Amino acid dipepetide frequency for Prunus avium (Cherry) (Cerasus avium)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.038AlaAla: 6.038 ± 0.031	1.274AlaCys: 1.274 ± 0.012	3.123AlaAsp: 3.123 ± 0.016	4.18AlaGlu: 4.18 ± 0.024	2.814AlaPhe: 2.814 ± 0.016	4.008AlaGly: 4.008 ± 0.02	1.381AlaHis: 1.381 ± 0.011	3.708AlaIle: 3.708 ± 0.019	3.892AlaLys: 3.892 ± 0.02	6.769AlaLeu: 6.769 ± 0.023	1.731AlaMet: 1.731 ± 0.011	2.649AlaAsn: 2.649 ± 0.014	2.789AlaPro: 2.789 ± 0.018	2.22AlaGln: 2.22 ± 0.014	3.244AlaArg: 3.244 ± 0.015	5.988AlaSer: 5.988 ± 0.025	3.545AlaThr: 3.545 ± 0.018	4.647AlaVal: 4.647 ± 0.021	0.786AlaTrp: 0.786 ± 0.008	1.861AlaTyr: 1.861 ± 0.013	0.002AlaXaa: 0.002 ± 0.0
Cys	1.007CysAla: 1.007 ± 0.01	0.517CysCys: 0.517 ± 0.006	0.871CysAsp: 0.871 ± 0.008	0.905CysGlu: 0.905 ± 0.009	0.913CysPhe: 0.913 ± 0.008	1.402CysGly: 1.402 ± 0.012	0.486CysHis: 0.486 ± 0.005	1.029CysIle: 1.029 ± 0.009	1.21CysLys: 1.21 ± 0.013	1.938CysLeu: 1.938 ± 0.013	0.464CysMet: 0.464 ± 0.006	0.884CysAsn: 0.884 ± 0.009	0.95CysPro: 0.95 ± 0.01	0.635CysGln: 0.635 ± 0.007	1.031CysArg: 1.031 ± 0.009	1.847CysSer: 1.847 ± 0.012	0.923CysThr: 0.923 ± 0.009	1.049CysVal: 1.049 ± 0.009	0.244CysTrp: 0.244 ± 0.004	0.528CysTyr: 0.528 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	3.459AspAla: 3.459 ± 0.018	0.994AspCys: 0.994 ± 0.01	3.59AspAsp: 3.59 ± 0.022	3.969AspGlu: 3.969 ± 0.023	2.404AspPhe: 2.404 ± 0.015	3.767AspGly: 3.767 ± 0.018	1.317AspHis: 1.317 ± 0.011	3.0AspIle: 3.0 ± 0.014	2.701AspLys: 2.701 ± 0.014	5.218AspLeu: 5.218 ± 0.022	1.333AspMet: 1.333 ± 0.011	2.059AspAsn: 2.059 ± 0.013	2.584AspPro: 2.584 ± 0.014	1.906AspGln: 1.906 ± 0.012	2.369AspArg: 2.369 ± 0.016	4.163AspSer: 4.163 ± 0.02	2.223AspThr: 2.223 ± 0.014	3.679AspVal: 3.679 ± 0.017	0.73AspTrp: 0.73 ± 0.007	1.559AspTyr: 1.559 ± 0.011	0.0AspXaa: 0.0 ± 0.0
Glu	4.874GluAla: 4.874 ± 0.021	0.938GluCys: 0.938 ± 0.009	3.972GluAsp: 3.972 ± 0.022	6.008GluGlu: 6.008 ± 0.037	2.417GluPhe: 2.417 ± 0.012	3.851GluGly: 3.851 ± 0.02	1.306GluHis: 1.306 ± 0.011	3.753GluIle: 3.753 ± 0.016	4.741GluLys: 4.741 ± 0.028	6.093GluLeu: 6.093 ± 0.026	1.747GluMet: 1.747 ± 0.013	3.091GluAsn: 3.091 ± 0.018	2.177GluPro: 2.177 ± 0.016	2.216GluGln: 2.216 ± 0.015	3.357GluArg: 3.357 ± 0.023	4.488GluSer: 4.488 ± 0.022	3.058GluThr: 3.058 ± 0.017	4.205GluVal: 4.205 ± 0.019	0.773GluTrp: 0.773 ± 0.008	1.673GluTyr: 1.673 ± 0.011	0.001GluXaa: 0.001 ± 0.0
Phe	2.432PheAla: 2.432 ± 0.016	0.898PheCys: 0.898 ± 0.008	2.368PheAsp: 2.368 ± 0.013	2.341PheGlu: 2.341 ± 0.015	1.926PhePhe: 1.926 ± 0.014	3.092PheGly: 3.092 ± 0.021	1.106PheHis: 1.106 ± 0.009	2.06PheIle: 2.06 ± 0.012	2.171PheLys: 2.171 ± 0.012	4.285PheLeu: 4.285 ± 0.022	0.953PheMet: 0.953 ± 0.009	1.818PheAsn: 1.818 ± 0.011	2.119PhePro: 2.119 ± 0.014	1.624PheGln: 1.624 ± 0.011	2.018PheArg: 2.018 ± 0.012	4.155PheSer: 4.155 ± 0.02	2.011PheThr: 2.011 ± 0.013	2.762PheVal: 2.762 ± 0.017	0.585PheTrp: 0.585 ± 0.007	1.282PheTyr: 1.282 ± 0.01	0.001PheXaa: 0.001 ± 0.0
Gly	3.817GlyAla: 3.817 ± 0.023	1.351GlyCys: 1.351 ± 0.012	3.35GlyAsp: 3.35 ± 0.017	3.588GlyGlu: 3.588 ± 0.018	3.219GlyPhe: 3.219 ± 0.018	5.178GlyGly: 5.178 ± 0.048	1.582GlyHis: 1.582 ± 0.013	3.68GlyIle: 3.68 ± 0.021	4.074GlyLys: 4.074 ± 0.019	6.109GlyLeu: 6.109 ± 0.024	1.508GlyMet: 1.508 ± 0.012	3.223GlyAsn: 3.223 ± 0.021	2.46GlyPro: 2.46 ± 0.016	2.167GlyGln: 2.167 ± 0.013	3.516GlyArg: 3.516 ± 0.019	6.081GlySer: 6.081 ± 0.026	3.269GlyThr: 3.269 ± 0.015	4.154GlyVal: 4.154 ± 0.02	0.879GlyTrp: 0.879 ± 0.008	2.056GlyTyr: 2.056 ± 0.015	0.002GlyXaa: 0.002 ± 0.0
His	1.46HisAla: 1.46 ± 0.01	0.53HisCys: 0.53 ± 0.006	1.232HisAsp: 1.232 ± 0.011	1.396HisGlu: 1.396 ± 0.011	1.085HisPhe: 1.085 ± 0.008	1.761HisGly: 1.761 ± 0.015	1.001HisHis: 1.001 ± 0.011	1.262HisIle: 1.262 ± 0.01	1.241HisLys: 1.241 ± 0.01	2.563HisLeu: 2.563 ± 0.014	0.564HisMet: 0.564 ± 0.006	1.049HisAsn: 1.049 ± 0.009	1.392HisPro: 1.392 ± 0.012	1.075HisGln: 1.075 ± 0.01	1.333HisArg: 1.333 ± 0.011	1.954HisSer: 1.954 ± 0.014	0.996HisThr: 0.996 ± 0.009	1.58HisVal: 1.58 ± 0.011	0.317HisTrp: 0.317 ± 0.005	0.703HisTyr: 0.703 ± 0.007	0.001HisXaa: 0.001 ± 0.0
Ile	3.505IleAla: 3.505 ± 0.015	1.084IleCys: 1.084 ± 0.009	2.824IleAsp: 2.824 ± 0.015	3.227IleGlu: 3.227 ± 0.017	2.254IlePhe: 2.254 ± 0.017	3.428IleGly: 3.428 ± 0.015	1.29IleHis: 1.29 ± 0.009	2.729IleIle: 2.729 ± 0.014	2.903IleLys: 2.903 ± 0.014	5.182IleLeu: 5.182 ± 0.023	1.099IleMet: 1.099 ± 0.009	2.196IleAsn: 2.196 ± 0.012	3.076IlePro: 3.076 ± 0.023	1.99IleGln: 1.99 ± 0.013	2.59IleArg: 2.59 ± 0.014	4.914IleSer: 4.914 ± 0.022	2.56IleThr: 2.56 ± 0.014	3.395IleVal: 3.395 ± 0.016	0.715IleTrp: 0.715 ± 0.008	1.502IleTyr: 1.502 ± 0.012	0.001IleXaa: 0.001 ± 0.0
Lys	4.077LysAla: 4.077 ± 0.018	1.004LysCys: 1.004 ± 0.009	3.294LysAsp: 3.294 ± 0.017	4.662LysGlu: 4.662 ± 0.026	2.225LysPhe: 2.225 ± 0.012	3.668LysGly: 3.668 ± 0.015	1.386LysHis: 1.386 ± 0.011	3.198LysIle: 3.198 ± 0.015	4.625LysLys: 4.625 ± 0.029	6.19LysLeu: 6.19 ± 0.023	1.482LysMet: 1.482 ± 0.011	2.729LysAsn: 2.729 ± 0.015	2.763LysPro: 2.763 ± 0.018	2.335LysGln: 2.335 ± 0.014	3.609LysArg: 3.609 ± 0.019	4.631LysSer: 4.631 ± 0.023	2.88LysThr: 2.88 ± 0.016	3.875LysVal: 3.875 ± 0.018	0.804LysTrp: 0.804 ± 0.007	1.648LysTyr: 1.648 ± 0.013	0.001LysXaa: 0.001 ± 0.0
Leu	6.498LeuAla: 6.498 ± 0.024	1.909LeuCys: 1.909 ± 0.014	5.325LeuAsp: 5.325 ± 0.023	6.575LeuGlu: 6.575 ± 0.029	3.789LeuPhe: 3.789 ± 0.021	5.951LeuGly: 5.951 ± 0.023	2.66LeuHis: 2.66 ± 0.016	4.616LeuIle: 4.616 ± 0.02	6.378LeuLys: 6.378 ± 0.024	9.921LeuLeu: 9.921 ± 0.04	2.099LeuMet: 2.099 ± 0.013	4.07LeuAsn: 4.07 ± 0.02	5.366LeuPro: 5.366 ± 0.026	4.517LeuGln: 4.517 ± 0.025	5.442LeuArg: 5.442 ± 0.022	8.952LeuSer: 8.952 ± 0.037	4.617LeuThr: 4.617 ± 0.022	6.511LeuVal: 6.511 ± 0.023	1.176LeuTrp: 1.176 ± 0.011	2.548LeuTyr: 2.548 ± 0.014	0.002LeuXaa: 0.002 ± 0.0
Met	2.069MetAla: 2.069 ± 0.013	0.331MetCys: 0.331 ± 0.004	1.397MetAsp: 1.397 ± 0.011	1.919MetGlu: 1.919 ± 0.013	0.788MetPhe: 0.788 ± 0.008	1.611MetGly: 1.611 ± 0.011	0.569MetHis: 0.569 ± 0.006	1.139MetIle: 1.139 ± 0.01	1.6MetLys: 1.6 ± 0.011	2.177MetLeu: 2.177 ± 0.012	0.644MetMet: 0.644 ± 0.007	1.001MetAsn: 1.001 ± 0.008	1.09MetPro: 1.09 ± 0.009	0.929MetGln: 0.929 ± 0.009	1.188MetArg: 1.188 ± 0.01	1.738MetSer: 1.738 ± 0.012	1.0MetThr: 1.0 ± 0.008	1.633MetVal: 1.633 ± 0.01	0.264MetTrp: 0.264 ± 0.004	0.577MetTyr: 0.577 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.704AsnAla: 2.704 ± 0.015	0.915AsnCys: 0.915 ± 0.009	2.098AsnAsp: 2.098 ± 0.011	2.563AsnGlu: 2.563 ± 0.017	2.008AsnPhe: 2.008 ± 0.013	3.294AsnGly: 3.294 ± 0.02	1.143AsnHis: 1.143 ± 0.009	2.491AsnIle: 2.491 ± 0.015	2.477AsnLys: 2.477 ± 0.015	5.025AsnLeu: 5.025 ± 0.028	1.112AsnMet: 1.112 ± 0.01	2.438AsnAsn: 2.438 ± 0.023	2.414AsnPro: 2.414 ± 0.015	1.807AsnGln: 1.807 ± 0.011	1.978AsnArg: 1.978 ± 0.015	4.045AsnSer: 4.045 ± 0.019	1.989AsnThr: 1.989 ± 0.014	2.829AsnVal: 2.829 ± 0.015	0.594AsnTrp: 0.594 ± 0.007	1.344AsnTyr: 1.344 ± 0.01	0.001AsnXaa: 0.001 ± 0.0
Pro	2.979ProAla: 2.979 ± 0.019	0.789ProCys: 0.789 ± 0.008	2.502ProAsp: 2.502 ± 0.017	3.175ProGlu: 3.175 ± 0.018	1.943ProPhe: 1.943 ± 0.013	2.631ProGly: 2.631 ± 0.017	1.178ProHis: 1.178 ± 0.011	2.39ProIle: 2.39 ± 0.015	2.867ProLys: 2.867 ± 0.016	4.297ProLeu: 4.297 ± 0.018	0.937ProMet: 0.937 ± 0.009	2.513ProAsn: 2.513 ± 0.015	3.851ProPro: 3.851 ± 0.056	1.939ProGln: 1.939 ± 0.016	2.275ProArg: 2.275 ± 0.015	5.249ProSer: 5.249 ± 0.026	2.687ProThr: 2.687 ± 0.017	3.03ProVal: 3.03 ± 0.02	0.59ProTrp: 0.59 ± 0.007	1.326ProTyr: 1.326 ± 0.01	0.001ProXaa: 0.001 ± 0.0
Gln	2.494GlnAla: 2.494 ± 0.015	0.606GlnCys: 0.606 ± 0.007	1.733GlnAsp: 1.733 ± 0.011	2.479GlnGlu: 2.479 ± 0.015	1.448GlnPhe: 1.448 ± 0.01	2.212GlnGly: 2.212 ± 0.014	0.978GlnHis: 0.978 ± 0.011	2.03GlnIle: 2.03 ± 0.013	2.375GlnLys: 2.375 ± 0.013	3.87GlnLeu: 3.87 ± 0.021	0.991GlnMet: 0.991 ± 0.009	1.878GlnAsn: 1.878 ± 0.013	1.843GlnPro: 1.843 ± 0.015	2.158GlnGln: 2.158 ± 0.033	2.114GlnArg: 2.114 ± 0.013	2.997GlnSer: 2.997 ± 0.017	1.843GlnThr: 1.843 ± 0.013	2.475GlnVal: 2.475 ± 0.014	0.476GlnTrp: 0.476 ± 0.006	0.956GlnTyr: 0.956 ± 0.008	0.001GlnXaa: 0.001 ± 0.0
Arg	3.163ArgAla: 3.163 ± 0.018	0.964ArgCys: 0.964 ± 0.01	2.63ArgAsp: 2.63 ± 0.016	3.265ArgGlu: 3.265 ± 0.02	2.184ArgPhe: 2.184 ± 0.012	3.146ArgGly: 3.146 ± 0.019	1.273ArgHis: 1.273 ± 0.009	2.77ArgIle: 2.77 ± 0.015	3.714ArgLys: 3.714 ± 0.018	5.029ArgLeu: 5.029 ± 0.019	1.28ArgMet: 1.28 ± 0.01	2.456ArgAsn: 2.456 ± 0.014	2.275ArgPro: 2.275 ± 0.013	1.826ArgGln: 1.826 ± 0.011	3.671ArgArg: 3.671 ± 0.019	4.205ArgSer: 4.205 ± 0.023	2.405ArgThr: 2.405 ± 0.014	3.271ArgVal: 3.271 ± 0.017	0.734ArgTrp: 0.734 ± 0.008	1.438ArgTyr: 1.438 ± 0.011	0.002ArgXaa: 0.002 ± 0.0
Ser	5.38SerAla: 5.38 ± 0.022	1.746SerCys: 1.746 ± 0.013	4.446SerAsp: 4.446 ± 0.02	4.841SerGlu: 4.841 ± 0.024	3.952SerPhe: 3.952 ± 0.018	5.948SerGly: 5.948 ± 0.029	2.124SerHis: 2.124 ± 0.013	4.506SerIle: 4.506 ± 0.021	5.008SerLys: 5.008 ± 0.023	8.965SerLeu: 8.965 ± 0.035	2.074SerMet: 2.074 ± 0.011	4.24SerAsn: 4.24 ± 0.021	4.445SerPro: 4.445 ± 0.027	3.146SerGln: 3.146 ± 0.019	4.359SerArg: 4.359 ± 0.022	11.07SerSer: 11.07 ± 0.045	4.779SerThr: 4.779 ± 0.021	5.228SerVal: 5.228 ± 0.021	1.194SerTrp: 1.194 ± 0.011	2.336SerTyr: 2.336 ± 0.015	0.003SerXaa: 0.003 ± 0.0
Thr	3.339ThrAla: 3.339 ± 0.017	0.93ThrCys: 0.93 ± 0.008	2.284ThrAsp: 2.284 ± 0.017	2.837ThrGlu: 2.837 ± 0.016	2.065ThrPhe: 2.065 ± 0.013	3.231ThrGly: 3.231 ± 0.019	1.101ThrHis: 1.101 ± 0.01	2.685ThrIle: 2.685 ± 0.014	2.741ThrLys: 2.741 ± 0.016	4.794ThrLeu: 4.794 ± 0.02	1.118ThrMet: 1.118 ± 0.009	2.204ThrAsn: 2.204 ± 0.015	2.555ThrPro: 2.555 ± 0.019	1.675ThrGln: 1.675 ± 0.011	2.325ThrArg: 2.325 ± 0.012	4.658ThrSer: 4.658 ± 0.02	3.04ThrThr: 3.04 ± 0.02	3.238ThrVal: 3.238 ± 0.015	0.669ThrTrp: 0.669 ± 0.008	1.42ThrTyr: 1.42 ± 0.011	0.001ThrXaa: 0.001 ± 0.0
Val	4.734ValAla: 4.734 ± 0.024	1.171ValCys: 1.171 ± 0.011	3.745ValAsp: 3.745 ± 0.017	4.423ValGlu: 4.423 ± 0.023	2.721ValPhe: 2.721 ± 0.016	4.217ValGly: 4.217 ± 0.021	1.569ValHis: 1.569 ± 0.012	3.309ValIle: 3.309 ± 0.017	3.855ValLys: 3.855 ± 0.017	6.406ValLeu: 6.406 ± 0.028	1.45ValMet: 1.45 ± 0.01	2.646ValAsn: 2.646 ± 0.014	3.249ValPro: 3.249 ± 0.018	2.386ValGln: 2.386 ± 0.014	3.061ValArg: 3.061 ± 0.017	5.42ValSer: 5.42 ± 0.022	3.124ValThr: 3.124 ± 0.015	4.886ValVal: 4.886 ± 0.022	0.771ValTrp: 0.771 ± 0.008	1.937ValTyr: 1.937 ± 0.013	0.001ValXaa: 0.001 ± 0.0
Trp	0.775TrpAla: 0.775 ± 0.009	0.242TrpCys: 0.242 ± 0.005	0.718TrpAsp: 0.718 ± 0.008	0.767TrpGlu: 0.767 ± 0.008	0.576TrpPhe: 0.576 ± 0.006	0.745TrpGly: 0.745 ± 0.008	0.316TrpHis: 0.316 ± 0.006	0.661TrpIle: 0.661 ± 0.006	0.972TrpLys: 0.972 ± 0.009	1.257TrpLeu: 1.257 ± 0.01	0.341TrpMet: 0.341 ± 0.005	0.731TrpAsn: 0.731 ± 0.007	0.5TrpPro: 0.5 ± 0.005	0.454TrpGln: 0.454 ± 0.006	0.805TrpArg: 0.805 ± 0.008	0.972TrpSer: 0.972 ± 0.008	0.664TrpThr: 0.664 ± 0.008	0.871TrpVal: 0.871 ± 0.008	0.241TrpTrp: 0.241 ± 0.004	0.335TrpTyr: 0.335 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.845TyrAla: 1.845 ± 0.013	0.641TyrCys: 0.641 ± 0.006	1.522TyrAsp: 1.522 ± 0.01	1.617TyrGlu: 1.617 ± 0.011	1.278TyrPhe: 1.278 ± 0.01	2.123TyrGly: 2.123 ± 0.014	0.732TyrHis: 0.732 ± 0.009	1.449TyrIle: 1.449 ± 0.012	1.539TyrLys: 1.539 ± 0.011	2.831TyrLeu: 2.831 ± 0.018	0.736TyrMet: 0.736 ± 0.007	1.393TyrAsn: 1.393 ± 0.013	1.248TyrPro: 1.248 ± 0.011	0.947TyrGln: 0.947 ± 0.008	1.413TyrArg: 1.413 ± 0.01	2.257TyrSer: 2.257 ± 0.014	1.296TyrThr: 1.296 ± 0.01	1.761TyrVal: 1.761 ± 0.012	0.401TyrTrp: 0.401 ± 0.006	0.953TyrTyr: 0.953 ± 0.009	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.002XaaLys: 0.002 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.003XaaSer: 0.003 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.002XaaVal: 0.002 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.04XaaXaa: 0.04 ± 0.007

Statistics based on 30515 proteins (14032431 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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