Amino acid dipepetide frequency for Ophiocordyceps australis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.813AlaAla: 11.813 ± 0.092	1.334AlaCys: 1.334 ± 0.02	4.902AlaAsp: 4.902 ± 0.039	5.167AlaGlu: 5.167 ± 0.053	3.031AlaPhe: 3.031 ± 0.029	6.087AlaGly: 6.087 ± 0.046	2.34AlaHis: 2.34 ± 0.026	4.067AlaIle: 4.067 ± 0.039	4.504AlaLys: 4.504 ± 0.045	8.968AlaLeu: 8.968 ± 0.059	2.518AlaMet: 2.518 ± 0.026	3.079AlaAsn: 3.079 ± 0.033	5.578AlaPro: 5.578 ± 0.063	4.42AlaGln: 4.42 ± 0.041	6.083AlaArg: 6.083 ± 0.048	9.064AlaSer: 9.064 ± 0.058	5.667AlaThr: 5.667 ± 0.043	5.854AlaVal: 5.854 ± 0.043	1.338AlaTrp: 1.338 ± 0.021	2.062AlaTyr: 2.062 ± 0.025	0.001AlaXaa: 0.001 ± 0.001
Cys	1.157CysAla: 1.157 ± 0.018	0.294CysCys: 0.294 ± 0.01	0.72CysAsp: 0.72 ± 0.013	0.632CysGlu: 0.632 ± 0.012	0.595CysPhe: 0.595 ± 0.012	0.971CysGly: 0.971 ± 0.018	0.437CysHis: 0.437 ± 0.012	0.746CysIle: 0.746 ± 0.015	0.579CysLys: 0.579 ± 0.014	1.476CysLeu: 1.476 ± 0.02	0.309CysMet: 0.309 ± 0.009	0.494CysAsn: 0.494 ± 0.011	0.787CysPro: 0.787 ± 0.017	0.587CysGln: 0.587 ± 0.012	0.965CysArg: 0.965 ± 0.016	1.097CysSer: 1.097 ± 0.02	0.692CysThr: 0.692 ± 0.014	0.845CysVal: 0.845 ± 0.015	0.227CysTrp: 0.227 ± 0.008	0.359CysTyr: 0.359 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	6.098AspAla: 6.098 ± 0.043	0.768AspCys: 0.768 ± 0.014	4.972AspAsp: 4.972 ± 0.061	4.701AspGlu: 4.701 ± 0.05	2.194AspPhe: 2.194 ± 0.025	4.376AspGly: 4.376 ± 0.039	1.197AspHis: 1.197 ± 0.018	2.559AspIle: 2.559 ± 0.025	2.868AspLys: 2.868 ± 0.033	4.781AspLeu: 4.781 ± 0.038	1.572AspMet: 1.572 ± 0.022	1.778AspAsn: 1.778 ± 0.021	2.536AspPro: 2.536 ± 0.029	2.027AspGln: 2.027 ± 0.023	2.915AspArg: 2.915 ± 0.031	4.466AspSer: 4.466 ± 0.037	2.617AspThr: 2.617 ± 0.026	3.832AspVal: 3.832 ± 0.032	0.899AspTrp: 0.899 ± 0.013	1.527AspTyr: 1.527 ± 0.022	0.001AspXaa: 0.001 ± 0.0
Glu	6.531GluAla: 6.531 ± 0.06	0.684GluCys: 0.684 ± 0.014	3.262GluAsp: 3.262 ± 0.039	4.437GluGlu: 4.437 ± 0.068	1.651GluPhe: 1.651 ± 0.019	3.243GluGly: 3.243 ± 0.035	1.426GluHis: 1.426 ± 0.02	2.327GluIle: 2.327 ± 0.029	2.992GluLys: 2.992 ± 0.037	5.026GluLeu: 5.026 ± 0.044	1.461GluMet: 1.461 ± 0.018	1.704GluAsn: 1.704 ± 0.023	2.895GluPro: 2.895 ± 0.034	2.859GluGln: 2.859 ± 0.034	3.874GluArg: 3.874 ± 0.042	4.055GluSer: 4.055 ± 0.039	3.302GluThr: 3.302 ± 0.037	3.018GluVal: 3.018 ± 0.031	0.844GluTrp: 0.844 ± 0.017	1.481GluTyr: 1.481 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.181PheAla: 3.181 ± 0.03	0.609PheCys: 0.609 ± 0.014	2.261PheAsp: 2.261 ± 0.028	1.968PheGlu: 1.968 ± 0.022	1.475PhePhe: 1.475 ± 0.022	2.695PheGly: 2.695 ± 0.036	0.812PheHis: 0.812 ± 0.014	1.534PheIle: 1.534 ± 0.02	1.351PheLys: 1.351 ± 0.02	3.044PheLeu: 3.044 ± 0.036	0.751PheMet: 0.751 ± 0.014	1.252PheAsn: 1.252 ± 0.021	1.627PhePro: 1.627 ± 0.022	1.224PheGln: 1.224 ± 0.018	1.785PheArg: 1.785 ± 0.021	2.66PheSer: 2.66 ± 0.026	1.738PheThr: 1.738 ± 0.023	2.384PheVal: 2.384 ± 0.028	0.594PheTrp: 0.594 ± 0.014	0.992PheTyr: 0.992 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	5.774GlyAla: 5.774 ± 0.056	0.909GlyCys: 0.909 ± 0.017	3.702GlyAsp: 3.702 ± 0.037	3.403GlyGlu: 3.403 ± 0.036	2.589GlyPhe: 2.589 ± 0.031	5.612GlyGly: 5.612 ± 0.063	1.917GlyHis: 1.917 ± 0.025	3.179GlyIle: 3.179 ± 0.029	3.112GlyLys: 3.112 ± 0.031	6.202GlyLeu: 6.202 ± 0.048	1.535GlyMet: 1.535 ± 0.023	2.347GlyAsn: 2.347 ± 0.031	3.628GlyPro: 3.628 ± 0.037	3.12GlyGln: 3.12 ± 0.032	4.516GlyArg: 4.516 ± 0.034	5.835GlySer: 5.835 ± 0.047	3.576GlyThr: 3.576 ± 0.041	4.062GlyVal: 4.062 ± 0.039	1.101GlyTrp: 1.101 ± 0.017	1.859GlyTyr: 1.859 ± 0.027	0.001GlyXaa: 0.001 ± 0.0
His	2.275HisAla: 2.275 ± 0.027	0.385HisCys: 0.385 ± 0.011	1.785HisAsp: 1.785 ± 0.023	1.468HisGlu: 1.468 ± 0.02	0.894HisPhe: 0.894 ± 0.014	2.241HisGly: 2.241 ± 0.028	1.134HisHis: 1.134 ± 0.027	1.096HisIle: 1.096 ± 0.017	1.014HisLys: 1.014 ± 0.018	2.466HisLeu: 2.466 ± 0.029	0.591HisMet: 0.591 ± 0.013	0.796HisAsn: 0.796 ± 0.014	1.446HisPro: 1.446 ± 0.022	1.279HisGln: 1.279 ± 0.03	1.625HisArg: 1.625 ± 0.023	1.903HisSer: 1.903 ± 0.023	1.102HisThr: 1.102 ± 0.016	1.879HisVal: 1.879 ± 0.026	0.339HisTrp: 0.339 ± 0.009	0.678HisTyr: 0.678 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	3.748IleAla: 3.748 ± 0.035	0.716IleCys: 0.716 ± 0.014	2.707IleAsp: 2.707 ± 0.027	2.46IleGlu: 2.46 ± 0.031	1.667IlePhe: 1.667 ± 0.026	2.8IleGly: 2.8 ± 0.032	1.088IleHis: 1.088 ± 0.018	2.007IleIle: 2.007 ± 0.03	2.146IleLys: 2.146 ± 0.027	3.802IleLeu: 3.802 ± 0.036	1.01IleMet: 1.01 ± 0.016	1.578IleAsn: 1.578 ± 0.021	2.287IlePro: 2.287 ± 0.026	1.607IleGln: 1.607 ± 0.024	2.501IleArg: 2.501 ± 0.027	3.18IleSer: 3.18 ± 0.031	2.104IleThr: 2.104 ± 0.025	3.004IleVal: 3.004 ± 0.029	0.629IleTrp: 0.629 ± 0.014	1.184IleTyr: 1.184 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.406LysAla: 4.406 ± 0.037	0.51LysCys: 0.51 ± 0.013	2.511LysAsp: 2.511 ± 0.029	2.865LysGlu: 2.865 ± 0.037	1.238LysPhe: 1.238 ± 0.016	2.621LysGly: 2.621 ± 0.03	1.169LysHis: 1.169 ± 0.018	1.841LysIle: 1.841 ± 0.026	2.918LysLys: 2.918 ± 0.047	4.038LysLeu: 4.038 ± 0.038	1.131LysMet: 1.131 ± 0.015	1.413LysAsn: 1.413 ± 0.02	2.722LysPro: 2.722 ± 0.032	2.084LysGln: 2.084 ± 0.025	3.446LysArg: 3.446 ± 0.034	3.334LysSer: 3.334 ± 0.034	2.959LysThr: 2.959 ± 0.03	2.498LysVal: 2.498 ± 0.027	0.609LysTrp: 0.609 ± 0.013	1.109LysTyr: 1.109 ± 0.018	0.001LysXaa: 0.001 ± 0.0
Leu	9.296LeuAla: 9.296 ± 0.063	1.428LeuCys: 1.428 ± 0.022	5.837LeuAsp: 5.837 ± 0.042	5.361LeuGlu: 5.361 ± 0.049	3.138LeuPhe: 3.138 ± 0.034	6.322LeuGly: 6.322 ± 0.044	2.43LeuHis: 2.43 ± 0.028	3.413LeuIle: 3.413 ± 0.04	3.747LeuLys: 3.747 ± 0.034	8.768LeuLeu: 8.768 ± 0.086	1.899LeuMet: 1.899 ± 0.026	2.796LeuAsn: 2.796 ± 0.029	5.509LeuPro: 5.509 ± 0.043	4.037LeuGln: 4.037 ± 0.043	6.138LeuArg: 6.138 ± 0.04	7.352LeuSer: 7.352 ± 0.053	4.451LeuThr: 4.451 ± 0.037	6.403LeuVal: 6.403 ± 0.055	1.198LeuTrp: 1.198 ± 0.021	2.212LeuTyr: 2.212 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.97MetAla: 2.97 ± 0.03	0.27MetCys: 0.27 ± 0.007	1.395MetAsp: 1.395 ± 0.019	1.273MetGlu: 1.273 ± 0.02	0.67MetPhe: 0.67 ± 0.013	1.533MetGly: 1.533 ± 0.021	0.568MetHis: 0.568 ± 0.012	0.812MetIle: 0.812 ± 0.015	0.885MetLys: 0.885 ± 0.014	2.113MetLeu: 2.113 ± 0.027	0.65MetMet: 0.65 ± 0.016	0.667MetAsn: 0.667 ± 0.014	1.493MetPro: 1.493 ± 0.021	1.042MetGln: 1.042 ± 0.018	1.49MetArg: 1.49 ± 0.018	1.975MetSer: 1.975 ± 0.024	1.433MetThr: 1.433 ± 0.019	1.37MetVal: 1.37 ± 0.017	0.271MetTrp: 0.271 ± 0.01	0.493MetTyr: 0.493 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.897AsnAla: 2.897 ± 0.028	0.437AsnCys: 0.437 ± 0.009	1.85AsnAsp: 1.85 ± 0.022	1.703AsnGlu: 1.703 ± 0.022	1.15AsnPhe: 1.15 ± 0.016	2.642AsnGly: 2.642 ± 0.035	0.8AsnHis: 0.8 ± 0.015	1.609AsnIle: 1.609 ± 0.024	1.663AsnLys: 1.663 ± 0.02	2.909AsnLeu: 2.909 ± 0.028	0.882AsnMet: 0.882 ± 0.016	1.24AsnAsn: 1.24 ± 0.029	1.911AsnPro: 1.911 ± 0.027	1.247AsnGln: 1.247 ± 0.019	1.8AsnArg: 1.8 ± 0.022	2.465AsnSer: 2.465 ± 0.025	1.72AsnThr: 1.72 ± 0.021	2.138AsnVal: 2.138 ± 0.024	0.479AsnTrp: 0.479 ± 0.01	0.873AsnTyr: 0.873 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.559ProAla: 5.559 ± 0.06	0.731ProCys: 0.731 ± 0.014	3.3ProAsp: 3.3 ± 0.03	3.227ProGlu: 3.227 ± 0.038	1.856ProPhe: 1.856 ± 0.026	3.916ProGly: 3.916 ± 0.057	1.431ProHis: 1.431 ± 0.022	2.136ProIle: 2.136 ± 0.024	2.391ProLys: 2.391 ± 0.035	5.237ProLeu: 5.237 ± 0.043	1.196ProMet: 1.196 ± 0.02	1.866ProAsn: 1.866 ± 0.023	5.497ProPro: 5.497 ± 0.077	2.713ProGln: 2.713 ± 0.035	3.982ProArg: 3.982 ± 0.04	5.967ProSer: 5.967 ± 0.052	3.394ProThr: 3.394 ± 0.034	3.486ProVal: 3.486 ± 0.036	0.797ProTrp: 0.797 ± 0.014	1.287ProTyr: 1.287 ± 0.02	0.001ProXaa: 0.001 ± 0.0
Gln	4.334GlnAla: 4.334 ± 0.043	0.492GlnCys: 0.492 ± 0.01	2.775GlnAsp: 2.775 ± 0.029	2.668GlnGlu: 2.668 ± 0.029	1.135GlnPhe: 1.135 ± 0.019	2.97GlnGly: 2.97 ± 0.031	1.447GlnHis: 1.447 ± 0.029	1.632GlnIle: 1.632 ± 0.024	1.774GlnLys: 1.774 ± 0.023	3.949GlnLeu: 3.949 ± 0.03	0.939GlnMet: 0.939 ± 0.017	1.304GlnAsn: 1.304 ± 0.02	2.819GlnPro: 2.819 ± 0.038	3.517GlnGln: 3.517 ± 0.106	3.18GlnArg: 3.18 ± 0.033	3.276GlnSer: 3.276 ± 0.035	2.421GlnThr: 2.421 ± 0.025	2.683GlnVal: 2.683 ± 0.027	0.596GlnTrp: 0.596 ± 0.012	1.009GlnTyr: 1.009 ± 0.016	0.001GlnXaa: 0.001 ± 0.001
Arg	5.651ArgAla: 5.651 ± 0.046	0.931ArgCys: 0.931 ± 0.016	3.691ArgAsp: 3.691 ± 0.04	3.628ArgGlu: 3.628 ± 0.042	2.237ArgPhe: 2.237 ± 0.024	4.157ArgGly: 4.157 ± 0.038	2.105ArgHis: 2.105 ± 0.024	2.905ArgIle: 2.905 ± 0.028	3.136ArgLys: 3.136 ± 0.033	6.586ArgLeu: 6.586 ± 0.049	1.328ArgMet: 1.328 ± 0.02	2.133ArgAsn: 2.133 ± 0.023	3.978ArgPro: 3.978 ± 0.044	3.304ArgGln: 3.304 ± 0.031	6.199ArgArg: 6.199 ± 0.06	4.806ArgSer: 4.806 ± 0.044	3.04ArgThr: 3.04 ± 0.025	3.658ArgVal: 3.658 ± 0.034	0.922ArgTrp: 0.922 ± 0.015	1.558ArgTyr: 1.558 ± 0.021	0.001ArgXaa: 0.001 ± 0.001
Ser	7.27SerAla: 7.27 ± 0.051	1.096SerCys: 1.096 ± 0.016	4.245SerAsp: 4.245 ± 0.039	3.757SerGlu: 3.757 ± 0.038	2.807SerPhe: 2.807 ± 0.028	5.392SerGly: 5.392 ± 0.049	2.228SerHis: 2.228 ± 0.025	3.574SerIle: 3.574 ± 0.033	3.575SerLys: 3.575 ± 0.038	7.823SerLeu: 7.823 ± 0.055	1.918SerMet: 1.918 ± 0.025	2.788SerAsn: 2.788 ± 0.033	5.663SerPro: 5.663 ± 0.057	3.569SerGln: 3.569 ± 0.036	5.695SerArg: 5.695 ± 0.047	9.076SerSer: 9.076 ± 0.089	4.98SerThr: 4.98 ± 0.045	4.479SerVal: 4.479 ± 0.034	1.143SerTrp: 1.143 ± 0.02	1.835SerTyr: 1.835 ± 0.023	0.001SerXaa: 0.001 ± 0.0
Thr	5.409ThrAla: 5.409 ± 0.043	0.813ThrCys: 0.813 ± 0.017	2.585ThrAsp: 2.585 ± 0.027	2.545ThrGlu: 2.545 ± 0.029	1.797ThrPhe: 1.797 ± 0.022	3.799ThrGly: 3.799 ± 0.035	1.298ThrHis: 1.298 ± 0.017	2.42ThrIle: 2.42 ± 0.027	2.25ThrLys: 2.25 ± 0.027	5.057ThrLeu: 5.057 ± 0.043	1.282ThrMet: 1.282 ± 0.017	1.711ThrAsn: 1.711 ± 0.022	3.967ThrPro: 3.967 ± 0.053	2.07ThrGln: 2.07 ± 0.026	3.435ThrArg: 3.435 ± 0.03	4.821ThrSer: 4.821 ± 0.044	3.586ThrThr: 3.586 ± 0.048	3.307ThrVal: 3.307 ± 0.033	0.798ThrTrp: 0.798 ± 0.016	1.303ThrTyr: 1.303 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	6.164ValAla: 6.164 ± 0.046	0.951ValCys: 0.951 ± 0.018	3.862ValAsp: 3.862 ± 0.031	3.777ValGlu: 3.777 ± 0.034	2.345ValPhe: 2.345 ± 0.031	3.947ValGly: 3.947 ± 0.034	1.434ValHis: 1.434 ± 0.018	2.531ValIle: 2.531 ± 0.027	2.792ValLys: 2.792 ± 0.031	5.705ValLeu: 5.705 ± 0.054	1.429ValMet: 1.429 ± 0.018	2.002ValAsn: 2.002 ± 0.024	3.631ValPro: 3.631 ± 0.034	2.518ValGln: 2.518 ± 0.026	3.685ValArg: 3.685 ± 0.036	4.658ValSer: 4.658 ± 0.04	3.211ValThr: 3.211 ± 0.034	4.504ValVal: 4.504 ± 0.045	0.84ValTrp: 0.84 ± 0.016	1.635ValTyr: 1.635 ± 0.025	0.001ValXaa: 0.001 ± 0.0
Trp	1.235TrpAla: 1.235 ± 0.022	0.215TrpCys: 0.215 ± 0.007	0.844TrpAsp: 0.844 ± 0.014	0.754TrpGlu: 0.754 ± 0.013	0.478TrpPhe: 0.478 ± 0.012	0.815TrpGly: 0.815 ± 0.016	0.426TrpHis: 0.426 ± 0.01	0.671TrpIle: 0.671 ± 0.013	0.696TrpLys: 0.696 ± 0.013	1.434TrpLeu: 1.434 ± 0.022	0.353TrpMet: 0.353 ± 0.008	0.556TrpAsn: 0.556 ± 0.012	0.72TrpPro: 0.72 ± 0.016	0.654TrpGln: 0.654 ± 0.014	1.096TrpArg: 1.096 ± 0.017	1.017TrpSer: 1.017 ± 0.016	0.916TrpThr: 0.916 ± 0.016	0.771TrpVal: 0.771 ± 0.015	0.278TrpTrp: 0.278 ± 0.01	0.371TrpTyr: 0.371 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.105TyrAla: 2.105 ± 0.022	0.399TyrCys: 0.399 ± 0.012	1.478TyrAsp: 1.478 ± 0.022	1.278TyrGlu: 1.278 ± 0.019	0.99TyrPhe: 0.99 ± 0.016	1.841TyrGly: 1.841 ± 0.026	0.711TyrHis: 0.711 ± 0.014	1.167TyrIle: 1.167 ± 0.018	1.032TyrLys: 1.032 ± 0.017	2.351TyrLeu: 2.351 ± 0.028	0.619TyrMet: 0.619 ± 0.012	0.912TyrAsn: 0.912 ± 0.017	1.274TyrPro: 1.274 ± 0.018	1.042TyrGln: 1.042 ± 0.018	1.541TyrArg: 1.541 ± 0.02	1.904TyrSer: 1.904 ± 0.022	1.34TyrThr: 1.34 ± 0.016	1.445TyrVal: 1.445 ± 0.021	0.399TyrTrp: 0.399 ± 0.011	0.82TyrTyr: 0.82 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.001	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.318XaaXaa: 0.318 ± 0.064

Statistics based on 8168 proteins (4004734 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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