Simian immunodeficiency virus (isolate MB66) (SIV-cpz) (Chimpanzee immunodeficiency virus)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Simian immunodeficiency virus; Simian immunodeficiency virus - cpz

Average proteome isoelectric point is 7.55

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 9 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q1A263|REV_SIVMB Protein Rev OS=Simian immunodeficiency virus (isolate MB66) OX=388911 GN=rev PE=3 SV=1
MM1 pKa = 8.23DD2 pKa = 4.26IVQQVGLLVVLIIEE16 pKa = 4.16LVIVIVIWVKK26 pKa = 10.28VYY28 pKa = 10.6KK29 pKa = 10.35LCKK32 pKa = 8.96EE33 pKa = 4.07DD34 pKa = 4.15RR35 pKa = 11.84RR36 pKa = 11.84QKK38 pKa = 10.91KK39 pKa = 9.05IDD41 pKa = 3.48RR42 pKa = 11.84LIARR46 pKa = 11.84IRR48 pKa = 11.84EE49 pKa = 3.94RR50 pKa = 11.84AEE52 pKa = 4.05DD53 pKa = 3.71SGNEE57 pKa = 3.97SDD59 pKa = 5.61GDD61 pKa = 3.95TEE63 pKa = 4.15EE64 pKa = 4.43LQDD67 pKa = 6.34LITEE71 pKa = 5.2GDD73 pKa = 3.6NLMHH77 pKa = 7.27IGIRR81 pKa = 11.84DD82 pKa = 3.43NRR84 pKa = 11.84NNN86 pKa = 3.32

Molecular weight: 9.98 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q1A264|TAT_SIVMB Protein Tat OS=Simian immunodeficiency virus (isolate MB66) OX=388911 GN=tat PE=3 SV=1
MM1 pKa = 7.75AGGSGNSDD9 pKa = 3.59EE10 pKa = 4.42EE11 pKa = 4.07LLRR14 pKa = 11.84AVRR17 pKa = 11.84IIKK20 pKa = 9.77ILYY23 pKa = 8.77QSNPYY28 pKa = 9.44PSPEE32 pKa = 3.82GSRR35 pKa = 11.84QARR38 pKa = 11.84RR39 pKa = 11.84NRR41 pKa = 11.84RR42 pKa = 11.84RR43 pKa = 11.84RR44 pKa = 11.84WRR46 pKa = 11.84ARR48 pKa = 11.84QRR50 pKa = 11.84QINSLSEE57 pKa = 4.76RR58 pKa = 11.84ILSTCLEE65 pKa = 4.45RR66 pKa = 11.84PTGPVSLPLPPIEE79 pKa = 5.58RR80 pKa = 11.84LTLDD84 pKa = 3.18SAEE87 pKa = 4.96DD88 pKa = 3.32IGTGGTDD95 pKa = 3.36PPQGTEE101 pKa = 3.85TGTGSPNTPEE111 pKa = 3.8GHH113 pKa = 5.28STILGTGAKK122 pKa = 9.41NN123 pKa = 3.1

Molecular weight: 13.34 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9

0

9

3623

86

1438

402.6

45.63

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.934 ± 0.555

2.098 ± 0.362

4.03 ± 0.196

7.287 ± 0.562

2.705 ± 0.3

7.452 ± 0.334

2.125 ± 0.421

6.707 ± 0.745

6.542 ± 0.843

8.556 ± 0.94

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.96 ± 0.227

4.913 ± 0.648

5.244 ± 0.763

6.017 ± 0.547

6.238 ± 0.754

4.83 ± 0.508

6.183 ± 0.61

6.128 ± 0.485

2.484 ± 0.219

2.567 ± 0.275
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski