MW polyomavirus

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Sepolyvirales; Polyomaviridae; Deltapolyomavirus; Human polyomavirus 10

Average proteome isoelectric point is 5.5

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|I6UY22|I6UY22_9POLY Large T antigen OS=MW polyomavirus OX=1203539 PE=4 SV=1
MM1 pKa = 7.29GAVISVILDD10 pKa = 4.3LIEE13 pKa = 5.14LISVTGFEE21 pKa = 4.71AEE23 pKa = 4.31TIISGEE29 pKa = 3.54AAAIVEE35 pKa = 4.52SQLSSLAVIEE45 pKa = 4.31NASAAEE51 pKa = 3.99VLSTFGLNEE60 pKa = 3.75TSYY63 pKa = 11.66SLLVNFPQAFEE74 pKa = 4.13NAVYY78 pKa = 8.66TAQLIQTISGASSLIAAGIQTQPFQIFDD106 pKa = 3.71AGSNMALQQWRR117 pKa = 11.84PDD119 pKa = 3.58YY120 pKa = 10.97FDD122 pKa = 3.94VFIPGYY128 pKa = 9.98RR129 pKa = 11.84HH130 pKa = 5.73FEE132 pKa = 4.15YY133 pKa = 10.88YY134 pKa = 10.85FNVLSGWGEE143 pKa = 4.1SLVNTVSRR151 pKa = 11.84AFWEE155 pKa = 4.22ALLSEE160 pKa = 4.52TRR162 pKa = 11.84QTARR166 pKa = 11.84LLASNAVDD174 pKa = 3.06NVYY177 pKa = 11.03NVGEE181 pKa = 4.09QGLQNIQNALVGLIEE196 pKa = 4.09GARR199 pKa = 11.84WALRR203 pKa = 11.84FPGNVYY209 pKa = 10.63HH210 pKa = 6.52NLEE213 pKa = 4.07MYY215 pKa = 9.79YY216 pKa = 10.78AQLPGLTPPQVRR228 pKa = 11.84SIQKK232 pKa = 9.8RR233 pKa = 11.84LEE235 pKa = 3.7EE236 pKa = 4.01ARR238 pKa = 11.84NYY240 pKa = 9.78GPSVQVDD247 pKa = 3.45DD248 pKa = 4.83SEE250 pKa = 4.88NSVFSEE256 pKa = 4.46HH257 pKa = 7.16LSGDD261 pKa = 3.66YY262 pKa = 10.34IFRR265 pKa = 11.84GEE267 pKa = 4.13APGGARR273 pKa = 11.84QRR275 pKa = 11.84QTPDD279 pKa = 2.15WMLQLILGILGDD291 pKa = 3.39ITPFFKK297 pKa = 10.61EE298 pKa = 3.79VIEE301 pKa = 4.06EE302 pKa = 4.32VEE304 pKa = 4.14GEE306 pKa = 4.26EE307 pKa = 4.95NADD310 pKa = 3.36

Molecular weight: 34.18 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|I6ULL7|I6ULL7_9POLY Minor capsid protein VP2 OS=MW polyomavirus OX=1203539 GN=VP3 PE=3 SV=1
MM1 pKa = 7.79DD2 pKa = 4.63RR3 pKa = 11.84VLSRR7 pKa = 11.84DD8 pKa = 3.33EE9 pKa = 4.46VKK11 pKa = 10.96EE12 pKa = 3.79LMALLSLNVAAWGNIPLMQYY32 pKa = 10.52KK33 pKa = 9.65YY34 pKa = 10.65RR35 pKa = 11.84QACLKK40 pKa = 9.6LHH42 pKa = 6.86PDD44 pKa = 3.24KK45 pKa = 11.65GGDD48 pKa = 3.6GEE50 pKa = 4.46KK51 pKa = 9.62MKK53 pKa = 10.69RR54 pKa = 11.84LNEE57 pKa = 4.33LFSKK61 pKa = 10.09MYY63 pKa = 7.8TTIEE67 pKa = 3.79KK68 pKa = 10.13LRR70 pKa = 11.84RR71 pKa = 11.84EE72 pKa = 4.34GEE74 pKa = 4.26VYY76 pKa = 10.34FPAKK80 pKa = 9.68VGYY83 pKa = 9.81FIEE86 pKa = 4.88DD87 pKa = 3.71VVTLGDD93 pKa = 3.53VLGPTFEE100 pKa = 4.36EE101 pKa = 4.37KK102 pKa = 9.93IIYY105 pKa = 9.13IWPLCASDD113 pKa = 5.1LVRR116 pKa = 11.84HH117 pKa = 5.96KK118 pKa = 10.45CGCVCCLLKK127 pKa = 10.55KK128 pKa = 7.61QHH130 pKa = 6.77RR131 pKa = 11.84NDD133 pKa = 3.35KK134 pKa = 10.17LAKK137 pKa = 9.6QKK139 pKa = 10.56QCLVWGEE146 pKa = 4.31CFCYY150 pKa = 10.55SCFLLWFGQEE160 pKa = 3.73FGYY163 pKa = 9.63TSFFWWKK170 pKa = 10.33HH171 pKa = 3.34IMHH174 pKa = 7.09NIEE177 pKa = 4.23FDD179 pKa = 3.79LLRR182 pKa = 11.84LLGEE186 pKa = 4.68LILWVSVSFFILGG199 pKa = 3.34

Molecular weight: 23.38 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

0

5

1780

199

668

356.0

40.18

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.73 ± 0.901

2.697 ± 0.706

5.393 ± 0.556

6.798 ± 1.034

4.494 ± 0.679

6.629 ± 0.64

1.629 ± 0.253

5.112 ± 0.48

5.449 ± 1.472

10.169 ± 0.846

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.36 ± 0.274

4.944 ± 0.448

5.73 ± 1.171

4.494 ± 0.512

4.607 ± 0.292

5.787 ± 0.524

5.562 ± 1.324

7.022 ± 0.723

1.742 ± 0.331

3.652 ± 0.238
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski