Amino acid dipepetide frequency for Thrips palmi (Melon thrips)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.092AlaAla: 9.092 ± 0.062
1.322AlaCys: 1.322 ± 0.019
3.935AlaAsp: 3.935 ± 0.021
4.883AlaGlu: 4.883 ± 0.035
2.374AlaPhe: 2.374 ± 0.017
4.964AlaGly: 4.964 ± 0.031
1.822AlaHis: 1.822 ± 0.016
2.777AlaIle: 2.777 ± 0.018
3.77AlaLys: 3.77 ± 0.031
7.355AlaLeu: 7.355 ± 0.042
1.869AlaMet: 1.869 ± 0.014
2.667AlaAsn: 2.667 ± 0.018
5.075AlaPro: 5.075 ± 0.052
3.259AlaGln: 3.259 ± 0.03
4.177AlaArg: 4.177 ± 0.022
6.802AlaSer: 6.802 ± 0.032
4.378AlaThr: 4.378 ± 0.024
5.801AlaVal: 5.801 ± 0.032
0.752AlaTrp: 0.752 ± 0.009
1.625AlaTyr: 1.625 ± 0.015
0.001AlaXaa: 0.001 ± 0.0
Cys
1.276CysAla: 1.276 ± 0.013
0.463CysCys: 0.463 ± 0.007
1.131CysAsp: 1.131 ± 0.015
1.087CysGlu: 1.087 ± 0.012
0.683CysPhe: 0.683 ± 0.008
1.493CysGly: 1.493 ± 0.023
0.527CysHis: 0.527 ± 0.008
0.818CysIle: 0.818 ± 0.011
0.99CysLys: 0.99 ± 0.013
1.792CysLeu: 1.792 ± 0.018
0.382CysMet: 0.382 ± 0.006
0.804CysAsn: 0.804 ± 0.009
1.138CysPro: 1.138 ± 0.022
0.778CysGln: 0.778 ± 0.012
1.201CysArg: 1.201 ± 0.024
1.716CysSer: 1.716 ± 0.02
1.019CysThr: 1.019 ± 0.012
1.322CysVal: 1.322 ± 0.018
0.207CysTrp: 0.207 ± 0.004
0.462CysTyr: 0.462 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
4.208AspAla: 4.208 ± 0.026
1.064AspCys: 1.064 ± 0.015
4.116AspAsp: 4.116 ± 0.028
4.166AspGlu: 4.166 ± 0.027
2.011AspPhe: 2.011 ± 0.016
3.775AspGly: 3.775 ± 0.029
1.219AspHis: 1.219 ± 0.013
2.532AspIle: 2.532 ± 0.018
2.946AspLys: 2.946 ± 0.021
5.193AspLeu: 5.193 ± 0.025
1.325AspMet: 1.325 ± 0.01
2.057AspAsn: 2.057 ± 0.018
2.838AspPro: 2.838 ± 0.022
1.858AspGln: 1.858 ± 0.014
2.932AspArg: 2.932 ± 0.025
4.632AspSer: 4.632 ± 0.021
2.604AspThr: 2.604 ± 0.017
3.831AspVal: 3.831 ± 0.021
0.662AspTrp: 0.662 ± 0.009
1.427AspTyr: 1.427 ± 0.012
0.001AspXaa: 0.001 ± 0.0
Glu
5.227GluAla: 5.227 ± 0.046
1.266GluCys: 1.266 ± 0.021
4.436GluAsp: 4.436 ± 0.026
6.251GluGlu: 6.251 ± 0.058
1.838GluPhe: 1.838 ± 0.013
3.456GluGly: 3.456 ± 0.021
1.491GluHis: 1.491 ± 0.013
2.631GluIle: 2.631 ± 0.022
4.373GluLys: 4.373 ± 0.043
5.65GluLeu: 5.65 ± 0.041
1.582GluMet: 1.582 ± 0.013
2.724GluAsn: 2.724 ± 0.019
2.846GluPro: 2.846 ± 0.034
2.733GluGln: 2.733 ± 0.024
4.111GluArg: 4.111 ± 0.034
4.486GluSer: 4.486 ± 0.029
3.291GluThr: 3.291 ± 0.033
4.17GluVal: 4.17 ± 0.028
0.667GluTrp: 0.667 ± 0.009
1.472GluTyr: 1.472 ± 0.011
0.001GluXaa: 0.001 ± 0.0
Phe
2.109PheAla: 2.109 ± 0.016
0.729PheCys: 0.729 ± 0.009
1.792PheAsp: 1.792 ± 0.013
1.938PheGlu: 1.938 ± 0.017
1.284PhePhe: 1.284 ± 0.014
2.195PheGly: 2.195 ± 0.018
0.927PheHis: 0.927 ± 0.009
1.53PheIle: 1.53 ± 0.015
1.729PheLys: 1.729 ± 0.013
3.264PheLeu: 3.264 ± 0.025
0.793PheMet: 0.793 ± 0.009
1.412PheAsn: 1.412 ± 0.011
1.707PhePro: 1.707 ± 0.014
1.399PheGln: 1.399 ± 0.011
1.862PheArg: 1.862 ± 0.014
2.854PheSer: 2.854 ± 0.018
1.797PheThr: 1.797 ± 0.015
2.277PheVal: 2.277 ± 0.017
0.406PheTrp: 0.406 ± 0.006
0.969PheTyr: 0.969 ± 0.01
0.001PheXaa: 0.001 ± 0.0
Gly
4.787GlyAla: 4.787 ± 0.029
1.11GlyCys: 1.11 ± 0.015
3.441GlyAsp: 3.441 ± 0.025
3.587GlyGlu: 3.587 ± 0.02
2.178GlyPhe: 2.178 ± 0.017
5.525GlyGly: 5.525 ± 0.061
1.886GlyHis: 1.886 ± 0.021
2.333GlyIle: 2.333 ± 0.017
3.262GlyLys: 3.262 ± 0.019
5.531GlyLeu: 5.531 ± 0.034
1.509GlyMet: 1.509 ± 0.017
2.386GlyAsn: 2.386 ± 0.019
3.862GlyPro: 3.862 ± 0.053
2.693GlyGln: 2.693 ± 0.026
3.787GlyArg: 3.787 ± 0.03
5.879GlySer: 5.879 ± 0.036
3.367GlyThr: 3.367 ± 0.023
4.132GlyVal: 4.132 ± 0.023
0.726GlyTrp: 0.726 ± 0.01
1.723GlyTyr: 1.723 ± 0.017
0.001GlyXaa: 0.001 ± 0.0
His
1.813HisAla: 1.813 ± 0.015
0.601HisCys: 0.601 ± 0.006
1.195HisAsp: 1.195 ± 0.011
1.334HisGlu: 1.334 ± 0.013
1.001HisPhe: 1.001 ± 0.009
1.782HisGly: 1.782 ± 0.021
1.239HisHis: 1.239 ± 0.02
1.146HisIle: 1.146 ± 0.011
1.225HisLys: 1.225 ± 0.011
2.769HisLeu: 2.769 ± 0.022
0.625HisMet: 0.625 ± 0.008
0.99HisAsn: 0.99 ± 0.01
1.708HisPro: 1.708 ± 0.023
1.365HisGln: 1.365 ± 0.016
1.654HisArg: 1.654 ± 0.014
2.271HisSer: 2.271 ± 0.02
1.413HisThr: 1.413 ± 0.017
1.605HisVal: 1.605 ± 0.013
0.323HisTrp: 0.323 ± 0.005
0.729HisTyr: 0.729 ± 0.007
0.0HisXaa: 0.0 ± 0.0
Ile
2.811IleAla: 2.811 ± 0.018
0.837IleCys: 0.837 ± 0.01
2.149IleAsp: 2.149 ± 0.018
2.43IleGlu: 2.43 ± 0.02
1.448IlePhe: 1.448 ± 0.014
2.191IleGly: 2.191 ± 0.018
1.104IleHis: 1.104 ± 0.012
1.898IleIle: 1.898 ± 0.015
2.344IleLys: 2.344 ± 0.015
3.783IleLeu: 3.783 ± 0.022
0.947IleMet: 0.947 ± 0.011
1.775IleAsn: 1.775 ± 0.014
2.298IlePro: 2.298 ± 0.017
1.832IleGln: 1.832 ± 0.015
2.221IleArg: 2.221 ± 0.013
3.266IleSer: 3.266 ± 0.022
2.224IleThr: 2.224 ± 0.017
2.707IleVal: 2.707 ± 0.019
0.385IleTrp: 0.385 ± 0.006
1.0IleTyr: 1.0 ± 0.009
0.0IleXaa: 0.0 ± 0.0
Lys
3.882LysAla: 3.882 ± 0.025
1.035LysCys: 1.035 ± 0.012
3.226LysAsp: 3.226 ± 0.02
4.226LysGlu: 4.226 ± 0.037
1.761LysPhe: 1.761 ± 0.013
2.853LysGly: 2.853 ± 0.019
1.318LysHis: 1.318 ± 0.013
2.296LysIle: 2.296 ± 0.017
4.625LysLys: 4.625 ± 0.044
4.904LysLeu: 4.904 ± 0.029
1.348LysMet: 1.348 ± 0.012
2.152LysAsn: 2.152 ± 0.016
3.163LysPro: 3.163 ± 0.05
2.389LysGln: 2.389 ± 0.017
3.441LysArg: 3.441 ± 0.022
3.961LysSer: 3.961 ± 0.027
2.926LysThr: 2.926 ± 0.019
3.433LysVal: 3.433 ± 0.02
0.545LysTrp: 0.545 ± 0.007
1.414LysTyr: 1.414 ± 0.012
0.001LysXaa: 0.001 ± 0.0
Leu
7.142LeuAla: 7.142 ± 0.036
1.805LeuCys: 1.805 ± 0.014
5.053LeuAsp: 5.053 ± 0.026
6.235LeuGlu: 6.235 ± 0.046
2.912LeuPhe: 2.912 ± 0.019
5.271LeuGly: 5.271 ± 0.026
2.653LeuHis: 2.653 ± 0.018
3.244LeuIle: 3.244 ± 0.019
5.319LeuLys: 5.319 ± 0.035
9.235LeuLeu: 9.235 ± 0.046
1.941LeuMet: 1.941 ± 0.016
3.586LeuAsn: 3.586 ± 0.021
5.422LeuPro: 5.422 ± 0.027
5.111LeuGln: 5.111 ± 0.035
6.169LeuArg: 6.169 ± 0.035
7.63LeuSer: 7.63 ± 0.032
4.692LeuThr: 4.692 ± 0.021
5.767LeuVal: 5.767 ± 0.027
1.004LeuTrp: 1.004 ± 0.01
2.15LeuTyr: 2.15 ± 0.017
0.001LeuXaa: 0.001 ± 0.0
Met
1.986MetAla: 1.986 ± 0.014
0.407MetCys: 0.407 ± 0.006
1.393MetAsp: 1.393 ± 0.011
1.616MetGlu: 1.616 ± 0.015
0.782MetPhe: 0.782 ± 0.009
1.463MetGly: 1.463 ± 0.02
0.544MetHis: 0.544 ± 0.007
0.792MetIle: 0.792 ± 0.009
1.323MetLys: 1.323 ± 0.011
2.008MetLeu: 2.008 ± 0.015
0.65MetMet: 0.65 ± 0.008
0.893MetAsn: 0.893 ± 0.011
1.342MetPro: 1.342 ± 0.015
1.076MetGln: 1.076 ± 0.013
1.247MetArg: 1.247 ± 0.011
1.901MetSer: 1.901 ± 0.013
1.205MetThr: 1.205 ± 0.01
1.417MetVal: 1.417 ± 0.014
0.269MetTrp: 0.269 ± 0.005
0.615MetTyr: 0.615 ± 0.008
0.0MetXaa: 0.0 ± 0.0
Asn
2.829AsnAla: 2.829 ± 0.017
0.754AsnCys: 0.754 ± 0.01
1.918AsnAsp: 1.918 ± 0.014
2.337AsnGlu: 2.337 ± 0.016
1.426AsnPhe: 1.426 ± 0.012
2.817AsnGly: 2.817 ± 0.023
1.024AsnHis: 1.024 ± 0.011
1.985AsnIle: 1.985 ± 0.016
2.171AsnLys: 2.171 ± 0.018
3.699AsnLeu: 3.699 ± 0.023
1.037AsnMet: 1.037 ± 0.014
2.104AsnAsn: 2.104 ± 0.018
2.095AsnPro: 2.095 ± 0.016
1.666AsnGln: 1.666 ± 0.015
1.928AsnArg: 1.928 ± 0.014
3.298AsnSer: 3.298 ± 0.022
1.986AsnThr: 1.986 ± 0.013
2.66AsnVal: 2.66 ± 0.017
0.411AsnTrp: 0.411 ± 0.007
1.088AsnTyr: 1.088 ± 0.012
0.0AsnXaa: 0.0 ± 0.0
Pro
5.358ProAla: 5.358 ± 0.044
0.933ProCys: 0.933 ± 0.023
3.084ProAsp: 3.084 ± 0.021
3.61ProGlu: 3.61 ± 0.041
1.82ProPhe: 1.82 ± 0.014
4.354ProGly: 4.354 ± 0.052
1.647ProHis: 1.647 ± 0.021
2.006ProIle: 2.006 ± 0.014
2.741ProLys: 2.741 ± 0.03
4.817ProLeu: 4.817 ± 0.026
1.24ProMet: 1.24 ± 0.015
2.201ProAsn: 2.201 ± 0.02
5.965ProPro: 5.965 ± 0.068
2.884ProGln: 2.884 ± 0.031
3.238ProArg: 3.238 ± 0.026
6.121ProSer: 6.121 ± 0.047
3.68ProThr: 3.68 ± 0.045
4.07ProVal: 4.07 ± 0.031
0.585ProTrp: 0.585 ± 0.009
1.413ProTyr: 1.413 ± 0.014
0.002ProXaa: 0.002 ± 0.0
Gln
3.528GlnAla: 3.528 ± 0.03
0.838GlnCys: 0.838 ± 0.013
2.278GlnAsp: 2.278 ± 0.017
2.952GlnGlu: 2.952 ± 0.023
1.291GlnPhe: 1.291 ± 0.011
2.823GlnGly: 2.823 ± 0.03
1.438GlnHis: 1.438 ± 0.016
1.685GlnIle: 1.685 ± 0.014
2.212GlnLys: 2.212 ± 0.017
4.39GlnLeu: 4.39 ± 0.032
1.117GlnMet: 1.117 ± 0.016
1.657GlnAsn: 1.657 ± 0.016
2.832GlnPro: 2.832 ± 0.029
4.313GlnGln: 4.313 ± 0.097
2.912GlnArg: 2.912 ± 0.021
3.3GlnSer: 3.3 ± 0.024
2.216GlnThr: 2.216 ± 0.016
2.778GlnVal: 2.778 ± 0.019
0.497GlnTrp: 0.497 ± 0.007
1.129GlnTyr: 1.129 ± 0.012
0.001GlnXaa: 0.001 ± 0.0
Arg
4.195ArgAla: 4.195 ± 0.026
1.153ArgCys: 1.153 ± 0.017
3.312ArgAsp: 3.312 ± 0.027
3.824ArgGlu: 3.824 ± 0.025
1.904ArgPhe: 1.904 ± 0.013
3.601ArgGly: 3.601 ± 0.032
1.718ArgHis: 1.718 ± 0.013
2.333ArgIle: 2.333 ± 0.016
3.559ArgLys: 3.559 ± 0.026
5.501ArgLeu: 5.501 ± 0.033
1.246ArgMet: 1.246 ± 0.01
2.288ArgAsn: 2.288 ± 0.016
3.404ArgPro: 3.404 ± 0.025
2.664ArgGln: 2.664 ± 0.017
4.866ArgArg: 4.866 ± 0.033
4.831ArgSer: 4.831 ± 0.036
2.949ArgThr: 2.949 ± 0.017
3.514ArgVal: 3.514 ± 0.018
0.703ArgTrp: 0.703 ± 0.008
1.396ArgTyr: 1.396 ± 0.011
0.001ArgXaa: 0.001 ± 0.0
Ser
6.399SerAla: 6.399 ± 0.037
1.542SerCys: 1.542 ± 0.021
4.633SerAsp: 4.633 ± 0.025
4.802SerGlu: 4.802 ± 0.028
2.699SerPhe: 2.699 ± 0.018
5.848SerGly: 5.848 ± 0.034
2.128SerHis: 2.128 ± 0.018
3.203SerIle: 3.203 ± 0.02
4.324SerLys: 4.324 ± 0.028
7.655SerLeu: 7.655 ± 0.033
1.831SerMet: 1.831 ± 0.014
3.375SerAsn: 3.375 ± 0.023
6.05SerPro: 6.05 ± 0.046
3.634SerGln: 3.634 ± 0.023
4.679SerArg: 4.679 ± 0.028
10.458SerSer: 10.458 ± 0.079
5.203SerThr: 5.203 ± 0.038
5.381SerVal: 5.381 ± 0.027
0.902SerTrp: 0.902 ± 0.009
1.88SerTyr: 1.88 ± 0.018
0.001SerXaa: 0.001 ± 0.0
Thr
4.45ThrAla: 4.45 ± 0.026
1.062ThrCys: 1.062 ± 0.016
2.649ThrAsp: 2.649 ± 0.02
3.188ThrGlu: 3.188 ± 0.033
1.829ThrPhe: 1.829 ± 0.015
3.348ThrGly: 3.348 ± 0.02
1.37ThrHis: 1.37 ± 0.015
2.245ThrIle: 2.245 ± 0.016
2.536ThrLys: 2.536 ± 0.017
5.029ThrLeu: 5.029 ± 0.026
1.166ThrMet: 1.166 ± 0.011
2.012ThrAsn: 2.012 ± 0.013
4.18ThrPro: 4.18 ± 0.035
2.041ThrGln: 2.041 ± 0.017
2.581ThrArg: 2.581 ± 0.018
5.159ThrSer: 5.159 ± 0.034
3.867ThrThr: 3.867 ± 0.061
3.935ThrVal: 3.935 ± 0.027
0.587ThrTrp: 0.587 ± 0.007
1.292ThrTyr: 1.292 ± 0.011
0.001ThrXaa: 0.001 ± 0.0
Val
5.335ValAla: 5.335 ± 0.027
1.535ValCys: 1.535 ± 0.018
3.667ValAsp: 3.667 ± 0.019
4.149ValGlu: 4.149 ± 0.028
2.247ValPhe: 2.247 ± 0.015
3.641ValGly: 3.641 ± 0.023
1.693ValHis: 1.693 ± 0.014
2.649ValIle: 2.649 ± 0.017
3.57ValLys: 3.57 ± 0.021
6.359ValLeu: 6.359 ± 0.029
1.426ValMet: 1.426 ± 0.012
2.564ValAsn: 2.564 ± 0.016
4.093ValPro: 4.093 ± 0.029
2.93ValGln: 2.93 ± 0.021
3.689ValArg: 3.689 ± 0.022
5.267ValSer: 5.267 ± 0.023
3.821ValThr: 3.821 ± 0.026
4.921ValVal: 4.921 ± 0.027
0.744ValTrp: 0.744 ± 0.009
1.622ValTyr: 1.622 ± 0.013
0.001ValXaa: 0.001 ± 0.0
Trp
0.679TrpAla: 0.679 ± 0.008
0.256TrpCys: 0.256 ± 0.005
0.631TrpAsp: 0.631 ± 0.008
0.658TrpGlu: 0.658 ± 0.007
0.412TrpPhe: 0.412 ± 0.008
0.626TrpGly: 0.626 ± 0.01
0.284TrpHis: 0.284 ± 0.005
0.459TrpIle: 0.459 ± 0.008
0.636TrpLys: 0.636 ± 0.008
1.114TrpLeu: 1.114 ± 0.013
0.301TrpMet: 0.301 ± 0.005
0.505TrpAsn: 0.505 ± 0.007
0.482TrpPro: 0.482 ± 0.008
0.465TrpGln: 0.465 ± 0.006
0.773TrpArg: 0.773 ± 0.008
0.84TrpSer: 0.84 ± 0.009
0.623TrpThr: 0.623 ± 0.009
0.654TrpVal: 0.654 ± 0.007
0.182TrpTrp: 0.182 ± 0.004
0.283TrpTyr: 0.283 ± 0.005
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.593TyrAla: 1.593 ± 0.014
0.575TyrCys: 0.575 ± 0.008
1.355TyrAsp: 1.355 ± 0.013
1.429TyrGlu: 1.429 ± 0.012
1.073TyrPhe: 1.073 ± 0.012
1.679TyrGly: 1.679 ± 0.017
0.754TyrHis: 0.754 ± 0.008
1.088TyrIle: 1.088 ± 0.009
1.245TyrLys: 1.245 ± 0.011
2.294TyrLeu: 2.294 ± 0.017
0.594TyrMet: 0.594 ± 0.007
1.08TyrAsn: 1.08 ± 0.012
1.267TyrPro: 1.267 ± 0.013
1.095TyrGln: 1.095 ± 0.012
1.492TyrArg: 1.492 ± 0.013
1.956TyrSer: 1.956 ± 0.016
1.265TyrThr: 1.265 ± 0.013
1.546TyrVal: 1.546 ± 0.013
0.308TyrTrp: 0.308 ± 0.005
0.83TyrTyr: 0.83 ± 0.009
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.001XaaAla: 0.001 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.001XaaGlu: 0.001 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.001XaaGly: 0.001 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.001XaaLys: 0.001 ± 0.0
0.001XaaLeu: 0.001 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.001XaaPro: 0.001 ± 0.0
0.001XaaGln: 0.001 ± 0.0
0.001XaaArg: 0.001 ± 0.0
0.001XaaSer: 0.001 ± 0.0
0.001XaaThr: 0.001 ± 0.0
0.001XaaVal: 0.001 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 20971 proteins (13368287 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski