.057 ± 0.015	3.345PheSer: 3.345 ± 0.019	1.864PheThr: 1.864 ± 0.014	2.696PheVal: 2.696 ± 0.016	0.536PheTrp: 0.536 ± 0.007	1.123PheTyr: 1.123 ± 0.011	0.001PheXaa: 0.001 ± 0.0
Gly	5.734GlyAla: 5.734 ± 0.027	1.555GlyCys: 1.555 ± 0.014	4.029GlyAsp: 4.029 ± 0.022	4.045GlyGlu: 4.045 ± 0.021	2.925GlyPhe: 2.925 ± 0.015	6.771GlyGly: 6.771 ± 0.046	1.885GlyHis: 1.885 ± 0.014	3.277GlyIle: 3.277 ± 0.016	3.789GlyLys: 3.789 ± 0.019	6.204GlyLeu: 6.204 ± 0.027	1.809GlyMet: 1.809 ± 0.012	2.816GlyAsn: 2.816 ± 0.018	2.805GlyPro: 2.805 ± 0.017	2.348GlyGln: 2.348 ± 0.018	4.651GlyArg: 4.651 ± 0.023	5.955GlySer: 5.955 ± 0.033	3.629GlyThr: 3.629 ± 0.02	4.833GlyVal: 4.833 ± 0.022	1.03GlyTrp: 1.03 ± 0.011	2.089GlyTyr: 2.089 ± 0.014	0.004GlyXaa: 0.004 ± 0.0
His	1.952HisAla: 1.952 ± 0.014	0.578HisCys: 0.578 ± 0.007	1.368HisAsp: 1.368 ± 0.01	1.315HisGlu: 1.315 ± 0.011	0.983HisPhe: 0.983 ± 0.009	2.215HisGly: 2.215 ± 0.016	0.995HisHis: 0.995 ± 0.01	1.187HisIle: 1.187 ± 0.011	1.07HisLys: 1.07 ± 0.011	2.72HisLeu: 2.72 ± 0.017	0.631HisMet: 0.631 ± 0.007	0.888HisAsn: 0.888 ± 0.01	1.502HisPro: 1.502 ± 0.013	0.978HisGln: 0.978 ± 0.009	1.676HisArg: 1.676 ± 0.012	1.667HisSer: 1.667 ± 0.014	1.097HisThr: 1.097 ± 0.01	1.787HisVal: 1.787 ± 0.014	0.325HisTrp: 0.325 ± 0.005	0.682HisTyr: 0.682 ± 0.008	0.001HisXaa: 0.001 ± 0.0
Ile	3.574IleAla: 3.574 ± 0.017	1.029IleCys: 1.029 ± 0.01	2.614IleAsp: 2.614 ± 0.017	2.541IleGlu: 2.541 ± 0.015	1.912IlePhe: 1.912 ± 0.015	3.194IleGly: 3.194 ± 0.017	1.205IleHis: 1.205 ± 0.01	2.41IleIle: 2.41 ± 0.018	2.387IleLys: 2.387 ± 0.016	4.59IleLeu: 4.59 ± 0.021	1.101IleMet: 1.101 ± 0.01	1.717IleAsn: 1.717 ± 0.014	2.588IlePro: 2.588 ± 0.022	1.638IleGln: 1.638 ± 0.012	2.469IleArg: 2.469 ± 0.015	3.961IleSer: 3.961 ± 0.021	2.457IleThr: 2.457 ± 0.016	3.236IleVal: 3.236 ± 0.02	0.664IleTrp: 0.664 ± 0.008	1.294IleTyr: 1.294 ± 0.011	0.001IleXaa: 0.001 ± 0.0
Lys	3.98LysAla: 3.98 ± 0.021	0.91LysCys: 0.91 ± 0.009	2.875LysAsp: 2.875 ± 0.02	3.856LysGlu: 3.856 ± 0.024	1.723LysPhe: 1.723 ± 0.013	3.293LysGly: 3.293 ± 0.017	1.265LysHis: 1.265 ± 0.012	2.654LysIle: 2.654 ± 0.016	3.828LysLys: 3.828 ± 0.027	5.263LysLeu: 5.263 ± 0.026	1.369LysMet: 1.369 ± 0.012	2.02LysAsn: 2.02 ± 0.015	2.3LysPro: 2.3 ± 0.017	1.948LysGln: 1.948 ± 0.015	3.181LysArg: 3.181 ± 0.021	3.473LysSer: 3.473 ± 0.019	2.4LysThr: 2.4 ± 0.018	3.441LysVal: 3.441 ± 0.018	0.645LysTrp: 0.645 ± 0.008	1.403LysTyr: 1.403 ± 0.01	0.001LysXaa: 0.001 ± 0.0
Leu	7.913LeuAla: 7.913 ± 0.031	1.999LeuCys: 1.999 ± 0.014	5.322LeuAsp: 5.322 ± 0.023	6.001LeuGlu: 6.001 ± 0.031	3.521LeuPhe: 3.521 ± 0.02	6.258LeuGly: 6.258 ± 0.026	2.885LeuHis: 2.885 ± 0.018	3.949LeuIle: 3.949 ± 0.02	5.11LeuLys: 5.11 ± 0.024	10.578LeuLeu: 10.578 ± 0.047	2.151LeuMet: 2.151 ± 0.014	3.171LeuAsn: 3.171 ± 0.017	5.709LeuPro: 5.709 ± 0.026	4.213LeuGln: 4.213 ± 0.022	6.169LeuArg: 6.169 ± 0.028	7.934LeuSer: 7.934 ± 0.039	4.492LeuThr: 4.492 ± 0.025	6.963LeuVal: 6.963 ± 0.028	1.183LeuTrp: 1.183 ± 0.011	2.383LeuTyr: 2.383 ± 0.017	0.002LeuXaa: 0.002 ± 0.0
Met	2.707MetAla: 2.707 ± 0.017	0.399MetCys: 0.399 ± 0.006	1.547MetAsp: 1.547 ± 0.012	1.951MetGlu: 1.951 ± 0.014	0.848MetPhe: 0.848 ± 0.009	1.682MetGly: 1.682 ± 0.014	0.627MetHis: 0.627 ± 0.007	1.055MetIle: 1.055 ± 0.01	1.396MetLys: 1.396 ± 0.012	2.426MetLeu: 2.426 ± 0.015	0.722MetMet: 0.722 ± 0.008	0.86MetAsn: 0.86 ± 0.009	1.325MetPro: 1.325 ± 0.013	0.959MetGln: 0.959 ± 0.01	1.365MetArg: 1.365 ± 0.009	1.835MetSer: 1.835 ± 0.012	1.16MetThr: 1.16 ± 0.01	1.823MetVal: 1.823 ± 0.013	0.299MetTrp: 0.299 ± 0.005	0.639MetTyr: 0.639 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.535AsnAla: 2.535 ± 0.015	0.749AsnCys: 0.749 ± 0.009	1.752AsnAsp: 1.752 ± 0.013	1.857AsnGlu: 1.857 ± 0.015	1.497AsnPhe: 1.497 ± 0.011	2.8AsnGly: 2.8 ± 0.016	0.934AsnHis: 0.934 ± 0.009	2.055AsnIle: 2.055 ± 0.015	1.914AsnLys: 1.914 ± 0.016	3.964AsnLeu: 3.964 ± 0.027	1.044AsnMet: 1.044 ± 0.009	1.748AsnAsn: 1.748 ± 0.02	1.898AsnPro: 1.898 ± 0.014	1.305AsnGln: 1.305 ± 0.012	1.782AsnArg: 1.782 ± 0.012	2.808AsnSer: 2.808 ± 0.019	1.775AsnThr: 1.775 ± 0.013	2.367AsnVal: 2.367 ± 0.014	0.484AsnTrp: 0.484 ± 0.007	1.041AsnTyr: 1.041 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	4.603ProAla: 4.603 ± 0.023	0.982ProCys: 0.982 ± 0.01	2.747ProAsp: 2.747 ± 0.016	3.315ProGlu: 3.315 ± 0.02	1.851ProPhe: 1.851 ± 0.014	3.409ProGly: 3.409 ± 0.019	1.233ProHis: 1.233 ± 0.01	1.954ProIle: 1.954 ± 0.013	2.341ProLys: 2.341 ± 0.016	4.408ProLeu: 4.408 ± 0.022	1.148ProMet: 1.148 ± 0.01	1.831ProAsn: 1.831 ± 0.014	4.247ProPro: 4.247 ± 0.035	1.789ProGln: 1.789 ± 0.016	3.124ProArg: 3.124 ± 0.017	4.958ProSer: 4.958 ± 0.025	2.729ProThr: 2.729 ± 0.015	3.392ProVal: 3.392 ± 0.018	0.715ProTrp: 0.715 ± 0.008	1.309ProTyr: 1.309 ± 0.013	0.002ProXaa: 0.002 ± 0.0
Gln	2.674GlnAla: 2.674 ± 0.016	0.634GlnCys: 0.634 ± 0.007	1.727GlnAsp: 1.727 ± 0.012	2.342GlnGlu: 2.342 ± 0.017	1.226GlnPhe: 1.226 ± 0.01	2.381GlnGly: 2.381 ± 0.015	1.032GlnHis: 1.032 ± 0.011	1.713GlnIle: 1.713 ± 0.014	1.889GlnLys: 1.889 ± 0.015	3.635GlnLeu: 3.635 ± 0.018	0.942GlnMet: 0.942 ± 0.009	1.314GlnAsn: 1.314 ± 0.012	1.837GlnPro: 1.837 ± 0.017	2.21GlnGln: 2.21 ± 0.035	2.251GlnArg: 2.251 ± 0.014	2.431GlnSer: 2.431 ± 0.016	1.527GlnThr: 1.527 ± 0.014	2.333GlnVal: 2.333 ± 0.014	0.473GlnTrp: 0.473 ± 0.007	0.896GlnTyr: 0.896 ± 0.008	0.001GlnXaa: 0.001 ± 0.0
Arg	4.516ArgAla: 4.516 ± 0.023	1.334ArgCys: 1.334 ± 0.013	2.957ArgAsp: 2.957 ± 0.017	3.359ArgGlu: 3.359 ± 0.019	2.239ArgPhe: 2.239 ± 0.015	4.059ArgGly: 4.059 ± 0.024	1.664ArgHis: 1.664 ± 0.013	2.67ArgIle: 2.67 ± 0.014	3.402ArgLys: 3.402 ± 0.02	5.823ArgLeu: 5.823 ± 0.026	1.507ArgMet: 1.507 ± 0.012	2.123ArgAsn: 2.123 ± 0.014	3.032ArgPro: 3.032 ± 0.019	2.09ArgGln: 2.09 ± 0.015	5.427ArgArg: 5.427 ± 0.034	4.69ArgSer: 4.69 ± 0.026	2.702ArgThr: 2.702 ± 0.017	3.778ArgVal: 3.778 ± 0.021	0.981ArgTrp: 0.981 ± 0.009	1.6ArgTyr: 1.6 ± 0.013	0.003ArgXaa: 0.003 ± 0.0
Ser	5.997SerAla: 5.997 ± 0.024	1.768SerCys: 1.768 ± 0.013	3.967SerAsp: 3.967 ± 0.019	3.997SerGlu: 3.997 ± 0.027	3.336SerPhe: 3.336 ± 0.018	5.938SerGly: 5.938 ± 0.028	1.8SerHis: 1.8 ± 0.013	3.741SerIle: 3.741 ± 0.02	3.836SerLys: 3.836 ± 0.022	7.841SerLeu: 7.841 ± 0.032	2.087SerMet: 2.087 ± 0.014	3.046SerAsn: 3.046 ± 0.02	4.271SerPro: 4.271 ± 0.026	2.492SerGln: 2.492 ± 0.017	4.53SerArg: 4.53 ± 0.023	9.092SerSer: 9.092 ± 0.044	4.454SerThr: 4.454 ± 0.024	4.99SerVal: 4.99 ± 0.021	1.216SerTrp: 1.216 ± 0.011	2.126SerTyr: 2.126 ± 0.015	0.002SerXaa: 0.002 ± 0.0
Thr	4.122ThrAla: 4.122 ± 0.02	1.022ThrCys: 1.022 ± 0.009	2.442ThrAsp: 2.442 ± 0.017	2.709ThrGlu: 2.709 ± 0.02	1.863ThrPhe: 1.863 ± 0.014	3.704ThrGly: 3.704 ± 0.019	1.047ThrHis: 1.047 ± 0.01	2.481ThrIle: 2.481 ± 0.014	2.4ThrLys: 2.4 ± 0.015	4.499ThrLeu: 4.499 ± 0.022	1.315ThrMet: 1.315 ± 0.01	1.842ThrAsn: 1.842 ± 0.013	2.742ThrPro: 2.742 ± 0.018	1.404ThrGln: 1.404 ± 0.011	2.658ThrArg: 2.658 ± 0.016	4.318ThrSer: 4.318 ± 0.024	3.072ThrThr: 3.072 ± 0.021	3.643ThrVal: 3.643 ± 0.019	0.686ThrTrp: 0.686 ± 0.008	1.351ThrTyr: 1.351 ± 0.012	0.001ThrXaa: 0.001 ± 0.0
Val	6.197ValAla: 6.197 ± 0.028	1.294ValCys: 1.294 ± 0.01	4.054ValAsp: 4.054 ± 0.021	4.225ValGlu: 4.225 ± 0.022	2.61ValPhe: 2.61 ± 0.019	4.583ValGly: 4.583 ± 0.021	1.796ValHis: 1.796 ± 0.013	3.113ValIle: 3.113 ± 0.015	3.377ValLys: 3.377 ± 0.018	7.094ValLeu: 7.094 ± 0.027	1.649ValMet: 1.649 ± 0.013	2.245ValAsn: 2.245 ± 0.014	3.744ValPro: 3.744 ± 0.022	2.416ValGln: 2.416 ± 0.014	3.808ValArg: 3.808 ± 0.017	5.059ValSer: 5.059 ± 0.022	3.404ValThr: 3.404 ± 0.019	5.584ValVal: 5.584 ± 0.027	0.881ValTrp: 0.881 ± 0.009	1.944ValTyr: 1.944 ± 0.014	0.001ValXaa: 0.001 ± 0.0
Trp	0.981TrpAla: 0.981 ± 0.009	0.286TrpCys: 0.286 ± 0.006	0.714TrpAsp: 0.714 ± 0.009	0.79TrpGlu: 0.79 ± 0.009	0.529TrpPhe: 0.529 ± 0.007	0.792TrpGly: 0.792 ± 0.008	0.35TrpHis: 0.35 ± 0.005	0.663TrpIle: 0.663 ± 0.007	0.803TrpLys: 0.803 ± 0.009	1.29TrpLeu: 1.29 ± 0.011	0.377TrpMet: 0.377 ± 0.006	0.599TrpAsn: 0.599 ± 0.007	0.622TrpPro: 0.622 ± 0.009	0.477TrpGln: 0.477 ± 0.006	1.054TrpArg: 1.054 ± 0.012	1.068TrpSer: 1.068 ± 0.01	0.679TrpThr: 0.679 ± 0.008	0.873TrpVal: 0.873 ± 0.009	0.26TrpTrp: 0.26 ± 0.005	0.346TrpTyr: 0.346 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.943TyrAla: 1.943 ± 0.014	0.628TyrCys: 0.628 ± 0.008	1.501TyrAsp: 1.501 ± 0.011	1.39TyrGlu: 1.39 ± 0.011	1.15TyrPhe: 1.15 ± 0.011	2.018TyrGly: 2.018 ± 0.016	0.733TyrHis: 0.733 ± 0.008	1.346TyrIle: 1.346 ± 0.011	1.304TyrLys: 1.304 ± 0.012	2.807TyrLeu: 2.807 ± 0.017	0.776TyrMet: 0.776 ± 0.007	1.172TyrAsn: 1.172 ± 0.011	1.205TyrPro: 1.205 ± 0.011	0.869TyrGln: 0.869 ± 0.009	1.473TyrArg: 1.473 ± 0.013	2.021TyrSer: 2.021 ± 0.014	1.315TyrThr: 1.315 ± 0.011	1.766TyrVal: 1.766 ± 0.014	0.387TyrTrp: 0.387 ± 0.007	0.921TyrTyr: 0.921 ± 0.01	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.004XaaAla: 0.004 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.003XaaGly: 0.003 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.003XaaLeu: 0.003 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.003XaaPro: 0.003 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.003XaaArg: 0.003 ± 0.001	0.003XaaSer: 0.003 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.002XaaVal: 0.002 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.015XaaXaa: 0.015 ± 0.003

Statistics based on 33312 proteins (12117229 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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