Human papillomavirus 31

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 9

Average proteome isoelectric point is 6.97

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 9 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P17388|VL1_HPV31 Major capsid protein L1 OS=Human papillomavirus 31 OX=10585 GN=L1 PE=3 SV=1
MM1 pKa = 7.69RR2 pKa = 11.84GEE4 pKa = 4.29TPTLQDD10 pKa = 3.63YY11 pKa = 11.26VLDD14 pKa = 4.34LQPEE18 pKa = 4.33ATDD21 pKa = 3.2LHH23 pKa = 8.23CYY25 pKa = 8.12EE26 pKa = 4.67QLPDD30 pKa = 3.69SSDD33 pKa = 3.54EE34 pKa = 4.06EE35 pKa = 4.5DD36 pKa = 5.04VIDD39 pKa = 4.58SPAGQAEE46 pKa = 4.66PDD48 pKa = 3.34TSNYY52 pKa = 10.56NIVTFCCQCKK62 pKa = 8.79STLRR66 pKa = 11.84LCVQSTQVDD75 pKa = 3.23IRR77 pKa = 11.84ILQEE81 pKa = 3.71LLMGSFGIVCPNCSTRR97 pKa = 11.84LL98 pKa = 3.52

Molecular weight: 10.92 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P17382|VE1_HPV31 Replication protein E1 OS=Human papillomavirus 31 OX=10585 GN=E1 PE=3 SV=1
MM1 pKa = 7.97AILKK5 pKa = 8.26WKK7 pKa = 9.46RR8 pKa = 11.84SRR10 pKa = 11.84WYY12 pKa = 10.55SSDD15 pKa = 3.49EE16 pKa = 3.64ISFAGIVTKK25 pKa = 10.84LPTANNTTTSNSKK38 pKa = 8.32TCALGTSEE46 pKa = 4.19GVRR49 pKa = 11.84RR50 pKa = 11.84ATTSTKK56 pKa = 10.25RR57 pKa = 11.84PRR59 pKa = 11.84TEE61 pKa = 3.66PEE63 pKa = 3.66HH64 pKa = 7.13RR65 pKa = 11.84NTHH68 pKa = 5.97HH69 pKa = 6.85PNKK72 pKa = 10.03LLRR75 pKa = 11.84GDD77 pKa = 3.86SVDD80 pKa = 3.63SVNCGVISAAACTNQTRR97 pKa = 11.84AVSCPATTPIIHH109 pKa = 6.96LKK111 pKa = 10.46GDD113 pKa = 3.83ANILKK118 pKa = 9.85CLRR121 pKa = 11.84YY122 pKa = 9.59RR123 pKa = 11.84LSKK126 pKa = 10.72YY127 pKa = 8.93KK128 pKa = 10.22QLYY131 pKa = 8.14EE132 pKa = 4.15QVSSTWHH139 pKa = 4.39WTCTDD144 pKa = 3.55GKK146 pKa = 9.52HH147 pKa = 5.91KK148 pKa = 10.72NAIVTLTYY156 pKa = 10.47ISTSQRR162 pKa = 11.84DD163 pKa = 3.63DD164 pKa = 3.61FLNTVKK170 pKa = 10.39IPNTVSVSTGYY181 pKa = 7.77MTII184 pKa = 3.68

Molecular weight: 20.47 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9

0

9

2585

84

629

287.2

32.11

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.764 ± 0.463

3.172 ± 0.674

5.261 ± 0.541

4.72 ± 0.567

3.791 ± 0.545

5.571 ± 0.45

2.476 ± 0.402

5.377 ± 0.537

5.455 ± 0.768

8.162 ± 0.827

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.896 ± 0.306

4.565 ± 0.57

5.841 ± 1.094

3.985 ± 0.51

4.758 ± 0.469

8.24 ± 0.705

9.091 ± 1.075

6.576 ± 0.502

1.393 ± 0.311

3.907 ± 0.212
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski