Enhydra lutris papillomavirus 1

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Lambdapapillomavirus; Lambdapapillomavirus 4

Average proteome isoelectric point is 6.4

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|W8R555|W8R555_9PAPI Major capsid protein L1 OS=Enhydra lutris papillomavirus 1 OX=1472717 GN=L1 PE=3 SV=1
MM1 pKa = 7.62FGLCPTLGEE10 pKa = 4.4VVLTEE15 pKa = 3.86QPEE18 pKa = 4.5AIDD21 pKa = 3.39LHH23 pKa = 8.68CYY25 pKa = 8.29EE26 pKa = 5.32HH27 pKa = 6.65MPSDD31 pKa = 3.89DD32 pKa = 4.03EE33 pKa = 4.51EE34 pKa = 4.99EE35 pKa = 4.37EE36 pKa = 4.3EE37 pKa = 4.17QTSRR41 pKa = 11.84DD42 pKa = 3.7LYY44 pKa = 10.61RR45 pKa = 11.84VSVDD49 pKa = 3.09CGACKK54 pKa = 9.61RR55 pKa = 11.84TVTLVVFADD64 pKa = 4.02LEE66 pKa = 4.92DD67 pKa = 3.68IQKK70 pKa = 10.08LHH72 pKa = 6.64SLLHH76 pKa = 5.14SVRR79 pKa = 11.84VVCEE83 pKa = 3.77SCLNPNNLNHH93 pKa = 6.88GGG95 pKa = 3.53

Molecular weight:
10.64 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|W8S105|W8S105_9PAPI Replication protein E1 OS=Enhydra lutris papillomavirus 1 OX=1472717 GN=E1 PE=3 SV=1
MM1 pKa = 7.08EE2 pKa = 5.13TLNQALNSVQEE13 pKa = 4.54DD14 pKa = 4.05LLSLYY19 pKa = 8.41EE20 pKa = 4.12QNSEE24 pKa = 4.76SITDD28 pKa = 4.7QIQHH32 pKa = 5.95WNLLRR37 pKa = 11.84RR38 pKa = 11.84EE39 pKa = 4.01QVILYY44 pKa = 6.84YY45 pKa = 10.69ARR47 pKa = 11.84EE48 pKa = 3.9RR49 pKa = 11.84GITRR53 pKa = 11.84LGMTLVPPRR62 pKa = 11.84HH63 pKa = 5.97VSQQKK68 pKa = 9.8AKK70 pKa = 10.53AAIEE74 pKa = 3.89QVLYY78 pKa = 9.18LTSLSQSSFKK88 pKa = 10.71DD89 pKa = 3.63EE90 pKa = 3.87RR91 pKa = 11.84WTLGDD96 pKa = 3.31TSRR99 pKa = 11.84EE100 pKa = 3.9RR101 pKa = 11.84FLTEE105 pKa = 4.38PEE107 pKa = 3.84NCFKK111 pKa = 11.05KK112 pKa = 10.51GGQQIDD118 pKa = 3.52VKK120 pKa = 11.37YY121 pKa = 10.72GGEE124 pKa = 3.66EE125 pKa = 4.1DD126 pKa = 3.92NIVRR130 pKa = 11.84YY131 pKa = 7.1TLWANIYY138 pKa = 8.45FQNEE142 pKa = 3.29QDD144 pKa = 3.29SWEE147 pKa = 4.12KK148 pKa = 11.5AEE150 pKa = 4.59GKK152 pKa = 10.06VDD154 pKa = 3.81NKK156 pKa = 10.77GLYY159 pKa = 10.0YY160 pKa = 10.63EE161 pKa = 5.24DD162 pKa = 4.46ADD164 pKa = 4.04GVRR167 pKa = 11.84TYY169 pKa = 11.24YY170 pKa = 11.02VDD172 pKa = 4.86FIKK175 pKa = 10.67EE176 pKa = 3.87ATKK179 pKa = 10.8YY180 pKa = 10.57SSNGQYY186 pKa = 10.44EE187 pKa = 4.25VLQRR191 pKa = 11.84VNPVSRR197 pKa = 11.84PASGAVNSAPLGCASHH213 pKa = 7.24CSTPKK218 pKa = 10.49KK219 pKa = 9.35KK220 pKa = 8.68TADD223 pKa = 3.31PPRR226 pKa = 11.84RR227 pKa = 11.84GNYY230 pKa = 8.37RR231 pKa = 11.84RR232 pKa = 11.84RR233 pKa = 11.84RR234 pKa = 11.84SKK236 pKa = 10.31PSKK239 pKa = 9.99QGQHH243 pKa = 5.84SPGGRR248 pKa = 11.84QGKK251 pKa = 8.09QASTSRR257 pKa = 11.84PTAPSPGEE265 pKa = 3.67VGRR268 pKa = 11.84SHH270 pKa = 7.37KK271 pKa = 10.47SASPRR276 pKa = 11.84LGGRR280 pKa = 11.84LEE282 pKa = 4.32RR283 pKa = 11.84LIQEE287 pKa = 4.43ARR289 pKa = 11.84DD290 pKa = 3.64PPIVVLKK297 pKa = 11.2GEE299 pKa = 4.4ANPLKK304 pKa = 10.11CLRR307 pKa = 11.84YY308 pKa = 9.55RR309 pKa = 11.84LTKK312 pKa = 10.24GYY314 pKa = 10.49SSTFEE319 pKa = 4.11EE320 pKa = 6.21VSTTWKK326 pKa = 9.3WASCKK331 pKa = 10.12TKK333 pKa = 10.52DD334 pKa = 3.26PCGRR338 pKa = 11.84ARR340 pKa = 11.84MLVSFSTPDD349 pKa = 3.18QRR351 pKa = 11.84DD352 pKa = 3.11LFLQHH357 pKa = 6.24VPLPKK362 pKa = 9.64SVKK365 pKa = 10.26YY366 pKa = 9.74FLGSLNDD373 pKa = 3.34II374 pKa = 4.77

Molecular weight:
42.43 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2335

95

596

333.6

37.48

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.91 ± 0.422

2.313 ± 0.846

6.253 ± 0.41

6.039 ± 0.486

4.625 ± 0.562

6.124 ± 0.662

2.184 ± 0.185

3.897 ± 0.689

5.61 ± 0.712

9.208 ± 0.886

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.413 ± 0.324

4.197 ± 0.667

6.51 ± 1.099

4.754 ± 0.374

6.124 ± 0.694

8.051 ± 0.689

6.253 ± 0.489

6.296 ± 0.812

1.285 ± 0.392

2.955 ± 0.367

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski