Proteome-pI 2.0 - Proteome Isoelectric Point Database

Shahe endorna-like virus 1

Taxonomy: Viruses; Riboviria; unclassified Riboviria; unclassified RNA viruses ShiM-2016

Average proteome isoelectric point is 5.94

Get precalculated fractions of proteins

Acidic

pI < 6.8

6.8-7.4

pI > 7.4

Basic

All

Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

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* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions

Protein with the lowest isoelectric point:

>tr|A0A1L3KK54|A0A1L3KK54_9VIRU RdRp catalytic domain-containing protein OS=Shahe endorna-like virus 1 OX=1923414 PE=4 SV=1

MM1 pKa = 7.36MLLNMYY7 pKa = 9.91GATTPLEE14 pKa = 3.94GRR16 pKa = 11.84IDD18 pKa = 3.79LQYY21 pKa = 11.25LNPKK25 pKa = 9.86IIGKK29 pKa = 8.82IVWMYY34 pKa = 11.08KK35 pKa = 9.9NNEE38 pKa = 4.24LFTDD42 pKa = 4.24LTDD45 pKa = 4.08DD46 pKa = 4.69QYY48 pKa = 12.07NNWKK52 pKa = 9.7VRR54 pKa = 11.84VRR56 pKa = 11.84HH57 pKa = 6.07NYY59 pKa = 8.65LAPLRR64 pKa = 11.84DD65 pKa = 3.51YY66 pKa = 11.09EE67 pKa = 4.98DD68 pKa = 4.28RR69 pKa = 11.84YY70 pKa = 10.79LYY72 pKa = 10.63HH73 pKa = 8.1LGIDD77 pKa = 4.06PQTVTAPSPKK87 pKa = 9.67PSGARR92 pKa = 11.84LMEE95 pKa = 4.15KK96 pKa = 10.35LAIEE100 pKa = 4.01MRR102 pKa = 11.84KK103 pKa = 8.93FATATQRR110 pKa = 11.84VKK112 pKa = 10.95HH113 pKa = 5.23GVEE116 pKa = 3.88RR117 pKa = 11.84HH118 pKa = 5.97NGWEE122 pKa = 4.02QYY124 pKa = 10.58ILACATARR132 pKa = 11.84PDD134 pKa = 4.75AMGQALNIRR143 pKa = 11.84GRR145 pKa = 11.84MDD147 pKa = 3.46TNPCVAPVMVCGVCSAPNLMSHH169 pKa = 6.9HH170 pKa = 7.5DD171 pKa = 4.12SPCVYY176 pKa = 10.42LPQSWVKK183 pKa = 10.76DD184 pKa = 3.56YY185 pKa = 11.53AKK187 pKa = 10.34QHH189 pKa = 6.28LLPEE193 pKa = 4.38NTWDD197 pKa = 4.56DD198 pKa = 4.4SEE200 pKa = 4.33LHH202 pKa = 6.69NYY204 pKa = 9.62DD205 pKa = 3.52LQTPVHH211 pKa = 5.79TPVIRR216 pKa = 11.84STKK219 pKa = 9.61QKK221 pKa = 9.56LTVTEE226 pKa = 4.23EE227 pKa = 4.24EE228 pKa = 4.19EE229 pKa = 4.48VAWRR233 pKa = 11.84CGACFADD240 pKa = 5.3LGILVIDD247 pKa = 3.18QWITFDD253 pKa = 5.66LVLQAISDD261 pKa = 4.16PDD263 pKa = 4.03PPVMGLLEE271 pKa = 4.14YY272 pKa = 10.38LKK274 pKa = 10.9LMRR277 pKa = 11.84YY278 pKa = 10.02GDD280 pKa = 4.72FIDD283 pKa = 5.45EE284 pKa = 4.09ISKK287 pKa = 10.52QEE289 pKa = 4.01GEE291 pKa = 4.59TIMKK295 pKa = 9.62HH296 pKa = 6.03DD297 pKa = 3.45RR298 pKa = 11.84TIVKK302 pKa = 10.0RR303 pKa = 11.84ALRR306 pKa = 11.84DD307 pKa = 3.3ASTKK311 pKa = 10.62LITVGPDD318 pKa = 3.04VPPEE322 pKa = 4.09LFTEE326 pKa = 4.48LNRR329 pKa = 11.84LYY331 pKa = 9.78VKK333 pKa = 10.64CVARR337 pKa = 11.84PLACKK342 pKa = 9.92TSMSPQLATEE352 pKa = 4.41LAYY355 pKa = 10.58ADD357 pKa = 3.64SWVSAKK363 pKa = 10.67LNSTDD368 pKa = 3.33QLLKK372 pKa = 10.41IGSLSWEE379 pKa = 3.86YY380 pKa = 10.88RR381 pKa = 11.84PGNHH385 pKa = 6.2HH386 pKa = 6.65HH387 pKa = 6.79WNYY390 pKa = 10.8NPILMGQYY398 pKa = 9.54IGEE401 pKa = 4.36GLCFTTGPCEE411 pKa = 4.32HH412 pKa = 7.38KK413 pKa = 10.24LHH415 pKa = 6.65CPAVFGMGALNDD427 pKa = 3.81TLTNFMSAVKK437 pKa = 9.71NQSDD441 pKa = 4.25AYY443 pKa = 10.83LILLNPGQKK452 pKa = 10.61LLGPLTSNLGYY463 pKa = 10.36IKK465 pKa = 10.74DD466 pKa = 3.64NGEE469 pKa = 3.94CLEE472 pKa = 4.24IYY474 pKa = 10.03IDD476 pKa = 3.54GTMYY480 pKa = 10.52PLVVNKK486 pKa = 9.81EE487 pKa = 4.07LYY489 pKa = 9.88EE490 pKa = 3.95VLINSDD496 pKa = 4.57AIVDD500 pKa = 4.06GNDD503 pKa = 3.46CYY505 pKa = 11.81SLLTVKK511 pKa = 10.54KK512 pKa = 10.45GIDD515 pKa = 3.51VVIKK519 pKa = 10.61HH520 pKa = 5.95IMGPVNQEE528 pKa = 4.25SIGKK532 pKa = 8.58LVNVSTPTKK541 pKa = 9.7KK542 pKa = 10.43KK543 pKa = 10.1IVMPVPDD550 pKa = 3.84TTGVMGLWTALAYY563 pKa = 9.74KK564 pKa = 10.28DD565 pKa = 4.86LEE567 pKa = 4.23IDD569 pKa = 4.19FEE571 pKa = 5.57PGLFRR576 pKa = 11.84EE577 pKa = 4.2LCIRR581 pKa = 11.84NFTGKK586 pKa = 10.22CGRR589 pKa = 11.84DD590 pKa = 3.19DD591 pKa = 3.92LMSYY595 pKa = 10.64GMGYY599 pKa = 10.9ALTRR603 pKa = 11.84FTVHH607 pKa = 5.35NTVIHH612 pKa = 6.12NPQVCASQIQIHH624 pKa = 5.83VFLCQVTMGVANSRR638 pKa = 11.84AAINNQALTLLSKK651 pKa = 10.94LGPLKK656 pKa = 10.94SIVTGHH662 pKa = 7.17LEE664 pKa = 4.07SLDD667 pKa = 3.55DD668 pKa = 4.5AVRR671 pKa = 11.84TGIKK675 pKa = 8.99WLAEE679 pKa = 4.32SKK681 pKa = 10.69FSLDD685 pKa = 4.13FEE687 pKa = 5.69NIMNTLTEE695 pKa = 4.02VQINEE700 pKa = 4.18WVSGITKK707 pKa = 6.71THH709 pKa = 5.15IWEE712 pKa = 4.59DD713 pKa = 3.27LLDD716 pKa = 4.02IVNSYY721 pKa = 10.32PVGDD725 pKa = 3.93VKK727 pKa = 10.95VHH729 pKa = 5.29VMHH732 pKa = 6.87KK733 pKa = 9.94PSALRR738 pKa = 11.84TLPSHH743 pKa = 6.84RR744 pKa = 11.84CHH746 pKa = 5.81HH747 pKa = 6.49HH748 pKa = 6.04SWGCDD753 pKa = 2.79HH754 pKa = 6.97TSINTSEE761 pKa = 4.48LCEE764 pKa = 4.28CCGMPTPEE772 pKa = 4.62EE773 pKa = 5.22GYY775 pKa = 10.38CICCMPKK782 pKa = 9.62PDD784 pKa = 4.89LEE786 pKa = 4.64HH787 pKa = 7.32EE788 pKa = 4.25YY789 pKa = 11.16GIDD792 pKa = 3.39LFNVVDD798 pKa = 3.96PKK800 pKa = 11.42SRR802 pKa = 11.84VKK804 pKa = 10.44EE805 pKa = 3.91VSDD808 pKa = 4.32VITKK812 pKa = 7.82EE813 pKa = 4.32VKK815 pKa = 9.15TSRR818 pKa = 11.84VDD820 pKa = 3.25KK821 pKa = 11.05SNSEE825 pKa = 4.09SLMAAFIKK833 pKa = 10.3QISRR837 pKa = 11.84IGLKK841 pKa = 10.67DD842 pKa = 3.46RR843 pKa = 11.84DD844 pKa = 4.24EE845 pKa = 4.44KK846 pKa = 11.34EE847 pKa = 3.62KK848 pKa = 10.49TPRR851 pKa = 11.84IDD853 pKa = 3.3LSKK856 pKa = 9.83TPRR859 pKa = 11.84LTAVNSTQAKK869 pKa = 6.22STKK872 pKa = 10.08RR873 pKa = 11.84KK874 pKa = 9.66GKK876 pKa = 7.68TAAKK880 pKa = 9.8PDD882 pKa = 3.78EE883 pKa = 4.45TDD885 pKa = 3.71LRR887 pKa = 11.84PSSTTPAPPTADD899 pKa = 3.23VLDD902 pKa = 4.63EE903 pKa = 4.31VPGTQVCDD911 pKa = 3.52ATDD914 pKa = 3.34VTNNAGEE921 pKa = 4.21FVTDD925 pKa = 3.84DD926 pKa = 4.33VEE928 pKa = 4.43GQSIDD933 pKa = 3.61QEE935 pKa = 4.09EE936 pKa = 4.88LEE938 pKa = 4.36RR939 pKa = 11.84KK940 pKa = 9.05IAVAEE945 pKa = 3.97EE946 pKa = 4.01LKK948 pKa = 10.59RR949 pKa = 11.84LYY951 pKa = 10.38RR952 pKa = 11.84SRR954 pKa = 11.84THH956 pKa = 5.4NHH958 pKa = 4.41QEE960 pKa = 3.91KK961 pKa = 10.3VAATHH966 pKa = 5.14LTEE969 pKa = 4.88NKK971 pKa = 9.96VNTLNPSYY979 pKa = 10.88DD980 pKa = 3.35YY981 pKa = 11.6SDD983 pKa = 3.62YY984 pKa = 11.26FNLLGAEE991 pKa = 4.32FATYY995 pKa = 10.91LLDD998 pKa = 4.76RR999 pKa = 11.84EE1000 pKa = 4.26QSLIDD1005 pKa = 3.68LQAAKK1010 pKa = 9.25TKK1012 pKa = 8.99PYY1014 pKa = 10.49EE1015 pKa = 4.02VIIPYY1020 pKa = 9.98VPIGIHH1026 pKa = 5.14NHH1028 pKa = 4.34TDD1030 pKa = 2.31QWMEE1034 pKa = 3.64VLSRR1038 pKa = 11.84INVSNTYY1045 pKa = 10.84DD1046 pKa = 3.48NSCGLDD1052 pKa = 2.9AYY1054 pKa = 11.23NYY1056 pKa = 7.04VTGRR1060 pKa = 11.84GLSRR1064 pKa = 11.84EE1065 pKa = 4.33EE1066 pKa = 3.72ILSLIGVDD1074 pKa = 4.07NNLLTTDD1081 pKa = 4.71LANLADD1087 pKa = 3.77ACGDD1091 pKa = 3.54NLILITEE1098 pKa = 4.69LSVITCKK1105 pKa = 10.69YY1106 pKa = 9.84SEE1108 pKa = 4.24SDD1110 pKa = 3.63VFPVIVLDD1118 pKa = 3.78STSPDD1123 pKa = 3.27NGHH1126 pKa = 6.34YY1127 pKa = 10.65SPAIVLLRR1135 pKa = 11.84NDD1137 pKa = 3.66PGFYY1141 pKa = 10.28AIRR1144 pKa = 11.84AGPSLEE1150 pKa = 4.03SFRR1153 pKa = 11.84TDD1155 pKa = 2.56ILTLKK1160 pKa = 10.41GLNQGCLFGRR1170 pKa = 11.84TPITAQDD1177 pKa = 3.57NLIIEE1182 pKa = 4.92LTTKK1186 pKa = 10.14QCSDD1190 pKa = 3.96DD1191 pKa = 4.08LDD1193 pKa = 3.82NAVISIRR1200 pKa = 11.84TPEE1203 pKa = 3.68VRR1205 pKa = 11.84RR1206 pKa = 11.84IGDD1209 pKa = 3.73GYY1211 pKa = 11.36YY1212 pKa = 8.77FTNSPGGIHH1221 pKa = 6.89KK1222 pKa = 9.87PGHH1225 pKa = 5.92HH1226 pKa = 7.14LYY1228 pKa = 10.2HH1229 pKa = 6.51KK1230 pKa = 9.69PIRR1233 pKa = 11.84EE1234 pKa = 4.18SILNVIEE1241 pKa = 4.6AMSTTEE1247 pKa = 3.96PNMALKK1253 pKa = 10.81SNLLNTIFNRR1263 pKa = 11.84EE1264 pKa = 3.52PRR1266 pKa = 11.84IADD1269 pKa = 3.51NLVQEE1274 pKa = 4.53YY1275 pKa = 9.85DD1276 pKa = 3.57HH1277 pKa = 6.89KK1278 pKa = 11.38VRR1280 pKa = 11.84EE1281 pKa = 4.34AVKK1284 pKa = 10.63SVIDD1288 pKa = 3.85LQVAFGDD1295 pKa = 3.42GRR1297 pKa = 11.84MPSKK1301 pKa = 10.39VKK1303 pKa = 9.7SWHH1306 pKa = 5.86KK1307 pKa = 10.5VEE1309 pKa = 5.26CKK1311 pKa = 10.62ASGKK1315 pKa = 5.8WTSIINPCPKK1325 pKa = 10.29LKK1327 pKa = 9.94TLDD1330 pKa = 3.03WVYY1333 pKa = 9.81ITNKK1337 pKa = 9.33SGSYY1341 pKa = 9.68LRR1343 pKa = 11.84QVVIDD1348 pKa = 3.66RR1349 pKa = 11.84TRR1351 pKa = 11.84LLVASLGRR1359 pKa = 11.84QCDD1362 pKa = 3.75GSKK1365 pKa = 10.68LGVLDD1370 pKa = 3.86TSVASAIKK1378 pKa = 10.44CIATYY1383 pKa = 10.53CSTVPDD1389 pKa = 3.8GKK1391 pKa = 10.65KK1392 pKa = 9.66IRR1394 pKa = 11.84EE1395 pKa = 4.19LLANAIVIDD1404 pKa = 4.46GVAGHH1409 pKa = 6.68GKK1411 pKa = 10.17SNAIAQEE1418 pKa = 4.55CNTSDD1423 pKa = 3.6LVIAKK1428 pKa = 7.61THH1430 pKa = 6.1LAVAGLRR1437 pKa = 11.84AKK1439 pKa = 8.77ITKK1442 pKa = 9.51RR1443 pKa = 11.84VNVLSIEE1450 pKa = 4.28RR1451 pKa = 11.84AVGDD1455 pKa = 4.03PPHH1458 pKa = 7.18HH1459 pKa = 5.46YY1460 pKa = 9.43TRR1462 pKa = 11.84IIIDD1466 pKa = 3.66EE1467 pKa = 4.47ASMVDD1472 pKa = 3.81YY1473 pKa = 11.18IEE1475 pKa = 4.26ICPLISAEE1483 pKa = 4.08VTEE1486 pKa = 4.5LKK1488 pKa = 10.73LYY1490 pKa = 10.75GDD1492 pKa = 4.0SRR1494 pKa = 11.84QIGNRR1499 pKa = 11.84DD1500 pKa = 3.36FSSSGGVRR1508 pKa = 11.84HH1509 pKa = 5.92TLNLMDD1515 pKa = 4.99LAGSAHH1521 pKa = 5.55VSKK1524 pKa = 10.69EE1525 pKa = 3.87NQSYY1529 pKa = 10.63RR1530 pKa = 11.84IGYY1533 pKa = 7.2PAAEE1537 pKa = 4.47YY1538 pKa = 10.24VQQLYY1543 pKa = 10.63PEE1545 pKa = 4.3FTGTTEE1551 pKa = 4.22HH1552 pKa = 6.08NTGFQIVHH1560 pKa = 5.81VNPDD1564 pKa = 3.33NVEE1567 pKa = 3.98KK1568 pKa = 10.96LRR1570 pKa = 11.84DD1571 pKa = 4.7DD1572 pKa = 3.25ILMAKK1577 pKa = 9.55FDD1579 pKa = 4.04VVITFYY1585 pKa = 11.47NHH1587 pKa = 4.9TKK1589 pKa = 10.22ILLEE1593 pKa = 3.96KK1594 pKa = 9.99LLPKK1598 pKa = 9.92EE1599 pKa = 4.29VPVVTAHH1606 pKa = 6.88SYY1608 pKa = 9.58QGRR1611 pKa = 11.84EE1612 pKa = 4.05ANRR1615 pKa = 11.84VAVVQWPDD1623 pKa = 2.9ANGNMTLCRR1632 pKa = 11.84HH1633 pKa = 5.21MNYY1636 pKa = 9.44MYY1638 pKa = 10.11TAVTRR1643 pKa = 11.84GISQTTLYY1651 pKa = 10.54TSLNVDD1657 pKa = 4.39DD1658 pKa = 5.6NPSLSQLVTMGGQGHH1673 pKa = 6.13TRR1675 pKa = 11.84YY1676 pKa = 9.52QPPTTTDD1683 pKa = 2.71KK1684 pKa = 11.38YY1685 pKa = 10.47LTRR1688 pKa = 11.84LDD1690 pKa = 4.51KK1691 pKa = 10.75ISLRR1695 pKa = 11.84NSHH1698 pKa = 6.22LWEE1701 pKa = 5.61DD1702 pKa = 4.33DD1703 pKa = 4.45LIQALQGNKK1712 pKa = 10.34DD1713 pKa = 3.49KK1714 pKa = 10.95DD1715 pKa = 3.94GKK1717 pKa = 10.91SITVKK1722 pKa = 9.94RR1723 pKa = 11.84TDD1725 pKa = 2.99TATIISVMDD1734 pKa = 4.12GKK1736 pKa = 10.43NKK1738 pKa = 10.24KK1739 pKa = 9.32IGYY1742 pKa = 8.22FVNEE1746 pKa = 4.45GGNLTANFGFGLANMVAMSKK1766 pKa = 10.48VDD1768 pKa = 3.79DD1769 pKa = 4.28LVVDD1773 pKa = 4.18VKK1775 pKa = 11.37DD1776 pKa = 3.45GGVYY1780 pKa = 10.39NRR1782 pKa = 11.84DD1783 pKa = 3.61TKK1785 pKa = 9.28THH1787 pKa = 6.1IAGPLAKK1794 pKa = 10.38DD1795 pKa = 3.37KK1796 pKa = 11.33TNLEE1800 pKa = 4.04HH1801 pKa = 7.42LYY1803 pKa = 10.2VEE1805 pKa = 4.37EE1806 pKa = 3.54MLYY1809 pKa = 10.11PVEE1812 pKa = 5.18HH1813 pKa = 6.9RR1814 pKa = 11.84PPLNKK1819 pKa = 9.84IMDD1822 pKa = 4.02HH1823 pKa = 5.06VACPNSMWKK1832 pKa = 8.1TVLVPTVQQMCKK1844 pKa = 9.47IRR1846 pKa = 11.84MATYY1850 pKa = 9.3MCDD1853 pKa = 3.33CSLPNHH1859 pKa = 6.94SITYY1863 pKa = 5.64TTPDD1867 pKa = 3.4GPITMSKK1874 pKa = 9.29TEE1876 pKa = 4.21GCPLACGLKK1885 pKa = 10.5LEE1887 pKa = 4.75FKK1889 pKa = 10.7GSVVNISSQYY1899 pKa = 8.45RR1900 pKa = 11.84NWWTRR1905 pKa = 11.84SISVTGRR1912 pKa = 11.84WGQNGRR1918 pKa = 11.84QLLTAVGKK1926 pKa = 9.02WLGVKK1931 pKa = 9.66IPKK1934 pKa = 10.17DD1935 pKa = 3.38LTDD1938 pKa = 3.69NCHH1941 pKa = 6.0EE1942 pKa = 4.41LSIPVYY1948 pKa = 9.69PSTAISARR1956 pKa = 11.84LYY1958 pKa = 10.48AEE1960 pKa = 4.29RR1961 pKa = 11.84MSHH1964 pKa = 7.17GIFGIANLLNMHH1976 pKa = 6.94KK1977 pKa = 9.44VTADD1981 pKa = 3.57CADD1984 pKa = 3.77GEE1986 pKa = 4.51AVQTAEE1992 pKa = 5.28RR1993 pKa = 11.84ITSHH1997 pKa = 6.28YY1998 pKa = 9.38KK1999 pKa = 9.95LHH2001 pKa = 6.56SGNIKK2006 pKa = 9.68VRR2008 pKa = 11.84SPHH2011 pKa = 5.42KK2012 pKa = 8.95TWLVHH2017 pKa = 5.18HH2018 pKa = 7.14KK2019 pKa = 10.25KK2020 pKa = 10.54RR2021 pKa = 11.84GWIRR2025 pKa = 11.84NYY2027 pKa = 10.7DD2028 pKa = 3.86VISIGPACRR2037 pKa = 11.84PWIEE2041 pKa = 4.0RR2042 pKa = 11.84QSISVEE2048 pKa = 3.7LMSYY2052 pKa = 9.47LVEE2055 pKa = 4.51MIEE2058 pKa = 4.31KK2059 pKa = 10.15DD2060 pKa = 3.36LAGKK2064 pKa = 8.65VEE2066 pKa = 4.28KK2067 pKa = 10.6PEE2069 pKa = 3.88FDD2071 pKa = 3.25AVGSFDD2077 pKa = 4.6LEE2079 pKa = 4.44GMILDD2084 pKa = 3.92VNYY2087 pKa = 10.36HH2088 pKa = 5.45ITNDD2092 pKa = 3.37TSVGKK2097 pKa = 8.98EE2098 pKa = 3.83LKK2100 pKa = 10.27RR2101 pKa = 11.84SAGHH2105 pKa = 6.18ISQYY2109 pKa = 7.69TTVKK2113 pKa = 10.04PKK2115 pKa = 8.95EE2116 pKa = 3.88HH2117 pKa = 6.24LVISEE2122 pKa = 3.74VGMRR2126 pKa = 11.84EE2127 pKa = 3.89LRR2129 pKa = 11.84SEE2131 pKa = 4.29LKK2133 pKa = 10.63DD2134 pKa = 3.55AFPLMHH2140 pKa = 6.57VNPHH2144 pKa = 4.55SHH2146 pKa = 7.31AISGSYY2152 pKa = 10.12VEE2154 pKa = 4.81EE2155 pKa = 4.69CLDD2158 pKa = 3.5SLAINIVGEE2167 pKa = 4.25TFEE2170 pKa = 4.5TCDD2173 pKa = 3.31LSYY2176 pKa = 10.6VGKK2179 pKa = 9.12MPHH2182 pKa = 6.26IPYY2185 pKa = 10.03VLNKK2189 pKa = 9.99HH2190 pKa = 4.67YY2191 pKa = 11.23VKK2193 pKa = 10.94LITPASHH2200 pKa = 5.11YY2201 pKa = 7.24THH2203 pKa = 5.85YY2204 pKa = 10.95HH2205 pKa = 5.07EE2206 pKa = 4.35WHH2208 pKa = 6.73EE2209 pKa = 4.3SLNLAKK2215 pKa = 9.57TLHH2218 pKa = 5.93HH2219 pKa = 6.83NYY2221 pKa = 9.48RR2222 pKa = 11.84EE2223 pKa = 4.14AMHH2226 pKa = 6.92ASEE2229 pKa = 5.35PDD2231 pKa = 3.34MTVKK2235 pKa = 10.48PFGTIQPPDD2244 pKa = 3.42SGTIIVAGTSLHH2256 pKa = 6.95AIPYY2260 pKa = 8.89HH2261 pKa = 6.89DD2262 pKa = 4.45LRR2264 pKa = 11.84SWMAEE2269 pKa = 3.8GKK2271 pKa = 10.06RR2272 pKa = 11.84VFGWVPDD2279 pKa = 3.74FTNGSEE2285 pKa = 4.36RR2286 pKa = 11.84FYY2288 pKa = 10.82TPEE2291 pKa = 3.84KK2292 pKa = 9.9TSTGANITYY2301 pKa = 10.25HH2302 pKa = 6.88LGHH2305 pKa = 6.88KK2306 pKa = 10.03PSAVDD2311 pKa = 3.53RR2312 pKa = 11.84KK2313 pKa = 10.19LLEE2316 pKa = 4.14MCNMGRR2322 pKa = 11.84PIIQDD2327 pKa = 3.44NEE2329 pKa = 3.63PSIICRR2335 pKa = 11.84HH2336 pKa = 5.41IKK2338 pKa = 10.27SVLGHH2343 pKa = 6.57KK2344 pKa = 9.89LVEE2347 pKa = 4.71VILSTKK2353 pKa = 9.63EE2354 pKa = 3.67RR2355 pKa = 11.84FNVQLEE2361 pKa = 4.38SMVMSGTKK2369 pKa = 10.47VNVDD2373 pKa = 3.76LPFINLDD2380 pKa = 3.55PVQLLSGGPVVQVKK2394 pKa = 10.15RR2395 pKa = 11.84YY2396 pKa = 6.67TICKK2400 pKa = 9.57KK2401 pKa = 10.38LLRR2404 pKa = 11.84LLQLRR2409 pKa = 11.84MAQPGCKK2416 pKa = 7.84TTDD2419 pKa = 3.23VLSYY2423 pKa = 10.96ARR2425 pKa = 11.84SLASACEE2432 pKa = 3.78ITDD2435 pKa = 3.19RR2436 pKa = 11.84SIRR2439 pKa = 11.84YY2440 pKa = 6.06THH2442 pKa = 7.34DD2443 pKa = 3.23VDD2445 pKa = 5.73LKK2447 pKa = 10.09CLHH2450 pKa = 6.11HH2451 pKa = 5.95TAYY2454 pKa = 10.66LAVYY2458 pKa = 8.85LQGHH2462 pKa = 5.1MKK2464 pKa = 9.89EE2465 pKa = 4.17RR2466 pKa = 11.84YY2467 pKa = 8.13HH2468 pKa = 6.28WLSSVWDD2475 pKa = 4.1LLRR2478 pKa = 11.84KK2479 pKa = 9.85NDD2481 pKa = 4.6GIAANAQVILGGFAKK2496 pKa = 9.73ICSMFSDD2503 pKa = 3.85AVSEE2507 pKa = 3.97FLQPEE2512 pKa = 4.58LLNTILNNKK2521 pKa = 9.06KK2522 pKa = 10.52LGITNAEE2529 pKa = 4.35LKK2531 pKa = 10.49RR2532 pKa = 11.84LEE2534 pKa = 4.8GEE2536 pKa = 4.27LQAKK2540 pKa = 9.12LNWQNRR2546 pKa = 11.84YY2547 pKa = 6.13WVQYY2551 pKa = 8.03TNHH2554 pKa = 6.17HH2555 pKa = 5.81VSRR2558 pKa = 11.84NPSTTQTNHH2567 pKa = 5.4GLEE2570 pKa = 4.37SEE2572 pKa = 5.05DD2573 pKa = 5.31GGEE2576 pKa = 3.87DD2577 pKa = 2.5WWNNEE2582 pKa = 3.49RR2583 pKa = 11.84DD2584 pKa = 3.78DD2585 pKa = 5.2NYY2587 pKa = 9.91FTTVAEE2593 pKa = 4.56DD2594 pKa = 3.65DD2595 pKa = 3.85EE2596 pKa = 5.59LYY2598 pKa = 11.01NLQSHH2603 pKa = 5.67TQVEE2607 pKa = 5.02SKK2609 pKa = 10.7LHH2611 pKa = 4.26GHH2613 pKa = 6.09INKK2616 pKa = 9.31EE2617 pKa = 3.96LLVNSPNQYY2626 pKa = 11.01AKK2628 pKa = 9.49EE2629 pKa = 4.17TVPTATCEE2637 pKa = 3.96FGKK2640 pKa = 9.53QHH2642 pKa = 5.95QPVIDD2647 pKa = 3.88SCVEE2651 pKa = 3.78LTTQNQLVDD2660 pKa = 4.63LGQSPSIEE2668 pKa = 3.67IVVRR2672 pKa = 11.84EE2673 pKa = 4.29LGSPRR2678 pKa = 11.84AVMEE2682 pKa = 4.55SYY2684 pKa = 11.05GQIQTDD2690 pKa = 3.77TCSPPTKK2697 pKa = 10.25LRR2699 pKa = 11.84TEE2701 pKa = 4.29VAVKK2705 pKa = 10.15SQQLEE2710 pKa = 4.08PGVQTRR2716 pKa = 11.84SDD2718 pKa = 3.65TTPNDD2723 pKa = 3.13IPYY2726 pKa = 9.51KK2727 pKa = 10.27PPGGHH2732 pKa = 6.43DD2733 pKa = 3.78TIPPQNTSPSNQKK2746 pKa = 10.14LKK2748 pKa = 11.06SGTTEE2753 pKa = 3.79LTEE2756 pKa = 4.57NPPNMDD2762 pKa = 3.11GTKK2765 pKa = 10.21EE2766 pKa = 3.96IFDD2769 pKa = 4.77DD2770 pKa = 4.25ADD2772 pKa = 3.42EE2773 pKa = 4.3FHH2775 pKa = 7.27DD2776 pKa = 4.26AKK2778 pKa = 11.05EE2779 pKa = 4.53SISDD2783 pKa = 3.58LDD2785 pKa = 3.77SRR2787 pKa = 11.84YY2788 pKa = 10.32EE2789 pKa = 3.97DD2790 pKa = 3.44YY2791 pKa = 11.03LYY2793 pKa = 11.57NLLGEE2798 pKa = 4.69SNTEE2802 pKa = 3.54EE2803 pKa = 4.26RR2804 pKa = 11.84QDD2806 pKa = 3.46LKK2808 pKa = 11.4NRR2810 pKa = 11.84FWFDD2814 pKa = 2.77KK2815 pKa = 10.41KK2816 pKa = 10.78LRR2818 pKa = 11.84GYY2820 pKa = 10.26FISQEE2825 pKa = 3.98RR2826 pKa = 11.84LNQYY2830 pKa = 8.56STDD2833 pKa = 3.72PDD2835 pKa = 3.48QQAEE2839 pKa = 4.06LSGFIDD2845 pKa = 3.79KK2846 pKa = 11.13GLDD2849 pKa = 3.43LSRR2852 pKa = 11.84SDD2854 pKa = 5.59AGDD2857 pKa = 3.21QVDD2860 pKa = 4.77RR2861 pKa = 11.84YY2862 pKa = 10.83AVITTSLFEE2871 pKa = 4.93DD2872 pKa = 4.18PGVLPTDD2879 pKa = 3.89STHH2882 pKa = 6.7DD2883 pKa = 3.7TQSSSVEE2890 pKa = 4.08STQEE2894 pKa = 3.55LVTALEE2900 pKa = 4.22EE2901 pKa = 4.56SPADD2905 pKa = 3.34TCIPSRR2911 pKa = 11.84PDD2913 pKa = 4.14DD2914 pKa = 3.59INIQIVEE2921 pKa = 4.22PAATPHH2927 pKa = 7.15ADD2929 pKa = 3.51PCEE2932 pKa = 4.2LSPKK2936 pKa = 10.21LDD2938 pKa = 4.03TPPSTQSVEE2947 pKa = 4.22VGLSSQDD2954 pKa = 3.15TMTHH2958 pKa = 6.15EE2959 pKa = 4.38EE2960 pKa = 4.42TLTSLTNTIDD2970 pKa = 3.38TTNQSDD2976 pKa = 3.82DD2977 pKa = 3.26TGTPFKK2983 pKa = 10.24TRR2985 pKa = 11.84LSMIPIPRR2993 pKa = 11.84KK2994 pKa = 9.93KK2995 pKa = 10.02PPTHH2999 pKa = 5.9STPTRR3004 pKa = 11.84PWDD3007 pKa = 3.28RR3008 pKa = 11.84TTQTEE3013 pKa = 4.34PGPTPHH3019 pKa = 5.5VQNRR3023 pKa = 11.84KK3024 pKa = 7.04TPSPVSSKK3032 pKa = 10.54HH3033 pKa = 4.79MKK3035 pKa = 9.81YY3036 pKa = 10.8DD3037 pKa = 3.42HH3038 pKa = 7.45LDD3040 pKa = 3.71TNFHH3044 pKa = 5.99GAEE3047 pKa = 3.88ISHH3050 pKa = 7.05ASNLQNMIRR3059 pKa = 11.84DD3060 pKa = 3.65IDD3062 pKa = 3.72RR3063 pKa = 11.84LSIMEE3068 pKa = 4.07VSDD3071 pKa = 3.43TTEE3074 pKa = 3.8SGTPPAHH3081 pKa = 7.54DD3082 pKa = 5.83DD3083 pKa = 3.2IAKK3086 pKa = 10.36EE3087 pKa = 4.33SIEE3090 pKa = 4.12HH3091 pKa = 6.13ATDD3094 pKa = 3.66QEE3096 pKa = 4.81YY3097 pKa = 11.16VWLISVGSSGDD3108 pKa = 3.39IVAMDD3113 pKa = 4.39PVAEE3117 pKa = 4.31SLMPDD3122 pKa = 3.53YY3123 pKa = 10.78KK3124 pKa = 11.15VVVATHH3130 pKa = 6.87FDD3132 pKa = 3.46LMHH3135 pKa = 6.63CVPEE3139 pKa = 4.41GQGKK3143 pKa = 9.69VMLPISSKK3151 pKa = 10.06VVMKK3155 pKa = 10.79AVVDD3159 pKa = 3.85NLTKK3163 pKa = 10.85GMIHH3167 pKa = 6.31MFSTGPKK3174 pKa = 8.39TIKK3177 pKa = 10.6LMAEE3181 pKa = 4.06VIEE3184 pKa = 4.15PLFNIKK3190 pKa = 10.31PNVSLIVSNHH3200 pKa = 4.3FTPLVGLLAAHH3211 pKa = 7.27WGCKK3215 pKa = 8.83LVHH3218 pKa = 7.01AYY3220 pKa = 10.27AFDD3223 pKa = 4.84PDD3225 pKa = 4.47CVDD3228 pKa = 4.84SFALHH3233 pKa = 6.25PKK3235 pKa = 9.62INSAPMVKK3243 pKa = 10.36EE3244 pKa = 3.57MINPIKK3250 pKa = 10.28ATILRR3255 pKa = 11.84ALDD3258 pKa = 3.65FSMANQLNINCPNPIDD3274 pKa = 3.61IAATPKK3280 pKa = 10.71LITSSEE3286 pKa = 3.87LMASDD3291 pKa = 3.99EE3292 pKa = 4.56STNKK3296 pKa = 8.92WGKK3299 pKa = 10.56LYY3301 pKa = 10.34IGSTARR3307 pKa = 11.84TGCVAGNSAEE3317 pKa = 4.09TMKK3320 pKa = 10.62FVSTGSITLITWGSVYY3336 pKa = 10.62SEE3338 pKa = 4.37YY3339 pKa = 10.76NQSILQDD3346 pKa = 3.8LVVHH3350 pKa = 6.79TINSGSKK3357 pKa = 10.23VLFNNYY3363 pKa = 8.87KK3364 pKa = 10.32KK3365 pKa = 10.75LYY3367 pKa = 8.93TLDD3370 pKa = 3.23KK3371 pKa = 10.23VKK3373 pKa = 10.78VVTLCKK3379 pKa = 10.09PNSCAMDD3386 pKa = 3.54RR3387 pKa = 11.84LLIVEE3392 pKa = 4.31SLDD3395 pKa = 3.59YY3396 pKa = 11.35NLVLPRR3402 pKa = 11.84CKK3404 pKa = 10.4AIVHH3408 pKa = 6.37HH3409 pKa = 6.65GGSGTTHH3416 pKa = 5.84QAVSYY3421 pKa = 9.32DD3422 pKa = 3.94VPSLILPIFGDD3433 pKa = 3.64QFWWSKK3439 pKa = 10.04RR3440 pKa = 11.84VNDD3443 pKa = 3.63LRR3445 pKa = 11.84IGIGLEE3451 pKa = 3.89AEE3453 pKa = 4.34SPITVVNKK3461 pKa = 10.37AVTRR3465 pKa = 11.84LLTRR3469 pKa = 11.84NQDD3472 pKa = 3.1YY3473 pKa = 10.44RR3474 pKa = 11.84KK3475 pKa = 10.31AIISSKK3481 pKa = 11.0LNLLFNRR3488 pKa = 11.84EE3489 pKa = 3.99MCRR3492 pKa = 11.84HH3493 pKa = 6.04LLLSYY3498 pKa = 9.92MAGQAIIEE3506 pKa = 4.47SPDD3509 pKa = 3.3TAFPEE3514 pKa = 4.37VPMRR3518 pKa = 11.84FANQVEE3524 pKa = 4.46MLQQLWGNSAGLSVIPVGVDD3544 pKa = 2.92KK3545 pKa = 11.19FFGSYY3550 pKa = 7.35EE3551 pKa = 4.08TEE3553 pKa = 3.64TWEE3556 pKa = 4.57GSISDD3561 pKa = 2.94IHH3563 pKa = 6.54YY3564 pKa = 9.87KK3565 pKa = 10.5RR3566 pKa = 11.84KK3567 pKa = 9.43FSKK3570 pKa = 10.1SRR3572 pKa = 11.84PRR3574 pKa = 11.84VLVCGWGTSGEE3585 pKa = 4.4FNVGMTYY3592 pKa = 10.62CKK3594 pKa = 10.28ALKK3597 pKa = 10.14EE3598 pKa = 4.07LGLVPILLTNCDD3610 pKa = 3.33QVSRR3614 pKa = 11.84IPEE3617 pKa = 3.9WVEE3620 pKa = 3.55YY3621 pKa = 10.16SCVPITSRR3629 pKa = 11.84VCTVLQLEE3637 pKa = 4.48SLRR3640 pKa = 11.84LDD3642 pKa = 3.5TMDD3645 pKa = 3.66NKK3647 pKa = 11.41AMVDD3651 pKa = 3.47QLKK3654 pKa = 9.6TYY3656 pKa = 10.34AAYY3659 pKa = 10.42DD3660 pKa = 3.97LLHH3663 pKa = 6.44SRR3665 pKa = 11.84PIKK3668 pKa = 10.34LIAVIGQEE3676 pKa = 3.96WFHH3679 pKa = 5.91TASIIAKK3686 pKa = 9.52AYY3688 pKa = 7.42NARR3691 pKa = 11.84MLYY3694 pKa = 10.44LSPHH3698 pKa = 7.13PYY3700 pKa = 9.81NLKK3703 pKa = 10.46NSPRR3707 pKa = 11.84PNGKK3711 pKa = 9.27PIDD3714 pKa = 4.19SKK3716 pKa = 11.03IHH3718 pKa = 5.46NASMAPGGKK3727 pKa = 8.06WKK3729 pKa = 10.63LYY3731 pKa = 9.59FGPGKK3736 pKa = 10.25ALEE3739 pKa = 4.32RR3740 pKa = 11.84MGFDD3744 pKa = 3.52PNLCVLEE3751 pKa = 4.8CEE3753 pKa = 4.62PSDD3756 pKa = 3.44TDD3758 pKa = 4.62VIISMHH3764 pKa = 6.89PDD3766 pKa = 3.88FVAGLVKK3773 pKa = 10.23EE3774 pKa = 4.34DD3775 pKa = 3.48EE3776 pKa = 4.34PRR3778 pKa = 11.84RR3779 pKa = 11.84HH3780 pKa = 5.19YY3781 pKa = 10.62VGHH3784 pKa = 6.85IGSTTWPDD3792 pKa = 3.34NEE3794 pKa = 4.91DD3795 pKa = 3.41PSLSKK3800 pKa = 10.85FILSNRR3806 pKa = 11.84NNICLVTASSCGSEE3820 pKa = 3.97STLNPFLTAIMYY3832 pKa = 8.2LVNNAHH3838 pKa = 5.83YY3839 pKa = 10.06VVVSGSFIKK3848 pKa = 9.72TLHH3851 pKa = 6.27PKK3853 pKa = 9.81SIKK3856 pKa = 10.5VGGKK3860 pKa = 7.86MVEE3863 pKa = 4.29LKK3865 pKa = 10.49PGQCHH3870 pKa = 5.31KK3871 pKa = 10.93QVFCTPALDD3880 pKa = 3.7LPRR3883 pKa = 11.84WAGYY3887 pKa = 10.4LYY3889 pKa = 10.82LAVHH3893 pKa = 6.73HH3894 pKa = 6.81GGTGTMLEE3902 pKa = 4.54CIRR3905 pKa = 11.84GKK3907 pKa = 10.02VPCLSWPIAFDD3918 pKa = 3.18QYY3920 pKa = 11.55LNARR3924 pKa = 11.84MTEE3927 pKa = 4.0YY3928 pKa = 10.62HH3929 pKa = 6.18QLTVGPCTPEE3939 pKa = 3.65EE3940 pKa = 4.06QEE3942 pKa = 4.98RR3943 pKa = 11.84GIQVYY3948 pKa = 10.66LDD3950 pKa = 3.15EE3951 pKa = 4.96LLRR3954 pKa = 11.84KK3955 pKa = 9.47RR3956 pKa = 11.84RR3957 pKa = 11.84AIKK3960 pKa = 9.77MNLEE3964 pKa = 4.08GMHH3967 pKa = 6.47HH3968 pKa = 6.78VGRR3971 pKa = 11.84CNSAVLTEE3979 pKa = 4.28TLAGLLNVFRR3989 pKa = 11.84NQPMWTHH3996 pKa = 6.42HH3997 pKa = 6.49SGHH4000 pKa = 6.72DD4001 pKa = 3.36VGVGLRR4007 pKa = 11.84GGAVMLPIGNFIDD4020 pKa = 4.15LASGVYY4026 pKa = 7.88TVKK4029 pKa = 11.02LEE4031 pKa = 4.38LEE4033 pKa = 4.48TEE4035 pKa = 4.22YY4036 pKa = 11.03SPPGIGYY4043 pKa = 7.47CTWNCYY4049 pKa = 7.46NRR4051 pKa = 11.84YY4052 pKa = 7.16MQNVCCNWEE4061 pKa = 4.11LLEE4064 pKa = 4.22PRR4066 pKa = 11.84YY4067 pKa = 10.16SDD4069 pKa = 3.82EE4070 pKa = 3.88YY4071 pKa = 10.86RR4072 pKa = 11.84KK4073 pKa = 9.9QSLSTVEE4080 pKa = 4.19VIKK4083 pKa = 11.08LGVQLGINVILSDD4096 pKa = 3.96INSKK4100 pKa = 9.06TSIYY4104 pKa = 10.63YY4105 pKa = 10.35HH4106 pKa = 7.0LFPGNNTIHH4115 pKa = 7.06LGLEE4119 pKa = 3.91NQTLMKK4125 pKa = 10.37HH4126 pKa = 6.3CILLKK4131 pKa = 10.81VPIEE4135 pKa = 4.05PPEE4138 pKa = 4.23LGSRR4142 pKa = 11.84VEE4144 pKa = 4.89LSQQKK4149 pKa = 9.34EE4150 pKa = 4.43NNWNIAITGLIEE4162 pKa = 3.95TGKK4165 pKa = 9.69IRR4167 pKa = 11.84CSRR4170 pKa = 11.84EE4171 pKa = 3.72QVNSAMEE4178 pKa = 4.24CVRR4181 pKa = 11.84DD4182 pKa = 4.2DD4183 pKa = 3.95MEE4185 pKa = 6.42ACFTDD4190 pKa = 3.69SNNLITRR4197 pKa = 11.84AALIQLHH4204 pKa = 6.99HH4205 pKa = 7.74IMEE4208 pKa = 4.37VQKK4211 pKa = 11.3NPILVDD4217 pKa = 3.67DD4218 pKa = 5.19FAFSTDD4224 pKa = 3.3GSASCAGRR4232 pKa = 11.84YY4233 pKa = 7.19SQWHH4237 pKa = 4.96NTLVLSPCIGGWGVGVCLYY4256 pKa = 10.8HH4257 pKa = 7.28SGRR4260 pKa = 11.84LTIKK4264 pKa = 10.65LFDD4267 pKa = 3.65GHH4269 pKa = 7.92IMTSGVALSLRR4280 pKa = 11.84ASCFKK4285 pKa = 10.69LYY4287 pKa = 9.79EE4288 pKa = 4.17ARR4290 pKa = 11.84CQVTITQQGEE4300 pKa = 3.94LLLALNQQTMKK4311 pKa = 10.0YY4312 pKa = 5.54TTSEE4316 pKa = 4.32VNCVKK4321 pKa = 10.46PSRR4324 pKa = 11.84VVGAQDD4330 pKa = 3.87DD4331 pKa = 4.49DD4332 pKa = 4.57YY4333 pKa = 11.78SLVIRR4338 pKa = 11.84HH4339 pKa = 5.45YY4340 pKa = 11.19DD4341 pKa = 3.25NRR4343 pKa = 11.84KK4344 pKa = 7.48HH4345 pKa = 6.27HH4346 pKa = 7.01LYY4348 pKa = 10.88DD4349 pKa = 3.37EE4350 pKa = 4.45ASYY4353 pKa = 10.77IEE4355 pKa = 4.31RR4356 pKa = 11.84AVSVRR4361 pKa = 11.84WLGEE4365 pKa = 4.17PINEE4369 pKa = 4.37TKK4371 pKa = 10.49FCDD4374 pKa = 3.22MTRR4377 pKa = 11.84SHH4379 pKa = 6.2NRR4381 pKa = 11.84AVDD4384 pKa = 3.52RR4385 pKa = 11.84VIYY4388 pKa = 10.48DD4389 pKa = 3.31HH4390 pKa = 6.82GQLLRR4395 pKa = 11.84CMEE4398 pKa = 4.38SSNKK4402 pKa = 9.09FWLLAAAGALVEE4414 pKa = 4.87RR4415 pKa = 11.84GQSYY4419 pKa = 10.64KK4420 pKa = 10.35IVGTSIVYY4428 pKa = 8.95RR4429 pKa = 11.84CKK4431 pKa = 10.44FRR4433 pKa = 11.84EE4434 pKa = 4.11SNIFDD4439 pKa = 3.5VMKK4442 pKa = 10.41KK4443 pKa = 7.69YY4444 pKa = 9.32TYY4446 pKa = 10.8NWLDD4450 pKa = 3.42EE4451 pKa = 4.55DD4452 pKa = 4.99ASDD4455 pKa = 4.7NKK4457 pKa = 10.36IATPLKK4463 pKa = 9.89WDD4465 pKa = 3.48VRR4467 pKa = 11.84WPLKK4471 pKa = 10.79NSDD4474 pKa = 3.37VASIFFIDD4482 pKa = 5.56LPTATAWITYY4492 pKa = 7.25LTGGRR4497 pKa = 11.84ADD4499 pKa = 3.59EE4500 pKa = 4.26VRR4502 pKa = 11.84LAEE4505 pKa = 5.01AIITTPVPACEE4516 pKa = 4.39IRR4518 pKa = 11.84TADD4521 pKa = 5.77DD4522 pKa = 3.45RR4523 pKa = 11.84DD4524 pKa = 3.55GWLLTHH4530 pKa = 7.24AAGSPALLTLRR4541 pKa = 11.84YY4542 pKa = 9.72GCYY4545 pKa = 9.79LVEE4548 pKa = 4.6AMAGGDD4554 pKa = 3.73TTGGSYY4560 pKa = 10.36SGAVWQEE4567 pKa = 3.81MKK4569 pKa = 10.71SNKK4572 pKa = 9.14HH4573 pKa = 5.34VSGDD4577 pKa = 3.07WFHH4580 pKa = 7.17IKK4582 pKa = 9.38PANEE4586 pKa = 3.99ADD4588 pKa = 3.65PKK4590 pKa = 10.0HH4591 pKa = 6.54RR4592 pKa = 11.84KK4593 pKa = 8.22AARR4596 pKa = 11.84EE4597 pKa = 3.94VAKK4600 pKa = 9.5LTTAMMMLEE4609 pKa = 4.15IEE4611 pKa = 4.4SLEE4614 pKa = 4.46HH4615 pKa = 5.65YY4616 pKa = 6.56TTTSISGVYY4625 pKa = 9.08EE4626 pKa = 3.95PEE4628 pKa = 3.71YY4629 pKa = 10.64LKK4631 pKa = 10.98YY4632 pKa = 10.05IEE4634 pKa = 4.83PMHH4637 pKa = 7.18DD4638 pKa = 2.72IGFLSEE4644 pKa = 4.78LEE4646 pKa = 4.14PLADD4650 pKa = 3.74YY4651 pKa = 9.61TPLHH4655 pKa = 6.02VLKK4658 pKa = 10.74LWDD4661 pKa = 4.04IEE4663 pKa = 4.34NDD4665 pKa = 3.37LTDD4668 pKa = 3.36WLQIYY4673 pKa = 10.04APQNVGSFITKK4684 pKa = 8.87EE4685 pKa = 3.73KK4686 pKa = 8.52PQRR4689 pKa = 11.84LIEE4692 pKa = 4.22CQKK4695 pKa = 8.16TTLTRR4700 pKa = 11.84YY4701 pKa = 8.86PLLSRR4706 pKa = 11.84PVLTKK4711 pKa = 10.51VAFEE4715 pKa = 4.13EE4716 pKa = 4.43TRR4718 pKa = 11.84TVAGRR4723 pKa = 11.84MFSIQHH4729 pKa = 5.31IRR4731 pKa = 11.84KK4732 pKa = 8.32GTIPTAKK4739 pKa = 8.92MVNDD4743 pKa = 3.55ICRR4746 pKa = 11.84AYY4748 pKa = 10.31FRR4750 pKa = 11.84PDD4752 pKa = 2.81WQEE4755 pKa = 3.5LCNKK4759 pKa = 9.39FKK4761 pKa = 10.86ADD4763 pKa = 4.3PIVYY4767 pKa = 10.01DD4768 pKa = 3.87PASIEE4773 pKa = 3.75NWIMEE4778 pKa = 4.35RR4779 pKa = 11.84KK4780 pKa = 8.89GAPEE4784 pKa = 4.06IIKK4787 pKa = 10.54EE4788 pKa = 4.3LMTKK4792 pKa = 10.55LAGEE4796 pKa = 4.76LMTKK4800 pKa = 10.13PISDD4804 pKa = 3.79VNIHH4808 pKa = 6.62LKK4810 pKa = 10.82LEE4812 pKa = 4.32SLLKK4816 pKa = 10.32EE4817 pKa = 4.18SPIVSWKK4824 pKa = 8.62QQQSRR4829 pKa = 11.84PIVWQPKK4836 pKa = 8.74AIAAIFSAVFIKK4848 pKa = 10.85AKK4850 pKa = 10.56DD4851 pKa = 3.5RR4852 pKa = 11.84LKK4854 pKa = 10.97EE4855 pKa = 3.86LLSDD4859 pKa = 3.48KK4860 pKa = 10.71VVYY4863 pKa = 10.83ADD4865 pKa = 3.21GHH4867 pKa = 5.79TPASLSARR4875 pKa = 11.84VRR4877 pKa = 11.84NVKK4880 pKa = 7.85GTKK4883 pKa = 8.28WFYY4886 pKa = 11.41EE4887 pKa = 3.9NDD4889 pKa = 3.17LTKK4892 pKa = 10.18QDD4894 pKa = 3.52RR4895 pKa = 11.84QTDD4898 pKa = 3.8EE4899 pKa = 5.33EE4900 pKa = 4.17ILKK4903 pKa = 10.53VEE4905 pKa = 3.83MAMYY4909 pKa = 9.91EE4910 pKa = 4.04LLGVHH4915 pKa = 6.76PLVISAWYY4923 pKa = 9.3SVHH4926 pKa = 6.26RR4927 pKa = 11.84HH4928 pKa = 3.95WRR4930 pKa = 11.84MKK4932 pKa = 9.1GTYY4935 pKa = 7.97TRR4937 pKa = 11.84SKK4939 pKa = 10.1RR4940 pKa = 11.84DD4941 pKa = 3.61FMRR4944 pKa = 11.84MTGQATTALGNVITNFQVHH4963 pKa = 5.83CRR4965 pKa = 11.84FVLRR4969 pKa = 11.84NQHH4972 pKa = 6.73RR4973 pKa = 11.84ILFMLFLGDD4982 pKa = 3.81DD4983 pKa = 3.29MLMFFSEE4990 pKa = 4.38KK4991 pKa = 10.15PDD4993 pKa = 3.21IKK4995 pKa = 10.85GLRR4998 pKa = 11.84NEE5000 pKa = 3.71IAVYY5004 pKa = 10.56FNMQSKK5010 pKa = 10.92DD5011 pKa = 4.08SINEE5015 pKa = 3.96LYY5017 pKa = 9.48GTFCGMLAYY5026 pKa = 8.16HH5027 pKa = 6.48TSEE5030 pKa = 4.46TTCEE5034 pKa = 3.94LGPDD5038 pKa = 4.19FMRR5041 pKa = 11.84LKK5043 pKa = 10.92YY5044 pKa = 10.33RR5045 pKa = 11.84FEE5047 pKa = 4.23VTNGVHH5053 pKa = 6.77EE5054 pKa = 5.14DD5055 pKa = 3.11SDD5057 pKa = 4.69LNMRR5061 pKa = 11.84MRR5063 pKa = 11.84TMSYY5067 pKa = 11.08CMMLGDD5073 pKa = 3.65ISEE5076 pKa = 4.21VRR5078 pKa = 11.84HH5079 pKa = 5.98VIDD5082 pKa = 3.67STGLPIQPVSWYY5094 pKa = 9.8SKK5096 pKa = 8.1PHH5098 pKa = 5.7AMQAAAHH5105 pKa = 6.18KK5106 pKa = 10.05HH5107 pKa = 5.07NSTPIQIGGVLHH5119 pKa = 6.46SLCQMMKK5126 pKa = 10.16DD5127 pKa = 2.82AKK5129 pKa = 9.93TFHH5132 pKa = 6.21TTFKK5136 pKa = 9.96MYY5138 pKa = 9.68TSKK5141 pKa = 10.65PRR5143 pKa = 11.84WW5144 pKa = 3.24

Molecular weight: 577.36 kDa
Isoelectric point according different methods:

Protein with the highest isoelectric point:

>tr|A0A1L3KK54|A0A1L3KK54_9VIRU RdRp catalytic domain-containing protein OS=Shahe endorna-like virus 1 OX=1923414 PE=4 SV=1

MM1 pKa = 7.36MLLNMYY7 pKa = 9.91GATTPLEE14 pKa = 3.94GRR16 pKa = 11.84IDD18 pKa = 3.79LQYY21 pKa = 11.25LNPKK25 pKa = 9.86IIGKK29 pKa = 8.82IVWMYY34 pKa = 11.08KK35 pKa = 9.9NNEE38 pKa = 4.24LFTDD42 pKa = 4.24LTDD45 pKa = 4.08DD46 pKa = 4.69QYY48 pKa = 12.07NNWKK52 pKa = 9.7VRR54 pKa = 11.84VRR56 pKa = 11.84HH57 pKa = 6.07NYY59 pKa = 8.65LAPLRR64 pKa = 11.84DD65 pKa = 3.51YY66 pKa = 11.09EE67 pKa = 4.98DD68 pKa = 4.28RR69 pKa = 11.84YY70 pKa = 10.79LYY72 pKa = 10.63HH73 pKa = 8.1LGIDD77 pKa = 4.06PQTVTAPSPKK87 pKa = 9.67PSGARR92 pKa = 11.84LMEE95 pKa = 4.15KK96 pKa = 10.35LAIEE100 pKa = 4.01MRR102 pKa = 11.84KK103 pKa = 8.93FATATQRR110 pKa = 11.84VKK112 pKa = 10.95HH113 pKa = 5.23GVEE116 pKa = 3.88RR117 pKa = 11.84HH118 pKa = 5.97NGWEE122 pKa = 4.02QYY124 pKa = 10.58ILACATARR132 pKa = 11.84PDD134 pKa = 4.75AMGQALNIRR143 pKa = 11.84GRR145 pKa = 11.84MDD147 pKa = 3.46TNPCVAPVMVCGVCSAPNLMSHH169 pKa = 6.9HH170 pKa = 7.5DD171 pKa = 4.12SPCVYY176 pKa = 10.42LPQSWVKK183 pKa = 10.76DD184 pKa = 3.56YY185 pKa = 11.53AKK187 pKa = 10.34QHH189 pKa = 6.28LLPEE193 pKa = 4.38NTWDD197 pKa = 4.56DD198 pKa = 4.4SEE200 pKa = 4.33LHH202 pKa = 6.69NYY204 pKa = 9.62DD205 pKa = 3.52LQTPVHH211 pKa = 5.79TPVIRR216 pKa = 11.84STKK219 pKa = 9.61QKK221 pKa = 9.56LTVTEE226 pKa = 4.23EE227 pKa = 4.24EE228 pKa = 4.19EE229 pKa = 4.48VAWRR233 pKa = 11.84CGACFADD240 pKa = 5.3LGILVIDD247 pKa = 3.18QWITFDD253 pKa = 5.66LVLQAISDD261 pKa = 4.16PDD263 pKa = 4.03PPVMGLLEE271 pKa = 4.14YY272 pKa = 10.38LKK274 pKa = 10.9LMRR277 pKa = 11.84YY278 pKa = 10.02GDD280 pKa = 4.72FIDD283 pKa = 5.45EE284 pKa = 4.09ISKK287 pKa = 10.52QEE289 pKa = 4.01GEE291 pKa = 4.59TIMKK295 pKa = 9.62HH296 pKa = 6.03DD297 pKa = 3.45RR298 pKa = 11.84TIVKK302 pKa = 10.0RR303 pKa = 11.84ALRR306 pKa = 11.84DD307 pKa = 3.3ASTKK311 pKa = 10.62LITVGPDD318 pKa = 3.04VPPEE322 pKa = 4.09LFTEE326 pKa = 4.48LNRR329 pKa = 11.84LYY331 pKa = 9.78VKK333 pKa = 10.64CVARR337 pKa = 11.84PLACKK342 pKa = 9.92TSMSPQLATEE352 pKa = 4.41LAYY355 pKa = 10.58ADD357 pKa = 3.64SWVSAKK363 pKa = 10.67LNSTDD368 pKa = 3.33QLLKK372 pKa = 10.41IGSLSWEE379 pKa = 3.86YY380 pKa = 10.88RR381 pKa = 11.84PGNHH385 pKa = 6.2HH386 pKa = 6.65HH387 pKa = 6.79WNYY390 pKa = 10.8NPILMGQYY398 pKa = 9.54IGEE401 pKa = 4.36GLCFTTGPCEE411 pKa = 4.32HH412 pKa = 7.38KK413 pKa = 10.24LHH415 pKa = 6.65CPAVFGMGALNDD427 pKa = 3.81TLTNFMSAVKK437 pKa = 9.71NQSDD441 pKa = 4.25AYY443 pKa = 10.83LILLNPGQKK452 pKa = 10.61LLGPLTSNLGYY463 pKa = 10.36IKK465 pKa = 10.74DD466 pKa = 3.64NGEE469 pKa = 3.94CLEE472 pKa = 4.24IYY474 pKa = 10.03IDD476 pKa = 3.54GTMYY480 pKa = 10.52PLVVNKK486 pKa = 9.81EE487 pKa = 4.07LYY489 pKa = 9.88EE490 pKa = 3.95VLINSDD496 pKa = 4.57AIVDD500 pKa = 4.06GNDD503 pKa = 3.46CYY505 pKa = 11.81SLLTVKK511 pKa = 10.54KK512 pKa = 10.45GIDD515 pKa = 3.51VVIKK519 pKa = 10.61HH520 pKa = 5.95IMGPVNQEE528 pKa = 4.25SIGKK532 pKa = 8.58LVNVSTPTKK541 pKa = 9.7KK542 pKa = 10.43KK543 pKa = 10.1IVMPVPDD550 pKa = 3.84TTGVMGLWTALAYY563 pKa = 9.74KK564 pKa = 10.28DD565 pKa = 4.86LEE567 pKa = 4.23IDD569 pKa = 4.19FEE571 pKa = 5.57PGLFRR576 pKa = 11.84EE577 pKa = 4.2LCIRR581 pKa = 11.84NFTGKK586 pKa = 10.22CGRR589 pKa = 11.84DD590 pKa = 3.19DD591 pKa = 3.92LMSYY595 pKa = 10.64GMGYY599 pKa = 10.9ALTRR603 pKa = 11.84FTVHH607 pKa = 5.35NTVIHH612 pKa = 6.12NPQVCASQIQIHH624 pKa = 5.83VFLCQVTMGVANSRR638 pKa = 11.84AAINNQALTLLSKK651 pKa = 10.94LGPLKK656 pKa = 10.94SIVTGHH662 pKa = 7.17LEE664 pKa = 4.07SLDD667 pKa = 3.55DD668 pKa = 4.5AVRR671 pKa = 11.84TGIKK675 pKa = 8.99WLAEE679 pKa = 4.32SKK681 pKa = 10.69FSLDD685 pKa = 4.13FEE687 pKa = 5.69NIMNTLTEE695 pKa = 4.02VQINEE700 pKa = 4.18WVSGITKK707 pKa = 6.71THH709 pKa = 5.15IWEE712 pKa = 4.59DD713 pKa = 3.27LLDD716 pKa = 4.02IVNSYY721 pKa = 10.32PVGDD725 pKa = 3.93VKK727 pKa = 10.95VHH729 pKa = 5.29VMHH732 pKa = 6.87KK733 pKa = 9.94PSALRR738 pKa = 11.84TLPSHH743 pKa = 6.84RR744 pKa = 11.84CHH746 pKa = 5.81HH747 pKa = 6.49HH748 pKa = 6.04SWGCDD753 pKa = 2.79HH754 pKa = 6.97TSINTSEE761 pKa = 4.48LCEE764 pKa = 4.28CCGMPTPEE772 pKa = 4.62EE773 pKa = 5.22GYY775 pKa = 10.38CICCMPKK782 pKa = 9.62PDD784 pKa = 4.89LEE786 pKa = 4.64HH787 pKa = 7.32EE788 pKa = 4.25YY789 pKa = 11.16GIDD792 pKa = 3.39LFNVVDD798 pKa = 3.96PKK800 pKa = 11.42SRR802 pKa = 11.84VKK804 pKa = 10.44EE805 pKa = 3.91VSDD808 pKa = 4.32VITKK812 pKa = 7.82EE813 pKa = 4.32VKK815 pKa = 9.15TSRR818 pKa = 11.84VDD820 pKa = 3.25KK821 pKa = 11.05SNSEE825 pKa = 4.09SLMAAFIKK833 pKa = 10.3QISRR837 pKa = 11.84IGLKK841 pKa = 10.67DD842 pKa = 3.46RR843 pKa = 11.84DD844 pKa = 4.24EE845 pKa = 4.44KK846 pKa = 11.34EE847 pKa = 3.62KK848 pKa = 10.49TPRR851 pKa = 11.84IDD853 pKa = 3.3LSKK856 pKa = 9.83TPRR859 pKa = 11.84LTAVNSTQAKK869 pKa = 6.22STKK872 pKa = 10.08RR873 pKa = 11.84KK874 pKa = 9.66GKK876 pKa = 7.68TAAKK880 pKa = 9.8PDD882 pKa = 3.78EE883 pKa = 4.45TDD885 pKa = 3.71LRR887 pKa = 11.84PSSTTPAPPTADD899 pKa = 3.23VLDD902 pKa = 4.63EE903 pKa = 4.31VPGTQVCDD911 pKa = 3.52ATDD914 pKa = 3.34VTNNAGEE921 pKa = 4.21FVTDD925 pKa = 3.84DD926 pKa = 4.33VEE928 pKa = 4.43GQSIDD933 pKa = 3.61QEE935 pKa = 4.09EE936 pKa = 4.88LEE938 pKa = 4.36RR939 pKa = 11.84KK940 pKa = 9.05IAVAEE945 pKa = 3.97EE946 pKa = 4.01LKK948 pKa = 10.59RR949 pKa = 11.84LYY951 pKa = 10.38RR952 pKa = 11.84SRR954 pKa = 11.84THH956 pKa = 5.4NHH958 pKa = 4.41QEE960 pKa = 3.91KK961 pKa = 10.3VAATHH966 pKa = 5.14LTEE969 pKa = 4.88NKK971 pKa = 9.96VNTLNPSYY979 pKa = 10.88DD980 pKa = 3.35YY981 pKa = 11.6SDD983 pKa = 3.62YY984 pKa = 11.26FNLLGAEE991 pKa = 4.32FATYY995 pKa = 10.91LLDD998 pKa = 4.76RR999 pKa = 11.84EE1000 pKa = 4.26QSLIDD1005 pKa = 3.68LQAAKK1010 pKa = 9.25TKK1012 pKa = 8.99PYY1014 pKa = 10.49EE1015 pKa = 4.02VIIPYY1020 pKa = 9.98VPIGIHH1026 pKa = 5.14NHH1028 pKa = 4.34TDD1030 pKa = 2.31QWMEE1034 pKa = 3.64VLSRR1038 pKa = 11.84INVSNTYY1045 pKa = 10.84DD1046 pKa = 3.48NSCGLDD1052 pKa = 2.9AYY1054 pKa = 11.23NYY1056 pKa = 7.04VTGRR1060 pKa = 11.84GLSRR1064 pKa = 11.84EE1065 pKa = 4.33EE1066 pKa = 3.72ILSLIGVDD1074 pKa = 4.07NNLLTTDD1081 pKa = 4.71LANLADD1087 pKa = 3.77ACGDD1091 pKa = 3.54NLILITEE1098 pKa = 4.69LSVITCKK1105 pKa = 10.69YY1106 pKa = 9.84SEE1108 pKa = 4.24SDD1110 pKa = 3.63VFPVIVLDD1118 pKa = 3.78STSPDD1123 pKa = 3.27NGHH1126 pKa = 6.34YY1127 pKa = 10.65SPAIVLLRR1135 pKa = 11.84NDD1137 pKa = 3.66PGFYY1141 pKa = 10.28AIRR1144 pKa = 11.84AGPSLEE1150 pKa = 4.03SFRR1153 pKa = 11.84TDD1155 pKa = 2.56ILTLKK1160 pKa = 10.41GLNQGCLFGRR1170 pKa = 11.84TPITAQDD1177 pKa = 3.57NLIIEE1182 pKa = 4.92LTTKK1186 pKa = 10.14QCSDD1190 pKa = 3.96DD1191 pKa = 4.08LDD1193 pKa = 3.82NAVISIRR1200 pKa = 11.84TPEE1203 pKa = 3.68VRR1205 pKa = 11.84RR1206 pKa = 11.84IGDD1209 pKa = 3.73GYY1211 pKa = 11.36YY1212 pKa = 8.77FTNSPGGIHH1221 pKa = 6.89KK1222 pKa = 9.87PGHH1225 pKa = 5.92HH1226 pKa = 7.14LYY1228 pKa = 10.2HH1229 pKa = 6.51KK1230 pKa = 9.69PIRR1233 pKa = 11.84EE1234 pKa = 4.18SILNVIEE1241 pKa = 4.6AMSTTEE1247 pKa = 3.96PNMALKK1253 pKa = 10.81SNLLNTIFNRR1263 pKa = 11.84EE1264 pKa = 3.52PRR1266 pKa = 11.84IADD1269 pKa = 3.51NLVQEE1274 pKa = 4.53YY1275 pKa = 9.85DD1276 pKa = 3.57HH1277 pKa = 6.89KK1278 pKa = 11.38VRR1280 pKa = 11.84EE1281 pKa = 4.34AVKK1284 pKa = 10.63SVIDD1288 pKa = 3.85LQVAFGDD1295 pKa = 3.42GRR1297 pKa = 11.84MPSKK1301 pKa = 10.39VKK1303 pKa = 9.7SWHH1306 pKa = 5.86KK1307 pKa = 10.5VEE1309 pKa = 5.26CKK1311 pKa = 10.62ASGKK1315 pKa = 5.8WTSIINPCPKK1325 pKa = 10.29LKK1327 pKa = 9.94TLDD1330 pKa = 3.03WVYY1333 pKa = 9.81ITNKK1337 pKa = 9.33SGSYY1341 pKa = 9.68LRR1343 pKa = 11.84QVVIDD1348 pKa = 3.66RR1349 pKa = 11.84TRR1351 pKa = 11.84LLVASLGRR1359 pKa = 11.84QCDD1362 pKa = 3.75GSKK1365 pKa = 10.68LGVLDD1370 pKa = 3.86TSVASAIKK1378 pKa = 10.44CIATYY1383 pKa = 10.53CSTVPDD1389 pKa = 3.8GKK1391 pKa = 10.65KK1392 pKa = 9.66IRR1394 pKa = 11.84EE1395 pKa = 4.19LLANAIVIDD1404 pKa = 4.46GVAGHH1409 pKa = 6.68GKK1411 pKa = 10.17SNAIAQEE1418 pKa = 4.55CNTSDD1423 pKa = 3.6LVIAKK1428 pKa = 7.61THH1430 pKa = 6.1LAVAGLRR1437 pKa = 11.84AKK1439 pKa = 8.77ITKK1442 pKa = 9.51RR1443 pKa = 11.84VNVLSIEE1450 pKa = 4.28RR1451 pKa = 11.84AVGDD1455 pKa = 4.03PPHH1458 pKa = 7.18HH1459 pKa = 5.46YY1460 pKa = 9.43TRR1462 pKa = 11.84IIIDD1466 pKa = 3.66EE1467 pKa = 4.47ASMVDD1472 pKa = 3.81YY1473 pKa = 11.18IEE1475 pKa = 4.26ICPLISAEE1483 pKa = 4.08VTEE1486 pKa = 4.5LKK1488 pKa = 10.73LYY1490 pKa = 10.75GDD1492 pKa = 4.0SRR1494 pKa = 11.84QIGNRR1499 pKa = 11.84DD1500 pKa = 3.36FSSSGGVRR1508 pKa = 11.84HH1509 pKa = 5.92TLNLMDD1515 pKa = 4.99LAGSAHH1521 pKa = 5.55VSKK1524 pKa = 10.69EE1525 pKa = 3.87NQSYY1529 pKa = 10.63RR1530 pKa = 11.84IGYY1533 pKa = 7.2PAAEE1537 pKa = 4.47YY1538 pKa = 10.24VQQLYY1543 pKa = 10.63PEE1545 pKa = 4.3FTGTTEE1551 pKa = 4.22HH1552 pKa = 6.08NTGFQIVHH1560 pKa = 5.81VNPDD1564 pKa = 3.33NVEE1567 pKa = 3.98KK1568 pKa = 10.96LRR1570 pKa = 11.84DD1571 pKa = 4.7DD1572 pKa = 3.25ILMAKK1577 pKa = 9.55FDD1579 pKa = 4.04VVITFYY1585 pKa = 11.47NHH1587 pKa = 4.9TKK1589 pKa = 10.22ILLEE1593 pKa = 3.96KK1594 pKa = 9.99LLPKK1598 pKa = 9.92EE1599 pKa = 4.29VPVVTAHH1606 pKa = 6.88SYY1608 pKa = 9.58QGRR1611 pKa = 11.84EE1612 pKa = 4.05ANRR1615 pKa = 11.84VAVVQWPDD1623 pKa = 2.9ANGNMTLCRR1632 pKa = 11.84HH1633 pKa = 5.21MNYY1636 pKa = 9.44MYY1638 pKa = 10.11TAVTRR1643 pKa = 11.84GISQTTLYY1651 pKa = 10.54TSLNVDD1657 pKa = 4.39DD1658 pKa = 5.6NPSLSQLVTMGGQGHH1673 pKa = 6.13TRR1675 pKa = 11.84YY1676 pKa = 9.52QPPTTTDD1683 pKa = 2.71KK1684 pKa = 11.38YY1685 pKa = 10.47LTRR1688 pKa = 11.84LDD1690 pKa = 4.51KK1691 pKa = 10.75ISLRR1695 pKa = 11.84NSHH1698 pKa = 6.22LWEE1701 pKa = 5.61DD1702 pKa = 4.33DD1703 pKa = 4.45LIQALQGNKK1712 pKa = 10.34DD1713 pKa = 3.49KK1714 pKa = 10.95DD1715 pKa = 3.94GKK1717 pKa = 10.91SITVKK1722 pKa = 9.94RR1723 pKa = 11.84TDD1725 pKa = 2.99TATIISVMDD1734 pKa = 4.12GKK1736 pKa = 10.43NKK1738 pKa = 10.24KK1739 pKa = 9.32IGYY1742 pKa = 8.22FVNEE1746 pKa = 4.45GGNLTANFGFGLANMVAMSKK1766 pKa = 10.48VDD1768 pKa = 3.79DD1769 pKa = 4.28LVVDD1773 pKa = 4.18VKK1775 pKa = 11.37DD1776 pKa = 3.45GGVYY1780 pKa = 10.39NRR1782 pKa = 11.84DD1783 pKa = 3.61TKK1785 pKa = 9.28THH1787 pKa = 6.1IAGPLAKK1794 pKa = 10.38DD1795 pKa = 3.37KK1796 pKa = 11.33TNLEE1800 pKa = 4.04HH1801 pKa = 7.42LYY1803 pKa = 10.2VEE1805 pKa = 4.37EE1806 pKa = 3.54MLYY1809 pKa = 10.11PVEE1812 pKa = 5.18HH1813 pKa = 6.9RR1814 pKa = 11.84PPLNKK1819 pKa = 9.84IMDD1822 pKa = 4.02HH1823 pKa = 5.06VACPNSMWKK1832 pKa = 8.1TVLVPTVQQMCKK1844 pKa = 9.47IRR1846 pKa = 11.84MATYY1850 pKa = 9.3MCDD1853 pKa = 3.33CSLPNHH1859 pKa = 6.94SITYY1863 pKa = 5.64TTPDD1867 pKa = 3.4GPITMSKK1874 pKa = 9.29TEE1876 pKa = 4.21GCPLACGLKK1885 pKa = 10.5LEE1887 pKa = 4.75FKK1889 pKa = 10.7GSVVNISSQYY1899 pKa = 8.45RR1900 pKa = 11.84NWWTRR1905 pKa = 11.84SISVTGRR1912 pKa = 11.84WGQNGRR1918 pKa = 11.84QLLTAVGKK1926 pKa = 9.02WLGVKK1931 pKa = 9.66IPKK1934 pKa = 10.17DD1935 pKa = 3.38LTDD1938 pKa = 3.69NCHH1941 pKa = 6.0EE1942 pKa = 4.41LSIPVYY1948 pKa = 9.69PSTAISARR1956 pKa = 11.84LYY1958 pKa = 10.48AEE1960 pKa = 4.29RR1961 pKa = 11.84MSHH1964 pKa = 7.17GIFGIANLLNMHH1976 pKa = 6.94KK1977 pKa = 9.44VTADD1981 pKa = 3.57CADD1984 pKa = 3.77GEE1986 pKa = 4.51AVQTAEE1992 pKa = 5.28RR1993 pKa = 11.84ITSHH1997 pKa = 6.28YY1998 pKa = 9.38KK1999 pKa = 9.95LHH2001 pKa = 6.56SGNIKK2006 pKa = 9.68VRR2008 pKa = 11.84SPHH2011 pKa = 5.42KK2012 pKa = 8.95TWLVHH2017 pKa = 5.18HH2018 pKa = 7.14KK2019 pKa = 10.25KK2020 pKa = 10.54RR2021 pKa = 11.84GWIRR2025 pKa = 11.84NYY2027 pKa = 10.7DD2028 pKa = 3.86VISIGPACRR2037 pKa = 11.84PWIEE2041 pKa = 4.0RR2042 pKa = 11.84QSISVEE2048 pKa = 3.7LMSYY2052 pKa = 9.47LVEE2055 pKa = 4.51MIEE2058 pKa = 4.31KK2059 pKa = 10.15DD2060 pKa = 3.36LAGKK2064 pKa = 8.65VEE2066 pKa = 4.28KK2067 pKa = 10.6PEE2069 pKa = 3.88FDD2071 pKa = 3.25AVGSFDD2077 pKa = 4.6LEE2079 pKa = 4.44GMILDD2084 pKa = 3.92VNYY2087 pKa = 10.36HH2088 pKa = 5.45ITNDD2092 pKa = 3.37TSVGKK2097 pKa = 8.98EE2098 pKa = 3.83LKK2100 pKa = 10.27RR2101 pKa = 11.84SAGHH2105 pKa = 6.18ISQYY2109 pKa = 7.69TTVKK2113 pKa = 10.04PKK2115 pKa = 8.95EE2116 pKa = 3.88HH2117 pKa = 6.24LVISEE2122 pKa = 3.74VGMRR2126 pKa = 11.84EE2127 pKa = 3.89LRR2129 pKa = 11.84SEE2131 pKa = 4.29LKK2133 pKa = 10.63DD2134 pKa = 3.55AFPLMHH2140 pKa = 6.57VNPHH2144 pKa = 4.55SHH2146 pKa = 7.31AISGSYY2152 pKa = 10.12VEE2154 pKa = 4.81EE2155 pKa = 4.69CLDD2158 pKa = 3.5SLAINIVGEE2167 pKa = 4.25TFEE2170 pKa = 4.5TCDD2173 pKa = 3.31LSYY2176 pKa = 10.6VGKK2179 pKa = 9.12MPHH2182 pKa = 6.26IPYY2185 pKa = 10.03VLNKK2189 pKa = 9.99HH2190 pKa = 4.67YY2191 pKa = 11.23VKK2193 pKa = 10.94LITPASHH2200 pKa = 5.11YY2201 pKa = 7.24THH2203 pKa = 5.85YY2204 pKa = 10.95HH2205 pKa = 5.07EE2206 pKa = 4.35WHH2208 pKa = 6.73EE2209 pKa = 4.3SLNLAKK2215 pKa = 9.57TLHH2218 pKa = 5.93HH2219 pKa = 6.83NYY2221 pKa = 9.48RR2222 pKa = 11.84EE2223 pKa = 4.14AMHH2226 pKa = 6.92ASEE2229 pKa = 5.35PDD2231 pKa = 3.34MTVKK2235 pKa = 10.48PFGTIQPPDD2244 pKa = 3.42SGTIIVAGTSLHH2256 pKa = 6.95AIPYY2260 pKa = 8.89HH2261 pKa = 6.89DD2262 pKa = 4.45LRR2264 pKa = 11.84SWMAEE2269 pKa = 3.8GKK2271 pKa = 10.06RR2272 pKa = 11.84VFGWVPDD2279 pKa = 3.74FTNGSEE2285 pKa = 4.36RR2286 pKa = 11.84FYY2288 pKa = 10.82TPEE2291 pKa = 3.84KK2292 pKa = 9.9TSTGANITYY2301 pKa = 10.25HH2302 pKa = 6.88LGHH2305 pKa = 6.88KK2306 pKa = 10.03PSAVDD2311 pKa = 3.53RR2312 pKa = 11.84KK2313 pKa = 10.19LLEE2316 pKa = 4.14MCNMGRR2322 pKa = 11.84PIIQDD2327 pKa = 3.44NEE2329 pKa = 3.63PSIICRR2335 pKa = 11.84HH2336 pKa = 5.41IKK2338 pKa = 10.27SVLGHH2343 pKa = 6.57KK2344 pKa = 9.89LVEE2347 pKa = 4.71VILSTKK2353 pKa = 9.63EE2354 pKa = 3.67RR2355 pKa = 11.84FNVQLEE2361 pKa = 4.38SMVMSGTKK2369 pKa = 10.47VNVDD2373 pKa = 3.76LPFINLDD2380 pKa = 3.55PVQLLSGGPVVQVKK2394 pKa = 10.15RR2395 pKa = 11.84YY2396 pKa = 6.67TICKK2400 pKa = 9.57KK2401 pKa = 10.38LLRR2404 pKa = 11.84LLQLRR2409 pKa = 11.84MAQPGCKK2416 pKa = 7.84TTDD2419 pKa = 3.23VLSYY2423 pKa = 10.96ARR2425 pKa = 11.84SLASACEE2432 pKa = 3.78ITDD2435 pKa = 3.19RR2436 pKa = 11.84SIRR2439 pKa = 11.84YY2440 pKa = 6.06THH2442 pKa = 7.34DD2443 pKa = 3.23VDD2445 pKa = 5.73LKK2447 pKa = 10.09CLHH2450 pKa = 6.11HH2451 pKa = 5.95TAYY2454 pKa = 10.66LAVYY2458 pKa = 8.85LQGHH2462 pKa = 5.1MKK2464 pKa = 9.89EE2465 pKa = 4.17RR2466 pKa = 11.84YY2467 pKa = 8.13HH2468 pKa = 6.28WLSSVWDD2475 pKa = 4.1LLRR2478 pKa = 11.84KK2479 pKa = 9.85NDD2481 pKa = 4.6GIAANAQVILGGFAKK2496 pKa = 9.73ICSMFSDD2503 pKa = 3.85AVSEE2507 pKa = 3.97FLQPEE2512 pKa = 4.58LLNTILNNKK2521 pKa = 9.06KK2522 pKa = 10.52LGITNAEE2529 pKa = 4.35LKK2531 pKa = 10.49RR2532 pKa = 11.84LEE2534 pKa = 4.8GEE2536 pKa = 4.27LQAKK2540 pKa = 9.12LNWQNRR2546 pKa = 11.84YY2547 pKa = 6.13WVQYY2551 pKa = 8.03TNHH2554 pKa = 6.17HH2555 pKa = 5.81VSRR2558 pKa = 11.84NPSTTQTNHH2567 pKa = 5.4GLEE2570 pKa = 4.37SEE2572 pKa = 5.05DD2573 pKa = 5.31GGEE2576 pKa = 3.87DD2577 pKa = 2.5WWNNEE2582 pKa = 3.49RR2583 pKa = 11.84DD2584 pKa = 3.78DD2585 pKa = 5.2NYY2587 pKa = 9.91FTTVAEE2593 pKa = 4.56DD2594 pKa = 3.65DD2595 pKa = 3.85EE2596 pKa = 5.59LYY2598 pKa = 11.01NLQSHH2603 pKa = 5.67TQVEE2607 pKa = 5.02SKK2609 pKa = 10.7LHH2611 pKa = 4.26GHH2613 pKa = 6.09INKK2616 pKa = 9.31EE2617 pKa = 3.96LLVNSPNQYY2626 pKa = 11.01AKK2628 pKa = 9.49EE2629 pKa = 4.17TVPTATCEE2637 pKa = 3.96FGKK2640 pKa = 9.53QHH2642 pKa = 5.95QPVIDD2647 pKa = 3.88SCVEE2651 pKa = 3.78LTTQNQLVDD2660 pKa = 4.63LGQSPSIEE2668 pKa = 3.67IVVRR2672 pKa = 11.84EE2673 pKa = 4.29LGSPRR2678 pKa = 11.84AVMEE2682 pKa = 4.55SYY2684 pKa = 11.05GQIQTDD2690 pKa = 3.77TCSPPTKK2697 pKa = 10.25LRR2699 pKa = 11.84TEE2701 pKa = 4.29VAVKK2705 pKa = 10.15SQQLEE2710 pKa = 4.08PGVQTRR2716 pKa = 11.84SDD2718 pKa = 3.65TTPNDD2723 pKa = 3.13IPYY2726 pKa = 9.51KK2727 pKa = 10.27PPGGHH2732 pKa = 6.43DD2733 pKa = 3.78TIPPQNTSPSNQKK2746 pKa = 10.14LKK2748 pKa = 11.06SGTTEE2753 pKa = 3.79LTEE2756 pKa = 4.57NPPNMDD2762 pKa = 3.11GTKK2765 pKa = 10.21EE2766 pKa = 3.96IFDD2769 pKa = 4.77DD2770 pKa = 4.25ADD2772 pKa = 3.42EE2773 pKa = 4.3FHH2775 pKa = 7.27DD2776 pKa = 4.26AKK2778 pKa = 11.05EE2779 pKa = 4.53SISDD2783 pKa = 3.58LDD2785 pKa = 3.77SRR2787 pKa = 11.84YY2788 pKa = 10.32EE2789 pKa = 3.97DD2790 pKa = 3.44YY2791 pKa = 11.03LYY2793 pKa = 11.57NLLGEE2798 pKa = 4.69SNTEE2802 pKa = 3.54EE2803 pKa = 4.26RR2804 pKa = 11.84QDD2806 pKa = 3.46LKK2808 pKa = 11.4NRR2810 pKa = 11.84FWFDD2814 pKa = 2.77KK2815 pKa = 10.41KK2816 pKa = 10.78LRR2818 pKa = 11.84GYY2820 pKa = 10.26FISQEE2825 pKa = 3.98RR2826 pKa = 11.84LNQYY2830 pKa = 8.56STDD2833 pKa = 3.72PDD2835 pKa = 3.48QQAEE2839 pKa = 4.06LSGFIDD2845 pKa = 3.79KK2846 pKa = 11.13GLDD2849 pKa = 3.43LSRR2852 pKa = 11.84SDD2854 pKa = 5.59AGDD2857 pKa = 3.21QVDD2860 pKa = 4.77RR2861 pKa = 11.84YY2862 pKa = 10.83AVITTSLFEE2871 pKa = 4.93DD2872 pKa = 4.18PGVLPTDD2879 pKa = 3.89STHH2882 pKa = 6.7DD2883 pKa = 3.7TQSSSVEE2890 pKa = 4.08STQEE2894 pKa = 3.55LVTALEE2900 pKa = 4.22EE2901 pKa = 4.56SPADD2905 pKa = 3.34TCIPSRR2911 pKa = 11.84PDD2913 pKa = 4.14DD2914 pKa = 3.59INIQIVEE2921 pKa = 4.22PAATPHH2927 pKa = 7.15ADD2929 pKa = 3.51PCEE2932 pKa = 4.2LSPKK2936 pKa = 10.21LDD2938 pKa = 4.03TPPSTQSVEE2947 pKa = 4.22VGLSSQDD2954 pKa = 3.15TMTHH2958 pKa = 6.15EE2959 pKa = 4.38EE2960 pKa = 4.42TLTSLTNTIDD2970 pKa = 3.38TTNQSDD2976 pKa = 3.82DD2977 pKa = 3.26TGTPFKK2983 pKa = 10.24TRR2985 pKa = 11.84LSMIPIPRR2993 pKa = 11.84KK2994 pKa = 9.93KK2995 pKa = 10.02PPTHH2999 pKa = 5.9STPTRR3004 pKa = 11.84PWDD3007 pKa = 3.28RR3008 pKa = 11.84TTQTEE3013 pKa = 4.34PGPTPHH3019 pKa = 5.5VQNRR3023 pKa = 11.84KK3024 pKa = 7.04TPSPVSSKK3032 pKa = 10.54HH3033 pKa = 4.79MKK3035 pKa = 9.81YY3036 pKa = 10.8DD3037 pKa = 3.42HH3038 pKa = 7.45LDD3040 pKa = 3.71TNFHH3044 pKa = 5.99GAEE3047 pKa = 3.88ISHH3050 pKa = 7.05ASNLQNMIRR3059 pKa = 11.84DD3060 pKa = 3.65IDD3062 pKa = 3.72RR3063 pKa = 11.84LSIMEE3068 pKa = 4.07VSDD3071 pKa = 3.43TTEE3074 pKa = 3.8SGTPPAHH3081 pKa = 7.54DD3082 pKa = 5.83DD3083 pKa = 3.2IAKK3086 pKa = 10.36EE3087 pKa = 4.33SIEE3090 pKa = 4.12HH3091 pKa = 6.13ATDD3094 pKa = 3.66QEE3096 pKa = 4.81YY3097 pKa = 11.16VWLISVGSSGDD3108 pKa = 3.39IVAMDD3113 pKa = 4.39PVAEE3117 pKa = 4.31SLMPDD3122 pKa = 3.53YY3123 pKa = 10.78KK3124 pKa = 11.15VVVATHH3130 pKa = 6.87FDD3132 pKa = 3.46LMHH3135 pKa = 6.63CVPEE3139 pKa = 4.41GQGKK3143 pKa = 9.69VMLPISSKK3151 pKa = 10.06VVMKK3155 pKa = 10.79AVVDD3159 pKa = 3.85NLTKK3163 pKa = 10.85GMIHH3167 pKa = 6.31MFSTGPKK3174 pKa = 8.39TIKK3177 pKa = 10.6LMAEE3181 pKa = 4.06VIEE3184 pKa = 4.15PLFNIKK3190 pKa = 10.31PNVSLIVSNHH3200 pKa = 4.3FTPLVGLLAAHH3211 pKa = 7.27WGCKK3215 pKa = 8.83LVHH3218 pKa = 7.01AYY3220 pKa = 10.27AFDD3223 pKa = 4.84PDD3225 pKa = 4.47CVDD3228 pKa = 4.84SFALHH3233 pKa = 6.25PKK3235 pKa = 9.62INSAPMVKK3243 pKa = 10.36EE3244 pKa = 3.57MINPIKK3250 pKa = 10.28ATILRR3255 pKa = 11.84ALDD3258 pKa = 3.65FSMANQLNINCPNPIDD3274 pKa = 3.61IAATPKK3280 pKa = 10.71LITSSEE3286 pKa = 3.87LMASDD3291 pKa = 3.99EE3292 pKa = 4.56STNKK3296 pKa = 8.92WGKK3299 pKa = 10.56LYY3301 pKa = 10.34IGSTARR3307 pKa = 11.84TGCVAGNSAEE3317 pKa = 4.09TMKK3320 pKa = 10.62FVSTGSITLITWGSVYY3336 pKa = 10.62SEE3338 pKa = 4.37YY3339 pKa = 10.76NQSILQDD3346 pKa = 3.8LVVHH3350 pKa = 6.79TINSGSKK3357 pKa = 10.23VLFNNYY3363 pKa = 8.87KK3364 pKa = 10.32KK3365 pKa = 10.75LYY3367 pKa = 8.93TLDD3370 pKa = 3.23KK3371 pKa = 10.23VKK3373 pKa = 10.78VVTLCKK3379 pKa = 10.09PNSCAMDD3386 pKa = 3.54RR3387 pKa = 11.84LLIVEE3392 pKa = 4.31SLDD3395 pKa = 3.59YY3396 pKa = 11.35NLVLPRR3402 pKa = 11.84CKK3404 pKa = 10.4AIVHH3408 pKa = 6.37HH3409 pKa = 6.65GGSGTTHH3416 pKa = 5.84QAVSYY3421 pKa = 9.32DD3422 pKa = 3.94VPSLILPIFGDD3433 pKa = 3.64QFWWSKK3439 pKa = 10.04RR3440 pKa = 11.84VNDD3443 pKa = 3.63LRR3445 pKa = 11.84IGIGLEE3451 pKa = 3.89AEE3453 pKa = 4.34SPITVVNKK3461 pKa = 10.37AVTRR3465 pKa = 11.84LLTRR3469 pKa = 11.84NQDD3472 pKa = 3.1YY3473 pKa = 10.44RR3474 pKa = 11.84KK3475 pKa = 10.31AIISSKK3481 pKa = 11.0LNLLFNRR3488 pKa = 11.84EE3489 pKa = 3.99MCRR3492 pKa = 11.84HH3493 pKa = 6.04LLLSYY3498 pKa = 9.92MAGQAIIEE3506 pKa = 4.47SPDD3509 pKa = 3.3TAFPEE3514 pKa = 4.37VPMRR3518 pKa = 11.84FANQVEE3524 pKa = 4.46MLQQLWGNSAGLSVIPVGVDD3544 pKa = 2.92KK3545 pKa = 11.19FFGSYY3550 pKa = 7.35EE3551 pKa = 4.08TEE3553 pKa = 3.64TWEE3556 pKa = 4.57GSISDD3561 pKa = 2.94IHH3563 pKa = 6.54YY3564 pKa = 9.87KK3565 pKa = 10.5RR3566 pKa = 11.84KK3567 pKa = 9.43FSKK3570 pKa = 10.1SRR3572 pKa = 11.84PRR3574 pKa = 11.84VLVCGWGTSGEE3585 pKa = 4.4FNVGMTYY3592 pKa = 10.62CKK3594 pKa = 10.28ALKK3597 pKa = 10.14EE3598 pKa = 4.07LGLVPILLTNCDD3610 pKa = 3.33QVSRR3614 pKa = 11.84IPEE3617 pKa = 3.9WVEE3620 pKa = 3.55YY3621 pKa = 10.16SCVPITSRR3629 pKa = 11.84VCTVLQLEE3637 pKa = 4.48SLRR3640 pKa = 11.84LDD3642 pKa = 3.5TMDD3645 pKa = 3.66NKK3647 pKa = 11.41AMVDD3651 pKa = 3.47QLKK3654 pKa = 9.6TYY3656 pKa = 10.34AAYY3659 pKa = 10.42DD3660 pKa = 3.97LLHH3663 pKa = 6.44SRR3665 pKa = 11.84PIKK3668 pKa = 10.34LIAVIGQEE3676 pKa = 3.96WFHH3679 pKa = 5.91TASIIAKK3686 pKa = 9.52AYY3688 pKa = 7.42NARR3691 pKa = 11.84MLYY3694 pKa = 10.44LSPHH3698 pKa = 7.13PYY3700 pKa = 9.81NLKK3703 pKa = 10.46NSPRR3707 pKa = 11.84PNGKK3711 pKa = 9.27PIDD3714 pKa = 4.19SKK3716 pKa = 11.03IHH3718 pKa = 5.46NASMAPGGKK3727 pKa = 8.06WKK3729 pKa = 10.63LYY3731 pKa = 9.59FGPGKK3736 pKa = 10.25ALEE3739 pKa = 4.32RR3740 pKa = 11.84MGFDD3744 pKa = 3.52PNLCVLEE3751 pKa = 4.8CEE3753 pKa = 4.62PSDD3756 pKa = 3.44TDD3758 pKa = 4.62VIISMHH3764 pKa = 6.89PDD3766 pKa = 3.88FVAGLVKK3773 pKa = 10.23EE3774 pKa = 4.34DD3775 pKa = 3.48EE3776 pKa = 4.34PRR3778 pKa = 11.84RR3779 pKa = 11.84HH3780 pKa = 5.19YY3781 pKa = 10.62VGHH3784 pKa = 6.85IGSTTWPDD3792 pKa = 3.34NEE3794 pKa = 4.91DD3795 pKa = 3.41PSLSKK3800 pKa = 10.85FILSNRR3806 pKa = 11.84NNICLVTASSCGSEE3820 pKa = 3.97STLNPFLTAIMYY3832 pKa = 8.2LVNNAHH3838 pKa = 5.83YY3839 pKa = 10.06VVVSGSFIKK3848 pKa = 9.72TLHH3851 pKa = 6.27PKK3853 pKa = 9.81SIKK3856 pKa = 10.5VGGKK3860 pKa = 7.86MVEE3863 pKa = 4.29LKK3865 pKa = 10.49PGQCHH3870 pKa = 5.31KK3871 pKa = 10.93QVFCTPALDD3880 pKa = 3.7LPRR3883 pKa = 11.84WAGYY3887 pKa = 10.4LYY3889 pKa = 10.82LAVHH3893 pKa = 6.73HH3894 pKa = 6.81GGTGTMLEE3902 pKa = 4.54CIRR3905 pKa = 11.84GKK3907 pKa = 10.02VPCLSWPIAFDD3918 pKa = 3.18QYY3920 pKa = 11.55LNARR3924 pKa = 11.84MTEE3927 pKa = 4.0YY3928 pKa = 10.62HH3929 pKa = 6.18QLTVGPCTPEE3939 pKa = 3.65EE3940 pKa = 4.06QEE3942 pKa = 4.98RR3943 pKa = 11.84GIQVYY3948 pKa = 10.66LDD3950 pKa = 3.15EE3951 pKa = 4.96LLRR3954 pKa = 11.84KK3955 pKa = 9.47RR3956 pKa = 11.84RR3957 pKa = 11.84AIKK3960 pKa = 9.77MNLEE3964 pKa = 4.08GMHH3967 pKa = 6.47HH3968 pKa = 6.78VGRR3971 pKa = 11.84CNSAVLTEE3979 pKa = 4.28TLAGLLNVFRR3989 pKa = 11.84NQPMWTHH3996 pKa = 6.42HH3997 pKa = 6.49SGHH4000 pKa = 6.72DD4001 pKa = 3.36VGVGLRR4007 pKa = 11.84GGAVMLPIGNFIDD4020 pKa = 4.15LASGVYY4026 pKa = 7.88TVKK4029 pKa = 11.02LEE4031 pKa = 4.38LEE4033 pKa = 4.48TEE4035 pKa = 4.22YY4036 pKa = 11.03SPPGIGYY4043 pKa = 7.47CTWNCYY4049 pKa = 7.46NRR4051 pKa = 11.84YY4052 pKa = 7.16MQNVCCNWEE4061 pKa = 4.11LLEE4064 pKa = 4.22PRR4066 pKa = 11.84YY4067 pKa = 10.16SDD4069 pKa = 3.82EE4070 pKa = 3.88YY4071 pKa = 10.86RR4072 pKa = 11.84KK4073 pKa = 9.9QSLSTVEE4080 pKa = 4.19VIKK4083 pKa = 11.08LGVQLGINVILSDD4096 pKa = 3.96INSKK4100 pKa = 9.06TSIYY4104 pKa = 10.63YY4105 pKa = 10.35HH4106 pKa = 7.0LFPGNNTIHH4115 pKa = 7.06LGLEE4119 pKa = 3.91NQTLMKK4125 pKa = 10.37HH4126 pKa = 6.3CILLKK4131 pKa = 10.81VPIEE4135 pKa = 4.05PPEE4138 pKa = 4.23LGSRR4142 pKa = 11.84VEE4144 pKa = 4.89LSQQKK4149 pKa = 9.34EE4150 pKa = 4.43NNWNIAITGLIEE4162 pKa = 3.95TGKK4165 pKa = 9.69IRR4167 pKa = 11.84CSRR4170 pKa = 11.84EE4171 pKa = 3.72QVNSAMEE4178 pKa = 4.24CVRR4181 pKa = 11.84DD4182 pKa = 4.2DD4183 pKa = 3.95MEE4185 pKa = 6.42ACFTDD4190 pKa = 3.69SNNLITRR4197 pKa = 11.84AALIQLHH4204 pKa = 6.99HH4205 pKa = 7.74IMEE4208 pKa = 4.37VQKK4211 pKa = 11.3NPILVDD4217 pKa = 3.67DD4218 pKa = 5.19FAFSTDD4224 pKa = 3.3GSASCAGRR4232 pKa = 11.84YY4233 pKa = 7.19SQWHH4237 pKa = 4.96NTLVLSPCIGGWGVGVCLYY4256 pKa = 10.8HH4257 pKa = 7.28SGRR4260 pKa = 11.84LTIKK4264 pKa = 10.65LFDD4267 pKa = 3.65GHH4269 pKa = 7.92IMTSGVALSLRR4280 pKa = 11.84ASCFKK4285 pKa = 10.69LYY4287 pKa = 9.79EE4288 pKa = 4.17ARR4290 pKa = 11.84CQVTITQQGEE4300 pKa = 3.94LLLALNQQTMKK4311 pKa = 10.0YY4312 pKa = 5.54TTSEE4316 pKa = 4.32VNCVKK4321 pKa = 10.46PSRR4324 pKa = 11.84VVGAQDD4330 pKa = 3.87DD4331 pKa = 4.49DD4332 pKa = 4.57YY4333 pKa = 11.78SLVIRR4338 pKa = 11.84HH4339 pKa = 5.45YY4340 pKa = 11.19DD4341 pKa = 3.25NRR4343 pKa = 11.84KK4344 pKa = 7.48HH4345 pKa = 6.27HH4346 pKa = 7.01LYY4348 pKa = 10.88DD4349 pKa = 3.37EE4350 pKa = 4.45ASYY4353 pKa = 10.77IEE4355 pKa = 4.31RR4356 pKa = 11.84AVSVRR4361 pKa = 11.84WLGEE4365 pKa = 4.17PINEE4369 pKa = 4.37TKK4371 pKa = 10.49FCDD4374 pKa = 3.22MTRR4377 pKa = 11.84SHH4379 pKa = 6.2NRR4381 pKa = 11.84AVDD4384 pKa = 3.52RR4385 pKa = 11.84VIYY4388 pKa = 10.48DD4389 pKa = 3.31HH4390 pKa = 6.82GQLLRR4395 pKa = 11.84CMEE4398 pKa = 4.38SSNKK4402 pKa = 9.09FWLLAAAGALVEE4414 pKa = 4.87RR4415 pKa = 11.84GQSYY4419 pKa = 10.64KK4420 pKa = 10.35IVGTSIVYY4428 pKa = 8.95RR4429 pKa = 11.84CKK4431 pKa = 10.44FRR4433 pKa = 11.84EE4434 pKa = 4.11SNIFDD4439 pKa = 3.5VMKK4442 pKa = 10.41KK4443 pKa = 7.69YY4444 pKa = 9.32TYY4446 pKa = 10.8NWLDD4450 pKa = 3.42EE4451 pKa = 4.55DD4452 pKa = 4.99ASDD4455 pKa = 4.7NKK4457 pKa = 10.36IATPLKK4463 pKa = 9.89WDD4465 pKa = 3.48VRR4467 pKa = 11.84WPLKK4471 pKa = 10.79NSDD4474 pKa = 3.37VASIFFIDD4482 pKa = 5.56LPTATAWITYY4492 pKa = 7.25LTGGRR4497 pKa = 11.84ADD4499 pKa = 3.59EE4500 pKa = 4.26VRR4502 pKa = 11.84LAEE4505 pKa = 5.01AIITTPVPACEE4516 pKa = 4.39IRR4518 pKa = 11.84TADD4521 pKa = 5.77DD4522 pKa = 3.45RR4523 pKa = 11.84DD4524 pKa = 3.55GWLLTHH4530 pKa = 7.24AAGSPALLTLRR4541 pKa = 11.84YY4542 pKa = 9.72GCYY4545 pKa = 9.79LVEE4548 pKa = 4.6AMAGGDD4554 pKa = 3.73TTGGSYY4560 pKa = 10.36SGAVWQEE4567 pKa = 3.81MKK4569 pKa = 10.71SNKK4572 pKa = 9.14HH4573 pKa = 5.34VSGDD4577 pKa = 3.07WFHH4580 pKa = 7.17IKK4582 pKa = 9.38PANEE4586 pKa = 3.99ADD4588 pKa = 3.65PKK4590 pKa = 10.0HH4591 pKa = 6.54RR4592 pKa = 11.84KK4593 pKa = 8.22AARR4596 pKa = 11.84EE4597 pKa = 3.94VAKK4600 pKa = 9.5LTTAMMMLEE4609 pKa = 4.15IEE4611 pKa = 4.4SLEE4614 pKa = 4.46HH4615 pKa = 5.65YY4616 pKa = 6.56TTTSISGVYY4625 pKa = 9.08EE4626 pKa = 3.95PEE4628 pKa = 3.71YY4629 pKa = 10.64LKK4631 pKa = 10.98YY4632 pKa = 10.05IEE4634 pKa = 4.83PMHH4637 pKa = 7.18DD4638 pKa = 2.72IGFLSEE4644 pKa = 4.78LEE4646 pKa = 4.14PLADD4650 pKa = 3.74YY4651 pKa = 9.61TPLHH4655 pKa = 6.02VLKK4658 pKa = 10.74LWDD4661 pKa = 4.04IEE4663 pKa = 4.34NDD4665 pKa = 3.37LTDD4668 pKa = 3.36WLQIYY4673 pKa = 10.04APQNVGSFITKK4684 pKa = 8.87EE4685 pKa = 3.73KK4686 pKa = 8.52PQRR4689 pKa = 11.84LIEE4692 pKa = 4.22CQKK4695 pKa = 8.16TTLTRR4700 pKa = 11.84YY4701 pKa = 8.86PLLSRR4706 pKa = 11.84PVLTKK4711 pKa = 10.51VAFEE4715 pKa = 4.13EE4716 pKa = 4.43TRR4718 pKa = 11.84TVAGRR4723 pKa = 11.84MFSIQHH4729 pKa = 5.31IRR4731 pKa = 11.84KK4732 pKa = 8.32GTIPTAKK4739 pKa = 8.92MVNDD4743 pKa = 3.55ICRR4746 pKa = 11.84AYY4748 pKa = 10.31FRR4750 pKa = 11.84PDD4752 pKa = 2.81WQEE4755 pKa = 3.5LCNKK4759 pKa = 9.39FKK4761 pKa = 10.86ADD4763 pKa = 4.3PIVYY4767 pKa = 10.01DD4768 pKa = 3.87PASIEE4773 pKa = 3.75NWIMEE4778 pKa = 4.35RR4779 pKa = 11.84KK4780 pKa = 8.89GAPEE4784 pKa = 4.06IIKK4787 pKa = 10.54EE4788 pKa = 4.3LMTKK4792 pKa = 10.55LAGEE4796 pKa = 4.76LMTKK4800 pKa = 10.13PISDD4804 pKa = 3.79VNIHH4808 pKa = 6.62LKK4810 pKa = 10.82LEE4812 pKa = 4.32SLLKK4816 pKa = 10.32EE4817 pKa = 4.18SPIVSWKK4824 pKa = 8.62QQQSRR4829 pKa = 11.84PIVWQPKK4836 pKa = 8.74AIAAIFSAVFIKK4848 pKa = 10.85AKK4850 pKa = 10.56DD4851 pKa = 3.5RR4852 pKa = 11.84LKK4854 pKa = 10.97EE4855 pKa = 3.86LLSDD4859 pKa = 3.48KK4860 pKa = 10.71VVYY4863 pKa = 10.83ADD4865 pKa = 3.21GHH4867 pKa = 5.79TPASLSARR4875 pKa = 11.84VRR4877 pKa = 11.84NVKK4880 pKa = 7.85GTKK4883 pKa = 8.28WFYY4886 pKa = 11.41EE4887 pKa = 3.9NDD4889 pKa = 3.17LTKK4892 pKa = 10.18QDD4894 pKa = 3.52RR4895 pKa = 11.84QTDD4898 pKa = 3.8EE4899 pKa = 5.33EE4900 pKa = 4.17ILKK4903 pKa = 10.53VEE4905 pKa = 3.83MAMYY4909 pKa = 9.91EE4910 pKa = 4.04LLGVHH4915 pKa = 6.76PLVISAWYY4923 pKa = 9.3SVHH4926 pKa = 6.26RR4927 pKa = 11.84HH4928 pKa = 3.95WRR4930 pKa = 11.84MKK4932 pKa = 9.1GTYY4935 pKa = 7.97TRR4937 pKa = 11.84SKK4939 pKa = 10.1RR4940 pKa = 11.84DD4941 pKa = 3.61FMRR4944 pKa = 11.84MTGQATTALGNVITNFQVHH4963 pKa = 5.83CRR4965 pKa = 11.84FVLRR4969 pKa = 11.84NQHH4972 pKa = 6.73RR4973 pKa = 11.84ILFMLFLGDD4982 pKa = 3.81DD4983 pKa = 3.29MLMFFSEE4990 pKa = 4.38KK4991 pKa = 10.15PDD4993 pKa = 3.21IKK4995 pKa = 10.85GLRR4998 pKa = 11.84NEE5000 pKa = 3.71IAVYY5004 pKa = 10.56FNMQSKK5010 pKa = 10.92DD5011 pKa = 4.08SINEE5015 pKa = 3.96LYY5017 pKa = 9.48GTFCGMLAYY5026 pKa = 8.16HH5027 pKa = 6.48TSEE5030 pKa = 4.46TTCEE5034 pKa = 3.94LGPDD5038 pKa = 4.19FMRR5041 pKa = 11.84LKK5043 pKa = 10.92YY5044 pKa = 10.33RR5045 pKa = 11.84FEE5047 pKa = 4.23VTNGVHH5053 pKa = 6.77EE5054 pKa = 5.14DD5055 pKa = 3.11SDD5057 pKa = 4.69LNMRR5061 pKa = 11.84MRR5063 pKa = 11.84TMSYY5067 pKa = 11.08CMMLGDD5073 pKa = 3.65ISEE5076 pKa = 4.21VRR5078 pKa = 11.84HH5079 pKa = 5.98VIDD5082 pKa = 3.67STGLPIQPVSWYY5094 pKa = 9.8SKK5096 pKa = 8.1PHH5098 pKa = 5.7AMQAAAHH5105 pKa = 6.18KK5106 pKa = 10.05HH5107 pKa = 5.07NSTPIQIGGVLHH5119 pKa = 6.46SLCQMMKK5126 pKa = 10.16DD5127 pKa = 2.82AKK5129 pKa = 9.93TFHH5132 pKa = 6.21TTFKK5136 pKa = 9.96MYY5138 pKa = 9.68TSKK5141 pKa = 10.65PRR5143 pKa = 11.84WW5144 pKa = 3.24

Molecular weight: 577.36 kDa
Isoelectric point according different methods:

Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try ESI

ChTry ESI

ArgC ESI

LysN ESI

TryLysC ESI

Try MALDI

ChTry MALDI

ArgC MALDI

LysN MALDI

TryLysC MALDI

Try LTQ

ChTry LTQ

ArgC LTQ

LysN LTQ

TryLysC LTQ

Try MSlow

ChTry MSlow

ArgC MSlow

LysN MSlow

TryLysC MSlow

Try MShigh

ChTry MShigh

ArgC MShigh

LysN MShigh

TryLysC MShigh

General Statistics

Number of major isoforms	Number of additional isoforms	Number of all proteins	Number of amino acids	Min. Seq. Length	Max. Seq. Length	Avg. Seq. Length	Avg. Mol. Weight
1	0	1	5144	5144	5144	5144.0	577.36

Amino acid frequency

Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu
5.793 ± 0.0	2.216 ± 0.0	5.851 ± 0.0	5.715 ± 0.0	2.449 ± 0.0	5.871 ± 0.0	3.499 ± 0.0	6.221 ± 0.0	5.851 ± 0.0	9.409 ± 0.0

Met	Asn	Gln	Pro	Arg	Ser	Thr	Val	Trp	Tyr
2.897 ± 0.0	4.899 ± 0.0	5.171 ± 0.0	3.285 ± 0.0	4.51 ± 0.0	7.018 ± 0.0	7.135 ± 0.0	7.018 ± 0.0	1.575 ± 0.0	3.616 ± 0.0

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here

See this proteome in:

Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski