Amino acid dipepetide frequency for Cariama cristata (Red-legged seriema)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.525AlaAla: 5.525 ± 0.052	1.284AlaCys: 1.284 ± 0.024	2.997AlaAsp: 2.997 ± 0.029	4.544AlaGlu: 4.544 ± 0.038	2.591AlaPhe: 2.591 ± 0.029	3.81AlaGly: 3.81 ± 0.035	1.355AlaHis: 1.355 ± 0.021	3.128AlaIle: 3.128 ± 0.028	3.759AlaLys: 3.759 ± 0.04	6.376AlaLeu: 6.376 ± 0.057	1.518AlaMet: 1.518 ± 0.021	2.245AlaAsn: 2.245 ± 0.023	2.834AlaPro: 2.834 ± 0.036	2.686AlaGln: 2.686 ± 0.033	2.902AlaArg: 2.902 ± 0.033	5.156AlaSer: 5.156 ± 0.042	3.372AlaThr: 3.372 ± 0.034	4.841AlaVal: 4.841 ± 0.04	0.673AlaTrp: 0.673 ± 0.013	1.68AlaTyr: 1.68 ± 0.02	0.001AlaXaa: 0.001 ± 0.0
Cys	1.165CysAla: 1.165 ± 0.021	0.676CysCys: 0.676 ± 0.018	1.05CysAsp: 1.05 ± 0.024	1.314CysGlu: 1.314 ± 0.029	0.931CysPhe: 0.931 ± 0.018	1.423CysGly: 1.423 ± 0.023	0.636CysHis: 0.636 ± 0.014	1.16CysIle: 1.16 ± 0.021	1.371CysLys: 1.371 ± 0.022	2.168CysLeu: 2.168 ± 0.03	0.471CysMet: 0.471 ± 0.011	0.929CysAsn: 0.929 ± 0.019	1.218CysPro: 1.218 ± 0.028	1.033CysGln: 1.033 ± 0.021	1.247CysArg: 1.247 ± 0.023	2.007CysSer: 2.007 ± 0.034	1.196CysThr: 1.196 ± 0.024	1.326CysVal: 1.326 ± 0.022	0.297CysTrp: 0.297 ± 0.009	0.683CysTyr: 0.683 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	2.891AspAla: 2.891 ± 0.027	1.127AspCys: 1.127 ± 0.022	2.846AspAsp: 2.846 ± 0.037	3.714AspGlu: 3.714 ± 0.042	2.276AspPhe: 2.276 ± 0.026	3.274AspGly: 3.274 ± 0.042	1.188AspHis: 1.188 ± 0.02	2.968AspIle: 2.968 ± 0.03	2.851AspLys: 2.851 ± 0.032	5.066AspLeu: 5.066 ± 0.043	1.166AspMet: 1.166 ± 0.018	2.003AspAsn: 2.003 ± 0.029	2.634AspPro: 2.634 ± 0.035	1.874AspGln: 1.874 ± 0.026	2.361AspArg: 2.361 ± 0.029	4.151AspSer: 4.151 ± 0.04	2.548AspThr: 2.548 ± 0.024	3.264AspVal: 3.264 ± 0.031	0.653AspTrp: 0.653 ± 0.015	1.659AspTyr: 1.659 ± 0.023	0.0AspXaa: 0.0 ± 0.0
Glu	4.645GluAla: 4.645 ± 0.04	1.321GluCys: 1.321 ± 0.03	4.574GluAsp: 4.574 ± 0.036	8.014GluGlu: 8.014 ± 0.094	2.268GluPhe: 2.268 ± 0.026	3.925GluGly: 3.925 ± 0.042	1.538GluHis: 1.538 ± 0.022	3.635GluIle: 3.635 ± 0.034	5.847GluLys: 5.847 ± 0.063	6.371GluLeu: 6.371 ± 0.06	1.81GluMet: 1.81 ± 0.024	3.559GluAsn: 3.559 ± 0.036	2.539GluPro: 2.539 ± 0.03	3.256GluGln: 3.256 ± 0.038	3.919GluArg: 3.919 ± 0.051	4.545GluSer: 4.545 ± 0.042	3.608GluThr: 3.608 ± 0.037	4.379GluVal: 4.379 ± 0.038	0.73GluTrp: 0.73 ± 0.014	1.849GluTyr: 1.849 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	2.184PheAla: 2.184 ± 0.025	1.016PheCys: 1.016 ± 0.02	1.861PheAsp: 1.861 ± 0.022	2.168PheGlu: 2.168 ± 0.026	1.856PhePhe: 1.856 ± 0.03	2.321PheGly: 2.321 ± 0.031	1.084PheHis: 1.084 ± 0.016	2.16PheIle: 2.16 ± 0.03	2.048PheLys: 2.048 ± 0.025	4.268PheLeu: 4.268 ± 0.042	0.818PheMet: 0.818 ± 0.016	1.565PheAsn: 1.565 ± 0.021	1.943PhePro: 1.943 ± 0.023	1.83PheGln: 1.83 ± 0.023	1.924PheArg: 1.924 ± 0.025	3.5PheSer: 3.5 ± 0.037	2.267PheThr: 2.267 ± 0.026	2.405PheVal: 2.405 ± 0.033	0.518PheTrp: 0.518 ± 0.014	1.393PheTyr: 1.393 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	3.344GlyAla: 3.344 ± 0.037	1.234GlyCys: 1.234 ± 0.027	2.921GlyAsp: 2.921 ± 0.037	3.802GlyGlu: 3.802 ± 0.045	2.501GlyPhe: 2.501 ± 0.031	3.797GlyGly: 3.797 ± 0.059	1.494GlyHis: 1.494 ± 0.022	3.149GlyIle: 3.149 ± 0.036	4.087GlyLys: 4.087 ± 0.044	5.152GlyLeu: 5.152 ± 0.054	1.371GlyMet: 1.371 ± 0.021	2.6GlyAsn: 2.6 ± 0.03	2.716GlyPro: 2.716 ± 0.073	2.518GlyGln: 2.518 ± 0.034	3.136GlyArg: 3.136 ± 0.038	5.014GlySer: 5.014 ± 0.048	3.444GlyThr: 3.444 ± 0.039	3.439GlyVal: 3.439 ± 0.04	0.752GlyTrp: 0.752 ± 0.02	1.924GlyTyr: 1.924 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	1.321HisAla: 1.321 ± 0.019	0.719HisCys: 0.719 ± 0.017	0.917HisAsp: 0.917 ± 0.016	1.386HisGlu: 1.386 ± 0.021	1.08HisPhe: 1.08 ± 0.019	1.448HisGly: 1.448 ± 0.022	0.862HisHis: 0.862 ± 0.021	1.353HisIle: 1.353 ± 0.02	1.386HisLys: 1.386 ± 0.024	2.814HisLeu: 2.814 ± 0.028	0.581HisMet: 0.581 ± 0.013	0.995HisAsn: 0.995 ± 0.017	1.45HisPro: 1.45 ± 0.022	1.17HisGln: 1.17 ± 0.022	1.436HisArg: 1.436 ± 0.022	2.205HisSer: 2.205 ± 0.031	1.31HisThr: 1.31 ± 0.02	1.54HisVal: 1.54 ± 0.02	0.345HisTrp: 0.345 ± 0.01	0.865HisTyr: 0.865 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	3.076IleAla: 3.076 ± 0.031	1.235IleCys: 1.235 ± 0.02	2.389IleAsp: 2.389 ± 0.031	2.969IleGlu: 2.969 ± 0.032	2.245IlePhe: 2.245 ± 0.032	2.54IleGly: 2.54 ± 0.03	1.424IleHis: 1.424 ± 0.021	2.787IleIle: 2.787 ± 0.034	3.124IleLys: 3.124 ± 0.034	5.058IleLeu: 5.058 ± 0.045	1.097IleMet: 1.097 ± 0.019	2.244IleAsn: 2.244 ± 0.025	2.88IlePro: 2.88 ± 0.033	2.481IleGln: 2.481 ± 0.028	2.53IleArg: 2.53 ± 0.025	4.204IleSer: 4.204 ± 0.033	2.939IleThr: 2.939 ± 0.033	3.007IleVal: 3.007 ± 0.03	0.594IleTrp: 0.594 ± 0.014	1.662IleTyr: 1.662 ± 0.022	0.001IleXaa: 0.001 ± 0.0
Lys	4.105LysAla: 4.105 ± 0.042	1.277LysCys: 1.277 ± 0.02	3.536LysAsp: 3.536 ± 0.038	5.813LysGlu: 5.813 ± 0.07	1.946LysPhe: 1.946 ± 0.026	3.547LysGly: 3.547 ± 0.051	1.587LysHis: 1.587 ± 0.022	3.311LysIle: 3.311 ± 0.034	5.478LysLys: 5.478 ± 0.069	5.815LysLeu: 5.815 ± 0.049	1.582LysMet: 1.582 ± 0.02	2.869LysAsn: 2.869 ± 0.032	3.137LysPro: 3.137 ± 0.035	3.02LysGln: 3.02 ± 0.037	3.57LysArg: 3.57 ± 0.041	4.374LysSer: 4.374 ± 0.046	3.468LysThr: 3.468 ± 0.032	3.768LysVal: 3.768 ± 0.033	0.682LysTrp: 0.682 ± 0.014	1.928LysTyr: 1.928 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	6.181LeuAla: 6.181 ± 0.055	2.169LeuCys: 2.169 ± 0.029	4.828LeuAsp: 4.828 ± 0.039	7.052LeuGlu: 7.052 ± 0.066	3.611LeuPhe: 3.611 ± 0.04	5.175LeuGly: 5.175 ± 0.043	2.654LeuHis: 2.654 ± 0.031	4.302LeuIle: 4.302 ± 0.039	6.504LeuLys: 6.504 ± 0.053	10.017LeuLeu: 10.017 ± 0.081	2.052LeuMet: 2.052 ± 0.022	3.948LeuAsn: 3.948 ± 0.035	5.359LeuPro: 5.359 ± 0.047	5.63LeuGln: 5.63 ± 0.051	5.116LeuArg: 5.116 ± 0.046	7.809LeuSer: 7.809 ± 0.06	5.016LeuThr: 5.016 ± 0.038	5.483LeuVal: 5.483 ± 0.042	1.076LeuTrp: 1.076 ± 0.016	2.817LeuTyr: 2.817 ± 0.035	0.001LeuXaa: 0.001 ± 0.0
Met	1.634MetAla: 1.634 ± 0.02	0.434MetCys: 0.434 ± 0.012	1.305MetAsp: 1.305 ± 0.02	1.897MetGlu: 1.897 ± 0.024	0.861MetPhe: 0.861 ± 0.018	1.267MetGly: 1.267 ± 0.019	0.529MetHis: 0.529 ± 0.012	1.014MetIle: 1.014 ± 0.019	1.658MetLys: 1.658 ± 0.025	2.072MetLeu: 2.072 ± 0.027	0.615MetMet: 0.615 ± 0.012	1.003MetAsn: 1.003 ± 0.017	1.066MetPro: 1.066 ± 0.018	1.058MetGln: 1.058 ± 0.018	1.039MetArg: 1.039 ± 0.017	1.56MetSer: 1.56 ± 0.02	1.171MetThr: 1.171 ± 0.019	1.446MetVal: 1.446 ± 0.018	0.248MetTrp: 0.248 ± 0.008	0.677MetTyr: 0.677 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.393AsnAla: 2.393 ± 0.027	1.002AsnCys: 1.002 ± 0.02	1.778AsnAsp: 1.778 ± 0.025	2.665AsnGlu: 2.665 ± 0.031	1.666AsnPhe: 1.666 ± 0.023	2.791AsnGly: 2.791 ± 0.04	1.014AsnHis: 1.014 ± 0.017	2.583AsnIle: 2.583 ± 0.027	2.672AsnLys: 2.672 ± 0.033	4.155AsnLeu: 4.155 ± 0.037	1.013AsnMet: 1.013 ± 0.018	1.875AsnAsn: 1.875 ± 0.026	2.303AsnPro: 2.303 ± 0.026	1.745AsnGln: 1.745 ± 0.026	2.028AsnArg: 2.028 ± 0.024	3.557AsnSer: 3.557 ± 0.035	2.302AsnThr: 2.302 ± 0.028	2.554AsnVal: 2.554 ± 0.024	0.515AsnTrp: 0.515 ± 0.014	1.327AsnTyr: 1.327 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	3.587ProAla: 3.587 ± 0.041	1.022ProCys: 1.022 ± 0.024	2.614ProAsp: 2.614 ± 0.027	3.854ProGlu: 3.854 ± 0.036	1.916ProPhe: 1.916 ± 0.025	3.66ProGly: 3.66 ± 0.105	1.223ProHis: 1.223 ± 0.019	2.003ProIle: 2.003 ± 0.025	2.774ProLys: 2.774 ± 0.032	4.617ProLeu: 4.617 ± 0.037	0.948ProMet: 0.948 ± 0.018	1.953ProAsn: 1.953 ± 0.028	4.189ProPro: 4.189 ± 0.073	2.324ProGln: 2.324 ± 0.03	2.422ProArg: 2.422 ± 0.032	4.875ProSer: 4.875 ± 0.056	2.698ProThr: 2.698 ± 0.033	3.725ProVal: 3.725 ± 0.04	0.546ProTrp: 0.546 ± 0.015	1.488ProTyr: 1.488 ± 0.024	0.001ProXaa: 0.001 ± 0.001
Gln	2.984GlnAla: 2.984 ± 0.037	0.973GlnCys: 0.973 ± 0.022	2.248GlnAsp: 2.248 ± 0.024	3.715GlnGlu: 3.715 ± 0.05	1.468GlnPhe: 1.468 ± 0.019	2.447GlnGly: 2.447 ± 0.032	1.265GlnHis: 1.265 ± 0.021	2.275GlnIle: 2.275 ± 0.028	3.272GlnLys: 3.272 ± 0.038	4.607GlnLeu: 4.607 ± 0.045	1.12GlnMet: 1.12 ± 0.02	2.087GlnAsn: 2.087 ± 0.029	2.339GlnPro: 2.339 ± 0.04	3.033GlnGln: 3.033 ± 0.071	2.622GlnArg: 2.622 ± 0.034	3.222GlnSer: 3.222 ± 0.035	2.397GlnThr: 2.397 ± 0.026	2.751GlnVal: 2.751 ± 0.033	0.515GlnTrp: 0.515 ± 0.012	1.301GlnTyr: 1.301 ± 0.019	0.001GlnXaa: 0.001 ± 0.001
Arg	2.983ArgAla: 2.983 ± 0.033	1.108ArgCys: 1.108 ± 0.023	2.574ArgAsp: 2.574 ± 0.03	3.729ArgGlu: 3.729 ± 0.046	1.904ArgPhe: 1.904 ± 0.023	2.831ArgGly: 2.831 ± 0.039	1.434ArgHis: 1.434 ± 0.02	2.635ArgIle: 2.635 ± 0.031	3.939ArgLys: 3.939 ± 0.048	4.763ArgLeu: 4.763 ± 0.044	1.187ArgMet: 1.187 ± 0.018	2.274ArgAsn: 2.274 ± 0.023	2.348ArgPro: 2.348 ± 0.027	2.472ArgGln: 2.472 ± 0.029	3.607ArgArg: 3.607 ± 0.047	3.95ArgSer: 3.95 ± 0.053	2.692ArgThr: 2.692 ± 0.031	2.873ArgVal: 2.873 ± 0.032	0.618ArgTrp: 0.618 ± 0.012	1.585ArgTyr: 1.585 ± 0.021	0.0ArgXaa: 0.0 ± 0.0
Ser	5.126SerAla: 5.126 ± 0.044	1.824SerCys: 1.824 ± 0.029	4.085SerAsp: 4.085 ± 0.038	5.201SerGlu: 5.201 ± 0.049	3.196SerPhe: 3.196 ± 0.032	4.913SerGly: 4.913 ± 0.045	2.021SerHis: 2.021 ± 0.027	3.651SerIle: 3.651 ± 0.034	4.557SerLys: 4.557 ± 0.049	7.96SerLeu: 7.96 ± 0.056	1.626SerMet: 1.626 ± 0.019	3.158SerAsn: 3.158 ± 0.035	5.124SerPro: 5.124 ± 0.066	3.659SerGln: 3.659 ± 0.038	4.083SerArg: 4.083 ± 0.048	9.253SerSer: 9.253 ± 0.099	4.617SerThr: 4.617 ± 0.043	5.182SerVal: 5.182 ± 0.044	0.955SerTrp: 0.955 ± 0.016	2.301SerTyr: 2.301 ± 0.028	0.001SerXaa: 0.001 ± 0.0
Thr	3.834ThrAla: 3.834 ± 0.036	1.304ThrCys: 1.304 ± 0.025	2.761ThrAsp: 2.761 ± 0.029	3.853ThrGlu: 3.853 ± 0.038	2.219ThrPhe: 2.219 ± 0.028	3.468ThrGly: 3.468 ± 0.039	1.189ThrHis: 1.189 ± 0.019	2.653ThrIle: 2.653 ± 0.032	2.949ThrLys: 2.949 ± 0.03	5.16ThrLeu: 5.16 ± 0.039	1.148ThrMet: 1.148 ± 0.018	2.018ThrAsn: 2.018 ± 0.027	3.16ThrPro: 3.16 ± 0.04	2.146ThrGln: 2.146 ± 0.025	2.292ThrArg: 2.292 ± 0.026	4.733ThrSer: 4.733 ± 0.043	3.09ThrThr: 3.09 ± 0.038	4.167ThrVal: 4.167 ± 0.043	0.68ThrTrp: 0.68 ± 0.015	1.597ThrTyr: 1.597 ± 0.023	0.001ThrXaa: 0.001 ± 0.0
Val	4.04ValAla: 4.04 ± 0.034	1.525ValCys: 1.525 ± 0.027	3.07ValAsp: 3.07 ± 0.031	3.993ValGlu: 3.993 ± 0.035	2.681ValPhe: 2.681 ± 0.035	3.337ValGly: 3.337 ± 0.039	1.565ValHis: 1.565 ± 0.019	3.375ValIle: 3.375 ± 0.034	3.923ValLys: 3.923 ± 0.033	6.238ValLeu: 6.238 ± 0.051	1.436ValMet: 1.436 ± 0.021	2.652ValAsn: 2.652 ± 0.03	3.412ValPro: 3.412 ± 0.034	2.813ValGln: 2.813 ± 0.035	2.906ValArg: 2.906 ± 0.032	5.034ValSer: 5.034 ± 0.041	3.948ValThr: 3.948 ± 0.042	4.24ValVal: 4.24 ± 0.045	0.703ValTrp: 0.703 ± 0.016	1.937ValTyr: 1.937 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	0.659TrpAla: 0.659 ± 0.015	0.249TrpCys: 0.249 ± 0.01	0.67TrpAsp: 0.67 ± 0.016	0.773TrpGlu: 0.773 ± 0.015	0.462TrpPhe: 0.462 ± 0.011	0.628TrpGly: 0.628 ± 0.018	0.306TrpHis: 0.306 ± 0.01	0.646TrpIle: 0.646 ± 0.015	0.898TrpLys: 0.898 ± 0.015	1.183TrpLeu: 1.183 ± 0.02	0.305TrpMet: 0.305 ± 0.01	0.613TrpAsn: 0.613 ± 0.014	0.413TrpPro: 0.413 ± 0.011	0.537TrpGln: 0.537 ± 0.013	0.625TrpArg: 0.625 ± 0.013	0.867TrpSer: 0.867 ± 0.016	0.646TrpThr: 0.646 ± 0.014	0.653TrpVal: 0.653 ± 0.015	0.198TrpTrp: 0.198 ± 0.007	0.379TrpTyr: 0.379 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.602TyrAla: 1.602 ± 0.023	0.799TyrCys: 0.799 ± 0.016	1.489TyrAsp: 1.489 ± 0.023	1.877TyrGlu: 1.877 ± 0.027	1.453TyrPhe: 1.453 ± 0.026	1.794TyrGly: 1.794 ± 0.025	0.815TyrHis: 0.815 ± 0.015	1.698TyrIle: 1.698 ± 0.022	1.718TyrLys: 1.718 ± 0.022	2.941TyrLeu: 2.941 ± 0.031	0.691TyrMet: 0.691 ± 0.016	1.345TyrAsn: 1.345 ± 0.022	1.374TyrPro: 1.374 ± 0.022	1.357TyrGln: 1.357 ± 0.02	1.739TyrArg: 1.739 ± 0.022	2.475TyrSer: 2.475 ± 0.03	1.694TyrThr: 1.694 ± 0.022	1.785TyrVal: 1.785 ± 0.027	0.409TyrTrp: 0.409 ± 0.012	1.146TyrTyr: 1.146 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.001	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.035XaaXaa: 0.035 ± 0.007

Statistics based on 8694 proteins (3715725 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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