Amino acid dipepetide frequency for Fusarium sporotrichioides

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.397AlaAla: 8.397 ± 0.057	1.056AlaCys: 1.056 ± 0.014	4.17AlaAsp: 4.17 ± 0.029	5.032AlaGlu: 5.032 ± 0.047	3.111AlaPhe: 3.111 ± 0.03	5.534AlaGly: 5.534 ± 0.041	1.671AlaHis: 1.671 ± 0.014	4.438AlaIle: 4.438 ± 0.033	4.217AlaLys: 4.217 ± 0.03	7.401AlaLeu: 7.401 ± 0.034	1.987AlaMet: 1.987 ± 0.018	2.959AlaAsn: 2.959 ± 0.026	4.724AlaPro: 4.724 ± 0.036	3.322AlaGln: 3.322 ± 0.028	4.465AlaArg: 4.465 ± 0.028	7.029AlaSer: 7.029 ± 0.041	5.236AlaThr: 5.236 ± 0.038	5.225AlaVal: 5.225 ± 0.037	1.166AlaTrp: 1.166 ± 0.017	2.135AlaTyr: 2.135 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.917CysAla: 0.917 ± 0.013	0.244CysCys: 0.244 ± 0.007	0.701CysAsp: 0.701 ± 0.013	0.612CysGlu: 0.612 ± 0.012	0.568CysPhe: 0.568 ± 0.01	0.94CysGly: 0.94 ± 0.015	0.328CysHis: 0.328 ± 0.008	0.738CysIle: 0.738 ± 0.012	0.548CysLys: 0.548 ± 0.01	1.23CysLeu: 1.23 ± 0.015	0.28CysMet: 0.28 ± 0.006	0.47CysAsn: 0.47 ± 0.009	0.652CysPro: 0.652 ± 0.014	0.482CysGln: 0.482 ± 0.01	0.719CysArg: 0.719 ± 0.014	0.891CysSer: 0.891 ± 0.013	0.721CysThr: 0.721 ± 0.013	0.821CysVal: 0.821 ± 0.015	0.219CysTrp: 0.219 ± 0.007	0.369CysTyr: 0.369 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.679AspAla: 4.679 ± 0.03	0.673AspCys: 0.673 ± 0.013	4.665AspAsp: 4.665 ± 0.041	4.684AspGlu: 4.684 ± 0.034	2.331AspPhe: 2.331 ± 0.024	4.114AspGly: 4.114 ± 0.03	1.271AspHis: 1.271 ± 0.02	3.304AspIle: 3.304 ± 0.026	2.802AspLys: 2.802 ± 0.024	5.093AspLeu: 5.093 ± 0.031	1.402AspMet: 1.402 ± 0.016	2.19AspAsn: 2.19 ± 0.022	3.325AspPro: 3.325 ± 0.027	2.019AspGln: 2.019 ± 0.019	2.985AspArg: 2.985 ± 0.03	4.289AspSer: 4.289 ± 0.032	3.175AspThr: 3.175 ± 0.028	3.784AspVal: 3.784 ± 0.024	0.945AspTrp: 0.945 ± 0.012	1.67AspTyr: 1.67 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.509GluAla: 5.509 ± 0.042	0.65GluCys: 0.65 ± 0.011	4.331GluAsp: 4.331 ± 0.037	5.425GluGlu: 5.425 ± 0.049	2.027GluPhe: 2.027 ± 0.017	3.661GluGly: 3.661 ± 0.027	1.409GluHis: 1.409 ± 0.018	3.096GluIle: 3.096 ± 0.023	3.826GluLys: 3.826 ± 0.031	5.121GluLeu: 5.121 ± 0.038	1.48GluMet: 1.48 ± 0.016	2.436GluAsn: 2.436 ± 0.022	3.015GluPro: 3.015 ± 0.035	2.502GluGln: 2.502 ± 0.02	3.71GluArg: 3.71 ± 0.029	4.425GluSer: 4.425 ± 0.032	3.838GluThr: 3.838 ± 0.037	3.582GluVal: 3.582 ± 0.029	0.923GluTrp: 0.923 ± 0.011	1.686GluTyr: 1.686 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.009PheAla: 3.009 ± 0.026	0.578PheCys: 0.578 ± 0.01	2.372PheAsp: 2.372 ± 0.02	2.221PheGlu: 2.221 ± 0.02	1.657PhePhe: 1.657 ± 0.02	2.919PheGly: 2.919 ± 0.028	0.904PheHis: 0.904 ± 0.012	1.946PheIle: 1.946 ± 0.02	1.67PheLys: 1.67 ± 0.017	3.408PheLeu: 3.408 ± 0.027	0.853PheMet: 0.853 ± 0.012	1.558PheAsn: 1.558 ± 0.016	1.892PhePro: 1.892 ± 0.018	1.429PheGln: 1.429 ± 0.015	1.86PheArg: 1.86 ± 0.02	2.995PheSer: 2.995 ± 0.024	2.216PheThr: 2.216 ± 0.019	2.442PheVal: 2.442 ± 0.023	0.677PheTrp: 0.677 ± 0.011	1.124PheTyr: 1.124 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.076GlyAla: 5.076 ± 0.038	0.887GlyCys: 0.887 ± 0.013	3.788GlyAsp: 3.788 ± 0.029	3.541GlyGlu: 3.541 ± 0.029	2.845GlyPhe: 2.845 ± 0.025	5.5GlyGly: 5.5 ± 0.051	1.656GlyHis: 1.656 ± 0.018	3.656GlyIle: 3.656 ± 0.031	3.492GlyLys: 3.492 ± 0.028	5.991GlyLeu: 5.991 ± 0.038	1.583GlyMet: 1.583 ± 0.019	2.731GlyAsn: 2.731 ± 0.027	3.269GlyPro: 3.269 ± 0.031	2.63GlyGln: 2.63 ± 0.023	3.912GlyArg: 3.912 ± 0.03	5.675GlySer: 5.675 ± 0.04	4.034GlyThr: 4.034 ± 0.041	4.257GlyVal: 4.257 ± 0.032	1.187GlyTrp: 1.187 ± 0.015	2.179GlyTyr: 2.179 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.721HisAla: 1.721 ± 0.016	0.325HisCys: 0.325 ± 0.008	1.427HisAsp: 1.427 ± 0.017	1.361HisGlu: 1.361 ± 0.015	0.905HisPhe: 0.905 ± 0.014	1.709HisGly: 1.709 ± 0.021	0.823HisHis: 0.823 ± 0.016	1.227HisIle: 1.227 ± 0.014	0.97HisLys: 0.97 ± 0.014	2.153HisLeu: 2.153 ± 0.019	0.519HisMet: 0.519 ± 0.008	0.88HisAsn: 0.88 ± 0.014	1.507HisPro: 1.507 ± 0.017	1.006HisGln: 1.006 ± 0.015	1.432HisArg: 1.432 ± 0.016	1.719HisSer: 1.719 ± 0.019	1.191HisThr: 1.191 ± 0.016	1.431HisVal: 1.431 ± 0.015	0.346HisTrp: 0.346 ± 0.007	0.703HisTyr: 0.703 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.28IleAla: 4.28 ± 0.027	0.774IleCys: 0.774 ± 0.011	3.039IleAsp: 3.039 ± 0.024	3.076IleGlu: 3.076 ± 0.027	2.053IlePhe: 2.053 ± 0.021	3.321IleGly: 3.321 ± 0.026	1.202IleHis: 1.202 ± 0.015	2.708IleIle: 2.708 ± 0.025	2.422IleLys: 2.422 ± 0.025	4.581IleLeu: 4.581 ± 0.031	1.109IleMet: 1.109 ± 0.016	1.971IleAsn: 1.971 ± 0.02	3.097IlePro: 3.097 ± 0.021	1.958IleGln: 1.958 ± 0.018	2.757IleArg: 2.757 ± 0.022	3.933IleSer: 3.933 ± 0.03	3.023IleThr: 3.023 ± 0.033	3.344IleVal: 3.344 ± 0.029	0.79IleTrp: 0.79 ± 0.013	1.447IleTyr: 1.447 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.398LysAla: 4.398 ± 0.036	0.535LysCys: 0.535 ± 0.012	3.163LysAsp: 3.163 ± 0.026	3.495LysGlu: 3.495 ± 0.03	1.564LysPhe: 1.564 ± 0.016	3.111LysGly: 3.111 ± 0.024	1.188LysHis: 1.188 ± 0.015	2.383LysIle: 2.383 ± 0.019	3.563LysLys: 3.563 ± 0.041	4.197LysLeu: 4.197 ± 0.031	1.082LysMet: 1.082 ± 0.014	1.96LysAsn: 1.96 ± 0.021	2.973LysPro: 2.973 ± 0.027	1.957LysGln: 1.957 ± 0.02	3.293LysArg: 3.293 ± 0.028	3.719LysSer: 3.719 ± 0.031	3.151LysThr: 3.151 ± 0.028	2.995LysVal: 2.995 ± 0.026	0.728LysTrp: 0.728 ± 0.01	1.453LysTyr: 1.453 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	7.477LeuAla: 7.477 ± 0.04	1.191LeuCys: 1.191 ± 0.016	5.184LeuAsp: 5.184 ± 0.034	5.462LeuGlu: 5.462 ± 0.039	3.277LeuPhe: 3.277 ± 0.025	5.775LeuGly: 5.775 ± 0.038	2.064LeuHis: 2.064 ± 0.022	4.052LeuIle: 4.052 ± 0.03	4.262LeuLys: 4.262 ± 0.031	7.845LeuLeu: 7.845 ± 0.049	1.831LeuMet: 1.831 ± 0.017	3.223LeuAsn: 3.223 ± 0.023	5.213LeuPro: 5.213 ± 0.039	3.65LeuGln: 3.65 ± 0.026	5.288LeuArg: 5.288 ± 0.039	7.058LeuSer: 7.058 ± 0.041	4.755LeuThr: 4.755 ± 0.032	5.413LeuVal: 5.413 ± 0.04	1.209LeuTrp: 1.209 ± 0.018	2.337LeuTyr: 2.337 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.274MetAla: 2.274 ± 0.02	0.256MetCys: 0.256 ± 0.006	1.305MetAsp: 1.305 ± 0.015	1.302MetGlu: 1.302 ± 0.015	0.793MetPhe: 0.793 ± 0.012	1.521MetGly: 1.521 ± 0.017	0.489MetHis: 0.489 ± 0.01	1.078MetIle: 1.078 ± 0.013	1.076MetLys: 1.076 ± 0.014	1.835MetLeu: 1.835 ± 0.018	0.638MetMet: 0.638 ± 0.011	0.85MetAsn: 0.85 ± 0.011	1.34MetPro: 1.34 ± 0.017	0.843MetGln: 0.843 ± 0.014	1.232MetArg: 1.232 ± 0.015	2.008MetSer: 2.008 ± 0.019	1.395MetThr: 1.395 ± 0.016	1.334MetVal: 1.334 ± 0.014	0.277MetTrp: 0.277 ± 0.007	0.555MetTyr: 0.555 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.13AsnAla: 3.13 ± 0.024	0.473AsnCys: 0.473 ± 0.011	2.246AsnAsp: 2.246 ± 0.021	2.173AsnGlu: 2.173 ± 0.018	1.451AsnPhe: 1.451 ± 0.016	3.108AsnGly: 3.108 ± 0.029	0.888AsnHis: 0.888 ± 0.015	2.152AsnIle: 2.152 ± 0.019	1.839AsnLys: 1.839 ± 0.018	3.343AsnLeu: 3.343 ± 0.021	0.944AsnMet: 0.944 ± 0.012	1.689AsnAsn: 1.689 ± 0.022	2.435AsnPro: 2.435 ± 0.022	1.423AsnGln: 1.423 ± 0.019	1.965AsnArg: 1.965 ± 0.019	2.911AsnSer: 2.911 ± 0.022	2.325AsnThr: 2.325 ± 0.019	2.368AsnVal: 2.368 ± 0.022	0.6AsnTrp: 0.6 ± 0.01	1.117AsnTyr: 1.117 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	4.935ProAla: 4.935 ± 0.041	0.528ProCys: 0.528 ± 0.009	3.315ProAsp: 3.315 ± 0.024	4.052ProGlu: 4.052 ± 0.032	2.061ProPhe: 2.061 ± 0.021	3.931ProGly: 3.931 ± 0.048	1.247ProHis: 1.247 ± 0.015	2.58ProIle: 2.58 ± 0.023	2.877ProLys: 2.877 ± 0.024	4.463ProLeu: 4.463 ± 0.028	1.131ProMet: 1.131 ± 0.013	2.218ProAsn: 2.218 ± 0.02	4.687ProPro: 4.687 ± 0.056	2.488ProGln: 2.488 ± 0.031	3.178ProArg: 3.178 ± 0.03	5.66ProSer: 5.66 ± 0.048	3.963ProThr: 3.963 ± 0.032	3.626ProVal: 3.626 ± 0.03	0.768ProTrp: 0.768 ± 0.013	1.514ProTyr: 1.514 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.446GlnAla: 3.446 ± 0.027	0.444GlnCys: 0.444 ± 0.01	2.326GlnAsp: 2.326 ± 0.021	2.51GlnGlu: 2.51 ± 0.02	1.3GlnPhe: 1.3 ± 0.015	2.524GlnGly: 2.524 ± 0.022	1.065GlnHis: 1.065 ± 0.015	1.9GlnIle: 1.9 ± 0.018	2.007GlnLys: 2.007 ± 0.022	3.317GlnLeu: 3.317 ± 0.028	0.899GlnMet: 0.899 ± 0.014	1.632GlnAsn: 1.632 ± 0.019	2.572GlnPro: 2.572 ± 0.033	2.448GlnGln: 2.448 ± 0.058	2.482GlnArg: 2.482 ± 0.021	3.085GlnSer: 3.085 ± 0.029	2.341GlnThr: 2.341 ± 0.022	2.283GlnVal: 2.283 ± 0.021	0.588GlnTrp: 0.588 ± 0.01	1.164GlnTyr: 1.164 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	4.239ArgAla: 4.239 ± 0.032	0.672ArgCys: 0.672 ± 0.012	3.394ArgAsp: 3.394 ± 0.03	3.566ArgGlu: 3.566 ± 0.03	2.094ArgPhe: 2.094 ± 0.02	3.49ArgGly: 3.49 ± 0.027	1.484ArgHis: 1.484 ± 0.017	2.832ArgIle: 2.832 ± 0.024	3.272ArgLys: 3.272 ± 0.025	5.095ArgLeu: 5.095 ± 0.032	1.278ArgMet: 1.278 ± 0.014	2.257ArgAsn: 2.257 ± 0.023	3.337ArgPro: 3.337 ± 0.03	2.526ArgGln: 2.526 ± 0.022	4.667ArgArg: 4.667 ± 0.043	4.47ArgSer: 4.47 ± 0.036	3.118ArgThr: 3.118 ± 0.024	3.199ArgVal: 3.199 ± 0.024	0.908ArgTrp: 0.908 ± 0.014	1.64ArgTyr: 1.64 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.21SerAla: 6.21 ± 0.037	0.89SerCys: 0.89 ± 0.013	4.438SerAsp: 4.438 ± 0.035	4.296SerGlu: 4.296 ± 0.03	3.132SerPhe: 3.132 ± 0.03	5.479SerGly: 5.479 ± 0.04	1.908SerHis: 1.908 ± 0.02	4.154SerIle: 4.154 ± 0.026	3.959SerLys: 3.959 ± 0.034	6.96SerLeu: 6.96 ± 0.043	1.769SerMet: 1.769 ± 0.017	3.133SerAsn: 3.133 ± 0.024	5.21SerPro: 5.21 ± 0.045	3.331SerGln: 3.331 ± 0.029	4.749SerArg: 4.749 ± 0.038	8.248SerSer: 8.248 ± 0.061	5.484SerThr: 5.484 ± 0.04	4.62SerVal: 4.62 ± 0.03	1.19SerTrp: 1.19 ± 0.015	2.13SerTyr: 2.13 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.119ThrAla: 5.119 ± 0.04	0.785ThrCys: 0.785 ± 0.013	3.039ThrAsp: 3.039 ± 0.023	3.427ThrGlu: 3.427 ± 0.033	2.273ThrPhe: 2.273 ± 0.02	4.202ThrGly: 4.202 ± 0.04	1.254ThrHis: 1.254 ± 0.012	3.333ThrIle: 3.333 ± 0.034	2.931ThrLys: 2.931 ± 0.024	5.13ThrLeu: 5.13 ± 0.032	1.241ThrMet: 1.241 ± 0.014	2.259ThrAsn: 2.259 ± 0.02	4.241ThrPro: 4.241 ± 0.038	2.218ThrGln: 2.218 ± 0.021	3.083ThrArg: 3.083 ± 0.025	5.321ThrSer: 5.321 ± 0.041	4.597ThrThr: 4.597 ± 0.069	3.878ThrVal: 3.878 ± 0.047	0.918ThrTrp: 0.918 ± 0.013	1.667ThrTyr: 1.667 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	5.199ValAla: 5.199 ± 0.032	0.852ValCys: 0.852 ± 0.016	3.813ValAsp: 3.813 ± 0.024	3.935ValGlu: 3.935 ± 0.025	2.493ValPhe: 2.493 ± 0.024	3.968ValGly: 3.968 ± 0.036	1.362ValHis: 1.362 ± 0.015	3.09ValIle: 3.09 ± 0.027	3.071ValLys: 3.071 ± 0.027	5.423ValLeu: 5.423 ± 0.035	1.342ValMet: 1.342 ± 0.013	2.301ValAsn: 2.301 ± 0.018	3.618ValPro: 3.618 ± 0.024	2.351ValGln: 2.351 ± 0.02	3.255ValArg: 3.255 ± 0.025	4.704ValSer: 4.704 ± 0.032	3.728ValThr: 3.728 ± 0.041	4.333ValVal: 4.333 ± 0.03	0.897ValTrp: 0.897 ± 0.013	1.739ValTyr: 1.739 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.161TrpAla: 1.161 ± 0.015	0.206TrpCys: 0.206 ± 0.006	0.956TrpAsp: 0.956 ± 0.013	0.882TrpGlu: 0.882 ± 0.012	0.585TrpPhe: 0.585 ± 0.01	0.97TrpGly: 0.97 ± 0.014	0.368TrpHis: 0.368 ± 0.008	0.819TrpIle: 0.819 ± 0.013	0.862TrpLys: 0.862 ± 0.013	1.39TrpLeu: 1.39 ± 0.017	0.384TrpMet: 0.384 ± 0.008	0.672TrpAsn: 0.672 ± 0.011	0.639TrpPro: 0.639 ± 0.01	0.603TrpGln: 0.603 ± 0.009	0.905TrpArg: 0.905 ± 0.013	1.097TrpSer: 1.097 ± 0.014	0.959TrpThr: 0.959 ± 0.012	0.906TrpVal: 0.906 ± 0.013	0.294TrpTrp: 0.294 ± 0.008	0.453TrpTyr: 0.453 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.1TyrAla: 2.1 ± 0.019	0.429TyrCys: 0.429 ± 0.009	1.731TyrAsp: 1.731 ± 0.02	1.6TyrGlu: 1.6 ± 0.018	1.211TyrPhe: 1.211 ± 0.016	2.111TyrGly: 2.111 ± 0.024	0.775TyrHis: 0.775 ± 0.012	1.398TyrIle: 1.398 ± 0.016	1.241TyrLys: 1.241 ± 0.018	2.589TyrLeu: 2.589 ± 0.024	0.651TyrMet: 0.651 ± 0.01	1.192TyrAsn: 1.192 ± 0.016	1.472TyrPro: 1.472 ± 0.021	1.143TyrGln: 1.143 ± 0.014	1.599TyrArg: 1.599 ± 0.018	2.052TyrSer: 2.052 ± 0.02	1.668TyrThr: 1.668 ± 0.02	1.638TyrVal: 1.638 ± 0.018	0.483TyrTrp: 0.483 ± 0.01	0.951TyrTyr: 0.951 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11960 proteins (6079613 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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