Simian immunodeficiency virus (isolate CPZ GAB1) (SIV-cpz) (Chimpanzee immunodeficiency virus)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Simian immunodeficiency virus; Simian immunodeficiency virus - cpz

Average proteome isoelectric point is 7.62

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 9 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P17664|NEF_SIVCZ Protein Nef OS=Simian immunodeficiency virus (isolate CPZ GAB1) OX=402771 GN=nef PE=3 SV=3
MM1 pKa = 6.24GTKK4 pKa = 8.93WSKK7 pKa = 10.74SSLVGWPEE15 pKa = 3.24VRR17 pKa = 11.84RR18 pKa = 11.84RR19 pKa = 11.84IRR21 pKa = 11.84EE22 pKa = 3.91APTAAEE28 pKa = 4.39GVGEE32 pKa = 4.05VSKK35 pKa = 11.08DD36 pKa = 3.72LEE38 pKa = 3.98RR39 pKa = 11.84HH40 pKa = 4.8GAITSRR46 pKa = 11.84NTPEE50 pKa = 4.05TNQTLAWLEE59 pKa = 3.87EE60 pKa = 3.98MDD62 pKa = 3.87NEE64 pKa = 4.29EE65 pKa = 3.55VGFPVRR71 pKa = 11.84PQVPTRR77 pKa = 11.84PMTYY81 pKa = 9.89KK82 pKa = 10.62AAFDD86 pKa = 3.95LSHH89 pKa = 6.79FLKK92 pKa = 10.76EE93 pKa = 4.12KK94 pKa = 10.73GGLEE98 pKa = 3.75GLVYY102 pKa = 10.33SRR104 pKa = 11.84RR105 pKa = 11.84RR106 pKa = 11.84QEE108 pKa = 5.63ILDD111 pKa = 3.24LWVYY115 pKa = 8.03HH116 pKa = 5.36TQGFFPDD123 pKa = 3.35WQNYY127 pKa = 4.89TTGPGTRR134 pKa = 11.84FPLCFGWCFKK144 pKa = 10.56LVPLTEE150 pKa = 4.3EE151 pKa = 3.88QVEE154 pKa = 4.27QANEE158 pKa = 3.88GDD160 pKa = 4.34NNCLLHH166 pKa = 6.67PICQHH171 pKa = 5.66GMEE174 pKa = 5.29DD175 pKa = 3.5EE176 pKa = 4.48DD177 pKa = 5.66KK178 pKa = 11.04EE179 pKa = 4.48VLVWRR184 pKa = 11.84FDD186 pKa = 3.14SRR188 pKa = 11.84LALRR192 pKa = 11.84HH193 pKa = 5.68IARR196 pKa = 11.84EE197 pKa = 3.91QHH199 pKa = 5.58PEE201 pKa = 3.94YY202 pKa = 11.15YY203 pKa = 10.33KK204 pKa = 10.91DD205 pKa = 3.25

Molecular weight: 23.85 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P17285|TAT_SIVCZ Protein Tat OS=Simian immunodeficiency virus (isolate CPZ GAB1) OX=402771 GN=tat PE=3 SV=1
MM1 pKa = 7.3EE2 pKa = 5.21NRR4 pKa = 11.84WQVMIVWQVDD14 pKa = 3.01RR15 pKa = 11.84MRR17 pKa = 11.84IKK19 pKa = 9.27TWNSLVKK26 pKa = 8.92YY27 pKa = 10.13HH28 pKa = 7.56IYY30 pKa = 9.99RR31 pKa = 11.84SKK33 pKa = 10.72KK34 pKa = 8.49ARR36 pKa = 11.84GWFYY40 pKa = 10.41RR41 pKa = 11.84HH42 pKa = 6.71HH43 pKa = 7.12YY44 pKa = 9.52DD45 pKa = 3.87HH46 pKa = 7.8PNPKK50 pKa = 9.36VASEE54 pKa = 3.35IHH56 pKa = 6.27IPFRR60 pKa = 11.84DD61 pKa = 3.73YY62 pKa = 11.66SKK64 pKa = 11.26LIVTTYY70 pKa = 8.9WALSPGEE77 pKa = 4.22RR78 pKa = 11.84AWHH81 pKa = 6.31LGHH84 pKa = 6.6GVSIQWRR91 pKa = 11.84LGSYY95 pKa = 7.48VTQVDD100 pKa = 4.19PFTADD105 pKa = 3.5RR106 pKa = 11.84LIHH109 pKa = 6.05SQYY112 pKa = 10.35FDD114 pKa = 4.16CFAEE118 pKa = 4.27TAIRR122 pKa = 11.84RR123 pKa = 11.84AILGQLVAPRR133 pKa = 11.84CEE135 pKa = 4.1YY136 pKa = 10.98KK137 pKa = 10.34EE138 pKa = 3.78GHH140 pKa = 5.91RR141 pKa = 11.84QVGSLQFLALKK152 pKa = 10.6ALISEE157 pKa = 4.38RR158 pKa = 11.84RR159 pKa = 11.84HH160 pKa = 5.72RR161 pKa = 11.84PPLPSVAKK169 pKa = 9.23LTEE172 pKa = 4.24DD173 pKa = 2.93RR174 pKa = 11.84WNKK177 pKa = 8.12HH178 pKa = 4.28QRR180 pKa = 11.84TKK182 pKa = 10.4VHH184 pKa = 5.98QEE186 pKa = 3.1NLTRR190 pKa = 11.84NGHH193 pKa = 5.22

Molecular weight: 23.05 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9

0

9

3552

88

1384

394.7

44.62

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.363 ± 0.377

2.083 ± 0.342

4.026 ± 0.252

6.813 ± 0.771

2.59 ± 0.214

7.686 ± 0.494

2.421 ± 0.505

6.194 ± 0.804

6.56 ± 0.847

8.418 ± 0.686

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.802 ± 0.196

4.505 ± 0.653

5.377 ± 0.519

6.025 ± 0.465

6.363 ± 0.836

5.377 ± 0.592

5.743 ± 0.514

6.334 ± 0.479

2.703 ± 0.214

2.618 ± 0.282
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski