Streptococcus thermophilus CNCM I-1630

Taxonomy: cellular organisms; Bacteria; Terrabacteria group; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus thermophilus

Average proteome isoelectric point is 6.39

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1889 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|G6END5|G6END5_STRTR tRNA pseudouridine(38-40) synthase OS=Streptococcus thermophilus CNCM I-1630 OX=1042404 GN=STHE1630_00631 PE=4 SV=1
MM1 pKa = 7.43LLIVQLLLLASQLSYY16 pKa = 10.69EE17 pKa = 4.17LHH19 pKa = 6.53DD20 pKa = 3.88TQSAEE25 pKa = 4.27SYY27 pKa = 10.44LKK29 pKa = 10.27QALPLAEE36 pKa = 5.27DD37 pKa = 3.3NDD39 pKa = 4.4EE40 pKa = 4.07IVLRR44 pKa = 11.84LSALYY49 pKa = 10.64LEE51 pKa = 5.01EE52 pKa = 4.66EE53 pKa = 4.31RR54 pKa = 11.84FDD56 pKa = 5.05DD57 pKa = 5.38LVALADD63 pKa = 3.9YY64 pKa = 10.65EE65 pKa = 4.37VDD67 pKa = 3.63SVLARR72 pKa = 11.84WNIARR77 pKa = 11.84AYY79 pKa = 9.59QALDD83 pKa = 3.49DD84 pKa = 4.43EE85 pKa = 5.11EE86 pKa = 4.83EE87 pKa = 4.26AFQIYY92 pKa = 10.18QDD94 pKa = 4.05LSKK97 pKa = 11.23DD98 pKa = 3.43LADD101 pKa = 4.01NPEE104 pKa = 3.73FLQDD108 pKa = 3.08YY109 pKa = 10.35AYY111 pKa = 9.97ILRR114 pKa = 11.84EE115 pKa = 3.54FGYY118 pKa = 10.32RR119 pKa = 11.84DD120 pKa = 3.43QARR123 pKa = 11.84VTAEE127 pKa = 4.0KK128 pKa = 10.86YY129 pKa = 10.18LALVPDD135 pKa = 4.67DD136 pKa = 5.26VNMQTFLEE144 pKa = 5.16DD145 pKa = 3.44YY146 pKa = 10.9

Molecular weight: 17.01 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|G6ELS3|G6ELS3_STRTR Spermidine/putrescine-binding protein (Fragment) OS=Streptococcus thermophilus CNCM I-1630 OX=1042404 GN=STHE1630_00061 PE=4 SV=1
MM1 pKa = 7.6KK2 pKa = 10.2ISGKK6 pKa = 10.04IPGGYY11 pKa = 9.91DD12 pKa = 3.34GNHH15 pKa = 7.38LIAISSSRR23 pKa = 11.84ILIEE27 pKa = 4.07FWLTRR32 pKa = 11.84RR33 pKa = 11.84KK34 pKa = 10.16RR35 pKa = 11.84FICLRR40 pKa = 11.84PKK42 pKa = 9.38STSARR47 pKa = 11.84EE48 pKa = 3.96QRR50 pKa = 11.84CGAFKK55 pKa = 11.08LFGPGGNDD63 pKa = 3.4PTDD66 pKa = 3.48SGAKK70 pKa = 8.85RR71 pKa = 11.84VYY73 pKa = 10.0TSGLASFAIFEE84 pKa = 4.59SYY86 pKa = 10.29RR87 pKa = 11.84KK88 pKa = 9.74RR89 pKa = 11.84GLHH92 pKa = 6.49GYY94 pKa = 9.9GGG96 pKa = 3.58

Molecular weight: 10.59 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1889

0

1889

393498

20

1217

208.3

23.41

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.23 ± 0.07

0.638 ± 0.019

5.835 ± 0.055

6.806 ± 0.072

4.574 ± 0.05

6.481 ± 0.05

1.937 ± 0.027

7.346 ± 0.058

6.9 ± 0.062

9.885 ± 0.08

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.577 ± 0.03

4.656 ± 0.044

3.325 ± 0.031

3.826 ± 0.04

4.276 ± 0.051

6.324 ± 0.058

5.707 ± 0.045

6.956 ± 0.052

0.879 ± 0.021

3.832 ± 0.045
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski