Amino acid dipepetide frequency for Naasia lichenicola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.522AlaAla: 19.522 ± 0.201	0.608AlaCys: 0.608 ± 0.024	8.323AlaAsp: 8.323 ± 0.09	7.499AlaGlu: 7.499 ± 0.096	3.92AlaPhe: 3.92 ± 0.056	11.583AlaGly: 11.583 ± 0.119	2.252AlaHis: 2.252 ± 0.049	6.776AlaIle: 6.776 ± 0.092	2.695AlaLys: 2.695 ± 0.063	13.581AlaLeu: 13.581 ± 0.14	2.642AlaMet: 2.642 ± 0.047	2.333AlaAsn: 2.333 ± 0.052	6.304AlaPro: 6.304 ± 0.105	3.705AlaGln: 3.705 ± 0.062	8.487AlaArg: 8.487 ± 0.116	8.161AlaSer: 8.161 ± 0.096	7.315AlaThr: 7.315 ± 0.102	11.085AlaVal: 11.085 ± 0.118	1.696AlaTrp: 1.696 ± 0.04	2.36AlaTyr: 2.36 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	0.557CysAla: 0.557 ± 0.026	0.046CysCys: 0.046 ± 0.007	0.299CysAsp: 0.299 ± 0.017	0.217CysGlu: 0.217 ± 0.015	0.163CysPhe: 0.163 ± 0.012	0.497CysGly: 0.497 ± 0.019	0.108CysHis: 0.108 ± 0.011	0.212CysIle: 0.212 ± 0.014	0.055CysLys: 0.055 ± 0.006	0.392CysLeu: 0.392 ± 0.021	0.078CysMet: 0.078 ± 0.009	0.106CysAsn: 0.106 ± 0.009	0.243CysPro: 0.243 ± 0.017	0.095CysGln: 0.095 ± 0.009	0.284CysArg: 0.284 ± 0.018	0.361CysSer: 0.361 ± 0.019	0.265CysThr: 0.265 ± 0.019	0.371CysVal: 0.371 ± 0.02	0.062CysTrp: 0.062 ± 0.007	0.096CysTyr: 0.096 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	8.239AspAla: 8.239 ± 0.101	0.233AspCys: 0.233 ± 0.014	4.262AspAsp: 4.262 ± 0.074	4.336AspGlu: 4.336 ± 0.073	1.916AspPhe: 1.916 ± 0.044	6.233AspGly: 6.233 ± 0.091	1.196AspHis: 1.196 ± 0.035	2.544AspIle: 2.544 ± 0.054	0.896AspLys: 0.896 ± 0.034	6.359AspLeu: 6.359 ± 0.074	0.788AspMet: 0.788 ± 0.027	0.986AspAsn: 0.986 ± 0.032	4.216AspPro: 4.216 ± 0.066	1.699AspGln: 1.699 ± 0.041	4.723AspArg: 4.723 ± 0.078	3.456AspSer: 3.456 ± 0.063	2.775AspThr: 2.775 ± 0.051	5.235AspVal: 5.235 ± 0.069	0.978AspTrp: 0.978 ± 0.029	1.387AspTyr: 1.387 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	6.407GluAla: 6.407 ± 0.085	0.184GluCys: 0.184 ± 0.012	2.69GluAsp: 2.69 ± 0.055	2.736GluGlu: 2.736 ± 0.058	1.729GluPhe: 1.729 ± 0.043	3.755GluGly: 3.755 ± 0.063	1.466GluHis: 1.466 ± 0.083	2.759GluIle: 2.759 ± 0.052	1.334GluLys: 1.334 ± 0.039	6.99GluLeu: 6.99 ± 0.093	0.879GluMet: 0.879 ± 0.027	1.161GluAsn: 1.161 ± 0.039	2.876GluPro: 2.876 ± 0.056	2.151GluGln: 2.151 ± 0.048	4.863GluArg: 4.863 ± 0.082	3.365GluSer: 3.365 ± 0.06	2.932GluThr: 2.932 ± 0.055	4.481GluVal: 4.481 ± 0.07	0.808GluTrp: 0.808 ± 0.031	1.045GluTyr: 1.045 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	4.295PheAla: 4.295 ± 0.063	0.182PheCys: 0.182 ± 0.011	2.431PheAsp: 2.431 ± 0.052	1.838PheGlu: 1.838 ± 0.046	1.04PhePhe: 1.04 ± 0.04	3.649PheGly: 3.649 ± 0.063	0.532PheHis: 0.532 ± 0.021	1.301PheIle: 1.301 ± 0.036	0.491PheLys: 0.491 ± 0.023	2.939PheLeu: 2.939 ± 0.057	0.421PheMet: 0.421 ± 0.02	0.676PheAsn: 0.676 ± 0.026	1.477PhePro: 1.477 ± 0.038	0.782PheGln: 0.782 ± 0.029	1.816PheArg: 1.816 ± 0.043	2.009PheSer: 2.009 ± 0.042	2.014PheThr: 2.014 ± 0.047	2.722PheVal: 2.722 ± 0.048	0.49PheTrp: 0.49 ± 0.021	0.667PheTyr: 0.667 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	10.523GlyAla: 10.523 ± 0.103	0.489GlyCys: 0.489 ± 0.022	4.935GlyAsp: 4.935 ± 0.063	4.709GlyGlu: 4.709 ± 0.067	3.326GlyPhe: 3.326 ± 0.058	7.794GlyGly: 7.794 ± 0.111	1.727GlyHis: 1.727 ± 0.043	5.172GlyIle: 5.172 ± 0.069	2.052GlyLys: 2.052 ± 0.051	8.913GlyLeu: 8.913 ± 0.1	1.863GlyMet: 1.863 ± 0.034	1.815GlyAsn: 1.815 ± 0.046	4.016GlyPro: 4.016 ± 0.061	2.502GlyGln: 2.502 ± 0.053	6.371GlyArg: 6.371 ± 0.085	6.55GlySer: 6.55 ± 0.1	5.603GlyThr: 5.603 ± 0.089	7.615GlyVal: 7.615 ± 0.087	1.622GlyTrp: 1.622 ± 0.039	2.364GlyTyr: 2.364 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.146HisAla: 2.146 ± 0.039	0.104HisCys: 0.104 ± 0.011	1.214HisAsp: 1.214 ± 0.041	1.139HisGlu: 1.139 ± 0.079	0.586HisPhe: 0.586 ± 0.024	1.932HisGly: 1.932 ± 0.038	0.482HisHis: 0.482 ± 0.021	0.761HisIle: 0.761 ± 0.022	0.241HisLys: 0.241 ± 0.015	2.004HisLeu: 2.004 ± 0.05	0.311HisMet: 0.311 ± 0.016	0.337HisAsn: 0.337 ± 0.021	1.421HisPro: 1.421 ± 0.04	0.496HisGln: 0.496 ± 0.022	1.555HisArg: 1.555 ± 0.041	1.14HisSer: 1.14 ± 0.033	0.903HisThr: 0.903 ± 0.029	1.389HisVal: 1.389 ± 0.033	0.279HisTrp: 0.279 ± 0.018	0.449HisTyr: 0.449 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	7.752IleAla: 7.752 ± 0.09	0.266IleCys: 0.266 ± 0.015	3.731IleAsp: 3.731 ± 0.057	3.128IleGlu: 3.128 ± 0.055	1.268IlePhe: 1.268 ± 0.036	5.241IleGly: 5.241 ± 0.077	0.783IleHis: 0.783 ± 0.027	1.98IleIle: 1.98 ± 0.048	0.886IleLys: 0.886 ± 0.032	4.069IleLeu: 4.069 ± 0.064	0.614IleMet: 0.614 ± 0.025	0.951IleAsn: 0.951 ± 0.033	2.625IlePro: 2.625 ± 0.045	1.131IleGln: 1.131 ± 0.03	3.062IleArg: 3.062 ± 0.057	2.938IleSer: 2.938 ± 0.052	2.978IleThr: 2.978 ± 0.056	4.924IleVal: 4.924 ± 0.073	0.569IleTrp: 0.569 ± 0.023	0.83IleTyr: 0.83 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	2.526LysAla: 2.526 ± 0.057	0.063LysCys: 0.063 ± 0.008	1.082LysAsp: 1.082 ± 0.034	0.925LysGlu: 0.925 ± 0.033	0.532LysPhe: 0.532 ± 0.024	1.518LysGly: 1.518 ± 0.045	0.434LysHis: 0.434 ± 0.017	0.885LysIle: 0.885 ± 0.029	0.705LysLys: 0.705 ± 0.032	1.887LysLeu: 1.887 ± 0.048	0.346LysMet: 0.346 ± 0.018	0.517LysAsn: 0.517 ± 0.026	1.186LysPro: 1.186 ± 0.036	0.704LysGln: 0.704 ± 0.028	1.58LysArg: 1.58 ± 0.04	1.242LysSer: 1.242 ± 0.03	1.241LysThr: 1.241 ± 0.039	1.699LysVal: 1.699 ± 0.045	0.241LysTrp: 0.241 ± 0.015	0.431LysTyr: 0.431 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	14.271LeuAla: 14.271 ± 0.147	0.484LeuCys: 0.484 ± 0.018	6.951LeuAsp: 6.951 ± 0.092	5.411LeuGlu: 5.411 ± 0.071	2.975LeuPhe: 2.975 ± 0.062	9.293LeuGly: 9.293 ± 0.106	1.893LeuHis: 1.893 ± 0.043	5.124LeuIle: 5.124 ± 0.082	1.857LeuLys: 1.857 ± 0.042	10.643LeuLeu: 10.643 ± 0.151	1.565LeuMet: 1.565 ± 0.037	1.888LeuAsn: 1.888 ± 0.047	5.597LeuPro: 5.597 ± 0.084	2.705LeuGln: 2.705 ± 0.054	7.225LeuArg: 7.225 ± 0.102	6.26LeuSer: 6.26 ± 0.091	6.127LeuThr: 6.127 ± 0.071	8.955LeuVal: 8.955 ± 0.12	1.156LeuTrp: 1.156 ± 0.033	1.67LeuTyr: 1.67 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.171MetAla: 2.171 ± 0.041	0.08MetCys: 0.08 ± 0.009	0.865MetAsp: 0.865 ± 0.027	0.655MetGlu: 0.655 ± 0.027	0.503MetPhe: 0.503 ± 0.02	1.268MetGly: 1.268 ± 0.032	0.342MetHis: 0.342 ± 0.017	0.87MetIle: 0.87 ± 0.031	0.393MetLys: 0.393 ± 0.021	1.796MetLeu: 1.796 ± 0.042	0.278MetMet: 0.278 ± 0.017	0.409MetAsn: 0.409 ± 0.019	1.155MetPro: 1.155 ± 0.034	0.528MetGln: 0.528 ± 0.019	1.331MetArg: 1.331 ± 0.033	1.51MetSer: 1.51 ± 0.037	1.622MetThr: 1.622 ± 0.042	1.26MetVal: 1.26 ± 0.032	0.178MetTrp: 0.178 ± 0.012	0.246MetTyr: 0.246 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.528AsnAla: 2.528 ± 0.047	0.116AsnCys: 0.116 ± 0.011	1.157AsnAsp: 1.157 ± 0.033	0.922AsnGlu: 0.922 ± 0.035	0.662AsnPhe: 0.662 ± 0.028	2.035AsnGly: 2.035 ± 0.051	0.347AsnHis: 0.347 ± 0.019	0.897AsnIle: 0.897 ± 0.035	0.348AsnLys: 0.348 ± 0.02	1.941AsnLeu: 1.941 ± 0.044	0.319AsnMet: 0.319 ± 0.018	0.465AsnAsn: 0.465 ± 0.025	1.532AsnPro: 1.532 ± 0.043	0.55AsnGln: 0.55 ± 0.027	1.342AsnArg: 1.342 ± 0.036	1.203AsnSer: 1.203 ± 0.038	1.094AsnThr: 1.094 ± 0.04	1.646AsnVal: 1.646 ± 0.043	0.326AsnTrp: 0.326 ± 0.016	0.486AsnTyr: 0.486 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.888ProAla: 6.888 ± 0.089	0.177ProCys: 0.177 ± 0.015	3.943ProAsp: 3.943 ± 0.064	3.496ProGlu: 3.496 ± 0.056	1.756ProPhe: 1.756 ± 0.04	4.743ProGly: 4.743 ± 0.065	1.04ProHis: 1.04 ± 0.031	2.695ProIle: 2.695 ± 0.049	1.084ProLys: 1.084 ± 0.038	4.782ProLeu: 4.782 ± 0.075	0.945ProMet: 0.945 ± 0.032	1.149ProAsn: 1.149 ± 0.031	2.406ProPro: 2.406 ± 0.063	1.466ProGln: 1.466 ± 0.04	3.307ProArg: 3.307 ± 0.063	3.688ProSer: 3.688 ± 0.057	3.716ProThr: 3.716 ± 0.059	4.61ProVal: 4.61 ± 0.071	0.813ProTrp: 0.813 ± 0.029	1.059ProTyr: 1.059 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.329GlnAla: 3.329 ± 0.058	0.109GlnCys: 0.109 ± 0.012	1.256GlnAsp: 1.256 ± 0.034	1.237GlnGlu: 1.237 ± 0.036	0.861GlnPhe: 0.861 ± 0.029	2.081GlnGly: 2.081 ± 0.048	0.608GlnHis: 0.608 ± 0.024	1.509GlnIle: 1.509 ± 0.039	0.68GlnLys: 0.68 ± 0.026	3.452GlnLeu: 3.452 ± 0.06	0.521GlnMet: 0.521 ± 0.019	0.611GlnAsn: 0.611 ± 0.027	1.583GlnPro: 1.583 ± 0.039	1.158GlnGln: 1.158 ± 0.037	2.381GlnArg: 2.381 ± 0.047	1.737GlnSer: 1.737 ± 0.041	1.576GlnThr: 1.576 ± 0.036	2.389GlnVal: 2.389 ± 0.045	0.432GlnTrp: 0.432 ± 0.019	0.593GlnTyr: 0.593 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	8.341ArgAla: 8.341 ± 0.104	0.256ArgCys: 0.256 ± 0.015	4.038ArgAsp: 4.038 ± 0.071	3.953ArgGlu: 3.953 ± 0.071	2.464ArgPhe: 2.464 ± 0.05	5.327ArgGly: 5.327 ± 0.079	1.483ArgHis: 1.483 ± 0.04	4.08ArgIle: 4.08 ± 0.067	1.393ArgLys: 1.393 ± 0.034	7.376ArgLeu: 7.376 ± 0.098	1.739ArgMet: 1.739 ± 0.038	1.349ArgAsn: 1.349 ± 0.032	3.689ArgPro: 3.689 ± 0.075	1.995ArgGln: 1.995 ± 0.048	6.381ArgArg: 6.381 ± 0.096	4.928ArgSer: 4.928 ± 0.079	4.128ArgThr: 4.128 ± 0.065	5.57ArgVal: 5.57 ± 0.071	1.093ArgTrp: 1.093 ± 0.036	1.494ArgTyr: 1.494 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	8.566SerAla: 8.566 ± 0.104	0.277SerCys: 0.277 ± 0.02	3.919SerAsp: 3.919 ± 0.063	3.135SerGlu: 3.135 ± 0.056	2.113SerPhe: 2.113 ± 0.05	6.56SerGly: 6.56 ± 0.086	1.101SerHis: 1.101 ± 0.03	3.274SerIle: 3.274 ± 0.06	1.242SerLys: 1.242 ± 0.037	5.924SerLeu: 5.924 ± 0.081	1.297SerMet: 1.297 ± 0.037	1.35SerAsn: 1.35 ± 0.042	3.406SerPro: 3.406 ± 0.061	1.629SerGln: 1.629 ± 0.035	4.253SerArg: 4.253 ± 0.055	4.847SerSer: 4.847 ± 0.094	4.515SerThr: 4.515 ± 0.087	5.318SerVal: 5.318 ± 0.073	0.945SerTrp: 0.945 ± 0.03	1.338SerTyr: 1.338 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	8.067ThrAla: 8.067 ± 0.099	0.234ThrCys: 0.234 ± 0.015	3.688ThrAsp: 3.688 ± 0.069	2.993ThrGlu: 2.993 ± 0.057	1.91ThrPhe: 1.91 ± 0.044	5.984ThrGly: 5.984 ± 0.09	0.962ThrHis: 0.962 ± 0.029	3.014ThrIle: 3.014 ± 0.055	1.19ThrLys: 1.19 ± 0.031	5.647ThrLeu: 5.647 ± 0.074	0.976ThrMet: 0.976 ± 0.032	1.208ThrAsn: 1.208 ± 0.031	3.786ThrPro: 3.786 ± 0.069	1.391ThrGln: 1.391 ± 0.04	3.654ThrArg: 3.654 ± 0.063	4.018ThrSer: 4.018 ± 0.084	3.925ThrThr: 3.925 ± 0.092	5.703ThrVal: 5.703 ± 0.081	0.781ThrTrp: 0.781 ± 0.026	1.112ThrTyr: 1.112 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	10.961ValAla: 10.961 ± 0.117	0.403ValCys: 0.403 ± 0.02	5.656ValAsp: 5.656 ± 0.076	4.612ValGlu: 4.612 ± 0.085	2.775ValPhe: 2.775 ± 0.043	7.457ValGly: 7.457 ± 0.086	1.53ValHis: 1.53 ± 0.037	4.388ValIle: 4.388 ± 0.064	1.483ValLys: 1.483 ± 0.038	9.439ValLeu: 9.439 ± 0.117	1.333ValMet: 1.333 ± 0.036	1.741ValAsn: 1.741 ± 0.042	4.528ValPro: 4.528 ± 0.058	2.276ValGln: 2.276 ± 0.048	5.73ValArg: 5.73 ± 0.073	5.269ValSer: 5.269 ± 0.069	5.45ValThr: 5.45 ± 0.081	8.267ValVal: 8.267 ± 0.113	1.019ValTrp: 1.019 ± 0.031	1.523ValTyr: 1.523 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.398TrpAla: 1.398 ± 0.038	0.071TrpCys: 0.071 ± 0.009	0.73TrpAsp: 0.73 ± 0.024	0.571TrpGlu: 0.571 ± 0.025	0.539TrpPhe: 0.539 ± 0.024	1.062TrpGly: 1.062 ± 0.033	0.311TrpHis: 0.311 ± 0.019	0.763TrpIle: 0.763 ± 0.028	0.366TrpLys: 0.366 ± 0.018	1.64TrpLeu: 1.64 ± 0.043	0.307TrpMet: 0.307 ± 0.016	0.419TrpAsn: 0.419 ± 0.02	0.696TrpPro: 0.696 ± 0.022	0.547TrpGln: 0.547 ± 0.026	1.123TrpArg: 1.123 ± 0.032	1.013TrpSer: 1.013 ± 0.032	0.938TrpThr: 0.938 ± 0.031	1.021TrpVal: 1.021 ± 0.029	0.321TrpTrp: 0.321 ± 0.017	0.287TrpTyr: 0.287 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.358TyrAla: 2.358 ± 0.051	0.124TyrCys: 0.124 ± 0.011	1.287TyrAsp: 1.287 ± 0.039	1.1TyrGlu: 1.1 ± 0.032	0.735TyrPhe: 0.735 ± 0.027	1.952TyrGly: 1.952 ± 0.043	0.294TyrHis: 0.294 ± 0.016	0.72TyrIle: 0.72 ± 0.027	0.351TyrLys: 0.351 ± 0.02	2.274TyrLeu: 2.274 ± 0.043	0.236TyrMet: 0.236 ± 0.014	0.448TyrAsn: 0.448 ± 0.019	1.021TyrPro: 1.021 ± 0.032	0.593TyrGln: 0.593 ± 0.026	1.611TyrArg: 1.611 ± 0.043	1.313TyrSer: 1.313 ± 0.035	1.125TyrThr: 1.125 ± 0.035	1.58TyrVal: 1.58 ± 0.04	0.313TyrTrp: 0.313 ± 0.017	0.469TyrTyr: 0.469 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3498 proteins (1124881 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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