Amino acid dipepetide frequency for Colletotrichum salicis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.463AlaAla: 10.463 ± 0.072	1.108AlaCys: 1.108 ± 0.014	4.607AlaAsp: 4.607 ± 0.028	5.286AlaGlu: 5.286 ± 0.046	3.256AlaPhe: 3.256 ± 0.023	6.348AlaGly: 6.348 ± 0.04	1.748AlaHis: 1.748 ± 0.02	4.302AlaIle: 4.302 ± 0.028	4.308AlaLys: 4.308 ± 0.034	7.751AlaLeu: 7.751 ± 0.037	2.104AlaMet: 2.104 ± 0.02	3.134AlaAsn: 3.134 ± 0.023	5.254AlaPro: 5.254 ± 0.049	3.433AlaGln: 3.433 ± 0.03	4.838AlaArg: 4.838 ± 0.032	7.59AlaSer: 7.59 ± 0.04	5.704AlaThr: 5.704 ± 0.034	5.847AlaVal: 5.847 ± 0.035	1.278AlaTrp: 1.278 ± 0.018	2.219AlaTyr: 2.219 ± 0.022	0.002AlaXaa: 0.002 ± 0.001
Cys	0.957CysAla: 0.957 ± 0.013	0.253CysCys: 0.253 ± 0.007	0.668CysAsp: 0.668 ± 0.01	0.573CysGlu: 0.573 ± 0.011	0.547CysPhe: 0.547 ± 0.009	0.985CysGly: 0.985 ± 0.017	0.322CysHis: 0.322 ± 0.007	0.674CysIle: 0.674 ± 0.01	0.509CysLys: 0.509 ± 0.01	1.209CysLeu: 1.209 ± 0.016	0.269CysMet: 0.269 ± 0.008	0.449CysAsn: 0.449 ± 0.009	0.677CysPro: 0.677 ± 0.014	0.448CysGln: 0.448 ± 0.008	0.74CysArg: 0.74 ± 0.012	0.905CysSer: 0.905 ± 0.015	0.695CysThr: 0.695 ± 0.012	0.806CysVal: 0.806 ± 0.012	0.215CysTrp: 0.215 ± 0.005	0.34CysTyr: 0.34 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.005AspAla: 5.005 ± 0.034	0.641AspCys: 0.641 ± 0.011	4.455AspAsp: 4.455 ± 0.038	4.437AspGlu: 4.437 ± 0.037	2.333AspPhe: 2.333 ± 0.019	4.311AspGly: 4.311 ± 0.032	1.214AspHis: 1.214 ± 0.015	2.937AspIle: 2.937 ± 0.026	2.459AspLys: 2.459 ± 0.021	4.937AspLeu: 4.937 ± 0.029	1.272AspMet: 1.272 ± 0.015	1.898AspAsn: 1.898 ± 0.019	3.244AspPro: 3.244 ± 0.023	1.816AspGln: 1.816 ± 0.016	2.954AspArg: 2.954 ± 0.026	3.974AspSer: 3.974 ± 0.027	2.917AspThr: 2.917 ± 0.023	3.835AspVal: 3.835 ± 0.027	0.941AspTrp: 0.941 ± 0.012	1.577AspTyr: 1.577 ± 0.016	0.001AspXaa: 0.001 ± 0.0
Glu	5.662GluAla: 5.662 ± 0.038	0.592GluCys: 0.592 ± 0.01	4.154GluAsp: 4.154 ± 0.033	5.314GluGlu: 5.314 ± 0.057	1.903GluPhe: 1.903 ± 0.018	3.798GluGly: 3.798 ± 0.026	1.338GluHis: 1.338 ± 0.017	2.88GluIle: 2.88 ± 0.024	3.672GluLys: 3.672 ± 0.032	4.854GluLeu: 4.854 ± 0.032	1.454GluMet: 1.454 ± 0.015	2.165GluAsn: 2.165 ± 0.018	2.833GluPro: 2.833 ± 0.036	2.23GluGln: 2.23 ± 0.022	3.659GluArg: 3.659 ± 0.029	4.106GluSer: 4.106 ± 0.028	3.5GluThr: 3.5 ± 0.031	3.674GluVal: 3.674 ± 0.029	0.88GluTrp: 0.88 ± 0.012	1.588GluTyr: 1.588 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	3.187PheAla: 3.187 ± 0.025	0.569PheCys: 0.569 ± 0.011	2.362PheAsp: 2.362 ± 0.018	2.129PheGlu: 2.129 ± 0.019	1.675PhePhe: 1.675 ± 0.021	3.01PheGly: 3.01 ± 0.025	0.891PheHis: 0.891 ± 0.014	1.799PheIle: 1.799 ± 0.02	1.552PheLys: 1.552 ± 0.016	3.423PheLeu: 3.423 ± 0.024	0.817PheMet: 0.817 ± 0.011	1.492PheAsn: 1.492 ± 0.016	1.974PhePro: 1.974 ± 0.017	1.374PheGln: 1.374 ± 0.018	1.924PheArg: 1.924 ± 0.016	3.01PheSer: 3.01 ± 0.023	2.216PheThr: 2.216 ± 0.022	2.441PheVal: 2.441 ± 0.023	0.673PheTrp: 0.673 ± 0.01	1.116PheTyr: 1.116 ± 0.014	0.001PheXaa: 0.001 ± 0.0
Gly	5.884GlyAla: 5.884 ± 0.04	0.938GlyCys: 0.938 ± 0.014	3.771GlyAsp: 3.771 ± 0.027	3.605GlyGlu: 3.605 ± 0.029	2.958GlyPhe: 2.958 ± 0.025	6.641GlyGly: 6.641 ± 0.065	1.715GlyHis: 1.715 ± 0.018	3.594GlyIle: 3.594 ± 0.026	3.476GlyLys: 3.476 ± 0.026	6.198GlyLeu: 6.198 ± 0.036	1.674GlyMet: 1.674 ± 0.016	2.704GlyAsn: 2.704 ± 0.023	3.543GlyPro: 3.543 ± 0.033	2.596GlyGln: 2.596 ± 0.02	4.137GlyArg: 4.137 ± 0.032	5.859GlySer: 5.859 ± 0.042	4.278GlyThr: 4.278 ± 0.046	4.58GlyVal: 4.58 ± 0.034	1.214GlyTrp: 1.214 ± 0.014	2.138GlyTyr: 2.138 ± 0.018	0.001GlyXaa: 0.001 ± 0.0
His	1.823HisAla: 1.823 ± 0.017	0.335HisCys: 0.335 ± 0.007	1.28HisAsp: 1.28 ± 0.014	1.27HisGlu: 1.27 ± 0.017	0.918HisPhe: 0.918 ± 0.011	1.7HisGly: 1.7 ± 0.019	0.869HisHis: 0.869 ± 0.015	1.136HisIle: 1.136 ± 0.014	0.894HisLys: 0.894 ± 0.011	2.164HisLeu: 2.164 ± 0.022	0.512HisMet: 0.512 ± 0.01	0.841HisAsn: 0.841 ± 0.013	1.593HisPro: 1.593 ± 0.019	0.99HisGln: 0.99 ± 0.014	1.489HisArg: 1.489 ± 0.016	1.688HisSer: 1.688 ± 0.019	1.216HisThr: 1.216 ± 0.014	1.427HisVal: 1.427 ± 0.015	0.35HisTrp: 0.35 ± 0.009	0.662HisTyr: 0.662 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	4.229IleAla: 4.229 ± 0.03	0.703IleCys: 0.703 ± 0.012	2.805IleAsp: 2.805 ± 0.024	2.742IleGlu: 2.742 ± 0.021	1.967IlePhe: 1.967 ± 0.018	3.255IleGly: 3.255 ± 0.025	1.148IleHis: 1.148 ± 0.014	2.502IleIle: 2.502 ± 0.025	2.166IleLys: 2.166 ± 0.018	4.352IleLeu: 4.352 ± 0.029	1.038IleMet: 1.038 ± 0.014	1.772IleAsn: 1.772 ± 0.017	2.936IlePro: 2.936 ± 0.022	1.786IleGln: 1.786 ± 0.014	2.656IleArg: 2.656 ± 0.021	3.621IleSer: 3.621 ± 0.025	2.845IleThr: 2.845 ± 0.025	3.196IleVal: 3.196 ± 0.024	0.744IleTrp: 0.744 ± 0.013	1.32IleTyr: 1.32 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.464LysAla: 4.464 ± 0.032	0.497LysCys: 0.497 ± 0.01	2.84LysAsp: 2.84 ± 0.023	3.308LysGlu: 3.308 ± 0.026	1.507LysPhe: 1.507 ± 0.015	3.032LysGly: 3.032 ± 0.022	1.098LysHis: 1.098 ± 0.015	2.195LysIle: 2.195 ± 0.022	3.378LysLys: 3.378 ± 0.045	3.974LysLeu: 3.974 ± 0.029	1.05LysMet: 1.05 ± 0.013	1.74LysAsn: 1.74 ± 0.016	2.746LysPro: 2.746 ± 0.026	1.763LysGln: 1.763 ± 0.019	3.186LysArg: 3.186 ± 0.028	3.477LysSer: 3.477 ± 0.027	2.993LysThr: 2.993 ± 0.024	2.893LysVal: 2.893 ± 0.023	0.69LysTrp: 0.69 ± 0.01	1.34LysTyr: 1.34 ± 0.015	0.001LysXaa: 0.001 ± 0.0
Leu	8.012LeuAla: 8.012 ± 0.039	1.168LeuCys: 1.168 ± 0.015	4.947LeuAsp: 4.947 ± 0.033	5.243LeuGlu: 5.243 ± 0.042	3.236LeuPhe: 3.236 ± 0.026	6.061LeuGly: 6.061 ± 0.031	2.083LeuHis: 2.083 ± 0.02	3.754LeuIle: 3.754 ± 0.026	4.052LeuLys: 4.052 ± 0.028	7.995LeuLeu: 7.995 ± 0.055	1.775LeuMet: 1.775 ± 0.02	3.061LeuAsn: 3.061 ± 0.024	5.483LeuPro: 5.483 ± 0.049	3.543LeuGln: 3.543 ± 0.027	5.496LeuArg: 5.496 ± 0.032	6.909LeuSer: 6.909 ± 0.037	4.908LeuThr: 4.908 ± 0.041	5.441LeuVal: 5.441 ± 0.032	1.225LeuTrp: 1.225 ± 0.015	2.246LeuTyr: 2.246 ± 0.019	0.001LeuXaa: 0.001 ± 0.0
Met	2.37MetAla: 2.37 ± 0.021	0.254MetCys: 0.254 ± 0.007	1.223MetAsp: 1.223 ± 0.015	1.277MetGlu: 1.277 ± 0.013	0.776MetPhe: 0.776 ± 0.011	1.551MetGly: 1.551 ± 0.016	0.461MetHis: 0.461 ± 0.009	0.992MetIle: 0.992 ± 0.012	1.044MetLys: 1.044 ± 0.013	1.835MetLeu: 1.835 ± 0.017	0.621MetMet: 0.621 ± 0.011	0.82MetAsn: 0.82 ± 0.011	1.347MetPro: 1.347 ± 0.017	0.824MetGln: 0.824 ± 0.013	1.3MetArg: 1.3 ± 0.014	1.906MetSer: 1.906 ± 0.019	1.368MetThr: 1.368 ± 0.016	1.346MetVal: 1.346 ± 0.018	0.274MetTrp: 0.274 ± 0.007	0.522MetTyr: 0.522 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.179AsnAla: 3.179 ± 0.024	0.452AsnCys: 0.452 ± 0.008	1.986AsnAsp: 1.986 ± 0.02	1.945AsnGlu: 1.945 ± 0.019	1.445AsnPhe: 1.445 ± 0.015	3.15AsnGly: 3.15 ± 0.029	0.834AsnHis: 0.834 ± 0.012	2.002AsnIle: 2.002 ± 0.018	1.569AsnLys: 1.569 ± 0.018	3.225AsnLeu: 3.225 ± 0.024	0.863AsnMet: 0.863 ± 0.011	1.588AsnAsn: 1.588 ± 0.022	2.447AsnPro: 2.447 ± 0.021	1.308AsnGln: 1.308 ± 0.018	1.84AsnArg: 1.84 ± 0.016	2.669AsnSer: 2.669 ± 0.021	2.257AsnThr: 2.257 ± 0.018	2.328AsnVal: 2.328 ± 0.021	0.573AsnTrp: 0.573 ± 0.01	1.063AsnTyr: 1.063 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.713ProAla: 5.713 ± 0.055	0.529ProCys: 0.529 ± 0.01	3.188ProAsp: 3.188 ± 0.021	3.883ProGlu: 3.883 ± 0.038	2.07ProPhe: 2.07 ± 0.019	4.109ProGly: 4.109 ± 0.036	1.284ProHis: 1.284 ± 0.015	2.531ProIle: 2.531 ± 0.02	2.727ProLys: 2.727 ± 0.027	4.646ProLeu: 4.646 ± 0.031	1.16ProMet: 1.16 ± 0.015	2.211ProAsn: 2.211 ± 0.022	5.368ProPro: 5.368 ± 0.07	2.438ProGln: 2.438 ± 0.027	3.474ProArg: 3.474 ± 0.027	5.821ProSer: 5.821 ± 0.044	4.139ProThr: 4.139 ± 0.04	3.678ProVal: 3.678 ± 0.03	0.803ProTrp: 0.803 ± 0.011	1.492ProTyr: 1.492 ± 0.017	0.003ProXaa: 0.003 ± 0.001
Gln	3.465GlnAla: 3.465 ± 0.027	0.438GlnCys: 0.438 ± 0.011	1.991GlnAsp: 1.991 ± 0.02	2.225GlnGlu: 2.225 ± 0.018	1.226GlnPhe: 1.226 ± 0.015	2.409GlnGly: 2.409 ± 0.018	1.06GlnHis: 1.06 ± 0.017	1.774GlnIle: 1.774 ± 0.017	1.875GlnLys: 1.875 ± 0.018	3.278GlnLeu: 3.278 ± 0.026	0.891GlnMet: 0.891 ± 0.013	1.466GlnAsn: 1.466 ± 0.015	2.538GlnPro: 2.538 ± 0.029	2.514GlnGln: 2.514 ± 0.042	2.536GlnArg: 2.536 ± 0.026	2.939GlnSer: 2.939 ± 0.024	2.335GlnThr: 2.335 ± 0.028	2.15GlnVal: 2.15 ± 0.02	0.568GlnTrp: 0.568 ± 0.009	1.091GlnTyr: 1.091 ± 0.014	0.001GlnXaa: 0.001 ± 0.0
Arg	4.585ArgAla: 4.585 ± 0.031	0.685ArgCys: 0.685 ± 0.011	3.366ArgAsp: 3.366 ± 0.028	3.619ArgGlu: 3.619 ± 0.032	2.083ArgPhe: 2.083 ± 0.02	3.782ArgGly: 3.782 ± 0.031	1.534ArgHis: 1.534 ± 0.017	2.729ArgIle: 2.729 ± 0.021	3.287ArgLys: 3.287 ± 0.025	5.203ArgLeu: 5.203 ± 0.033	1.286ArgMet: 1.286 ± 0.014	2.18ArgAsn: 2.18 ± 0.019	3.578ArgPro: 3.578 ± 0.029	2.537ArgGln: 2.537 ± 0.021	4.985ArgArg: 4.985 ± 0.038	4.565ArgSer: 4.565 ± 0.039	3.209ArgThr: 3.209 ± 0.023	3.307ArgVal: 3.307 ± 0.029	0.939ArgTrp: 0.939 ± 0.013	1.58ArgTyr: 1.58 ± 0.015	0.001ArgXaa: 0.001 ± 0.0
Ser	6.832SerAla: 6.832 ± 0.039	0.877SerCys: 0.877 ± 0.014	4.155SerAsp: 4.155 ± 0.027	3.959SerGlu: 3.959 ± 0.026	3.023SerPhe: 3.023 ± 0.022	5.698SerGly: 5.698 ± 0.039	1.867SerHis: 1.867 ± 0.02	3.814SerIle: 3.814 ± 0.027	3.646SerLys: 3.646 ± 0.031	6.905SerLeu: 6.905 ± 0.037	1.754SerMet: 1.754 ± 0.016	2.923SerAsn: 2.923 ± 0.021	5.405SerPro: 5.405 ± 0.045	3.139SerGln: 3.139 ± 0.025	4.866SerArg: 4.866 ± 0.04	8.564SerSer: 8.564 ± 0.063	5.546SerThr: 5.546 ± 0.044	4.604SerVal: 4.604 ± 0.031	1.148SerTrp: 1.148 ± 0.013	2.057SerTyr: 2.057 ± 0.02	0.002SerXaa: 0.002 ± 0.001
Thr	5.626ThrAla: 5.626 ± 0.036	0.753ThrCys: 0.753 ± 0.013	2.935ThrAsp: 2.935 ± 0.024	3.19ThrGlu: 3.19 ± 0.025	2.34ThrPhe: 2.34 ± 0.025	4.337ThrGly: 4.337 ± 0.043	1.23ThrHis: 1.23 ± 0.015	3.121ThrIle: 3.121 ± 0.032	2.718ThrLys: 2.718 ± 0.022	5.193ThrLeu: 5.193 ± 0.046	1.232ThrMet: 1.232 ± 0.015	2.235ThrAsn: 2.235 ± 0.021	4.457ThrPro: 4.457 ± 0.036	2.115ThrGln: 2.115 ± 0.02	3.074ThrArg: 3.074 ± 0.024	5.436ThrSer: 5.436 ± 0.046	4.722ThrThr: 4.722 ± 0.056	3.871ThrVal: 3.871 ± 0.043	0.937ThrTrp: 0.937 ± 0.013	1.683ThrTyr: 1.683 ± 0.02	0.001ThrXaa: 0.001 ± 0.001
Val	5.713ValAla: 5.713 ± 0.035	0.835ValCys: 0.835 ± 0.013	3.793ValAsp: 3.793 ± 0.025	3.904ValGlu: 3.904 ± 0.028	2.598ValPhe: 2.598 ± 0.023	4.185ValGly: 4.185 ± 0.032	1.352ValHis: 1.352 ± 0.013	2.982ValIle: 2.982 ± 0.024	2.937ValLys: 2.937 ± 0.023	5.567ValLeu: 5.567 ± 0.041	1.328ValMet: 1.328 ± 0.015	2.259ValAsn: 2.259 ± 0.018	3.737ValPro: 3.737 ± 0.031	2.288ValGln: 2.288 ± 0.019	3.389ValArg: 3.389 ± 0.023	4.696ValSer: 4.696 ± 0.029	3.776ValThr: 3.776 ± 0.036	4.544ValVal: 4.544 ± 0.035	0.926ValTrp: 0.926 ± 0.014	1.735ValTyr: 1.735 ± 0.018	0.001ValXaa: 0.001 ± 0.0
Trp	1.231TrpAla: 1.231 ± 0.012	0.2TrpCys: 0.2 ± 0.006	0.946TrpAsp: 0.946 ± 0.013	0.851TrpGlu: 0.851 ± 0.011	0.574TrpPhe: 0.574 ± 0.01	0.998TrpGly: 0.998 ± 0.014	0.376TrpHis: 0.376 ± 0.008	0.767TrpIle: 0.767 ± 0.012	0.803TrpLys: 0.803 ± 0.013	1.378TrpLeu: 1.378 ± 0.017	0.389TrpMet: 0.389 ± 0.008	0.671TrpAsn: 0.671 ± 0.01	0.666TrpPro: 0.666 ± 0.01	0.593TrpGln: 0.593 ± 0.009	0.949TrpArg: 0.949 ± 0.012	1.083TrpSer: 1.083 ± 0.013	0.99TrpThr: 0.99 ± 0.013	0.921TrpVal: 0.921 ± 0.013	0.299TrpTrp: 0.299 ± 0.007	0.461TrpTyr: 0.461 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.178TyrAla: 2.178 ± 0.02	0.418TyrCys: 0.418 ± 0.009	1.688TyrAsp: 1.688 ± 0.017	1.497TyrGlu: 1.497 ± 0.015	1.197TyrPhe: 1.197 ± 0.013	2.142TyrGly: 2.142 ± 0.022	0.735TyrHis: 0.735 ± 0.01	1.299TyrIle: 1.299 ± 0.016	1.098TyrLys: 1.098 ± 0.014	2.549TyrLeu: 2.549 ± 0.022	0.621TyrMet: 0.621 ± 0.01	1.115TyrAsn: 1.115 ± 0.014	1.441TyrPro: 1.441 ± 0.016	1.034TyrGln: 1.034 ± 0.014	1.546TyrArg: 1.546 ± 0.015	1.961TyrSer: 1.961 ± 0.019	1.591TyrThr: 1.591 ± 0.019	1.653TyrVal: 1.653 ± 0.019	0.466TyrTrp: 0.466 ± 0.009	0.902TyrTyr: 0.902 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.002XaaPro: 0.002 ± 0.001	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.001	0.002XaaSer: 0.002 ± 0.001	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.124XaaXaa: 0.124 ± 0.018

Statistics based on 13783 proteins (6540505 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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