Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)

Taxonomy: Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes; Rowavirales; Adenoviridae; Mastadenovirus; Human mastadenovirus C

Average proteome isoelectric point is 7.12

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 47 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P03254-3|E1A-3_ADE02 Isoform of P03254 Isoform early E1A 6 kDa protein of Early E1A protein OS=Human adenovirus C serotype 2 OX=10515 PE=1 SV=1
MM1 pKa = 7.5RR2 pKa = 11.84HH3 pKa = 6.51IICHH7 pKa = 5.93GGVITEE13 pKa = 4.22EE14 pKa = 4.15MAASLLDD21 pKa = 3.6QLIEE25 pKa = 4.19EE26 pKa = 4.48VLADD30 pKa = 3.85NLPPPSHH37 pKa = 7.16FEE39 pKa = 3.8PPTLHH44 pKa = 6.78EE45 pKa = 5.5LYY47 pKa = 10.58DD48 pKa = 4.45LDD50 pKa = 3.62VTAPEE55 pKa = 4.89DD56 pKa = 3.83PNEE59 pKa = 4.13EE60 pKa = 3.85AVSQIFPDD68 pKa = 3.76SVMLAVQEE76 pKa = 5.07GIDD79 pKa = 4.38LLTFPPAPGSPEE91 pKa = 3.95PPHH94 pKa = 7.1LSRR97 pKa = 11.84QPEE100 pKa = 4.1QPEE103 pKa = 3.86QRR105 pKa = 11.84ALGPVSMPNLVPEE118 pKa = 4.78VIDD121 pKa = 3.89LTCHH125 pKa = 5.71EE126 pKa = 5.16AGFPPSDD133 pKa = 4.54DD134 pKa = 3.73EE135 pKa = 5.56DD136 pKa = 4.3EE137 pKa = 4.68EE138 pKa = 5.74GPVSEE143 pKa = 5.29PEE145 pKa = 4.22PEE147 pKa = 4.37PEE149 pKa = 4.57PEE151 pKa = 4.34PEE153 pKa = 3.76PARR156 pKa = 11.84PTRR159 pKa = 11.84RR160 pKa = 11.84PKK162 pKa = 10.32LVPAILRR169 pKa = 11.84RR170 pKa = 11.84PTSPVSRR177 pKa = 11.84EE178 pKa = 4.32CNSSTDD184 pKa = 3.44SCDD187 pKa = 3.3SGPSNTPPEE196 pKa = 4.07IHH198 pKa = 6.71PVVPLCPIKK207 pKa = 10.4PVAVRR212 pKa = 11.84VGGRR216 pKa = 11.84RR217 pKa = 11.84QAVEE221 pKa = 4.48CIEE224 pKa = 4.76DD225 pKa = 3.84LLNEE229 pKa = 4.41SGQPLDD235 pKa = 4.51LSCKK239 pKa = 10.03RR240 pKa = 11.84PRR242 pKa = 11.84PP243 pKa = 3.69

Molecular weight: 26.45 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P15133|E3RDA_ADE02 Pre-early 3 receptor internalization and degradation alpha protein OS=Human adenovirus C serotype 2 OX=10515 PE=1 SV=1
MM1 pKa = 7.77ALTCRR6 pKa = 11.84LRR8 pKa = 11.84FPVPGFRR15 pKa = 11.84GRR17 pKa = 11.84MHH19 pKa = 7.55RR20 pKa = 11.84RR21 pKa = 11.84RR22 pKa = 11.84GMAGHH27 pKa = 7.2GLTGGMRR34 pKa = 11.84RR35 pKa = 11.84AHH37 pKa = 5.79HH38 pKa = 5.82RR39 pKa = 11.84RR40 pKa = 11.84RR41 pKa = 11.84RR42 pKa = 11.84ASHH45 pKa = 5.58RR46 pKa = 11.84RR47 pKa = 11.84MRR49 pKa = 11.84GGILPLLIPLIAAAIGAVPGIASVALQAQRR79 pKa = 11.84HH80 pKa = 4.41

Molecular weight: 8.85 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

45

2

47

13172

55

1198

280.3

31.22

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.518 ± 0.361

1.906 ± 0.225

4.866 ± 0.281

6.051 ± 0.418

3.356 ± 0.205

6.445 ± 0.29

2.353 ± 0.157

3.743 ± 0.196

3.477 ± 0.348

9.057 ± 0.367

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.467 ± 0.168

3.971 ± 0.431

7.653 ± 0.459

4.1 ± 0.223

8.381 ± 0.555

7.432 ± 0.481

5.975 ± 0.425

6.165 ± 0.274

1.283 ± 0.112

2.801 ± 0.29
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski