Amino acid dipepetide frequency for Colletotrichum tanaceti

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.015AlaAla: 12.015 ± 0.087	1.139AlaCys: 1.139 ± 0.016	5.079AlaAsp: 5.079 ± 0.036	5.633AlaGlu: 5.633 ± 0.045	3.156AlaPhe: 3.156 ± 0.028	7.089AlaGly: 7.089 ± 0.05	1.956AlaHis: 1.956 ± 0.02	3.854AlaIle: 3.854 ± 0.026	4.0AlaLys: 4.0 ± 0.035	8.117AlaLeu: 8.117 ± 0.046	2.048AlaMet: 2.048 ± 0.017	2.951AlaAsn: 2.951 ± 0.025	5.481AlaPro: 5.481 ± 0.046	3.445AlaGln: 3.445 ± 0.031	5.77AlaArg: 5.77 ± 0.038	7.685AlaSer: 7.685 ± 0.047	5.562AlaThr: 5.562 ± 0.045	6.699AlaVal: 6.699 ± 0.049	1.264AlaTrp: 1.264 ± 0.017	2.127AlaTyr: 2.127 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	0.964CysAla: 0.964 ± 0.015	0.255CysCys: 0.255 ± 0.007	0.666CysAsp: 0.666 ± 0.014	0.57CysGlu: 0.57 ± 0.011	0.526CysPhe: 0.526 ± 0.01	0.978CysGly: 0.978 ± 0.018	0.33CysHis: 0.33 ± 0.008	0.595CysIle: 0.595 ± 0.011	0.468CysLys: 0.468 ± 0.01	1.201CysLeu: 1.201 ± 0.017	0.261CysMet: 0.261 ± 0.007	0.417CysAsn: 0.417 ± 0.009	0.685CysPro: 0.685 ± 0.013	0.417CysGln: 0.417 ± 0.008	0.836CysArg: 0.836 ± 0.014	0.875CysSer: 0.875 ± 0.015	0.646CysThr: 0.646 ± 0.011	0.825CysVal: 0.825 ± 0.012	0.218CysTrp: 0.218 ± 0.006	0.316CysTyr: 0.316 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.622AspAla: 5.622 ± 0.04	0.625AspCys: 0.625 ± 0.01	5.298AspAsp: 5.298 ± 0.053	4.643AspGlu: 4.643 ± 0.04	2.188AspPhe: 2.188 ± 0.019	5.07AspGly: 5.07 ± 0.043	1.286AspHis: 1.286 ± 0.017	2.636AspIle: 2.636 ± 0.024	2.386AspLys: 2.386 ± 0.026	5.083AspLeu: 5.083 ± 0.033	1.269AspMet: 1.269 ± 0.014	1.834AspAsn: 1.834 ± 0.021	3.393AspPro: 3.393 ± 0.023	1.749AspGln: 1.749 ± 0.017	3.259AspArg: 3.259 ± 0.033	3.792AspSer: 3.792 ± 0.033	2.781AspThr: 2.781 ± 0.025	4.214AspVal: 4.214 ± 0.038	0.868AspTrp: 0.868 ± 0.013	1.442AspTyr: 1.442 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.872GluAla: 5.872 ± 0.049	0.562GluCys: 0.562 ± 0.01	4.173GluAsp: 4.173 ± 0.039	5.244GluGlu: 5.244 ± 0.058	1.756GluPhe: 1.756 ± 0.02	4.032GluGly: 4.032 ± 0.035	1.381GluHis: 1.381 ± 0.018	2.518GluIle: 2.518 ± 0.022	3.328GluLys: 3.328 ± 0.034	4.912GluLeu: 4.912 ± 0.037	1.411GluMet: 1.411 ± 0.017	1.986GluAsn: 1.986 ± 0.022	2.98GluPro: 2.98 ± 0.039	2.26GluGln: 2.26 ± 0.025	3.954GluArg: 3.954 ± 0.036	3.904GluSer: 3.904 ± 0.033	3.425GluThr: 3.425 ± 0.028	3.71GluVal: 3.71 ± 0.033	0.838GluTrp: 0.838 ± 0.012	1.468GluTyr: 1.468 ± 0.019	0.001GluXaa: 0.001 ± 0.0
Phe	3.145PheAla: 3.145 ± 0.029	0.54PheCys: 0.54 ± 0.011	2.234PheAsp: 2.234 ± 0.019	1.963PheGlu: 1.963 ± 0.021	1.591PhePhe: 1.591 ± 0.021	2.862PheGly: 2.862 ± 0.028	0.847PheHis: 0.847 ± 0.012	1.505PheIle: 1.505 ± 0.018	1.355PheLys: 1.355 ± 0.016	3.255PheLeu: 3.255 ± 0.026	0.732PheMet: 0.732 ± 0.012	1.322PheAsn: 1.322 ± 0.017	1.88PhePro: 1.88 ± 0.021	1.248PheGln: 1.248 ± 0.015	2.031PheArg: 2.031 ± 0.019	2.793PheSer: 2.793 ± 0.022	1.965PheThr: 1.965 ± 0.021	2.489PheVal: 2.489 ± 0.03	0.613PheTrp: 0.613 ± 0.011	1.012PheTyr: 1.012 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	6.437GlyAla: 6.437 ± 0.049	0.911GlyCys: 0.911 ± 0.013	4.318GlyAsp: 4.318 ± 0.04	3.927GlyGlu: 3.927 ± 0.037	2.83GlyPhe: 2.83 ± 0.022	7.759GlyGly: 7.759 ± 0.075	1.905GlyHis: 1.905 ± 0.025	3.274GlyIle: 3.274 ± 0.027	3.225GlyLys: 3.225 ± 0.028	6.557GlyLeu: 6.557 ± 0.048	1.596GlyMet: 1.596 ± 0.018	2.583GlyAsn: 2.583 ± 0.025	3.882GlyPro: 3.882 ± 0.032	2.663GlyGln: 2.663 ± 0.027	4.986GlyArg: 4.986 ± 0.041	5.921GlySer: 5.921 ± 0.052	4.155GlyThr: 4.155 ± 0.046	5.095GlyVal: 5.095 ± 0.044	1.192GlyTrp: 1.192 ± 0.016	2.013GlyTyr: 2.013 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	2.028HisAla: 2.028 ± 0.02	0.34HisCys: 0.34 ± 0.009	1.433HisAsp: 1.433 ± 0.018	1.311HisGlu: 1.311 ± 0.016	0.885HisPhe: 0.885 ± 0.012	1.89HisGly: 1.89 ± 0.021	1.076HisHis: 1.076 ± 0.02	1.009HisIle: 1.009 ± 0.015	0.855HisLys: 0.855 ± 0.012	2.273HisLeu: 2.273 ± 0.021	0.491HisMet: 0.491 ± 0.01	0.793HisAsn: 0.793 ± 0.013	1.691HisPro: 1.691 ± 0.019	1.071HisGln: 1.071 ± 0.017	1.654HisArg: 1.654 ± 0.02	1.685HisSer: 1.685 ± 0.021	1.201HisThr: 1.201 ± 0.017	1.606HisVal: 1.606 ± 0.018	0.33HisTrp: 0.33 ± 0.009	0.648HisTyr: 0.648 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.792IleAla: 3.792 ± 0.033	0.604IleCys: 0.604 ± 0.012	2.499IleAsp: 2.499 ± 0.022	2.407IleGlu: 2.407 ± 0.025	1.628IlePhe: 1.628 ± 0.02	2.848IleGly: 2.848 ± 0.03	1.036IleHis: 1.036 ± 0.013	2.009IleIle: 2.009 ± 0.023	1.852IleLys: 1.852 ± 0.021	3.891IleLeu: 3.891 ± 0.028	0.918IleMet: 0.918 ± 0.013	1.523IleAsn: 1.523 ± 0.02	2.662IlePro: 2.662 ± 0.025	1.565IleGln: 1.565 ± 0.019	2.579IleArg: 2.579 ± 0.023	3.145IleSer: 3.145 ± 0.024	2.461IleThr: 2.461 ± 0.024	2.968IleVal: 2.968 ± 0.026	0.627IleTrp: 0.627 ± 0.011	1.147IleTyr: 1.147 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.128LysAla: 4.128 ± 0.035	0.456LysCys: 0.456 ± 0.011	2.52LysAsp: 2.52 ± 0.026	2.958LysGlu: 2.958 ± 0.035	1.255LysPhe: 1.255 ± 0.016	2.879LysGly: 2.879 ± 0.027	1.041LysHis: 1.041 ± 0.015	1.893LysIle: 1.893 ± 0.02	3.245LysLys: 3.245 ± 0.055	3.64LysLeu: 3.64 ± 0.03	1.019LysMet: 1.019 ± 0.014	1.556LysAsn: 1.556 ± 0.018	2.617LysPro: 2.617 ± 0.028	1.638LysGln: 1.638 ± 0.021	3.144LysArg: 3.144 ± 0.031	3.066LysSer: 3.066 ± 0.028	2.802LysThr: 2.802 ± 0.024	2.595LysVal: 2.595 ± 0.024	0.611LysTrp: 0.611 ± 0.012	1.159LysTyr: 1.159 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	8.537LeuAla: 8.537 ± 0.049	1.152LeuCys: 1.152 ± 0.017	5.282LeuAsp: 5.282 ± 0.042	5.289LeuGlu: 5.289 ± 0.041	3.174LeuPhe: 3.174 ± 0.028	6.541LeuGly: 6.541 ± 0.048	2.171LeuHis: 2.171 ± 0.023	3.256LeuIle: 3.256 ± 0.028	3.651LeuLys: 3.651 ± 0.031	8.361LeuLeu: 8.361 ± 0.07	1.698LeuMet: 1.698 ± 0.02	2.731LeuAsn: 2.731 ± 0.022	5.565LeuPro: 5.565 ± 0.06	3.472LeuGln: 3.472 ± 0.033	5.985LeuArg: 5.985 ± 0.041	6.708LeuSer: 6.708 ± 0.047	4.614LeuThr: 4.614 ± 0.035	6.026LeuVal: 6.026 ± 0.039	1.179LeuTrp: 1.179 ± 0.015	2.113LeuTyr: 2.113 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.362MetAla: 2.362 ± 0.022	0.237MetCys: 0.237 ± 0.007	1.216MetAsp: 1.216 ± 0.014	1.171MetGlu: 1.171 ± 0.013	0.717MetPhe: 0.717 ± 0.013	1.446MetGly: 1.446 ± 0.018	0.448MetHis: 0.448 ± 0.009	0.863MetIle: 0.863 ± 0.013	0.926MetLys: 0.926 ± 0.013	1.817MetLeu: 1.817 ± 0.021	0.607MetMet: 0.607 ± 0.011	0.732MetAsn: 0.732 ± 0.012	1.323MetPro: 1.323 ± 0.017	0.779MetGln: 0.779 ± 0.014	1.316MetArg: 1.316 ± 0.015	1.846MetSer: 1.846 ± 0.023	1.328MetThr: 1.328 ± 0.016	1.304MetVal: 1.304 ± 0.017	0.255MetTrp: 0.255 ± 0.007	0.496MetTyr: 0.496 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.996AsnAla: 2.996 ± 0.026	0.415AsnCys: 0.415 ± 0.009	1.905AsnAsp: 1.905 ± 0.02	1.739AsnGlu: 1.739 ± 0.018	1.221AsnPhe: 1.221 ± 0.016	2.933AsnGly: 2.933 ± 0.03	0.8AsnHis: 0.8 ± 0.014	1.716AsnIle: 1.716 ± 0.019	1.428AsnLys: 1.428 ± 0.018	2.923AsnLeu: 2.923 ± 0.026	0.811AsnMet: 0.811 ± 0.014	1.57AsnAsn: 1.57 ± 0.03	2.312AsnPro: 2.312 ± 0.023	1.178AsnGln: 1.178 ± 0.017	1.861AsnArg: 1.861 ± 0.018	2.416AsnSer: 2.416 ± 0.026	2.018AsnThr: 2.018 ± 0.02	2.2AsnVal: 2.2 ± 0.021	0.496AsnTrp: 0.496 ± 0.01	0.925AsnTyr: 0.925 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	6.216ProAla: 6.216 ± 0.051	0.548ProCys: 0.548 ± 0.012	3.454ProAsp: 3.454 ± 0.028	3.837ProGlu: 3.837 ± 0.037	2.031ProPhe: 2.031 ± 0.02	4.516ProGly: 4.516 ± 0.035	1.345ProHis: 1.345 ± 0.018	2.218ProIle: 2.218 ± 0.019	2.527ProLys: 2.527 ± 0.026	4.841ProLeu: 4.841 ± 0.036	1.076ProMet: 1.076 ± 0.017	2.022ProAsn: 2.022 ± 0.024	6.028ProPro: 6.028 ± 0.081	2.435ProGln: 2.435 ± 0.028	3.941ProArg: 3.941 ± 0.033	5.954ProSer: 5.954 ± 0.067	4.031ProThr: 4.031 ± 0.037	4.024ProVal: 4.024 ± 0.033	0.758ProTrp: 0.758 ± 0.014	1.408ProTyr: 1.408 ± 0.02	0.001ProXaa: 0.001 ± 0.0
Gln	3.421GlnAla: 3.421 ± 0.027	0.419GlnCys: 0.419 ± 0.011	2.008GlnAsp: 2.008 ± 0.019	2.129GlnGlu: 2.129 ± 0.025	1.138GlnPhe: 1.138 ± 0.015	2.44GlnGly: 2.44 ± 0.022	1.191GlnHis: 1.191 ± 0.02	1.568GlnIle: 1.568 ± 0.017	1.719GlnLys: 1.719 ± 0.022	3.202GlnLeu: 3.202 ± 0.028	0.858GlnMet: 0.858 ± 0.013	1.291GlnAsn: 1.291 ± 0.018	2.603GlnPro: 2.603 ± 0.033	3.051GlnGln: 3.051 ± 0.071	2.694GlnArg: 2.694 ± 0.024	2.744GlnSer: 2.744 ± 0.025	2.26GlnThr: 2.26 ± 0.032	2.163GlnVal: 2.163 ± 0.023	0.523GlnTrp: 0.523 ± 0.01	1.022GlnTyr: 1.022 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	5.292ArgAla: 5.292 ± 0.035	0.791ArgCys: 0.791 ± 0.013	3.875ArgAsp: 3.875 ± 0.037	3.958ArgGlu: 3.958 ± 0.029	2.191ArgPhe: 2.191 ± 0.022	4.384ArgGly: 4.384 ± 0.042	1.855ArgHis: 1.855 ± 0.02	2.653ArgIle: 2.653 ± 0.024	3.192ArgLys: 3.192 ± 0.028	5.888ArgLeu: 5.888 ± 0.044	1.33ArgMet: 1.33 ± 0.018	2.152ArgAsn: 2.152 ± 0.019	4.102ArgPro: 4.102 ± 0.032	2.752ArgGln: 2.752 ± 0.024	6.154ArgArg: 6.154 ± 0.054	4.815ArgSer: 4.815 ± 0.039	3.353ArgThr: 3.353 ± 0.03	3.912ArgVal: 3.912 ± 0.037	0.977ArgTrp: 0.977 ± 0.014	1.573ArgTyr: 1.573 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.886SerAla: 6.886 ± 0.052	0.874SerCys: 0.874 ± 0.014	4.005SerAsp: 4.005 ± 0.032	3.691SerGlu: 3.691 ± 0.036	2.843SerPhe: 2.843 ± 0.022	5.634SerGly: 5.634 ± 0.049	1.848SerHis: 1.848 ± 0.022	3.374SerIle: 3.374 ± 0.033	3.23SerLys: 3.23 ± 0.028	6.779SerLeu: 6.779 ± 0.047	1.627SerMet: 1.627 ± 0.02	2.669SerAsn: 2.669 ± 0.024	5.581SerPro: 5.581 ± 0.043	2.954SerGln: 2.954 ± 0.028	5.158SerArg: 5.158 ± 0.041	8.724SerSer: 8.724 ± 0.102	5.19SerThr: 5.19 ± 0.075	4.629SerVal: 4.629 ± 0.038	1.078SerTrp: 1.078 ± 0.015	1.861SerTyr: 1.861 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.677ThrAla: 5.677 ± 0.038	0.739ThrCys: 0.739 ± 0.013	2.761ThrAsp: 2.761 ± 0.025	2.958ThrGlu: 2.958 ± 0.034	2.086ThrPhe: 2.086 ± 0.02	4.219ThrGly: 4.219 ± 0.039	1.224ThrHis: 1.224 ± 0.016	2.718ThrIle: 2.718 ± 0.032	2.398ThrLys: 2.398 ± 0.022	4.986ThrLeu: 4.986 ± 0.047	1.211ThrMet: 1.211 ± 0.014	1.986ThrAsn: 1.986 ± 0.019	4.399ThrPro: 4.399 ± 0.039	1.952ThrGln: 1.952 ± 0.023	3.285ThrArg: 3.285 ± 0.026	5.044ThrSer: 5.044 ± 0.073	4.734ThrThr: 4.734 ± 0.082	3.853ThrVal: 3.853 ± 0.06	0.834ThrTrp: 0.834 ± 0.012	1.526ThrTyr: 1.526 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	6.402ValAla: 6.402 ± 0.044	0.854ValCys: 0.854 ± 0.013	4.228ValAsp: 4.228 ± 0.039	4.099ValGlu: 4.099 ± 0.032	2.56ValPhe: 2.56 ± 0.028	4.797ValGly: 4.797 ± 0.048	1.471ValHis: 1.471 ± 0.019	2.722ValIle: 2.722 ± 0.03	2.753ValLys: 2.753 ± 0.028	6.093ValLeu: 6.093 ± 0.044	1.313ValMet: 1.313 ± 0.017	2.147ValAsn: 2.147 ± 0.02	4.012ValPro: 4.012 ± 0.037	2.313ValGln: 2.313 ± 0.02	4.022ValArg: 4.022 ± 0.035	4.701ValSer: 4.701 ± 0.03	3.696ValThr: 3.696 ± 0.054	5.421ValVal: 5.421 ± 0.052	0.934ValTrp: 0.934 ± 0.014	1.688ValTyr: 1.688 ± 0.017	0.001ValXaa: 0.001 ± 0.0
Trp	1.201TrpAla: 1.201 ± 0.015	0.198TrpCys: 0.198 ± 0.006	0.914TrpAsp: 0.914 ± 0.012	0.817TrpGlu: 0.817 ± 0.012	0.532TrpPhe: 0.532 ± 0.008	0.939TrpGly: 0.939 ± 0.014	0.36TrpHis: 0.36 ± 0.009	0.658TrpIle: 0.658 ± 0.012	0.711TrpLys: 0.711 ± 0.012	1.308TrpLeu: 1.308 ± 0.016	0.356TrpMet: 0.356 ± 0.008	0.588TrpAsn: 0.588 ± 0.01	0.639TrpPro: 0.639 ± 0.011	0.543TrpGln: 0.543 ± 0.01	0.999TrpArg: 0.999 ± 0.014	1.024TrpSer: 1.024 ± 0.014	0.909TrpThr: 0.909 ± 0.016	0.897TrpVal: 0.897 ± 0.013	0.296TrpTrp: 0.296 ± 0.009	0.412TrpTyr: 0.412 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.076TyrAla: 2.076 ± 0.021	0.388TyrCys: 0.388 ± 0.009	1.574TyrAsp: 1.574 ± 0.019	1.371TyrGlu: 1.371 ± 0.015	1.077TyrPhe: 1.077 ± 0.015	1.973TyrGly: 1.973 ± 0.023	0.696TyrHis: 0.696 ± 0.01	1.126TyrIle: 1.126 ± 0.016	0.971TyrLys: 0.971 ± 0.014	2.379TyrLeu: 2.379 ± 0.025	0.56TyrMet: 0.56 ± 0.01	1.009TyrAsn: 1.009 ± 0.013	1.376TyrPro: 1.376 ± 0.018	0.961TyrGln: 0.961 ± 0.016	1.572TyrArg: 1.572 ± 0.019	1.788TyrSer: 1.788 ± 0.019	1.458TyrThr: 1.458 ± 0.019	1.592TyrVal: 1.592 ± 0.018	0.412TyrTrp: 0.412 ± 0.008	0.829TyrTyr: 0.829 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.112XaaXaa: 0.112 ± 0.024

Statistics based on 12168 proteins (5830596 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---