Amino acid dipepetide frequency for Jiella endophytica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.326AlaAla: 19.326 ± 0.196	1.054AlaCys: 1.054 ± 0.029	7.201AlaAsp: 7.201 ± 0.086	8.95AlaGlu: 8.95 ± 0.092	4.768AlaPhe: 4.768 ± 0.069	12.323AlaGly: 12.323 ± 0.128	1.932AlaHis: 1.932 ± 0.035	7.205AlaIle: 7.205 ± 0.075	4.215AlaLys: 4.215 ± 0.066	13.057AlaLeu: 13.057 ± 0.111	3.731AlaMet: 3.731 ± 0.055	2.723AlaAsn: 2.723 ± 0.06	5.61AlaPro: 5.61 ± 0.082	2.916AlaGln: 2.916 ± 0.057	8.849AlaArg: 8.849 ± 0.114	7.088AlaSer: 7.088 ± 0.089	6.184AlaThr: 6.184 ± 0.072	9.221AlaVal: 9.221 ± 0.094	1.309AlaTrp: 1.309 ± 0.032	2.578AlaTyr: 2.578 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.801CysAla: 0.801 ± 0.025	0.083CysCys: 0.083 ± 0.008	0.526CysAsp: 0.526 ± 0.019	0.47CysGlu: 0.47 ± 0.021	0.319CysPhe: 0.319 ± 0.015	0.961CysGly: 0.961 ± 0.028	0.241CysHis: 0.241 ± 0.015	0.341CysIle: 0.341 ± 0.016	0.159CysLys: 0.159 ± 0.011	0.862CysLeu: 0.862 ± 0.027	0.144CysMet: 0.144 ± 0.01	0.194CysAsn: 0.194 ± 0.011	0.436CysPro: 0.436 ± 0.021	0.206CysGln: 0.206 ± 0.013	0.705CysArg: 0.705 ± 0.029	0.425CysSer: 0.425 ± 0.018	0.317CysThr: 0.317 ± 0.015	0.527CysVal: 0.527 ± 0.018	0.104CysTrp: 0.104 ± 0.009	0.172CysTyr: 0.172 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.229AspAla: 7.229 ± 0.097	0.499AspCys: 0.499 ± 0.019	3.508AspAsp: 3.508 ± 0.066	3.881AspGlu: 3.881 ± 0.061	2.349AspPhe: 2.349 ± 0.04	5.821AspGly: 5.821 ± 0.103	1.305AspHis: 1.305 ± 0.032	2.886AspIle: 2.886 ± 0.05	1.729AspLys: 1.729 ± 0.038	6.104AspLeu: 6.104 ± 0.078	1.25AspMet: 1.25 ± 0.032	1.259AspAsn: 1.259 ± 0.035	3.649AspPro: 3.649 ± 0.044	1.608AspGln: 1.608 ± 0.032	4.55AspArg: 4.55 ± 0.066	2.036AspSer: 2.036 ± 0.038	2.557AspThr: 2.557 ± 0.067	4.156AspVal: 4.156 ± 0.061	0.899AspTrp: 0.899 ± 0.025	1.525AspTyr: 1.525 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	9.213GluAla: 9.213 ± 0.1	0.322GluCys: 0.322 ± 0.015	3.151GluAsp: 3.151 ± 0.049	3.669GluGlu: 3.669 ± 0.061	1.797GluPhe: 1.797 ± 0.037	4.671GluGly: 4.671 ± 0.068	1.053GluHis: 1.053 ± 0.029	3.955GluIle: 3.955 ± 0.051	2.551GluLys: 2.551 ± 0.049	5.061GluLeu: 5.061 ± 0.059	1.719GluMet: 1.719 ± 0.033	1.588GluAsn: 1.588 ± 0.035	3.154GluPro: 3.154 ± 0.049	1.646GluGln: 1.646 ± 0.036	5.474GluArg: 5.474 ± 0.078	2.495GluSer: 2.495 ± 0.047	4.336GluThr: 4.336 ± 0.058	3.846GluVal: 3.846 ± 0.055	0.705GluTrp: 0.705 ± 0.025	0.919GluTyr: 0.919 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	5.014PheAla: 5.014 ± 0.071	0.413PheCys: 0.413 ± 0.017	2.869PheAsp: 2.869 ± 0.048	2.364PheGlu: 2.364 ± 0.041	1.529PhePhe: 1.529 ± 0.037	3.834PheGly: 3.834 ± 0.062	0.733PheHis: 0.733 ± 0.024	1.521PheIle: 1.521 ± 0.04	0.865PheLys: 0.865 ± 0.027	3.614PheLeu: 3.614 ± 0.059	0.769PheMet: 0.769 ± 0.021	0.867PheAsn: 0.867 ± 0.026	1.614PhePro: 1.614 ± 0.034	1.045PheGln: 1.045 ± 0.027	2.357PheArg: 2.357 ± 0.043	2.417PheSer: 2.417 ± 0.039	1.849PheThr: 1.849 ± 0.038	3.212PheVal: 3.212 ± 0.049	0.515PheTrp: 0.515 ± 0.02	0.884PheTyr: 0.884 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	9.809GlyAla: 9.809 ± 0.115	0.868GlyCys: 0.868 ± 0.027	5.019GlyAsp: 5.019 ± 0.1	6.046GlyGlu: 6.046 ± 0.08	3.848GlyPhe: 3.848 ± 0.05	7.976GlyGly: 7.976 ± 0.116	1.897GlyHis: 1.897 ± 0.04	4.713GlyIle: 4.713 ± 0.063	3.186GlyLys: 3.186 ± 0.052	9.016GlyLeu: 9.016 ± 0.09	2.299GlyMet: 2.299 ± 0.041	2.086GlyAsn: 2.086 ± 0.068	3.762GlyPro: 3.762 ± 0.047	2.545GlyGln: 2.545 ± 0.043	6.923GlyArg: 6.923 ± 0.085	5.117GlySer: 5.117 ± 0.075	4.689GlyThr: 4.689 ± 0.067	6.012GlyVal: 6.012 ± 0.059	1.302GlyTrp: 1.302 ± 0.034	2.216GlyTyr: 2.216 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.065HisAla: 2.065 ± 0.038	0.23HisCys: 0.23 ± 0.014	1.134HisAsp: 1.134 ± 0.031	0.974HisGlu: 0.974 ± 0.028	0.829HisPhe: 0.829 ± 0.023	1.854HisGly: 1.854 ± 0.035	0.57HisHis: 0.57 ± 0.023	0.75HisIle: 0.75 ± 0.022	0.368HisLys: 0.368 ± 0.017	1.929HisLeu: 1.929 ± 0.043	0.445HisMet: 0.445 ± 0.018	0.37HisAsn: 0.37 ± 0.017	1.316HisPro: 1.316 ± 0.032	0.568HisGln: 0.568 ± 0.022	1.408HisArg: 1.408 ± 0.033	0.9HisSer: 0.9 ± 0.028	0.674HisThr: 0.674 ± 0.023	1.466HisVal: 1.466 ± 0.032	0.26HisTrp: 0.26 ± 0.014	0.498HisTyr: 0.498 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	7.86IleAla: 7.86 ± 0.105	0.461IleCys: 0.461 ± 0.017	3.788IleAsp: 3.788 ± 0.055	3.677IleGlu: 3.677 ± 0.065	1.775IlePhe: 1.775 ± 0.039	5.143IleGly: 5.143 ± 0.062	0.834IleHis: 0.834 ± 0.025	1.919IleIle: 1.919 ± 0.046	1.19IleLys: 1.19 ± 0.029	4.708IleLeu: 4.708 ± 0.07	0.835IleMet: 0.835 ± 0.027	1.144IleAsn: 1.144 ± 0.03	2.18IlePro: 2.18 ± 0.038	1.032IleGln: 1.032 ± 0.026	3.268IleArg: 3.268 ± 0.045	2.695IleSer: 2.695 ± 0.045	2.462IleThr: 2.462 ± 0.053	4.72IleVal: 4.72 ± 0.065	0.503IleTrp: 0.503 ± 0.019	1.035IleTyr: 1.035 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	4.456LysAla: 4.456 ± 0.068	0.138LysCys: 0.138 ± 0.011	1.848LysAsp: 1.848 ± 0.038	1.622LysGlu: 1.622 ± 0.037	0.827LysPhe: 0.827 ± 0.024	2.739LysGly: 2.739 ± 0.051	0.482LysHis: 0.482 ± 0.021	1.697LysIle: 1.697 ± 0.037	1.2LysLys: 1.2 ± 0.038	3.048LysLeu: 3.048 ± 0.054	0.723LysMet: 0.723 ± 0.022	0.79LysAsn: 0.79 ± 0.026	2.002LysPro: 2.002 ± 0.041	0.837LysGln: 0.837 ± 0.028	2.369LysArg: 2.369 ± 0.048	1.902LysSer: 1.902 ± 0.039	1.938LysThr: 1.938 ± 0.036	2.34LysVal: 2.34 ± 0.047	0.326LysTrp: 0.326 ± 0.017	0.515LysTyr: 0.515 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	14.2LeuAla: 14.2 ± 0.122	0.874LeuCys: 0.874 ± 0.026	6.073LeuAsp: 6.073 ± 0.084	5.008LeuGlu: 5.008 ± 0.064	3.762LeuPhe: 3.762 ± 0.059	8.349LeuGly: 8.349 ± 0.083	1.525LeuHis: 1.525 ± 0.035	4.688LeuIle: 4.688 ± 0.067	3.841LeuLys: 3.841 ± 0.06	8.751LeuLeu: 8.751 ± 0.114	2.202LeuMet: 2.202 ± 0.045	2.213LeuAsn: 2.213 ± 0.041	5.397LeuPro: 5.397 ± 0.073	2.417LeuGln: 2.417 ± 0.044	6.119LeuArg: 6.119 ± 0.086	6.794LeuSer: 6.794 ± 0.085	5.385LeuThr: 5.385 ± 0.064	7.859LeuVal: 7.859 ± 0.087	1.019LeuTrp: 1.019 ± 0.028	1.97LeuTyr: 1.97 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	3.156MetAla: 3.156 ± 0.053	0.119MetCys: 0.119 ± 0.009	1.066MetAsp: 1.066 ± 0.027	1.13MetGlu: 1.13 ± 0.029	0.663MetPhe: 0.663 ± 0.021	1.706MetGly: 1.706 ± 0.041	0.408MetHis: 0.408 ± 0.017	1.37MetIle: 1.37 ± 0.034	0.955MetLys: 0.955 ± 0.029	2.325MetLeu: 2.325 ± 0.036	0.664MetMet: 0.664 ± 0.022	0.705MetAsn: 0.705 ± 0.02	1.565MetPro: 1.565 ± 0.035	0.79MetGln: 0.79 ± 0.022	1.947MetArg: 1.947 ± 0.039	1.649MetSer: 1.649 ± 0.032	1.84MetThr: 1.84 ± 0.038	1.644MetVal: 1.644 ± 0.037	0.173MetTrp: 0.173 ± 0.009	0.281MetTyr: 0.281 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.977AsnAla: 2.977 ± 0.05	0.216AsnCys: 0.216 ± 0.013	1.317AsnAsp: 1.317 ± 0.045	1.188AsnGlu: 1.188 ± 0.027	0.89AsnPhe: 0.89 ± 0.025	2.319AsnGly: 2.319 ± 0.063	0.43AsnHis: 0.43 ± 0.019	1.108AsnIle: 1.108 ± 0.032	0.552AsnLys: 0.552 ± 0.022	2.342AsnLeu: 2.342 ± 0.048	0.518AsnMet: 0.518 ± 0.02	0.532AsnAsn: 0.532 ± 0.022	1.563AsnPro: 1.563 ± 0.033	0.682AsnGln: 0.682 ± 0.025	1.652AsnArg: 1.652 ± 0.032	1.083AsnSer: 1.083 ± 0.029	1.067AsnThr: 1.067 ± 0.029	1.852AsnVal: 1.852 ± 0.04	0.37AsnTrp: 0.37 ± 0.018	0.634AsnTyr: 0.634 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	6.737ProAla: 6.737 ± 0.086	0.293ProCys: 0.293 ± 0.015	3.652ProAsp: 3.652 ± 0.056	3.89ProGlu: 3.89 ± 0.063	2.073ProPhe: 2.073 ± 0.038	4.666ProGly: 4.666 ± 0.058	0.996ProHis: 0.996 ± 0.029	2.378ProIle: 2.378 ± 0.038	1.787ProLys: 1.787 ± 0.037	4.758ProLeu: 4.758 ± 0.065	1.162ProMet: 1.162 ± 0.029	1.218ProAsn: 1.218 ± 0.028	2.408ProPro: 2.408 ± 0.052	1.656ProGln: 1.656 ± 0.038	3.047ProArg: 3.047 ± 0.052	2.85ProSer: 2.85 ± 0.047	2.418ProThr: 2.418 ± 0.045	4.17ProVal: 4.17 ± 0.059	0.561ProTrp: 0.561 ± 0.019	1.192ProTyr: 1.192 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.58GlnAla: 3.58 ± 0.05	0.169GlnCys: 0.169 ± 0.011	1.271GlnAsp: 1.271 ± 0.031	1.418GlnGlu: 1.418 ± 0.031	0.892GlnPhe: 0.892 ± 0.025	1.994GlnGly: 1.994 ± 0.039	0.485GlnHis: 0.485 ± 0.017	1.767GlnIle: 1.767 ± 0.058	1.024GlnLys: 1.024 ± 0.029	2.464GlnLeu: 2.464 ± 0.049	0.829GlnMet: 0.829 ± 0.031	0.766GlnAsn: 0.766 ± 0.024	1.62GlnPro: 1.62 ± 0.035	0.946GlnGln: 0.946 ± 0.032	2.227GlnArg: 2.227 ± 0.049	1.729GlnSer: 1.729 ± 0.036	1.556GlnThr: 1.556 ± 0.036	1.775GlnVal: 1.775 ± 0.039	0.316GlnTrp: 0.316 ± 0.014	0.516GlnTyr: 0.516 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	7.613ArgAla: 7.613 ± 0.093	0.531ArgCys: 0.531 ± 0.023	4.017ArgAsp: 4.017 ± 0.053	4.405ArgGlu: 4.405 ± 0.077	3.179ArgPhe: 3.179 ± 0.054	5.011ArgGly: 5.011 ± 0.067	1.781ArgHis: 1.781 ± 0.037	4.043ArgIle: 4.043 ± 0.051	2.135ArgLys: 2.135 ± 0.045	8.382ArgLeu: 8.382 ± 0.1	1.902ArgMet: 1.902 ± 0.036	1.697ArgAsn: 1.697 ± 0.038	4.118ArgPro: 4.118 ± 0.066	2.702ArgGln: 2.702 ± 0.048	6.623ArgArg: 6.623 ± 0.1	4.05ArgSer: 4.05 ± 0.058	3.116ArgThr: 3.116 ± 0.047	4.476ArgVal: 4.476 ± 0.067	0.855ArgTrp: 0.855 ± 0.026	1.658ArgTyr: 1.658 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	6.556SerAla: 6.556 ± 0.076	0.403SerCys: 0.403 ± 0.018	3.187SerAsp: 3.187 ± 0.052	3.194SerGlu: 3.194 ± 0.052	2.416SerPhe: 2.416 ± 0.039	6.111SerGly: 6.111 ± 0.075	1.029SerHis: 1.029 ± 0.029	2.76SerIle: 2.76 ± 0.044	1.475SerLys: 1.475 ± 0.034	5.777SerLeu: 5.777 ± 0.062	1.234SerMet: 1.234 ± 0.029	1.303SerAsn: 1.303 ± 0.034	2.979SerPro: 2.979 ± 0.048	1.643SerGln: 1.643 ± 0.037	3.951SerArg: 3.951 ± 0.056	3.0SerSer: 3.0 ± 0.059	2.573SerThr: 2.573 ± 0.048	3.98SerVal: 3.98 ± 0.051	0.692SerTrp: 0.692 ± 0.023	1.239SerTyr: 1.239 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	6.447ThrAla: 6.447 ± 0.087	0.356ThrCys: 0.356 ± 0.017	2.734ThrAsp: 2.734 ± 0.046	2.614ThrGlu: 2.614 ± 0.042	1.998ThrPhe: 1.998 ± 0.036	5.19ThrGly: 5.19 ± 0.064	0.895ThrHis: 0.895 ± 0.023	3.161ThrIle: 3.161 ± 0.056	1.361ThrLys: 1.361 ± 0.037	5.588ThrLeu: 5.588 ± 0.076	1.218ThrMet: 1.218 ± 0.031	1.167ThrAsn: 1.167 ± 0.032	3.101ThrPro: 3.101 ± 0.05	1.146ThrGln: 1.146 ± 0.035	3.351ThrArg: 3.351 ± 0.045	2.8ThrSer: 2.8 ± 0.043	2.779ThrThr: 2.779 ± 0.044	4.449ThrVal: 4.449 ± 0.06	0.524ThrTrp: 0.524 ± 0.018	1.105ThrTyr: 1.105 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	9.812ValAla: 9.812 ± 0.099	0.62ValCys: 0.62 ± 0.017	4.383ValAsp: 4.383 ± 0.06	5.02ValGlu: 5.02 ± 0.057	2.987ValPhe: 2.987 ± 0.058	5.758ValGly: 5.758 ± 0.069	1.27ValHis: 1.27 ± 0.028	3.652ValIle: 3.652 ± 0.054	2.278ValLys: 2.278 ± 0.043	7.005ValLeu: 7.005 ± 0.088	1.812ValMet: 1.812 ± 0.035	1.756ValAsn: 1.756 ± 0.041	3.71ValPro: 3.71 ± 0.05	1.681ValGln: 1.681 ± 0.036	4.67ValArg: 4.67 ± 0.065	4.572ValSer: 4.572 ± 0.055	4.588ValThr: 4.588 ± 0.065	6.326ValVal: 6.326 ± 0.081	0.864ValTrp: 0.864 ± 0.027	1.528ValTyr: 1.528 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.022TrpAla: 1.022 ± 0.029	0.126TrpCys: 0.126 ± 0.009	0.553TrpAsp: 0.553 ± 0.021	0.546TrpGlu: 0.546 ± 0.023	0.489TrpPhe: 0.489 ± 0.019	0.784TrpGly: 0.784 ± 0.025	0.305TrpHis: 0.305 ± 0.014	0.579TrpIle: 0.579 ± 0.018	0.383TrpLys: 0.383 ± 0.018	1.488TrpLeu: 1.488 ± 0.034	0.309TrpMet: 0.309 ± 0.015	0.399TrpAsn: 0.399 ± 0.018	0.63TrpPro: 0.63 ± 0.022	0.568TrpGln: 0.568 ± 0.02	1.045TrpArg: 1.045 ± 0.027	0.763TrpSer: 0.763 ± 0.023	0.687TrpThr: 0.687 ± 0.022	0.658TrpVal: 0.658 ± 0.023	0.206TrpTrp: 0.206 ± 0.015	0.287TrpTyr: 0.287 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.37TyrAla: 2.37 ± 0.038	0.219TyrCys: 0.219 ± 0.013	1.502TyrAsp: 1.502 ± 0.035	1.259TyrGlu: 1.259 ± 0.031	0.894TyrPhe: 0.894 ± 0.026	2.119TyrGly: 2.119 ± 0.036	0.438TyrHis: 0.438 ± 0.018	0.736TyrIle: 0.736 ± 0.022	0.545TyrLys: 0.545 ± 0.021	2.169TyrLeu: 2.169 ± 0.038	0.389TyrMet: 0.389 ± 0.017	0.513TyrAsn: 0.513 ± 0.02	1.1TyrPro: 1.1 ± 0.024	0.71TyrGln: 0.71 ± 0.022	1.761TyrArg: 1.761 ± 0.041	1.135TyrSer: 1.135 ± 0.029	0.964TyrThr: 0.964 ± 0.031	1.605TyrVal: 1.605 ± 0.039	0.326TyrTrp: 0.326 ± 0.014	0.592TyrTyr: 0.592 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4547 proteins (1455190 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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