Human papillomavirus 29

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 2

Average proteome isoelectric point is 6.86

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 8 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P50792|VL1_HPV29 Major capsid protein L1 OS=Human papillomavirus 29 OX=37112 GN=L1 PE=3 SV=1
MM1 pKa = 7.64HH2 pKa = 7.27GPKK5 pKa = 8.86PTVKK9 pKa = 10.55DD10 pKa = 3.43IEE12 pKa = 5.35LDD14 pKa = 3.73LAPEE18 pKa = 4.42AVPLVCNEE26 pKa = 4.0QLDD29 pKa = 4.02SSDD32 pKa = 4.49EE33 pKa = 4.01EE34 pKa = 4.32DD35 pKa = 4.89CIDD38 pKa = 3.72VVEE41 pKa = 4.82PAQQAYY47 pKa = 9.27RR48 pKa = 11.84VVTLCTKK55 pKa = 10.59CSTTLRR61 pKa = 11.84LVVEE65 pKa = 4.39SSEE68 pKa = 3.8ADD70 pKa = 2.74IRR72 pKa = 11.84AFQEE76 pKa = 3.8LLLRR80 pKa = 11.84TLKK83 pKa = 10.26IVCPRR88 pKa = 11.84CAA90 pKa = 3.54

Molecular weight: 9.97 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P51897|VE4_HPV29 Protein E4 OS=Human papillomavirus 29 OX=37112 GN=E4 PE=3 SV=2
MM1 pKa = 7.95ADD3 pKa = 3.07NSAHH7 pKa = 6.67KK8 pKa = 10.15KK9 pKa = 10.46YY10 pKa = 10.21PLLDD14 pKa = 4.55LYY16 pKa = 10.15TPPTTPPARR25 pKa = 11.84PPKK28 pKa = 9.52PRR30 pKa = 11.84WGLRR34 pKa = 11.84RR35 pKa = 11.84DD36 pKa = 3.6RR37 pKa = 11.84NGNDD41 pKa = 3.13AGLKK45 pKa = 9.79QSGLGHH51 pKa = 6.34SSSSSSSTSSSSSNRR66 pKa = 11.84PRR68 pKa = 11.84PTPPPRR74 pKa = 11.84KK75 pKa = 8.45PVHH78 pKa = 6.01EE79 pKa = 5.42RR80 pKa = 11.84VDD82 pKa = 3.25QWTVTGPGTVTLQVKK97 pKa = 8.38TPTGTQVILTVHH109 pKa = 6.67LL110 pKa = 4.21

Molecular weight: 11.9 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8

0

8

2560

90

660

320.0

35.74

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.172 ± 0.269

2.656 ± 0.714

5.742 ± 0.462

5.664 ± 0.883

3.281 ± 0.499

7.031 ± 0.623

2.305 ± 0.377

3.633 ± 0.449

4.688 ± 0.632

7.813 ± 0.582

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.875 ± 0.246

3.125 ± 0.441

7.109 ± 1.126

5.117 ± 1.162

6.328 ± 0.48

7.539 ± 0.378

7.539 ± 1.159

7.07 ± 0.606

1.641 ± 0.278

3.672 ± 0.278
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski