Amino acid dipepetide frequency for Trichechus manatus papillomavirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.849AlaAla: 6.849 ± 0.879
2.14AlaCys: 2.14 ± 1.919
3.853AlaAsp: 3.853 ± 1.026
4.281AlaGlu: 4.281 ± 1.274
2.14AlaPhe: 2.14 ± 0.622
5.565AlaGly: 5.565 ± 1.294
0.428AlaHis: 0.428 ± 0.385
1.712AlaIle: 1.712 ± 0.227
2.997AlaLys: 2.997 ± 0.963
3.853AlaLeu: 3.853 ± 1.308
0.856AlaMet: 0.856 ± 0.697
2.14AlaAsn: 2.14 ± 1.005
2.568AlaPro: 2.568 ± 0.971
3.425AlaGln: 3.425 ± 0.453
2.997AlaArg: 2.997 ± 1.01
2.568AlaSer: 2.568 ± 0.422
5.137AlaThr: 5.137 ± 0.865
2.997AlaVal: 2.997 ± 0.563
0.856AlaTrp: 0.856 ± 0.422
2.997AlaTyr: 2.997 ± 1.01
0.0AlaXaa: 0.0 ± 0.0
Cys
0.428CysAla: 0.428 ± 0.341
1.284CysCys: 1.284 ± 0.919
1.712CysAsp: 1.712 ± 0.888
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.284CysGly: 1.284 ± 0.808
0.428CysHis: 0.428 ± 0.341
2.997CysIle: 2.997 ± 1.435
2.568CysLys: 2.568 ± 1.0
2.14CysLeu: 2.14 ± 1.23
0.428CysMet: 0.428 ± 0.341
0.428CysAsn: 0.428 ± 0.62
3.425CysPro: 3.425 ± 1.808
1.712CysGln: 1.712 ± 0.774
1.284CysArg: 1.284 ± 0.65
2.568CysSer: 2.568 ± 1.443
0.856CysThr: 0.856 ± 0.433
0.856CysVal: 0.856 ± 0.608
0.428CysTrp: 0.428 ± 0.341
0.428CysTyr: 0.428 ± 0.385
0.0CysXaa: 0.0 ± 0.0
Asp
3.853AspAla: 3.853 ± 1.24
0.856AspCys: 0.856 ± 0.433
2.568AspAsp: 2.568 ± 0.659
3.425AspGlu: 3.425 ± 1.227
4.709AspPhe: 4.709 ± 1.246
4.709AspGly: 4.709 ± 1.21
1.284AspHis: 1.284 ± 0.647
4.281AspIle: 4.281 ± 1.096
2.14AspLys: 2.14 ± 1.038
4.709AspLeu: 4.709 ± 1.066
0.428AspMet: 0.428 ± 0.349
3.425AspAsn: 3.425 ± 0.586
5.137AspPro: 5.137 ± 1.23
2.568AspGln: 2.568 ± 0.967
2.997AspArg: 2.997 ± 0.836
6.421AspSer: 6.421 ± 1.964
3.425AspThr: 3.425 ± 0.985
4.281AspVal: 4.281 ± 0.816
0.428AspTrp: 0.428 ± 0.341
2.14AspTyr: 2.14 ± 0.918
0.0AspXaa: 0.0 ± 0.0
Glu
3.853GluAla: 3.853 ± 1.067
1.712GluCys: 1.712 ± 0.819
5.137GluAsp: 5.137 ± 1.568
5.993GluGlu: 5.993 ± 1.811
1.712GluPhe: 1.712 ± 0.607
2.568GluGly: 2.568 ± 0.675
0.856GluHis: 0.856 ± 0.427
2.997GluIle: 2.997 ± 2.188
1.284GluLys: 1.284 ± 0.65
6.421GluLeu: 6.421 ± 1.554
1.284GluMet: 1.284 ± 0.678
2.997GluAsn: 2.997 ± 0.722
1.284GluPro: 1.284 ± 0.681
2.568GluGln: 2.568 ± 0.575
3.425GluArg: 3.425 ± 1.207
5.565GluSer: 5.565 ± 0.843
2.997GluThr: 2.997 ± 1.04
5.137GluVal: 5.137 ± 1.117
1.284GluTrp: 1.284 ± 0.684
0.856GluTyr: 0.856 ± 0.445
0.0GluXaa: 0.0 ± 0.0
Phe
1.284PheAla: 1.284 ± 1.024
0.856PheCys: 0.856 ± 0.608
4.281PheAsp: 4.281 ± 0.946
2.568PheGlu: 2.568 ± 1.226
2.568PhePhe: 2.568 ± 0.983
3.425PheGly: 3.425 ± 1.165
0.0PheHis: 0.0 ± 0.0
2.14PheIle: 2.14 ± 0.917
1.284PheLys: 1.284 ± 1.024
4.709PheLeu: 4.709 ± 1.043
0.856PheMet: 0.856 ± 0.592
2.14PheAsn: 2.14 ± 0.689
1.284PhePro: 1.284 ± 0.445
0.428PheGln: 0.428 ± 0.349
1.284PheArg: 1.284 ± 0.646
2.997PheSer: 2.997 ± 0.757
2.997PheThr: 2.997 ± 0.757
1.284PheVal: 1.284 ± 0.647
0.856PheTrp: 0.856 ± 0.422
1.712PheTyr: 1.712 ± 0.626
0.0PheXaa: 0.0 ± 0.0
Gly
4.281GlyAla: 4.281 ± 1.533
2.568GlyCys: 2.568 ± 0.974
4.281GlyAsp: 4.281 ± 1.331
3.425GlyGlu: 3.425 ± 0.719
1.284GlyPhe: 1.284 ± 0.445
8.134GlyGly: 8.134 ± 2.661
2.568GlyHis: 2.568 ± 0.614
2.14GlyIle: 2.14 ± 0.684
3.425GlyLys: 3.425 ± 0.518
3.853GlyLeu: 3.853 ± 1.035
0.0GlyMet: 0.0 ± 0.0
2.997GlyAsn: 2.997 ± 1.476
2.568GlyPro: 2.568 ± 0.582
2.14GlyGln: 2.14 ± 0.468
5.137GlyArg: 5.137 ± 1.381
3.425GlySer: 3.425 ± 0.8
7.277GlyThr: 7.277 ± 1.855
4.281GlyVal: 4.281 ± 1.039
1.284GlyTrp: 1.284 ± 0.628
1.712GlyTyr: 1.712 ± 0.607
0.0GlyXaa: 0.0 ± 0.0
His
1.712HisAla: 1.712 ± 0.891
2.14HisCys: 2.14 ± 0.959
0.0HisAsp: 0.0 ± 0.0
0.428HisGlu: 0.428 ± 0.385
1.284HisPhe: 1.284 ± 0.358
0.856HisGly: 0.856 ± 0.359
0.428HisHis: 0.428 ± 0.341
1.712HisIle: 1.712 ± 0.609
0.428HisLys: 0.428 ± 0.385
2.568HisLeu: 2.568 ± 0.659
0.428HisMet: 0.428 ± 0.373
0.428HisAsn: 0.428 ± 0.349
2.14HisPro: 2.14 ± 1.226
1.284HisGln: 1.284 ± 0.684
0.428HisArg: 0.428 ± 0.341
0.428HisSer: 0.428 ± 0.373
1.712HisThr: 1.712 ± 0.533
1.284HisVal: 1.284 ± 0.65
0.428HisTrp: 0.428 ± 0.349
1.712HisTyr: 1.712 ± 0.819
0.0HisXaa: 0.0 ± 0.0
Ile
2.568IleAla: 2.568 ± 0.445
1.284IleCys: 1.284 ± 0.646
3.425IleAsp: 3.425 ± 1.214
2.14IleGlu: 2.14 ± 0.8
1.284IlePhe: 1.284 ± 0.445
4.281IleGly: 4.281 ± 1.73
1.712IleHis: 1.712 ± 0.996
2.14IleIle: 2.14 ± 1.62
0.856IleLys: 0.856 ± 0.433
5.137IleLeu: 5.137 ± 0.813
0.428IleMet: 0.428 ± 0.349
1.284IleAsn: 1.284 ± 0.647
2.14IlePro: 2.14 ± 1.216
2.14IleGln: 2.14 ± 0.626
2.14IleArg: 2.14 ± 1.273
5.565IleSer: 5.565 ± 2.121
4.281IleThr: 4.281 ± 0.794
1.712IleVal: 1.712 ± 0.609
0.428IleTrp: 0.428 ± 0.566
2.14IleTyr: 2.14 ± 1.102
0.0IleXaa: 0.0 ± 0.0
Lys
1.284LysAla: 1.284 ± 0.373
2.14LysCys: 2.14 ± 1.008
1.712LysAsp: 1.712 ± 0.978
0.856LysGlu: 0.856 ± 0.427
2.14LysPhe: 2.14 ± 1.038
2.14LysGly: 2.14 ± 1.153
0.856LysHis: 0.856 ± 0.433
0.856LysIle: 0.856 ± 0.422
2.14LysLys: 2.14 ± 1.305
2.14LysLeu: 2.14 ± 1.19
1.284LysMet: 1.284 ± 0.95
2.14LysAsn: 2.14 ± 1.305
1.712LysPro: 1.712 ± 0.616
3.853LysGln: 3.853 ± 1.217
5.565LysArg: 5.565 ± 1.342
1.712LysSer: 1.712 ± 0.616
2.14LysThr: 2.14 ± 1.085
2.568LysVal: 2.568 ± 0.959
1.284LysTrp: 1.284 ± 0.673
2.14LysTyr: 2.14 ± 1.35
0.0LysXaa: 0.0 ± 0.0
Leu
4.281LeuAla: 4.281 ± 0.98
2.568LeuCys: 2.568 ± 1.77
7.277LeuAsp: 7.277 ± 1.223
4.709LeuGlu: 4.709 ± 1.378
2.997LeuPhe: 2.997 ± 0.972
8.134LeuGly: 8.134 ± 1.111
2.14LeuHis: 2.14 ± 1.348
2.568LeuIle: 2.568 ± 0.816
3.853LeuLys: 3.853 ± 0.833
11.986LeuLeu: 11.986 ± 2.07
1.284LeuMet: 1.284 ± 0.633
2.14LeuAsn: 2.14 ± 0.733
4.709LeuPro: 4.709 ± 1.181
5.137LeuGln: 5.137 ± 0.93
5.137LeuArg: 5.137 ± 1.774
5.993LeuSer: 5.993 ± 0.688
5.565LeuThr: 5.565 ± 1.427
5.137LeuVal: 5.137 ± 1.024
0.428LeuTrp: 0.428 ± 0.341
1.712LeuTyr: 1.712 ± 0.54
0.0LeuXaa: 0.0 ± 0.0
Met
0.428MetAla: 0.428 ± 0.349
0.0MetCys: 0.0 ± 0.0
1.712MetAsp: 1.712 ± 0.99
0.856MetGlu: 0.856 ± 0.769
0.0MetPhe: 0.0 ± 0.0
0.856MetGly: 0.856 ± 0.697
0.428MetHis: 0.428 ± 0.341
0.428MetIle: 0.428 ± 0.62
0.0MetLys: 0.0 ± 0.0
2.14MetLeu: 2.14 ± 1.322
0.428MetMet: 0.428 ± 0.385
0.856MetAsn: 0.856 ± 0.608
0.856MetPro: 0.856 ± 0.359
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
2.14MetSer: 2.14 ± 1.019
0.428MetThr: 0.428 ± 0.349
1.712MetVal: 1.712 ± 0.898
0.0MetTrp: 0.0 ± 0.0
0.428MetTyr: 0.428 ± 0.349
0.0MetXaa: 0.0 ± 0.0
Asn
1.284AsnAla: 1.284 ± 1.024
0.856AsnCys: 0.856 ± 0.683
2.568AsnAsp: 2.568 ± 0.813
2.14AsnGlu: 2.14 ± 1.223
1.712AsnPhe: 1.712 ± 1.45
0.428AsnGly: 0.428 ± 0.349
0.0AsnHis: 0.0 ± 0.0
2.568AsnIle: 2.568 ± 0.422
0.856AsnLys: 0.856 ± 0.649
2.568AsnLeu: 2.568 ± 1.106
0.428AsnMet: 0.428 ± 0.341
2.14AsnAsn: 2.14 ± 0.455
4.709AsnPro: 4.709 ± 1.695
0.856AsnGln: 0.856 ± 0.427
3.853AsnArg: 3.853 ± 1.289
4.281AsnSer: 4.281 ± 1.025
4.281AsnThr: 4.281 ± 1.54
2.568AsnVal: 2.568 ± 0.805
0.0AsnTrp: 0.0 ± 0.0
0.856AsnTyr: 0.856 ± 0.649
0.0AsnXaa: 0.0 ± 0.0
Pro
6.421ProAla: 6.421 ± 2.228
1.284ProCys: 1.284 ± 0.847
5.993ProAsp: 5.993 ± 1.238
6.421ProGlu: 6.421 ± 1.441
0.856ProPhe: 0.856 ± 0.683
2.568ProGly: 2.568 ± 0.582
2.14ProHis: 2.14 ± 1.395
2.997ProIle: 2.997 ± 1.7
1.712ProLys: 1.712 ± 0.616
5.565ProLeu: 5.565 ± 2.556
0.428ProMet: 0.428 ± 0.341
1.712ProAsn: 1.712 ± 0.803
6.849ProPro: 6.849 ± 1.895
1.284ProGln: 1.284 ± 0.695
3.853ProArg: 3.853 ± 0.661
3.853ProSer: 3.853 ± 1.653
4.709ProThr: 4.709 ± 1.447
4.709ProVal: 4.709 ± 1.168
0.856ProTrp: 0.856 ± 0.649
2.568ProTyr: 2.568 ± 1.021
0.0ProXaa: 0.0 ± 0.0
Gln
2.14GlnAla: 2.14 ± 0.926
0.0GlnCys: 0.0 ± 0.0
1.284GlnAsp: 1.284 ± 0.445
2.997GlnGlu: 2.997 ± 1.276
1.284GlnPhe: 1.284 ± 0.695
2.997GlnGly: 2.997 ± 0.608
0.428GlnHis: 0.428 ± 0.341
2.14GlnIle: 2.14 ± 0.712
1.712GlnLys: 1.712 ± 0.664
2.997GlnLeu: 2.997 ± 0.805
1.284GlnMet: 1.284 ± 0.392
2.568GlnAsn: 2.568 ± 0.992
2.568GlnPro: 2.568 ± 1.391
1.284GlnGln: 1.284 ± 0.358
4.281GlnArg: 4.281 ± 1.343
4.281GlnSer: 4.281 ± 0.665
3.425GlnThr: 3.425 ± 0.439
1.284GlnVal: 1.284 ± 0.847
1.712GlnTrp: 1.712 ± 0.774
2.14GlnTyr: 2.14 ± 1.225
0.0GlnXaa: 0.0 ± 0.0
Arg
2.997ArgAla: 2.997 ± 0.937
2.14ArgCys: 2.14 ± 1.23
2.997ArgAsp: 2.997 ± 0.7
2.568ArgGlu: 2.568 ± 0.817
2.14ArgPhe: 2.14 ± 0.716
5.993ArgGly: 5.993 ± 2.172
2.14ArgHis: 2.14 ± 0.455
2.997ArgIle: 2.997 ± 0.897
4.709ArgLys: 4.709 ± 0.971
5.993ArgLeu: 5.993 ± 1.297
0.0ArgMet: 0.0 ± 0.0
2.14ArgAsn: 2.14 ± 1.019
5.993ArgPro: 5.993 ± 1.554
1.712ArgGln: 1.712 ± 0.892
5.993ArgArg: 5.993 ± 2.699
2.14ArgSer: 2.14 ± 0.918
4.281ArgThr: 4.281 ± 1.503
4.281ArgVal: 4.281 ± 0.584
1.712ArgTrp: 1.712 ± 0.845
2.997ArgTyr: 2.997 ± 1.01
0.0ArgXaa: 0.0 ± 0.0
Ser
2.14SerAla: 2.14 ± 1.155
0.856SerCys: 0.856 ± 0.476
4.709SerAsp: 4.709 ± 0.694
5.137SerGlu: 5.137 ± 0.749
5.565SerPhe: 5.565 ± 1.365
5.137SerGly: 5.137 ± 1.006
1.284SerHis: 1.284 ± 0.358
5.993SerIle: 5.993 ± 1.871
2.568SerLys: 2.568 ± 1.243
5.565SerLeu: 5.565 ± 0.783
0.428SerMet: 0.428 ± 0.341
2.997SerAsn: 2.997 ± 1.175
5.993SerPro: 5.993 ± 0.864
3.425SerGln: 3.425 ± 1.215
4.281SerArg: 4.281 ± 0.726
4.281SerSer: 4.281 ± 1.564
6.849SerThr: 6.849 ± 3.162
2.997SerVal: 2.997 ± 0.85
0.856SerTrp: 0.856 ± 0.433
1.712SerTyr: 1.712 ± 0.6
0.0SerXaa: 0.0 ± 0.0
Thr
5.137ThrAla: 5.137 ± 1.646
1.712ThrCys: 1.712 ± 0.533
5.137ThrAsp: 5.137 ± 1.801
3.853ThrGlu: 3.853 ± 0.746
2.568ThrPhe: 2.568 ± 0.933
2.997ThrGly: 2.997 ± 1.337
1.712ThrHis: 1.712 ± 0.597
2.14ThrIle: 2.14 ± 0.928
4.281ThrLys: 4.281 ± 0.975
7.277ThrLeu: 7.277 ± 1.64
0.856ThrMet: 0.856 ± 0.683
2.14ThrAsn: 2.14 ± 0.928
5.137ThrPro: 5.137 ± 2.017
2.997ThrGln: 2.997 ± 0.834
5.565ThrArg: 5.565 ± 0.828
8.562ThrSer: 8.562 ± 2.67
6.421ThrThr: 6.421 ± 2.463
5.993ThrVal: 5.993 ± 1.693
1.284ThrTrp: 1.284 ± 0.744
1.712ThrTyr: 1.712 ± 0.579
0.0ThrXaa: 0.0 ± 0.0
Val
5.137ValAla: 5.137 ± 1.332
0.0ValCys: 0.0 ± 0.0
2.568ValAsp: 2.568 ± 0.805
5.137ValGlu: 5.137 ± 1.541
2.14ValPhe: 2.14 ± 0.73
2.14ValGly: 2.14 ± 0.804
1.712ValHis: 1.712 ± 0.952
1.712ValIle: 1.712 ± 0.717
1.712ValLys: 1.712 ± 1.365
5.565ValLeu: 5.565 ± 2.116
1.284ValMet: 1.284 ± 0.401
2.14ValAsn: 2.14 ± 0.777
6.849ValPro: 6.849 ± 2.094
2.997ValGln: 2.997 ± 1.37
3.425ValArg: 3.425 ± 1.071
2.14ValSer: 2.14 ± 0.689
5.565ValThr: 5.565 ± 1.494
2.568ValVal: 2.568 ± 1.427
0.856ValTrp: 0.856 ± 0.427
2.14ValTyr: 2.14 ± 0.733
0.0ValXaa: 0.0 ± 0.0
Trp
2.568TrpAla: 2.568 ± 1.255
0.428TrpCys: 0.428 ± 0.566
0.428TrpAsp: 0.428 ± 0.385
0.856TrpGlu: 0.856 ± 0.433
0.0TrpPhe: 0.0 ± 0.0
0.428TrpGly: 0.428 ± 0.349
0.428TrpHis: 0.428 ± 0.349
0.856TrpIle: 0.856 ± 0.359
1.284TrpLys: 1.284 ± 0.403
1.712TrpLeu: 1.712 ± 0.612
0.428TrpMet: 0.428 ± 0.503
0.856TrpAsn: 0.856 ± 0.422
0.0TrpPro: 0.0 ± 0.0
0.856TrpGln: 0.856 ± 0.649
1.712TrpArg: 1.712 ± 0.845
0.0TrpSer: 0.0 ± 0.0
1.712TrpThr: 1.712 ± 0.664
1.284TrpVal: 1.284 ± 1.024
0.428TrpTrp: 0.428 ± 0.566
0.428TrpTyr: 0.428 ± 0.341
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.712TyrAla: 1.712 ± 0.664
0.428TyrCys: 0.428 ± 0.62
2.14TyrAsp: 2.14 ± 0.717
2.14TyrGlu: 2.14 ± 0.468
2.568TyrPhe: 2.568 ± 0.528
2.14TyrGly: 2.14 ± 0.423
0.856TyrHis: 0.856 ± 0.422
1.712TyrIle: 1.712 ± 0.579
1.284TyrLys: 1.284 ± 0.403
0.856TyrLeu: 0.856 ± 0.64
0.428TyrMet: 0.428 ± 0.341
1.284TyrAsn: 1.284 ± 0.757
0.856TyrPro: 0.856 ± 0.445
2.14TyrGln: 2.14 ± 0.423
2.568TyrArg: 2.568 ± 0.575
3.853TyrSer: 3.853 ± 1.168
3.425TyrThr: 3.425 ± 1.067
0.856TyrVal: 0.856 ± 0.683
1.284TyrTrp: 1.284 ± 0.403
2.14TyrTyr: 2.14 ± 1.462
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2337 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski