Amino acid dipepetide frequency for Cytospora leucostoma

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.408AlaAla: 10.408 ± 0.08	0.981AlaCys: 0.981 ± 0.016	4.764AlaAsp: 4.764 ± 0.035	5.648AlaGlu: 5.648 ± 0.058	3.098AlaPhe: 3.098 ± 0.029	6.661AlaGly: 6.661 ± 0.044	1.854AlaHis: 1.854 ± 0.02	4.132AlaIle: 4.132 ± 0.031	4.177AlaLys: 4.177 ± 0.037	7.919AlaLeu: 7.919 ± 0.051	1.934AlaMet: 1.934 ± 0.02	2.943AlaAsn: 2.943 ± 0.031	5.191AlaPro: 5.191 ± 0.043	3.527AlaGln: 3.527 ± 0.034	5.425AlaArg: 5.425 ± 0.037	7.5AlaSer: 7.5 ± 0.044	5.697AlaThr: 5.697 ± 0.039	5.91AlaVal: 5.91 ± 0.035	1.245AlaTrp: 1.245 ± 0.017	2.243AlaTyr: 2.243 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.849CysAla: 0.849 ± 0.014	0.2CysCys: 0.2 ± 0.008	0.613CysAsp: 0.613 ± 0.012	0.543CysGlu: 0.543 ± 0.012	0.469CysPhe: 0.469 ± 0.009	0.881CysGly: 0.881 ± 0.016	0.292CysHis: 0.292 ± 0.008	0.61CysIle: 0.61 ± 0.012	0.433CysLys: 0.433 ± 0.01	1.093CysLeu: 1.093 ± 0.015	0.235CysMet: 0.235 ± 0.007	0.368CysAsn: 0.368 ± 0.01	0.596CysPro: 0.596 ± 0.013	0.386CysGln: 0.386 ± 0.009	0.651CysArg: 0.651 ± 0.012	0.774CysSer: 0.774 ± 0.013	0.592CysThr: 0.592 ± 0.012	0.726CysVal: 0.726 ± 0.013	0.181CysTrp: 0.181 ± 0.006	0.311CysTyr: 0.311 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.142AspAla: 5.142 ± 0.031	0.588AspCys: 0.588 ± 0.012	4.962AspAsp: 4.962 ± 0.046	4.873AspGlu: 4.873 ± 0.038	2.249AspPhe: 2.249 ± 0.024	4.678AspGly: 4.678 ± 0.034	1.306AspHis: 1.306 ± 0.019	3.005AspIle: 3.005 ± 0.028	2.457AspLys: 2.457 ± 0.026	5.245AspLeu: 5.245 ± 0.037	1.232AspMet: 1.232 ± 0.018	1.984AspAsn: 1.984 ± 0.021	3.484AspPro: 3.484 ± 0.026	1.887AspGln: 1.887 ± 0.018	3.136AspArg: 3.136 ± 0.031	4.041AspSer: 4.041 ± 0.027	3.107AspThr: 3.107 ± 0.025	3.954AspVal: 3.954 ± 0.031	0.926AspTrp: 0.926 ± 0.015	1.679AspTyr: 1.679 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	6.058GluAla: 6.058 ± 0.057	0.538GluCys: 0.538 ± 0.011	4.665GluAsp: 4.665 ± 0.033	5.716GluGlu: 5.716 ± 0.061	1.878GluPhe: 1.878 ± 0.021	4.181GluGly: 4.181 ± 0.037	1.427GluHis: 1.427 ± 0.018	2.777GluIle: 2.777 ± 0.024	3.572GluLys: 3.572 ± 0.04	5.256GluLeu: 5.256 ± 0.042	1.343GluMet: 1.343 ± 0.018	2.068GluAsn: 2.068 ± 0.023	2.985GluPro: 2.985 ± 0.034	2.529GluGln: 2.529 ± 0.026	4.023GluArg: 4.023 ± 0.034	3.963GluSer: 3.963 ± 0.034	3.464GluThr: 3.464 ± 0.028	3.961GluVal: 3.961 ± 0.028	0.894GluTrp: 0.894 ± 0.016	1.616GluTyr: 1.616 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.983PheAla: 2.983 ± 0.029	0.477PheCys: 0.477 ± 0.01	2.261PheAsp: 2.261 ± 0.022	2.123PheGlu: 2.123 ± 0.023	1.454PhePhe: 1.454 ± 0.02	2.83PheGly: 2.83 ± 0.031	0.835PheHis: 0.835 ± 0.012	1.677PheIle: 1.677 ± 0.022	1.438PheLys: 1.438 ± 0.017	3.258PheLeu: 3.258 ± 0.034	0.725PheMet: 0.725 ± 0.012	1.315PheAsn: 1.315 ± 0.016	1.821PhePro: 1.821 ± 0.018	1.297PheGln: 1.297 ± 0.017	1.916PheArg: 1.916 ± 0.022	2.742PheSer: 2.742 ± 0.028	2.051PheThr: 2.051 ± 0.022	2.354PheVal: 2.354 ± 0.025	0.612PheTrp: 0.612 ± 0.011	1.064PheTyr: 1.064 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	6.048GlyAla: 6.048 ± 0.049	0.812GlyCys: 0.812 ± 0.013	4.211GlyAsp: 4.211 ± 0.033	4.029GlyGlu: 4.029 ± 0.031	2.788GlyPhe: 2.788 ± 0.029	7.119GlyGly: 7.119 ± 0.071	1.844GlyHis: 1.844 ± 0.022	3.437GlyIle: 3.437 ± 0.03	3.427GlyLys: 3.427 ± 0.027	6.481GlyLeu: 6.481 ± 0.047	1.542GlyMet: 1.542 ± 0.019	2.599GlyAsn: 2.599 ± 0.027	3.751GlyPro: 3.751 ± 0.041	2.768GlyGln: 2.768 ± 0.028	4.51GlyArg: 4.51 ± 0.035	6.061GlySer: 6.061 ± 0.044	4.266GlyThr: 4.266 ± 0.031	4.65GlyVal: 4.65 ± 0.038	1.22GlyTrp: 1.22 ± 0.019	2.148GlyTyr: 2.148 ± 0.028	0.0GlyXaa: 0.0 ± 0.0
His	1.862HisAla: 1.862 ± 0.016	0.292HisCys: 0.292 ± 0.008	1.41HisAsp: 1.41 ± 0.016	1.331HisGlu: 1.331 ± 0.016	0.885HisPhe: 0.885 ± 0.014	1.799HisGly: 1.799 ± 0.019	0.894HisHis: 0.894 ± 0.018	1.178HisIle: 1.178 ± 0.017	0.936HisLys: 0.936 ± 0.016	2.168HisLeu: 2.168 ± 0.024	0.477HisMet: 0.477 ± 0.01	0.839HisAsn: 0.839 ± 0.013	1.61HisPro: 1.61 ± 0.02	0.965HisGln: 0.965 ± 0.015	1.511HisArg: 1.511 ± 0.021	1.661HisSer: 1.661 ± 0.022	1.212HisThr: 1.212 ± 0.015	1.464HisVal: 1.464 ± 0.017	0.342HisTrp: 0.342 ± 0.009	0.67HisTyr: 0.67 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.017IleAla: 4.017 ± 0.031	0.657IleCys: 0.657 ± 0.012	2.786IleAsp: 2.786 ± 0.026	2.74IleGlu: 2.74 ± 0.029	1.795IlePhe: 1.795 ± 0.019	3.065IleGly: 3.065 ± 0.03	1.064IleHis: 1.064 ± 0.017	2.35IleIle: 2.35 ± 0.025	2.059IleLys: 2.059 ± 0.022	4.2IleLeu: 4.2 ± 0.029	0.951IleMet: 0.951 ± 0.015	1.715IleAsn: 1.715 ± 0.018	2.84IlePro: 2.84 ± 0.026	1.715IleGln: 1.715 ± 0.022	2.663IleArg: 2.663 ± 0.024	3.519IleSer: 3.519 ± 0.027	2.769IleThr: 2.769 ± 0.027	3.041IleVal: 3.041 ± 0.027	0.714IleTrp: 0.714 ± 0.013	1.297IleTyr: 1.297 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.436LysAla: 4.436 ± 0.04	0.411LysCys: 0.411 ± 0.009	2.802LysAsp: 2.802 ± 0.026	3.32LysGlu: 3.32 ± 0.038	1.355LysPhe: 1.355 ± 0.018	3.035LysGly: 3.035 ± 0.028	1.104LysHis: 1.104 ± 0.017	2.051LysIle: 2.051 ± 0.024	3.278LysLys: 3.278 ± 0.049	3.896LysLeu: 3.896 ± 0.036	0.924LysMet: 0.924 ± 0.014	1.573LysAsn: 1.573 ± 0.019	2.674LysPro: 2.674 ± 0.031	1.804LysGln: 1.804 ± 0.023	3.288LysArg: 3.288 ± 0.033	3.217LysSer: 3.217 ± 0.029	2.779LysThr: 2.779 ± 0.028	2.872LysVal: 2.872 ± 0.025	0.645LysTrp: 0.645 ± 0.011	1.312LysTyr: 1.312 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.186LeuAla: 8.186 ± 0.052	1.064LeuCys: 1.064 ± 0.016	5.345LeuAsp: 5.345 ± 0.037	5.503LeuGlu: 5.503 ± 0.044	3.091LeuPhe: 3.091 ± 0.034	6.296LeuGly: 6.296 ± 0.045	2.119LeuHis: 2.119 ± 0.021	3.629LeuIle: 3.629 ± 0.03	4.024LeuLys: 4.024 ± 0.033	8.126LeuLeu: 8.126 ± 0.061	1.662LeuMet: 1.662 ± 0.02	2.941LeuAsn: 2.941 ± 0.027	5.419LeuPro: 5.419 ± 0.041	3.642LeuGln: 3.642 ± 0.032	5.823LeuArg: 5.823 ± 0.046	6.821LeuSer: 6.821 ± 0.044	4.742LeuThr: 4.742 ± 0.033	5.581LeuVal: 5.581 ± 0.04	1.217LeuTrp: 1.217 ± 0.017	2.29LeuTyr: 2.29 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.26MetAla: 2.26 ± 0.024	0.218MetCys: 0.218 ± 0.006	1.217MetAsp: 1.217 ± 0.017	1.179MetGlu: 1.179 ± 0.016	0.681MetPhe: 0.681 ± 0.012	1.428MetGly: 1.428 ± 0.017	0.431MetHis: 0.431 ± 0.01	0.862MetIle: 0.862 ± 0.015	0.853MetLys: 0.853 ± 0.015	1.703MetLeu: 1.703 ± 0.019	0.521MetMet: 0.521 ± 0.011	0.659MetAsn: 0.659 ± 0.013	1.224MetPro: 1.224 ± 0.015	0.769MetGln: 0.769 ± 0.013	1.229MetArg: 1.229 ± 0.017	1.791MetSer: 1.791 ± 0.023	1.222MetThr: 1.222 ± 0.017	1.284MetVal: 1.284 ± 0.018	0.253MetTrp: 0.253 ± 0.007	0.495MetTyr: 0.495 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.013AsnAla: 3.013 ± 0.029	0.385AsnCys: 0.385 ± 0.01	1.891AsnAsp: 1.891 ± 0.023	1.926AsnGlu: 1.926 ± 0.023	1.321AsnPhe: 1.321 ± 0.017	2.958AsnGly: 2.958 ± 0.029	0.812AsnHis: 0.812 ± 0.014	1.893AsnIle: 1.893 ± 0.023	1.538AsnLys: 1.538 ± 0.019	3.111AsnLeu: 3.111 ± 0.028	0.763AsnMet: 0.763 ± 0.014	1.534AsnAsn: 1.534 ± 0.025	2.274AsnPro: 2.274 ± 0.023	1.203AsnGln: 1.203 ± 0.017	1.798AsnArg: 1.798 ± 0.019	2.568AsnSer: 2.568 ± 0.025	2.176AsnThr: 2.176 ± 0.023	2.246AsnVal: 2.246 ± 0.023	0.534AsnTrp: 0.534 ± 0.011	1.02AsnTyr: 1.02 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.697ProAla: 5.697 ± 0.049	0.425ProCys: 0.425 ± 0.009	3.379ProAsp: 3.379 ± 0.027	3.951ProGlu: 3.951 ± 0.032	1.95ProPhe: 1.95 ± 0.02	4.428ProGly: 4.428 ± 0.039	1.299ProHis: 1.299 ± 0.017	2.391ProIle: 2.391 ± 0.026	2.604ProLys: 2.604 ± 0.027	4.616ProLeu: 4.616 ± 0.032	1.02ProMet: 1.02 ± 0.016	2.067ProAsn: 2.067 ± 0.024	5.318ProPro: 5.318 ± 0.079	2.567ProGln: 2.567 ± 0.033	3.651ProArg: 3.651 ± 0.038	5.687ProSer: 5.687 ± 0.057	3.983ProThr: 3.983 ± 0.034	3.766ProVal: 3.766 ± 0.029	0.754ProTrp: 0.754 ± 0.013	1.535ProTyr: 1.535 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.686GlnAla: 3.686 ± 0.033	0.385GlnCys: 0.385 ± 0.011	2.152GlnAsp: 2.152 ± 0.022	2.438GlnGlu: 2.438 ± 0.024	1.146GlnPhe: 1.146 ± 0.015	2.513GlnGly: 2.513 ± 0.024	1.109GlnHis: 1.109 ± 0.019	1.69GlnIle: 1.69 ± 0.021	1.844GlnLys: 1.844 ± 0.023	3.36GlnLeu: 3.36 ± 0.034	0.813GlnMet: 0.813 ± 0.014	1.357GlnAsn: 1.357 ± 0.019	2.616GlnPro: 2.616 ± 0.037	2.719GlnGln: 2.719 ± 0.06	2.692GlnArg: 2.692 ± 0.028	2.888GlnSer: 2.888 ± 0.028	2.187GlnThr: 2.187 ± 0.024	2.279GlnVal: 2.279 ± 0.022	0.565GlnTrp: 0.565 ± 0.011	1.131GlnTyr: 1.131 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.085ArgAla: 5.085 ± 0.036	0.622ArgCys: 0.622 ± 0.012	3.593ArgAsp: 3.593 ± 0.032	3.968ArgGlu: 3.968 ± 0.038	2.064ArgPhe: 2.064 ± 0.02	4.084ArgGly: 4.084 ± 0.036	1.571ArgHis: 1.571 ± 0.019	2.757ArgIle: 2.757 ± 0.022	3.394ArgLys: 3.394 ± 0.031	5.581ArgLeu: 5.581 ± 0.041	1.258ArgMet: 1.258 ± 0.017	2.19ArgAsn: 2.19 ± 0.02	3.737ArgPro: 3.737 ± 0.039	2.669ArgGln: 2.669 ± 0.027	5.359ArgArg: 5.359 ± 0.046	4.652ArgSer: 4.652 ± 0.043	3.244ArgThr: 3.244 ± 0.024	3.513ArgVal: 3.513 ± 0.03	0.947ArgTrp: 0.947 ± 0.013	1.659ArgTyr: 1.659 ± 0.021	0.0ArgXaa: 0.0 ± 0.0
Ser	6.814SerAla: 6.814 ± 0.05	0.75SerCys: 0.75 ± 0.014	4.163SerAsp: 4.163 ± 0.033	3.945SerGlu: 3.945 ± 0.029	2.757SerPhe: 2.757 ± 0.028	5.871SerGly: 5.871 ± 0.047	1.804SerHis: 1.804 ± 0.02	3.653SerIle: 3.653 ± 0.03	3.454SerLys: 3.454 ± 0.033	6.758SerLeu: 6.758 ± 0.041	1.566SerMet: 1.566 ± 0.019	2.811SerAsn: 2.811 ± 0.028	5.373SerPro: 5.373 ± 0.058	3.104SerGln: 3.104 ± 0.029	4.873SerArg: 4.873 ± 0.039	8.67SerSer: 8.67 ± 0.092	5.445SerThr: 5.445 ± 0.044	4.545SerVal: 4.545 ± 0.032	1.084SerTrp: 1.084 ± 0.015	2.02SerTyr: 2.02 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.582ThrAla: 5.582 ± 0.036	0.655ThrCys: 0.655 ± 0.011	2.99ThrAsp: 2.99 ± 0.023	3.193ThrGlu: 3.193 ± 0.028	2.127ThrPhe: 2.127 ± 0.022	4.464ThrGly: 4.464 ± 0.032	1.206ThrHis: 1.206 ± 0.015	2.982ThrIle: 2.982 ± 0.025	2.589ThrLys: 2.589 ± 0.024	4.984ThrLeu: 4.984 ± 0.041	1.114ThrMet: 1.114 ± 0.016	2.094ThrAsn: 2.094 ± 0.02	4.294ThrPro: 4.294 ± 0.036	2.042ThrGln: 2.042 ± 0.023	3.2ThrArg: 3.2 ± 0.029	5.349ThrSer: 5.349 ± 0.048	4.648ThrThr: 4.648 ± 0.051	3.882ThrVal: 3.882 ± 0.034	0.848ThrTrp: 0.848 ± 0.013	1.619ThrTyr: 1.619 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.768ValAla: 5.768 ± 0.036	0.762ValCys: 0.762 ± 0.014	4.034ValAsp: 4.034 ± 0.031	4.038ValGlu: 4.038 ± 0.035	2.447ValPhe: 2.447 ± 0.023	4.3ValGly: 4.3 ± 0.036	1.43ValHis: 1.43 ± 0.017	2.9ValIle: 2.9 ± 0.028	2.873ValLys: 2.873 ± 0.029	5.848ValLeu: 5.848 ± 0.038	1.238ValMet: 1.238 ± 0.013	2.182ValAsn: 2.182 ± 0.025	3.819ValPro: 3.819 ± 0.034	2.373ValGln: 2.373 ± 0.021	3.63ValArg: 3.63 ± 0.032	4.562ValSer: 4.562 ± 0.032	3.736ValThr: 3.736 ± 0.034	4.696ValVal: 4.696 ± 0.038	0.896ValTrp: 0.896 ± 0.013	1.775ValTyr: 1.775 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.211TrpAla: 1.211 ± 0.017	0.19TrpCys: 0.19 ± 0.006	0.964TrpAsp: 0.964 ± 0.014	0.869TrpGlu: 0.869 ± 0.013	0.532TrpPhe: 0.532 ± 0.01	0.975TrpGly: 0.975 ± 0.015	0.352TrpHis: 0.352 ± 0.008	0.665TrpIle: 0.665 ± 0.013	0.752TrpLys: 0.752 ± 0.012	1.359TrpLeu: 1.359 ± 0.019	0.367TrpMet: 0.367 ± 0.008	0.599TrpAsn: 0.599 ± 0.013	0.634TrpPro: 0.634 ± 0.011	0.564TrpGln: 0.564 ± 0.011	0.991TrpArg: 0.991 ± 0.014	1.013TrpSer: 1.013 ± 0.015	0.931TrpThr: 0.931 ± 0.013	0.916TrpVal: 0.916 ± 0.014	0.284TrpTrp: 0.284 ± 0.009	0.451TrpTyr: 0.451 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.151TyrAla: 2.151 ± 0.024	0.389TyrCys: 0.389 ± 0.009	1.736TyrAsp: 1.736 ± 0.019	1.58TyrGlu: 1.58 ± 0.018	1.148TyrPhe: 1.148 ± 0.017	2.145TyrGly: 2.145 ± 0.023	0.754TyrHis: 0.754 ± 0.011	1.318TyrIle: 1.318 ± 0.019	1.075TyrLys: 1.075 ± 0.015	2.559TyrLeu: 2.559 ± 0.025	0.593TyrMet: 0.593 ± 0.011	1.126TyrAsn: 1.126 ± 0.017	1.428TyrPro: 1.428 ± 0.019	1.04TyrGln: 1.04 ± 0.015	1.576TyrArg: 1.576 ± 0.02	1.982TyrSer: 1.982 ± 0.022	1.612TyrThr: 1.612 ± 0.018	1.665TyrVal: 1.665 ± 0.017	0.458TyrTrp: 0.458 ± 0.01	0.956TyrTyr: 0.956 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 10071 proteins (5010871 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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